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Blood gas and neonate

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https://www.readbyqxmd.com/read/27918385/neurally-adjusted-ventilatory-assist-in-preterm-infants-with-established-or-evolving-bronchopulmonary-dysplasia-on-high-intensity-mechanical-ventilatory-support-a-single-center-experience
#1
Young Hwa Jung, Han-Suk Kim, Juyoung Lee, Seung Han Shin, Ee-Kyung Kim, Jung-Hwan Choi
OBJECTIVES: The aim of the present study was to report possible improvements in ventilator variables associated with a transition from synchronized intermittent mandatory ventilation to neurally adjusted ventilatory assist in preterm infants with bronchopulmonary dysplasia who required a high level of mechanical ventilatory support in a single center. DESIGN: Retrospective study. SETTING: Neonatal ICU. PATIENTS: Twenty-nine preterm infants with a median gestational age of 25...
December 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27914513/fatty-acid-profile-in-cord-blood-of-neonates-born-to-optimally-controlled-gestational-diabetes-mellitus
#2
Pauline Léveillé, Jean-Luc Ardilouze, Jean-Charles Pasquier, Charles Deacon, Kevin Whittingstall, Mélanie Plourde
OBJECTIVE: To evaluate the fatty acid profile of cord blood phospholipids (PL), cholesteryl esters (CE), triglycerides (TG) and non-esterified fatty acids (NEFA) in neonates born to mothers with gestational diabetes mellitus (GDM) compared to non-diabetic mothers. METHODS: The offspring of 30 pregnant women (15 non-diabetic controls, 15 with diet- or insulin-controlled GDM) were recruited before delivery. Cord blood was collected. After lipid extraction, PL, CE, TG and NEFA were separated by thin layer chromatography and analysed by gas chromatography...
December 2016: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/27884069/risk-factors-of-incomplete-apgar-score-and-umbilical-cord-blood-gas-analysis-a-retrospective-observational-study
#3
Anne A C van Tetering, Joost van de Ven, Annemarie F Fransen, Jeanne P Dieleman, Pieter J van Runnard Heimel, S Guid Oei
OBJECTIVE: To investigate whether incomplete umbilical cord blood gas (UCBG) analysis occurs more often than the incomplete reporting of the Apgar score, and risk factors associated with the incomplete values. METHODS: A total of 8824 infants born alive after 26 weeks' gestation between January 2009 and April 2013 were included. We extracted data on five-minute Apgar score, UCBG analysis, gestational age, mode of delivery, time of delivery and multiple pregnancy...
November 24, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27882025/no-inhalation-in-combination-with-high-frequency-ventilation-treatment-in-the-treatment-of-neonatal-severe-respiratory-failure
#4
Xiaohui Guo, Yanfeng Sun, Jing Miao, Min Cui, Jiangbo Wang, Shuzhen Han
OBJECTIVE: To discuss over NO inhalation (iNO) in combination with high frequency ventilation treatment in relieving clinical symptoms and respiratory state of patients with neonatal severe respiratory failure. METHODS: Ninety newborns with severe respiratory failure who received treatment in our hospital were selected for this study. They were divided into research group and control group according to visiting time. Patients in the control group were given conventional treatment in combination with high-frequency oscillatory ventilation, while patients in the research group were given iNO for treatment additionally besides the treatment the same as the control group...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27854117/treatment-of-neonates-with-respiratory-distress-syndrome-by-proportional-assist-ventilation-plus-synchronized-intermittent-mandatory-ventilation-a-comparison-study
#5
Rong Wu, Zhao F Tian, Xiang Y Kong, Shao D Hua, Jin H Hu, Guo F Zhen
BACKGROUND: The proportion assisted ventilation (PAV) can improve patient-ventilator interaction, reduce the incidence of end-expiratory asynchrony and increase the time of synchrony. PAV could compensate for the leaks by Elastic and resistive unloading and thus is ideal for neonates with uncuffed airways. The aim of this study was to compare the relevant clinical parameters of neonates with respiratory distress syndrome(RDS) who are surported by PAV plus synchronized intermittent mandatory ventilation (SIMV) and SIMV...
