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https://www.readbyqxmd.com/read/28522050/ethical-mutiny-when-the-captain-of-the-ship-is-an-outlier
#1
Sphoorthi Jinna, Jane M Grant-Kels, Jerry Graff
No abstract text is available yet for this article.
June 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28520742/experimental-outgassing-of-toxic-chemicals-to-simulate-the-characteristics-of-hazards-tainting-globally-shipped-products
#2
Lygia Therese Budnik, Nadine Austel, Sabrina Gadau, Stefan Kloth, Jens Schubert, Harald Jungnickel, Andreas Luch
Ambient monitoring analyses may identify potential new public health hazards such as residual levels of fumigants and industrial chemicals off gassing from products and goods shipped globally. We analyzed container air with gas chromatography coupled to mass spectrometry (TD-2D-GC-MS/FPD) and assessed whether the concentration of the volatiles benzene and 1,2-dichloroethane exceeded recommended exposure limits (REL). Products were taken from transport containers and analyzed for outgassing of volatiles. Furthermore, experimental outgassing was performed on packaging materials and textiles, to simulate the hazards tainting from globally shipped goods...
2017: PloS One
https://www.readbyqxmd.com/read/28514206/first-in-human-pet-ct-imaging-of-metastatic-neuroendocrine-neoplasms-with-cyclotron-produced-44-sc-dotatoc-a-proof-of-concept-study
#3
Aviral Singh, Nicholas P van der Meulen, Cristina Müller, Ingo Klette, Harshad R Kulkarni, Andreas Türler, Roger Schibli, Richard P Baum
(44)Sc is a promising positron emission tomography (PET) radionuclide (T1/2 = 4.04 hours, Eβ+average = 632 keV) and can be made available, using a cyclotron production route, in substantial quantities as a highly pure product. Herein, the authors report on a first-in-human PET/CT study using (44)Sc-DOTATOC prepared with cyclotron-produced (44)Sc. The production of (44)Sc was carried out through the (44)Ca(p,n)(44)Sc nuclear reaction at Paul Scherrer Institut, Switzerland. After separation, (44)Sc was shipped to Zentralklinik Bad Berka, Germany, where radiolabeling was performed, yielding radiochemically pure (44)Sc-DOTATOC...
May 2017: Cancer Biotherapy & Radiopharmaceuticals
https://www.readbyqxmd.com/read/28508714/recommendations-for-clinical-biomarker-specimen-preservation-and-stability-assessments
#4
Naveen Dakappagari, Hui Zhang, Laurie Stephen, Lakshmi Amaravadi, Masood U Khan
With the wide use of biomarkers to enable critical drug-development decisions, there is a growing concern from scientific community on the need for a 'standardized process' for ensuring biomarker specimen stability and hence, a strong desire to share best practices on preserving the integrity of biomarker specimens in clinical trials and the design of studies to evaluate analyte stability. By leveraging representative industry experience, we have attempted to provide an overview of critical aspects of biomarker specimen stability commonly encountered during clinical development, including: planning of clinical sample collection procedures, clinical site training, selection of sample preservation buffers, shipping logistics, fit-for-purpose stability assessments in the analytical laboratory and presentation of case studies covering widely utilized biomarker specimen types...
May 15, 2017: Bioanalysis
https://www.readbyqxmd.com/read/28508711/surface-sensing-and-stress-signalling-in-ulva-and-fouling-diatoms-potential-targets-for-antifouling-a-review
#5
Stephanie E M Thompson, Juliet C Coates
Understanding the underlying signalling pathways that enable fouling algae to sense and respond to surfaces is essential in the design of environmentally friendly coatings. Both the green alga Ulva and diverse diatoms are important ecologically and economically as they are persistent biofoulers. Ulva spores exhibit rapid secretion, allowing them to adhere quickly and permanently to a ship, whilst diatoms secrete an abundance of extracellular polymeric substances (EPS), which are highly adaptable to different environmental conditions...
