keyword
MENU ▼
Read by QxMD icon Read
search

Stewart acid-base

keyword
https://www.readbyqxmd.com/read/28301845/dietary-intakes-of-arachidonic-acid-and-docosahexaenoic-acid-in-early-life-with-a-special-focus-on-complementary-feeding-in-developing-countries
#1
Stewart Forsyth, Sheila Gautier, Norman Salem
BACKGROUND: In developing countries, dietary intakes of arachidonic acid (ARA) and docosahexaenoic acid (DHA) in early life are lower than current recommended levels. This review specifically focusses on the contribution that complementary feeding makes to ARA and DHA intakes in medium- to low-income countries. The aims of the review are (1) to determine the availability of ARA and DHA food sources in developing countries, (2) to estimate the contribution of complementary feeding to dietary intakes of ARA and DHA in infants aged 6-36 months, and (3) to relate the dietary ARA and DHA intake data to key socioeconomic and health indicators...
March 17, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28289910/acid-base-disturbances-in-nephrotic-syndrome-analysis-using-the-co2-hco3-method-traditional-boston-model-and-the-physicochemical-method-stewart-model
#2
Tomomichi Kasagi, Hirokazu Imai, Naoto Miura, Keisuke Suzuki, Masabumi Yoshino, Hironobu Nobata, Takuhito Nagai, Shogo Banno
BACKGROUND: The Stewart model for analyzing acid-base disturbances emphasizes serum albumin levels, which are ignored in the traditional Boston model. We compared data derived using the Stewart model to those using the Boston model in patients with nephrotic syndrome. METHODS: Twenty-nine patients with nephrotic syndrome and six patients without urinary protein or acid-base disturbances provided blood and urine samples for analysis that included routine biochemical and arterial blood gas tests, plasma renin activity, and aldosterone...
March 13, 2017: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/28274230/appraisal-of-phytochemical-and-in-vitro-biological-attributes-of-an-unexplored-folklore-rhus-punjabensis-stewart
#3
Saira Tabassum, Madiha Ahmed, Bushra Mirza, Muhammad Naeem, Muhammad Zia, Zabta Khan Shanwari, Gul Majid Khan
BACKGROUND: The role of plants for discovery of therapeutic potential accentuates the need to know their biological attributes. The present study aims to comprehend the biological attributes of Rhus punjabensis, an unexplored traditional medicinal plant. METHODS: Leaf and stem extracts of R. punjabensis prepared in 11 different organic solvents are evaluated for multimode antioxidant potential, total phenolic and flavonoid contents were determined through colorimetric assays, HPLC-DAD analysis was carried out for quantification of various polyphenols in extracts...
March 9, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28177094/-analysis-of-the-parameters-traditional-or-not-for-the-evaluation-of-the-metabolic-acidosis
#4
Caterina Urso, Salvatore Brucculeri, Caterina Carollo, Gregorio Caimi
Despite huge progress in acidbase knowledge, several confusing, irrational and controversial issues still remain. Acid-base disturbances have been usually evaluated with the traditional Henderson-Hasselbach method and with BE evaluation that seem inadequate since they define the magnitude of metabolic acidosis rather than its cause. Some studies have shown that the traditional approach is often not able to highlight the complicated acid-base disorders in critically ill patients; in these subjects, the possibility to identify tissue acids could offer a greater prognostic value than the evaluation of traditional parameters...
January 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28043136/macromolecular-prodrugs-of-ribavirin-structure-function-correlation-as-inhibitors-of-influenza-infectivity
#5
Camilla Frich Riber, Tracey M Hinton, Paulina Gajda, Kaja Zuwala, Martin Tolstrup, Cameron Stewart, Alexander N Zelikin
The requirement for new antiviral therapeutics is an ever present need. Particularly lacking are broad spectrum antivirals that have low toxicity. We develop such agents based on macromolecular prodrugs whereby both the polymer chain and the drug released from the polymer upon cell entry have antiviral effects. Specifically, macromolecular prodrugs were designed herein based on poly(methacrylic acid) and ribavirin. Structure-function parameter space was analyzed via the synthesis of 10 polymer compositions varied by molar mass and drug content...