November 17, 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/27817953/mechanically-assisted-bidirectional-cavopulmonary-shunt-in-neonates-and-infants-an-acute-human-pilot-study
#6
Osami Honjo, Sandra L Merklinger, John B Poe, Anne-Marie Guerguerian, Hargen Zhang, Katherine L Taylor, Glen S Van Arsdell
OBJECTIVE: Poor survival following surgical palliation for hypoplastic left heart syndrome (HLHS) raises the question of the need for a paradigm shift. This is the first human study to investigate the possibility of primary "in-series" palliation in neonates and infants with HLHS in an acute setting with the aid of 2 types of mechanical assist: superior vena cava (SVC)-to-pulmonary artery (PA) pump assist and SVC-to-right atrium (RA) oxygenation assist. METHODS: By rearranging the cannula sites and flow rates for modified ultrafiltration, 2 types of mechanically assisted bidirectional cavopulmonary shunt (BCPS) circulation were simulated for 20 minutes...
September 28, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27817783/-pancytopenia-and-metabolic-decompensation-in-a-neonate
#7
Jian-Qiang Tan, Da-Yu Chen, Zhen-Qin Mo, Zhe-Tao Li, Ji-Wei Huang, Ren Cai, Ti-Zhen Yan
A 9-day-old male patient was admitted to the hospital because of cough, anhelation, feeding difficulty and lethargy. The diagnostic examinations indicated pulmonary infection, severe metabolic acidosis, hyperglycemia, hyperammonemia and pancytopenia in the patient. Blood and urine screening and isovaleryl-CoA dehydrogenase (IVD) gene detection for inherited metabolic diseases were performed to clarify the etiology. Tandem mass spectrometric screening for blood showed an elevated isovalerylcarnitine (C5) level...
November 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/27817768/-clinical-effect-of-high-frequency-oscillatory-ventilation-combined-with-pulmonary-surfactant-in-treatment-of-neonatal-severe-meconium-aspiration-syndrome-complicated-by-pulmonary-hemorrhage
#8
Jing Huang, Xin-Zhu Lin, Zhi Zheng
OBJECTIVE: To study the clinical effect and safety of high-frequency oscillatory ventilation (HFOV) combined with pulmonary surfactant (PS) in the treatment of neonatal severe meconium aspiration syndrome (MAS) complicated by neonatal pulmonary hemorrhage (NPH). METHODS: A total of 48 children with severe MAS complicated by NPH were enrolled, and a retrospective analysis was performed for the clinical effects of HFOV+PS (trial group, 25 children) and HFOV alone (control group, 23 children)...
November 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/27756160/ph-base-deficit-or-lactate-which-is-better-for-predicting-neonatal-morbidity
#9
Sabina Martí Gamboa, Jara Pascual Mancho, María Rodrigo Rodríguez, Julia Ruiz Sada, Sergio Castán Mateo
OBJECTIVE: To determine which parameter of the umbilical arterial cord gas analysis, pH, base deficit (BD) or lactate has a bigger predictive ability for neonatal morbidity at term. METHOD: We conducted a four year retrospective cohort study including all non-anomalous, singleton, vertex, term births with neonatal acidemia (umbilical arterial cord gas pH ≤ 7.1). The primary outcomes were a composite neurological morbidity and a composite systemic morbidity. The predictive ability of lactate, BD and pH were compared using ROC curves...
October 19, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27748297/association-of-organochlorine-pesticides-with-the-mrna-expression-of-tumour-necrosis-factor-alpha-tnf-%C3%AE-cyclooxygenase-2-cox-2-genes-in-idiopathic-preterm-birth
#10
Vipin Tyagi, M D Mustafa, Tusha Sharma, B D Banerjee, Rafat S Ahmed, A K Tripathi, Kiran Guleria
BACKGROUND & OBJECTIVES: Preterm birth (PTB) is an important cause of prenatal death, neonatal morbidity and mortality and adult illness. Increased inflammation occurs in normal parturition, and inflammatory cytokines and oxidative stress are found to be higher in PTB cases. The present study was planned to investigate the association of organochlorine pesticides (OCPs) with mRNA expression of inflammatory pathway genes such as tumour necrosis factor-alpha (TNF-α) and cyclooxygenase-2 (COX-2) in preterm delivery (PTD) cases...
