Read by QxMD icon Read

Zhenbin Wang

Heng Zhang, Hao Liu, Zhenbin Shen, Chao Lin, Xuefei Wang, Jing Qin, Xinyu Qin, Jiejie Xu, Yihong Sun
OBJECTIVE: This study was aimed to investigate the prognostic value of tumor-infiltrating neutrophils (TINs) and to generate a predictive model to refine postoperative risk stratification system for patients with gastric cancer. BACKGROUND: TIN presents in various malignant tumors, but its clinical significance in gastric cancer remains obscure. METHODS: The study enrolled 3 independent sets of patients with gastric cancer from 2 institutional medical centers of China...
October 14, 2016: Annals of Surgery
Zhenbin Wang, Qing Wang, Lin Wang, Weidong Xu, Yuanqing He, Yunliang Li, Song He, Haile Ma
BACKGROUND: Collagen hydrolysates (CHs) has been demonstrated to have positive effect on skin photo-aging by topical application or oral ingestion. However, there's little report about its influence on skin chronological aging so far. RESULTS: Nine-month-old female ICR mice were given normal AIN-93M diets containing the CHs (2.5%, 5% and 10%, respectively) from Nile tilapia scale. After 6 months, the collagen content and antioxidant enzymes (superoxide dismutase and glutathione peroxidase) activities significantly increased (p < 0...
October 17, 2016: Journal of the Science of Food and Agriculture
Hongshan Wang, Heng Zhang, Cong Wang, Yong Fang, Xuefei Wang, Weidong Chen, Fenglin Liu, Kuntang Shen, Xinyu Qin, Zhenbin Shen, Yihong Sun
OBJECTIVE: Accurate estimation of lymph node metastasis (LNM) in intramucosal gastric cancer is essential to select less invasive treatment options and even avoid surgery. The aim of this study was to evaluate combined clinicopathological features to predict the presence of LNM. METHODS: A retrospective review of data from 386 intramucosal gastric cancer patients who underwent gastrectomy with extended lymphadenectomy from 2003 to 2010 was conducted. The mutual relation between clinicopathological characteristics and LNM was analyzed...
June 2016: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
Xinglong Wang, Zhenbin Wang, Hongyu Xu, Xiang Biao, Zengqi Yang
BACKGROUND: Porcine reproductive and respiratory syndrome (PRRS) is an important pig endemic disease in pork-producing countries worldwide. The etiology, porcine reproductive and respiratory syndrome virus (PRRSV), is characterized by fast antigen variability. Glycosylated protein 4 (GP4) is a minor protein in PRRSV virion, but contributes to induce protective immune responses. However, the antigenic characterization of PRRSV GP4 and the role of the mutations in this protein in PRRSV evolution are not clear...
2016: Virology Journal
Mingpu Du, Dong Xu, Xuantung Trinh, Shuangyuan Liu, Mei Wang, Yi Zhang, Junmei Wu, Qiaohong Zhou, Zhenbin Wu
Application of extracellular polymeric substances (EPS) solubilization treatment with biosurfactant rhamnolipid (RL) to reduce clogging in constructed wetlands was first conducted in this study. The results showed significant improvement in the solubilization and dispersion of clogging matter following the treatment. And RL dosage of 0.09-0.15g/L altered microbial group make-up and had an overall positive effect on the growth of microorganisms. Moreover, RL was found to enhance EPS dissolution and dispersion, which was beneficial for the release of enzymes embedded in the EPS, and resulted in enhanced pollutant removal...
October 2016: Bioresource Technology
Peike Peng, Weicheng Wu, Junjie Zhao, Shushu Song, Xuefei Wang, Dongwei Jia, Miaomiao Shao, Mingming Zhang, Lili Li, Lan Wang, Fangfang Duan, Ran Zhao, Caiting Yang, Hao Wu, Jie Zhang, Zhenbin Shen, Yuanyuan Ruan, Jianxin Gu
Calpain-8 and calpain-9 belong to the family of calcium-dependent cysteine proteases, which are highly expressed in the stomach. However, the roles of calpain-8 and calpain-9 in gastric tumorigenesis remain little understood. Herein, we demonstrated that calpain-9 was generally decreased in gastric cancer cell lines and primary tumor tissues, while calpain-8 expression was not significantly altered. Calpain-9, but not calpain-8, induced cell cycle arrest in the G1 phase and cellular apoptosis in vitro, and it attenuated the growth of subcutaneous tumor xenografts in vivo...