January 3, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/27990831/-clinical-evaluation-of-acid-base-status-henderson-hasselbalch-or-stewart-fencl-approach
#6
Karel Matoušovic, Jan Havlín, Otto Schück
Two approaches have been used in clinical evaluation the acid-base status: traditional (bicarbonate-centered) is based on the Henderson-Hasselbalch equation complemented by calculation of the anion gap, and more recent quantitative approach proposed by Stewart and Fencl. The latter method defines the three independent variables, which regulate pH. These include: the difference between the sum of charges carried by strong plasma cations and anions termed the strong ion difference - SID (decrease causes acidosis, and vice versa); the total concentration of the weak non-volatile acids [Atot] (inorganic phosphate and albumin, decrease causes alkalosis and vice versa), and pCO2...
2016: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/27861448/an-app-to-calculate-bedside-stewart-acid-base-equations
#7
John H P Friesen
No abstract text is available yet for this article.
December 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27760042/use-of-elements-of-the-stewart-model-strong-ion-approach-sid3-sid4-atot-a-side-and-sig-for-the-diagnostics-of-respiratory-acidosis-in-brachycephalic-dogs
#8
P Sławuta, G Sapikowski, B Sobieraj
Buffer systems of blood and tissues, which have the ability to bind with and give up hydrogen ions, participate in maintaining the acid-base balance (ABB) of the organism. According to the classic model, the system of carbonic acid and bicarbonates, where the first component serves the role of an acid and the second a base, determines plasma pH. The so-called Stewart model, which assumes that ions in blood serum can be separated into completely dissociated - nonbuffer and not dissociated - buffer ions which may give up or accept H+ions, also describes the ABB of the organism...
September 1, 2016: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/27753644/tryptophan-and-cysteine-mutations-in-m1-helices-of-%C3%AE-1%C3%AE-3%C3%AE-2l-%C3%AE-aminobutyric-acid-type-a-receptors-indicate-distinct-intersubunit-sites-for-four-intravenous-anesthetics-and-one-orphan-site
#9
Anahita Nourmahnad, Alex T Stern, Mayo Hotta, Deirdre S Stewart, Alexis M Ziemba, Andrea Szabo, Stuart A Forman
BACKGROUND: γ-Aminobutyric acid type A (GABAA) receptors mediate important effects of intravenous general anesthetics. Photolabel derivatives of etomidate, propofol, barbiturates, and a neurosteroid get incorporated in GABAA receptor transmembrane helices M1 and M3 adjacent to intersubunit pockets. However, photolabels have not been consistently targeted at heteromeric αβγ receptors and do not form adducts with all contact residues. Complementary approaches may further define anesthetic sites in typical GABAA receptors...
December 2016: Anesthesiology
https://www.readbyqxmd.com/read/27638212/palaeoproteomic-evidence-identifies-archaic-hominins-associated-with-the-ch%C3%A3-telperronian-at-the-grotte-du-renne
#10
Frido Welker, Mateja Hajdinjak, Sahra Talamo, Klervia Jaouen, Michael Dannemann, Francine David, Michèle Julien, Matthias Meyer, Janet Kelso, Ian Barnes, Selina Brace, Pepijn Kamminga, Roman Fischer, Benedikt M Kessler, John R Stewart, Svante Pääbo, Matthew J Collins, Jean-Jacques Hublin
In Western Europe, the Middle to Upper Paleolithic transition is associated with the disappearance of Neandertals and the spread of anatomically modern humans (AMHs). Current chronological, behavioral, and biological models of this transitional period hinge on the Châtelperronian technocomplex. At the site of the Grotte du Renne, Arcy-sur-Cure, morphological Neandertal specimens are not directly dated but are contextually associated with the Châtelperronian, which contains bone points and beads. The association between Neandertals and this "transitional" assemblage has been controversial because of the lack either of a direct hominin radiocarbon date or of molecular confirmation of the Neandertal affiliation...
October 4, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27636585/stewart-versus-traditional-approach-to-acid-base-disorders
#11
Michael Emmett
No abstract text is available yet for this article.