June 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27723920/antenatally-detected-congenital-pulmonary-airway-malformations-the-oxford-experience
#11
Hemanshoo Sudhir Thakkar, Jonathan Durell, Subhasis Chakraborty, Bianca-Lea Tingle, Arnwald Choi, Darren J Fowler, Steve J Gould, Lawrence Impey, Kokila Lakhoo
Congenital airway pulmonary malformations are increasingly being diagnosed, but their management continues to remain controversial. Our approach has been to offer surgery to mitigate the risk of infection and possible malignancy. All patients routinely undergo a CT scan of the chest postnatally and once the diagnosis is confirmed, minimal access surgery is offered. Our anesthetists provide single-lung ventilation to enhance the operative view. We conducted a retrospective review over a 10-year period, during which 91 patients were prenatally suspected to have a cystic lung lesion...
October 10, 2016: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27718493/diagnostic-accuracy-of-fetal-scalp-lactate-for-intrapartum-acidosis-compared-with-scalp-ph
#12
Jara Pascual Mancho, Sabina Marti Gamboa, Olga Redrado Gimenez, Raquel Crespo Esteras, Belen Rodriguez Solanilla, Sergio Castan Mateo
OBJECTIVE: To determine the diagnostic accuracy of fetal scalp lactate sampling (FSLS) and to establish an optimal cut-off value for intrapartum acidosis compared with fetal scalp pH. METHODS: A 20-month retrospective cohort study was conducted of all neonates delivered in our institution for whom fetal scalp blood sampling (FSBS) was performed, matching their intrapartum gasometry to their cord gasometry at delivery (n=243). The time taken from the performance of scalp blood sampling to arterial umbilical cord gas acquisition was 45 min at most...
October 8, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27670964/biodegradable-polydioxanone-stent-as-a-new-treatment-strategy-for-tracheal-stenosis-in-a-rabbit-model
#13
Insu Kawahara, Shigeru Ono, Kosaku Maeda
PURPOSE: Congenital tracheal stenosis (CTS) is a rare condition and difficult to treat. Slide tracheoplasty has unsatisfactory outcomes for severe neonatal symptomatic CTS. This study evaluated the use of biodegradable polydioxanone stents (BD stent) in a rabbit model of CTS. METHODS: Tracheal stenosis was induced in female Japanese white rabbits, 9-10weeks old, by direct scraping of the tracheal mucosa with a nylon brush following transverse incision of the trachea (control group, n=4)...
September 15, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27650526/analysis-of-the-characteristics-and-management-of-critical-values-in-a-newborn-tertiary-center-in-china
#14
Zheng-Li Wang, Li-Zhong Du, Yi-Yu Chen, Lu-Quan Li, Qi Lu, Ying Liu, Lu-Ying Cao, Yu He, Jia-Lin Yu
BACKGROUND: Critical value reporting has been widely adopted by hospitals throughout the world, but there were few reports about neonatal critical values. This study aimed to analyze characteristics of the neonatal critical values considered at our center and to provide information on improving neonatal intensive care. METHODS: A retrospective study of critical values at a newborn tertiary center in China was conducted to assess neonatal critical values according to test, distribution, reporting time, patient outcome and the impact to the therapy...
September 20, 2016: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/27579200/a-case-of-the-tof-with-apv-complicated-with-polyhydramnios-and-severe-bronchomalacia
#15
Ali Seven, Emine Esin Yalinbas, Rahmi Ozdemir
Absent pulmonary valve syndrome (APVS) is a rare congenital heart disease with severe pulmonary insufficiency, characterized with aneurysmal dilation in the pulmonary artery and one or both of its branches. We presented a rare case with APVS and literature review in this letter. Prenatal USG examination of the fetus at the 26th week of gestation revealed severe polyhydramnios, dilatation at right ventricle, and abnormal appearance of the heart. At the 31st gestational week, the baby was born with cesarean section...