2016: Scientific Reports
Nan You, Jing Li, Zhenbin Gong, Xiaobing Huang, Weiwei Wang, Liang Wang, Ke Wu, Lu Zheng
Our previous studies provided evidence that COMMD7 was associated with tumor progression in human solid cancer. Herein, we aimed to investigate its expression pattern, clinical significance, and biological function in pancreatic ductal adenocarcinoma (PDAC). We found that high COMMD7 expression was specifically detected in PDAC tissues and PDAC cell lines. In addition, COMMD7 overexpression positively correlated with histological differentiation and tumor node metastasis (TNM) stage. Patients with high COMMD7 expression had significantly poorer overall survival, and high COMMD7 expression was an independent predictor of poor prognosis...
June 28, 2016: Molecular Carcinogenesis
Dan Zhang, Chuan Wang, Liping Zhang, Dong Xu, Biyun Liu, Qiaohong Zhou, Zhenbin Wu
Long-term use of chlorpyrifos poses a potential threat to the environment that cannot be ignored, yet little is known about the succession of substrate microbial communities in constructed wetlands (CWs) under chlorpyrifos stress. Six pilot-scale CW systems receiving artificial wastewater containing 1mg/L chlorpyrifos were established to investigate the effects of chlorpyrifos and wetland vegetation on the microbial metabolism pattern of carbon sources and community structure, using BIOLOG and denaturing gradient gel electrophoresis (DGGE) approaches...
June 2016: Journal of Environmental Sciences (China)
Ji Wang, Ming Shan, Tong Liu, Qingyu Shi, Zhenbin Zhong, Wei Wei, Da Pang
PURPOSE: This study was designed to assess the protein levels of transformation/transcription domain-associated protein (TRRAP) in invasive ductal breast carcinomas, and investigated the association between TRRAP and the clinicopathological features of breast cancer. METHODS: We examined TRRAP protein expression in 470 breast cancer tissues and normal breast tissues by tissue microarray to study the correlation between TRRAP expression and clinicopathological features...
March 2016: Journal of Breast Cancer
Dan Zhang, Hongyan Li, Jinshe Wang, Hengyou Zhang, Zhenbin Hu, Shanshan Chu, Haiyan Lv, Deyue Yu
Phosphorus (P) is essential for all living cells and organisms, and low-P stress represents a major constraint on plant growth and yield worldwide. Soybean is an important economical resource of protein and oil for human and animals, and soybean is also a high-P demand species that is sensitive to low-P stress, which is considered a major constraint on soybean production. However, P efficiency is an important complex quantitative trait involving multiple genes, and the mechanisms underlying soybean P efficiency are largely unknown...
2016: Frontiers in Plant Science
Iek-Heng Chu, Han Nguyen, Sunny Hy, Yuh-Chieh Lin, Zhenbin Wang, Zihan Xu, Zhi Deng, Ying Shirley Meng, Shyue Ping Ong
The Li7P3S11 glass-ceramic is a promising superionic conductor electrolyte (SCE) with an extremely high Li(+) conductivity that exceeds that of even traditional organic electrolytes. In this work, we present a combined computational and experimental investigation of the material performance limitations in terms of its phase and electrochemical stability, and Li(+) conductivity. We find that Li7P3S11 is metastable at 0 K but becomes stable at above 630 K (∼360 °C) when vibrational entropy contributions are accounted for, in agreement with differential scanning calorimetry measurements...
March 2016: ACS Applied Materials & Interfaces
Hao Liu, Heng Zhang, Zhenbin Shen, Chao Lin, Xuefei Wang, Jing Qin, Xinyu Qin, Jiejie Xu, Yihong Sun
Clinical significance of diametrically polarized tumor-associated macrophages in gastric cancer has been elucidated in our previous study, whereas the role of cytokines that orchestrate tumor-associated macrophages polarization in gastric cancer remains elusive. The study aims to evaluate the prognostic value of colony-stimulating factor-1 expression in patients with gastric cancer. We examined the colony-stimulating factor-1 expression in tumor tissues by immunohistochemical staining in retrospectively enrolled 365 patients with gastric cancer undergoing gastrectomy at Zhongshan Hospital during 2008...
March 2016: Medicine (Baltimore)
Long Xin, Chun Zhang, Fuhua Zhong, Shunwu Fan, Wei Wang, Zhenbin Wang
BACKGROUND: The rabbit disc model is useful for the study of intervertebral disc (IVD) degeneration and experimental therapeutic interventions. The annulotomy-induced disc models present several drawbacks, particularly an excessive disruption of disc integrity and a rapidly disc degeneration; therefore, this study sought to establish a minimal invasive annulotomy for induction of disc degeneration model, combined to annulus repair using implantation of a PLGA (poly lactic-co-glycolic acid) plug...