October 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27621395/pancreox-a-randomized-phase-iii-study-of-5-fluorouracil-leucovorin-with-or-without-oxaliplatin-for-second-line-advanced-pancreatic-cancer-in-patients-who-have-received-gemcitabine-based-chemotherapy
#12
Sharlene Gill, Yoo-Joung Ko, Christine Cripps, Annie Beaudoin, Sukhbinder Dhesy-Thind, Muhammad Zulfiqar, Pawel Zalewski, Thuan Do, Pablo Cano, Wendy Yin Han Lam, Scot Dowden, Helene Grassin, John Stewart, Malcolm Moore
PURPOSE: The standard of care for second-line therapy in patients with advanced pancreatic cancer after gemcitabine-based therapy is not clearly defined. The CONKO-003 phase III study reported a survival benefit with second-line fluorouracil (FU) and oxaliplatin using the oxaliplatin, folinic acid, and FU (OFF) regimen.(1) PANCREOX was a phase III multicenter trial to evaluate the benefit of FU and oxaliplatin administered as modified FOLFOX6 (mFOLFOX6; infusional fluorouracil, leucovorin, and oxaliplatin) versus infusional FU/leucovorin (LV) in this setting...
September 12, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/27611634/non-targeted-metabolite-profiling-highlights-the-potential-of-strawberry-leaves-as-a-resource-for-specific-bioactive-compounds
#13
Anna Kårlund, Kati Hanhineva, Marko Lehtonen, Gordon J McDougall, Derek Stewart, Reijo O Karjalainen
BACKGROUND: The non-edible parts of horticultural crops, such as leaves, contain substantial amounts of valuable bioactive compounds which are currently only little exploited. For example, strawberry (Fragaria × ananassa) leaves may be a promising bioresource for diverse health-related applications. However, product standardization sets a real challenge, especially when the leaf material comes from varying cultivars. The first step towards better quality control of berry fruit leaf-based ingredients and supplements is to understand metabolites present and their stability in different plant cultivars, so this study surveyed the distribution of potentially bioactive strawberry leaf metabolites in six different strawberry cultivars...
September 9, 2016: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/27569705/metabolomic-determination-of-pathogenesis-of-late-onset-preeclampsia
#14
Ray O Bahado-Singh, Argyro Syngelaki, Rupsari Mandal, Stewart F Graham, Ranjit Akolekar, Beomsoo Han, Trent C Bjondahl, Edison Dong, Samuel Bauer, Zeynep Alpay-Savasan, Onur Turkoglu, Dotun Ogunyemi, Liona C Poon, David S Wishart, Kypros H Nicolaides
OBJECTIVE: Our primary objective was to apply metabolomic pathway analysis of first trimester maternal serum to provide an insight into the pathogenesis of late-onset preeclampsia (late-PE) and thereby identify plausible therapeutic targets for PE. METHODS: NMR-based metabolomics analysis was performed on 29 cases of late-PE and 55 unaffected controls. In order to achieve sufficient statistical power to perform the pathway analysis, these cases were combined with a group of previously analyzed specimens, 30 late-PE cases and 60 unaffected controls...
March 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27562561/chloride-content-of-solutions-used-for-regional-citrate-anticoagulation-might-be-responsible-for-blunting-correction-of-metabolic-acidosis-during-continuous-veno-venous-hemofiltration
#15
Rita Jacobs, Patrick M Honore, Marc Diltoer, Herbert D Spapen
BACKGROUND: Citrate, the currently preferred anticoagulant for continuous veno-venous hemofiltration (CVVH), may influence acid-base equilibrium. METHODS: The effect of 2 different citrate solutions on acid-base status was assessed according to the Stewart-Figge approach in two consecutive cohorts of critically ill adult patients. The first group received Prismocitrate 10/2 (PC10/2; 10 mmol citrate/L). The next group was treated with Prismocitrate 18/0 (PC18; 18 mmol citrate/L)...