2016: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27578120/influence-of-gestational-age-and-birth-weight-in%C3%A2-neonatal-cholesterol-response-to-total-parenteral-nutrition
#16
T Hang Nghiem-Rao, Allison F Dahlgren, Deepti Kalluri, Yumei Cao, Pippa M Simpson, Shailendra B Patel
BACKGROUND: Premature and critically ill infants receiving total parenteral nutrition (TPN) are at risk for dyslipidemia, and altered cholesterol levels in early life may contribute to later cardiovascular risk. Data regarding plasma cholesterol response to TPN in young infants are lacking. OBJECTIVE: To determine the changes in plasma cholesterol levels during the first week of life in infants receiving TPN and a comparison group of infants who did not receive TPN during routine care...
July 2016: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/27571121/neonatal-cyanosis-due-to-hemoglobin-variant-hb-f-sarajevo
#17
Jana Lozar-Krivec, Maja Stepic, Tinka Hovnik, Mladen Krsnik, Darja Paro-Panjan
Neonatal cyanosis is rarely due to hemoglobin variants with low oxygen affinity. We describe the clinical course and results of molecular genetic analysis of a boy who presented after birth with severe cyanosis. Arterial blood-gas analysis demonstrated a pronounced shift of the oxygen-hemoglobin dissociation curve to the right and molecular genetic analysis revealed a γ-globin variant, Hb F-Sarajevo. The patient presented is the second reported case of neonatal cyanosis due to this mutation, which was first described in 2012 by Zimmermann-Baer and coauthors...
October 2016: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/27552216/determinants-of-carboxyhemoglobin-levels-and-relationship-with-sepsis-in-a-retrospective-cohort-of-preterm-neonates
#18
Andrew J McArdle, James Webbe, Kathleen Sim, Graham Parrish, Clive Hoggart, Yifei Wang, J Simon Kroll, Sunit Godambe, Aubrey J Cunnington
Carboxyhemoglobin levels in blood reflect endogenous carbon monoxide production and are often measured during routine blood gas analysis. Endogenous carbon monoxide production has been reported to be increased during sepsis, but carboxyhemoglobin levels have not been thoroughly evaluated as a biomarker of sepsis. We sought to determine whether carboxyhemoglobin levels were elevated during sepsis in a high risk population of premature neonates. We conducted a retrospective cohort study of 30 infants in two neonatal intensive care units using electronic medical and laboratory records...
2016: PloS One
https://www.readbyqxmd.com/read/27495887/routine-measurements-of-cord-arterial-blood-lactate-levels-in-infants-delivering-at-term-and-prediction-of-neonatal-outcome
#19
S Revathy Natesan
OBJECTIVE: Our purpose was to evaluate the relationship between umbilical cord arterial blood lactate levels with acid base balance to the mode of delivery and short-term neonatal outcome in a large multiracial population delivering at term in University of Malaya Medical Centre. MATERIALS AND METHODS: Two thousand two hundred and twelve patients of more than 37 weeks of gestation with singleton, liveborn infants with no major anomalies delivering between January 2013 to December 2013 were analysed...
June 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/27474088/-the-practice-of-neonatal-umbilical-blood-gas-analysis-in-the-alsace-regional-french-perinatal-network
#20
F Kellenberger, C Y Akladios, N Sananes, A Gaudineau, B Langer
OBJECTIVE: The assessment of neonatal well-being is paramount in delivery rooms. For that purpose, it is recommended in France to carry out a systematic neonatal umbilical cord blood gas analysis. The aim of this study is to evaluate how umbilical cord blood gas sampling is realised, analysed and interpreted by midwives in a French regional perinatal network. MATERIALS AND METHODS: We conducted a survey focused on randomly selected midwives partitioning in different maternities that constitute the "Alsace" regional perinatal network...
July 26, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
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