May 2017: Biofouling
https://www.readbyqxmd.com/read/28508710/transported-biofilms-and-their-influence-on-subsequent-macrofouling-colonization
#6
L Holly Sweat, Geoffrey W Swain, Kelli Z Hunsucker, Kevin B Johnson
Biofilm organisms such as diatoms are potential regulators of global macrofouling dispersal because they ubiquitously colonize submerged surfaces, resist antifouling efforts and frequently alter larval recruitment. Although ships continually deliver biofilms to foreign ports, it is unclear how transport shapes biofilm microbial structure and subsequent macrofouling colonization. This study demonstrates that different ship hull coatings and transport methods change diatom assemblage composition in transported coastal marine biofilms...
May 2017: Biofouling
https://www.readbyqxmd.com/read/28506499/determination-of-butyltins-phenyltins-and-octyltins-in-foods-with-preservation-of-their-moieties-a-critical-review-on-analytical-methods
#7
REVIEW
Stephen W C Chung, Andy H T Wu
Tributyltin and triphenyltin have been extensively applied in anti-fouling paints since the 1960s. Hence, organotin compounds (OTCs), especially butyltins and phenyltins, in seafood has been of concern for decades. Even though the "International Convention on the Control of Harmful Anti-Fouling Systems on Ships, 2001" entered into force internationally in 2008 and prohibited the use of OTCs in anti-fouling paints used on ships, the analysis of OTCs in seafood was not commonly included in routine monitoring programmes...
May 8, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28502453/petroleum-hydrocarbon-toxicity-to-corals-a-review
#8
REVIEW
Nicholas R Turner, D Abigail Renegar
The proximity of coral reefs to coastal urban areas and shipping lanes predisposes corals to petroleum pollution from multiple sources. Previous research has evaluated petroleum toxicity to coral using a variety of methodology, including monitoring effects of acute and chronic spills, in situ exposures, and ex situ exposures with both adult and larval stage corals. Variability in toxicant, bioassay conditions, species and other methodological disparities between studies prevents comprehensive conclusions regarding the toxicity of hydrocarbons to corals...
May 10, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28498123/comparison-of-phosphorus-fraction-distribution-and-influencing-factors-of-suspended-and-surface-sediments-in-the-tiaoxi-watershed-china
#9
Hongmeng Ye, Xuyin Yuan, Lei Han, Heng Yin, Jing Jin
Suspended and surface sediments from the Tiaoxi watershed, fed by the Xitiaoxi and Dongtiaoxi rivers, were analyzed for total phosphorus (TP) and the inorganic P fractions of loosely adsorbed P that were extractable with NH4Cl (NH4Cl-P), reductant P (BD-P), metal oxide-bound P extractable with NaOH (NaOH-P), and calcium-bound, HCl-extractable P (HCl-P), while other physicochemical compositions were also determined. The spatial variations of P fractions in these sediments were investigated, and the major factors influencing the various fractions were explored by multivariate statistics...
May 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28495723/shipping-iron-around-in-small-packages
#10
EDITORIAL
Jake Yeston
No abstract text is available yet for this article.
May 12, 2017: Science
https://www.readbyqxmd.com/read/28495477/quantification-of-saxitoxin-in-human-blood-by-elisa
#11
Rebekah E Wharton, Melanie C Feyereisen, Andrea L Gonzalez, Nicole L Abbott, Elizabeth I Hamelin, Rudolph C Johnson
Saxitoxin (STX) is a potent marine toxin that causes paralytic shellfish poisoning (PSP) which can result in significant morbidity and mortality in humans. Low lethal doses, rapid onset of PSP symptoms, and brief STX half-life in vivo require sensitive and rapid diagnostic techniques to monitor human exposures. Our laboratory has validated an enzyme-linked immunosorbent assay (ELISA) for quantitative detection of STX from 0.020 to 0.80 ng/mL in human whole blood and from 0.06 to 2.0 ng/mL in dried human blood which is simple, sensitive, rapid, and cost-effective...
