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H Svitlyk, M Harbar, V Salo, O Kapustynskyy, Y Svitlyk
Objective -to identify the role of occupational hazards (OH) as a risk factor of onset and unfavorable outcome of coronary artery disease (CAD). Retrospective study included analysis of 307 case reports of CAD patients, including 59 patients with long term history of OH exposure. Prospective study included observation of 244 STEMI patients during their in-patient treatment, including 113 patients with prior exposure to OH. OH were demonstrated to contribute to the risk of CAD, and to be directly involved in atherosclerotic coronary artery (CA) injury, its role being equal to that of the classical risk factors, such as arterial hypertension (AH), dyslipidemia, and diabetes mellitus (DM)...
February 2018: Georgian Medical News
Taysir S Garadah, Khalid Bin Thani, Leena Sulibech, Ahmed A Jaradat, Mohamed E Al Alawi, Haytham Amin
Background: Risk factors and short-term mortality in patients presented with Acute Coronary Syndrome (ACS) in Bahrain has not been evaluated before. Aim: In this prospective observational study, we aim to determine the clinical risk profiles of patients with ACS in Bahrain and describe the incidence, pattern of presentation and predictors of in-hospital clinical outcomes after admission. Methods: Patients with ACS were prospectively enrolled over a 12 month period...
2018: Open Cardiovascular Medicine Journal
Paul Michael Haller, Bernhard Jäger, Serdar Farhan, Günter Christ, Wolfgang Schreiber, Franz Weidinger, Thomas Stefenelli, Georg Delle-Karth, Alfred Kaff, Gerald Maurer, Kurt Huber
BACKGROUND AND AIM: Our senescent society includes a growing number of elderly people suffering from ST-elevation myocardial infarction (STEMI); however, exactly this population is often underrepresented in randomized trials. Hence, our aim was to investigate the influence of age on patient characteristics, as well as short- and long-term outcome in the Vienna STEMI registry. METHODS: We included all patients of the Vienna STEMI registry (2003-2009). Patients were stratified into age cohorts (≤45, 46-59, 60-79 and ≥80 years, respectively)...
August 23, 2017: Wiener Klinische Wochenschrift
Ömer Şen, Samir Allahverdiyev, Mustafa Topuz, Ahmet Oytun Baykan, Fahrettin Oz, Mevlut Koç
BACKGROUND: Due to ischaemic time delays from the chest pain occurrence in acute ST elevation myocardial infarction (STEMI), prompt recruitment collaterals (PRCCs) to infarct-related artery (IRA) are the major protective structures during this period. AIM: We aimed to investigate the clinical significance and determinants of PRCCs in acute STEMI patients. METHODS: A total of 1375 consecutive acute STEMI patients were prospectively enrolled in the study...
2017: Kardiologia Polska
Idan Roifman, Nilesh Ghugre, Mohammad I Zia, Michael E Farkouh, Anna Zavodni, Graham A Wright, Kim A Connelly
BACKGROUND: Diabetes mellitus (DM) is estimated to become the 7th leading cause of death by 2030. Right ventricular dysfunction (RVD) complicating ST elevation myocardial infarction (STEMI) is independently associated with a higher mortality; however the relationship between DM and RVD is currently unknown. The purpose of this study was to determine whether DM is an independent predictor for the presence of right ventricular dysfunction (RVD) post STEMI. METHODS: 106 patients post primary PCI for STEMI were enrolled in the study...
February 18, 2016: Cardiovascular Diabetology
Juliana C Sebben, Daniel R Pinto Ribeiro, Renato D Lopes, Robert de Winter, Ralf Harskamp, Eduardo Cambruzzi, Marcia Moura Schmidt, Eduarda Schutz Martinelli, Carlos A Gottschall, Alexandre S Quadros
BACKGROUND: Although diabetes mellitus (DM) is a predictor of poor outcomes in patients with ST-segment elevation myocardial infarction (STEMI), few studies have analyzed the impact of DM on the constituency of coronary thrombi. OBJECTIVES: Comparing morphologic and histopathologic aspects of coronary thrombi in STEMI patients with and without DM who underwent primary percutaneous coronary intervention. METHODS: All consecutive patients with STEMI admitted to our institution between April 2010 and December 2012 (n = 1,548) were considered for inclusion...
February 2016: American Heart Journal
Ana Novakovic, Ejub Zukic, Belma Gazibera, Refet Gojak
INTRODUCTION: The occurrence of hyperglycemia in non-diabetics during development of acute coronary ischemia (ACI) indicates latent glucose metabolism disorder, or is a case of newly discovered diabetes mellitus (DM) as a result of stress. Acute coronary syndrome refers to a group of clinical syndromes caused by a sudden circulatory disorder in coronary arteries, resulting in the corresponding myocardial ischemia. It covers range from unstable angina and myocardial infarction (MI) without Q wave in the electrocardiogram finding (NSTEMI) up to myocardial infarction with Q wave in the electrocardiogram finding (STEMI)...