2016: European Journal of Medical Research
Ming Shan, Huizi Yin, Junnan Li, Xiaobo Li, Dong Wang, Yonghui Su, Ming Niu, Zhenbin Zhong, Ji Wang, Xianyu Zhang, Wenli Kang, Da Pang
Detection of breast cancer at an early stage is the key for successful treatment and improvement of outcome. However the limitations of mammography are well recognized, especially for those women with premenopausal breast cancer. Novel approaches to breast cancer screening are necessary, especially in the developing world where mammography is not feasible. In this study, we examined the promoter methylation of six genes (SFN, P16, hMLH1, HOXD13, PCDHGB7 and RASSF1a) in circulating free DNA (cfDNA) extracted from serum...
April 5, 2016: Oncotarget
Hao Liu, Zhenbin Shen, Zhenglin Wang, Xuefei Wang, Heng Zhang, Jing Qin, Xinyu Qin, Jiejie Xu, Yihong Sun
Clinical significance of 2,3-dioxygenase (IDO) has been studied in types of tumors, but the role that IDO played in gastric adenocarcinoma (GAC) is still unclear. Here, we aim to investigate the prognostic value of IDO expression in patients with GAC. We examined intratumoral IDO expression in retrospectively enrolled 357 patients with GAC undergoing gastrectomy at Zhongshan Hospital of Fudan University in 2008 by immunohistochemical staining. The Kaplan-Meier method and Cox regression models were used to evaluate the prognostic value of IDO expression and its association with clinical pathological factors...
2016: Scientific Reports
Daoming Huan, Zhiquan Wang, Zhenbin Wang, Ranran Peng, Changrong Xia, Yalin Lu
Driven by the mounting concerns on global warming and energy crisis, intermediate temperature solid-oxide fuel cells (IT-SOFCs) have attracted special attention for their high fuel efficiency, low toxic gas emission, and great fuel flexibility. A key obstacle to the practical operation of IT-SOFCs is their sluggish oxygen reduction reaction (ORR) kinetics. In this work, we applied a new two-layered Ruddlesden-Popper (R-P) oxide, Sr3Fe2O7-δ (SFO), as the material for oxygen ion conducting IT-SOFCs. Density functional theory calculation suggested that SFO has extremely low oxygen ion formation energy and considerable energy barrier for O(2-) diffusion...
February 2016: ACS Applied Materials & Interfaces
Tao Yu, Jiayang Zhang, Xiaobing Jiang, Junmei Wu, Zhigang Dai, Zhenbin Wu, Yu Liang, Xuannian Wang
INTRODUCTION: Escherichia coli is a commensal bacterium in humans, animals, and the environment that is one of the microorganisms commonly resistant to antimicrobials. Cooked meat products, which are popular in China, are easily contaminated by E. coli during processing and storage. METHODOLOGY: In this study, a total of 75 E. coli isolates from cooked meat products in Henan province, China, were assayed for the presence of and horizontal transfer of class 1 integrons...
January 2016: Journal of Infection in Developing Countries
ZhenBin Zhong, Ming Shan, Ji Wang, Tong Liu, QingYu Shi, Da Pang
BACKGROUND: Wingless-type MMTV integration site family member 5A (Wnt5a) has been documented to either overexpress or be lost in several malignancies. Our study aimed to investigate the expression and clinical significance of Wnt5a protein in triple-negative breast cancer (TNBC). MATERIAL/METHODS: By using immunohistochemistry, Wnt5a expression was evaluated in 90 TNBC specimens. The association between Wnt5a expression and clinic-pathological factors was assessed by using the chi-square test...
2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Zhiqiang Chen, Lixing Cao, Zehuai Wen, Naiqiang Cui, Naiqing Li, Jianxing Xie, Zhijian Tan, Zhenbin Luo, Shusheng Wang, You Qin, Xiuhua Chen, Zhenhua Xu, Aihua Ou, Wenfan Shang, Zhi Jiang, Qicheng Chen
BACKGROUND: The importance of postoperative gastrointestinal function recovery is being increasingly recognized. In this multi-center randomized controlled study, we evaluated the efficacy and safety of Evodia hot compress (ECS) plus electro-acupuncture (EA) for patients who developed postoperative gastrointestinal tract dysfunction after abdominal surgery. METHODS: 1009 patients who developed postoperative gastrointestinal tract dysfunction after abdominal surgery were enrolled...
2015: International Journal of Clinical and Experimental Medicine
Hao Liu, Heng Zhang, Zhenbin Shen, Xuefei Wang, Zhenglin Wang, Jiejie Xu, Yihong Sun
BACKGROUND: Clinical significance of Notch1 activation in gastric cancer has been elucidated in our previous study, but the role of its ligands remains obscure. This study aims to evaluate the prognostic value of Jagged1 expression in patients with gastric cancer. METHODS: We examined Jagged1 expression in tumor and nontumor tissues in retrospectively enrolled 302 patients with gastric cancer undergoing gastrectomy at Zhongshan Hospital of Fudan University in 2008 by immunohistochemical staining...
2015: International Journal of Clinical and Experimental Medicine
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"