May 7, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28495433/ventricular-and-supraventricular-ectopy-in-subjects-with-early-repolarization
#12
Teresa Trenkwalder, Ryan King, Bernhard M Kaess, Christian Hengstenberg, Heribert Schunkert, Till Ittermann, Stephan B Felix, Mathias Busch, Marcus Dörr, Wibke Reinhard
Early repolarization (ER) is a common electrocardiographic (ECG) finding that is associated with an increased risk of idiopathic ventricular fibrillation and sudden cardiac death. This study investigated whether the presence of ER is a predictor of ventricular and supraventricular ectopy as a marker for electrical instability. Standard 12-lead electrocardiograms of the first follow-up in the population-based Study of Health in Pomerania (SHIP-1) (n = 3,300, age 20 to 79 years) were analyzed to identify subjects with an ER pattern...
April 12, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28489902/disturbance-of-a-rare-seabird-by-ship-based-tourism-in-a-marine-protected-area
#13
Timothy K Marcella, Scott M Gende, Daniel D Roby, Arthur Allignol
Managers of marine protected areas (MPAs) must often seek ways to allow for visitation while minimizing impacts to the resources they are intended to protect. Using shipboard observers, we quantified the "zone of disturbance" for Kittlitz's and marbled murrelets (Brachyramphus brevirostris and B. marmoratus) exposed to large cruise ships traveling through Glacier Bay National Park, one of the largest MPAs in North America. In the upper reaches of Glacier Bay, where Kittlitz's murrelets predominated, binary logistic regression models predicted that 61% of all murrelets within 850 m perpendicular distance of a cruise ship were disturbed (defined as flushing or diving), whereas in the lower reaches, where marbled murrelets predominated, this percentage increased to 72%...
2017: PloS One
https://www.readbyqxmd.com/read/28484806/chemical-characterisation-of-the-whole-plant-cell-wall-of-archaeological-wood-an-integrated-approach
#14
Luca Zoia, Diego Tamburini, Marco Orlandi, Jeannette Jacqueline Łucejko, Anika Salanti, Eeva-Liisa Tolppa, Francesca Modugno, Maria Perla Colombini
Wood artefacts undergo complex alteration and degradation during ageing, and gaining information on the chemical composition of wood in archaeological artefacts is fundamental to plan conservation strategies. In this work, an integrated analytical approach based on innovative NMR spectroscopy procedures, gel permeation chromatography and analytical pyrolysis coupled with gas chromatography/mass spectrometry (Py-GC-MS) was applied for the first time on archaeological wood from the Oseberg collection (Norway), in order to evaluate the chemical state of preservation of the wood components, without separating them...
May 8, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28484040/content-analysis-of-age-verification-purchase-and-delivery-methods-of-internet-e-cigarette-vendors-2013-and-2014
#15
Rebecca S Williams, Jason Derrick, Aliza Kate Liebman, Kevin LaFleur, Kurt M Ribisl
OBJECTIVE: Identify the population of internet e-cigarette vendors (IEVs) and conduct content analyses of their age verification, purchase and delivery methods in 2013 and 2014. METHODS: We used multiple sources to identify IEV websites, primarily complex search algorithms scanning more than 180 million websites. In 2013, we manually screened 32 446 websites, identifying 980 IEVs, selecting the 281 most popular for content analysis. This methodology yielded 31 239 websites for screening in 2014, identifying 3096 IEVs, with 283 selected for content analysis...
May 8, 2017: Tobacco Control
https://www.readbyqxmd.com/read/28481548/cross-sectional-association-of-salivary-proteins-with-age-sex-body-mass-index-smoking-and-education
#16
Annette Murr, Christiane Pink, Elke Hammer, Stephan Michalik, Vishnu Mukund Dhople, Birte Holtfreter, Uwe Völker, Thomas Kocher, Manuela Gesell Salazar
Whole saliva is gaining more and more attention as a diagnostic tool to study disease-specific changes in human subjects. Prior to the actual disease-related analyses, it is important to understand the influence of various demographic variables and coupled phenotypes on salivary protein signatures. In a cross-sectional approach, we analyzed the influence of age, sex, body mass index (BMI), smoking, and education on salivary protein signatures in whole saliva samples of 187 individuals. Subjects were randomly selected from the population-based Study of Health in Pomerania (SHIP-Trend)...