August 26, 2016: BMC Nephrology
https://www.readbyqxmd.com/read/27546763/the-prognostic-value-of-the-strong-ion-gap-in-acute-pancreatitis
#16
Xiao Shen, Lu Ke, Dongliang Yang, Jing Sun, Zhihui Tong, Baiqiang Li, Gang Li, Weiqin Li, Jieshou Li, Rinaldo Bellomo
PURPOSE: In this study, we aimed to evaluate the predictive value of Stewart-derived parameters for the development of severe type of acute pancreatitis (AP) and for AP-related mortality. METHODS: We studied 186 patients admitted to the hospital with AP. We performed blood gas and biochemical analysis for each patient on admission. We calculated multiple metrics according to the Stewart's acid-base theory and assessed their accuracy as predictors of AP severity and mortality...
July 9, 2016: Journal of Critical Care
https://www.readbyqxmd.com/read/27465935/effect-of-laparoscopic-sleeve-gastrectomy-on-fasting-gastrointestinal-pancreatic-and-adipose-derived-hormones-and-on-non-esterified-fatty-acids
#17
John E Farey, Tamara C Preda, Oliver M Fisher, Angelique J Levert-Mignon, Rebecca L Stewart, Elisabeth Karsten, Benjamin R Herbert, Michael M Swarbrick, Reginald V Lord
BACKGROUND: Alterations in gastrointestinal, pancreatic, and adipose hormone levels may have a greater role in weight loss than initially appreciated. The laparoscopic sleeve gastrectomy (LSG) operation is now the most frequently performed bariatric operation in many countries, but there are relatively few data regarding its molecular effects. We sought to characterize the effect of LSG on fasting plasma levels of selected hormones and on non-esterified fatty acids (NEFA), and to compare these to levels in non-obese control individuals...
February 2017: Obesity Surgery
https://www.readbyqxmd.com/read/27447733/metabolomics-analysis-of-hormone-responsive-and-triple-negative-breast-cancer-cell-responses-to-paclitaxel-identify-key-metabolic-differences
#18
Delisha A Stewart, Jason H Winnike, Susan L McRitchie, Robert F Clark, Wimal W Pathmasiri, Susan J Sumner
To date, no targeted therapies are available to treat triple negative breast cancer (TNBC), while other breast cancer subtypes are responsive to current therapeutic treatment. Metabolomics was conducted to reveal differences in two hormone receptor-negative TNBC cell lines and two hormone receptor-positive Luminal A cell lines. Studies were conducted in the presence and absence of paclitaxel (Taxol). TNBC cell lines had higher levels of amino acids, branched-chain amino acids, nucleotides, and nucleotide sugars and lower levels of proliferation-related metabolites like choline compared with Luminal A cell lines...
September 2, 2016: Journal of Proteome Research
https://www.readbyqxmd.com/read/27410514/old-and-new-approaches-to-the-interpretation-of-acid-base-metabolism-starting-from-historical-data-applied-to-diabetic-acidosis
#19
Roberto Mioni, Alessandra Marega, Marco Lo Cicero, Domenico Montanaro
The approach to acid-base chemistry in medicine includes several methods. Currently, the two most popular procedures are derived from Stewart's studies and from the bicarbonate/BE-based classical formulation. Another method, unfortunately little known, follows the Kildeberg theory applied to acid-base titration. By using the data produced by Dana Atchley in 1933, regarding electrolytes and blood gas analysis applied to diabetes, we compared the three aforementioned methods, in order to highlight their strengths and their weaknesses...
November 2016: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/27319095/-kidney-fluid-and-acid-base-balance
#20
REVIEW
Naohiro Shioji, Masao Hayashi, Hiroshi Morimatsu
Kidneys play an important role to maintain human homeostasis. They contribute to maintain body fluid, electrolytes, and acid-base balance. Especially in fluid control, we, physicians can intervene body fluid balance using fluid resuscitation and diuretics. In recent years, one type of fluid resuscitation, hydroxyl ethyl starch has been extensively studied in the field of intensive care. Although their effects on fluid resuscitation are reasonable, serious complications such as kidney injury requiring renal replacement therapy occur frequently...
May 2016: Masui. the Japanese Journal of Anesthesiology
keyword
keyword
87565
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"