August 2015: Medical Archives
Hou Tee Lu, Rusli Bin Nordin
BACKGROUND: The National Cardiovascular Disease (NCVD) Database Registry represents one of the first prospective, multi-center registries to treat and prevent coronary artery disease (CAD) in Malaysia. Since ethnicity is an important consideration in the occurrence of acute coronary syndrome (ACS) globally, therefore, we aimed to identify the role of ethnicity in the occurrence of ACS among high-risk groups in the Malaysian population. METHODS: The NCVD involves more than 15 Ministry of Health (MOH) hospitals nationwide, universities and the National Heart Institute and enrolls patients presenting with ACS [ST-elevation myocardial infarction (STEMI), non-ST elevation myocardial infarction (NSTEMI) and unstable angina (UA)]...
2013: BMC Cardiovascular Disorders
Mushabab A Al-Murayeh, Adel A Al-Masswary, Mohamed D Dardir, Mohamed S Moselhy, Ali A Youssef
OBJECTIVES: To investigate acute coronary syndromes (ACS) in the young Saudi population in Aseer Region, southwestern Saudi Arabia. MATERIALS AND METHODS: We retrospectively reviewed our database between January 2006 and May 2009, 924 patients were diagnosed to have ACS. Among them 107 patients (11.6%) met our definition of young [66 (61.7%) male < 45 years, and 41 (38.3%) female < 55 years]. We compared this study population to a control group of 50 elderly patients consecutively enrolled in a contemporary period...
July 2012: Journal of the Saudi Heart Association
Jawad Al-Lawati, Kadhim Sulaiman, Prashanth Panduranga
OBJECTIVES: This study aimed to evaluate the epidemiology and coronary risk factors of acute coronary syndrome (ACS) in Oman. METHODS: Data were collected through a prospective, multinational, multicentre survey of consecutive patients, hospitalised over a 5-month period in 2007 with a diagnosis of ACS, in Yemen and five Arabian Gulf countries (Oman, Bahrain, Kuwait, Qatar, United Arab Emirates). Here we present data of Omani patients aged ≥20 years who received a provisional diagnosis of ACS and were consequently admitted to 14 different hospitals...
February 2013: Sultan Qaboos University Medical Journal
Mina M Benjamin, Giovanni Filardo, Michael S Donsky, Jeffrey M Schussler
BACKGROUND: Dual anti-platelet therapy including clopidogrel or prasugrel is standard of care for patients receiving stents. Prasugrel has quicker onset so it can be loaded later than clopidogrel with greater efficacy. However, prasugrel is much more expensive than clopidogrel. OBJECTIVES: To describe the incidence of 30-day death from cardiovascular causes, myocardial infarction, unstable angina requiring intervention, and minor and major bleeding in patients loaded with 60 mg of prasugrel prior to percutaneous coronary intervention (PCI) and then continued on 75 mg of clopidogrel daily after the procedure...
February 2013: Journal of Interventional Cardiology
Mariusz Gąsior, Damian Pres, Marek Gierlotka, Michał Hawranek, Grzegorz Słonka, Andrzej Lekston, Paweł Buszman, Zbigniew Kalarus, Marian Zembala, Lech Poloński
BACKGROUND: Cardiogenic shock (CS) affects the prognosis in patients with myocardial infarction (MI). An additional factor affecting the prognosis is diabetes mellitus (DM). AIM: To evaluate the impact of DM on in-hospital and long-term mortality in patients with MI complicated by CS, who were included in the Polish Registry of Acute Coronary Syndromes (PL-ACS). We also sought to demonstrate a relationship between treatment method and mortality in this group. METHODS: 71,290 consecutive patients with non-ST elevation MI (NSTEMI; 33,392) and ST elevation MI (STEMI; 37,898) were included in the PL-ACS register...
2012: Kardiologia Polska
Taysir S Garadah, Salah Kassab, Qasim M Al-Shboul, Abdulhai Alawadi
UNLABELLED: Recent studies indicated a high prevalence of hyperglycemia in non-diabetic patients presenting with acute coronary syndrome (ACS). However, the threshold of admission glucose (AG) as a predictor of adverse events in ACS is unclear. OBJECTIVE: The aim of this study was to assess the threshold of admission glucose (AG) as a predictor of adverse events including Major Acute Cardiac Events (MACE) and mortality, during the first week of admitting patients presenting with ACS...
2009: Clinical Medicine. Cardiology
Nazif Aygül, Kurtuluş Ozdemir, Adnan Abaci, Meryem Ulkü Aygül, Mehmet Akif Düzenli, Mehmet Akif Vatankulu, Hüseyin Uğur Yazici, Ibrahim Ozdoğru, Ekrem Karakaya
OBJECTIVE: There is not enough available data in our country about the prevalence of risk factors for ST-elevation myocardial infarction (STEMI), which has the highest in-hospital mortality rate within subtypes of acute coronary syndromes. Therefore, in this study, we aimed to evaluate the prevalence of risk factors for STEMI in Central Anatolia, one of the regions with high risk for coronary heart disease (CHD). METHODS: This cross-sectional observational study included 1210 patients (962 men, 248 women) with the diagnosis of STEMI in 3 tertiary-medical centers in 3 cities in Central-Anatolia (Ankara, Konya, and Kayseri)...
February 2009: Anadolu Kardiyoloji Dergisi: AKD, the Anatolian Journal of Cardiology
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