May 8, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28481195/prevalence-of-fatty-liver-disease-and-hepatic-iron-overload-in-a-northeastern-german-population-by-using-quantitative-mr-imaging
#17
Jens-Peter Kühn, Peter Meffert, Christian Heske, Marie-Luise Kromrey, Carsten O Schmidt, Birger Mensel, Henry Völzke, Markus M Lerch, Diego Hernando, Julia Mayerle, Scott B Reeder
Purpose To quantify liver fat and liver iron content by measurement of confounder-corrected proton density fat fraction (PDFF) and R2* and to identify clinical associations for fatty liver disease and liver iron overload and their prevalence in a large-scale population-based study. Materials and Methods From 2008 to 2013, 2561 white participants (1336 women; median age, 52 years; 25th and 75th quartiles, 42 and 62 years) were prospectively recruited to the Study of Health in Pomerania (SHIP). Complex chemical shift-encoded magnetic resonance (MR) examination of the liver was performed, from which PDFF and R2* were assessed...
May 5, 2017: Radiology
https://www.readbyqxmd.com/read/28480512/regulation-of-immune-cell-signaling-by-ship1-a-phosphatase-scaffold-protein-and-potential-therapeutic-target
#18
REVIEW
Samantha D Pauls, Aaron J Marshall
The phosphoinositide phosphatase SHIP is a critical regulator of immune cell activation. Despite considerable study, the mechanisms controlling SHIP activity to ensure balanced cell activation remain incompletely understood. SHIP dampens B-cell antigen receptor (BCR) signaling in part through its association with the inhibitory co-receptor FcγRIIB, and serves as an effector for other inhibitory receptors in various immune cell types. The established paradigm emphasizes SHIP's inhibitory receptor-dependent function in regulating phosphoinositide 3-kinase (PI3K) signaling by dephosphorylating the phosphoinositide PI(3,4,5)P3 ; however, substantial evidence indicates that SHIP can be activated independently of inhibitory receptors and can function as an intrinsic brake on activation signaling...
May 7, 2017: European Journal of Immunology
https://www.readbyqxmd.com/read/28480490/impact-of-shipping-emissions-on-ozone-levels-over-europe-assessing-the-relative-importance-of-the-standard-nomenclature-for-air-pollution-snap-categories
#19
Efthimios Tagaris, Ioannis Stergiou, Rafaella-Eleni P Sotiropoulou
The impact of shipping emissions on ozone mixing ratio over Europe is assessed for July 2006 using the Community Multiscale Air Quality modeling system and the Netherlands Organization for Applied Scientific Research anthropogenic emission inventory. Results suggest that ship-induced ozone contribution to the total surface ozone exceeds 5% over the sea and near the coastline, while an increase up to 5% is simulated over a large portion of the European land. The largest impact (i.e., an increase up to 30%) is simulated over the Mediterranean Sea...
May 8, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28463067/study-on-jet-aeration-oxidation-of-magnesium-sulfite-from-magnesium-based-exhaust-gas-cleaning-system
#20
Lin Guo, Xiaojia Tang, Hui Wang, Tie Li, Weifeng Liu, Quan Liu, Yimin Zhu
Oxidation of magnesium sulfite in washing water is essential for the treatment of by-product of shipboard magnesium-based exhaust gas cleaning systems. The purpose of this study is to obtain a highly efficient magnesium sulfite oxidation technology by using the jet aeration process. Response surface methodology and central composite design were used to investigate the effects of major variables on oxidation of magnesium sulfite and optimize the oxidation conditions. The predictions of the two response functions agree well with the experimental data...
May 11, 2017: Environmental Technology
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