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https://www.readbyqxmd.com/read/28211332/3-3-dichlorobiphenyl-non-aroclor-pcb-11-as-a-marker-of-non-legacy-pcb-contamination-in-marine-species-comparison-between-antarctic-and-mediterranean-bivalves
#1
Sarah Pizzini, Chiara Sbicego, Fabiana Corami, Marco Grotti, Emanuele Magi, Tiziano Bonato, Giulio Cozzi, Carlo Barbante, Rossano Piazza
In this study the accumulation of the 3,3'-dichlorobiphenyl (PCB-11) in monitoring organisms from the Antarctic and Mediterranean coastal environments has been investigated. This lesser-known PCB congener, unrelated to the industrial use of commercial mixtures, continues to be generated and released into the environment mainly as an unintentional by-product of pigment manufacturing. Specimens of the filter-feeders Adamussium colbecki from Terra Nova Bay and of Mytilus galloprovincialis and Ruditapes philippinarum from the north-western Adriatic coasts were collected and analyzed for PCB-11 by Gas Chromatography coupled both to Low-Resolution and High-Resolution Mass Spectrometry (LRMS, HRMS)...
February 6, 2017: Chemosphere
https://www.readbyqxmd.com/read/28203645/saharan-dust-detection-using-multi-sensor-satellite-measurements
#2
Sriharsha Madhavan, John J Qu, X Hao
Contemporary scientists have vested interest in trying to understand the climatology of the North Atlantic Basin since this region is considered as the genesis for hurricane formation that eventually get shipped to the tropical Atlantic region and the Caribbean. The effects of atmospheric water cycle and the climate of West Africa and the Atlantic basin are hugely impacted by the radiative forcing of Saharan dust. The focus area in this paper would be to improve the dust detection schemes by employing the use of multi sensor measurements in the thermal emissive wavelengths using legacy sensors such as Terra (T) and Aqua (A) MODerate-resolution Imaging Spectroradiometer (MODIS), fusing with Ozone Monitoring Instrument (OMI)...
February 2017: Heliyon
https://www.readbyqxmd.com/read/28202279/potential-bioavailability-assessment-source-apportionment-and-ecological-risk-of-heavy-metals-in-the-sediment-of-brisbane-river-estuary-australia
#3
Godfred Odame Duodu, Ashantha Goonetilleke, Godwin A Ayoko
A weak acid extraction was used to mobilize the loosely bound metals in estuary sediment samples. More than 30% of Ag, As, Ca, Cd, Co, Cu, Hg, Mn Ni, Pb and Zn were leached from the sediment showing that these metals are significantly present in the bioavailable form. PCA/APCS identified three sources of the metals, namely: lithogenic accounting for 72%, shipping related contributing 15% and traffic related representing 13% of the total load. Application of pollution index (PI) and modified pollution index (MPI) revealed that the sediment range from unpolluted to heavily polluted while ecological risk index (RI) classifies the sediment as posing low ecological risk modified ecological risk index (MRI) suggests considerable to very high ecological risk...
February 12, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28193634/purified-streptococcus-pneumoniae-endopeptidase-o-pepo-enhances-particle-uptake-by-macrophages-in-a-tlr2-and-mir-155-dependent-manner
#4
Hua Yao, Hong Zhang, Kai Lan, Hong Wang, Yufeng Su, Dagen Li, Zhixin Song, Fang Cui, Yibing Yin, Xuemei Zhang
Insights into the host-microbial virulence factors interaction, especially the immune-signaling mechanisms, could provide novel prevention and treatment options for pneumococcal diseases. Streptococcus pneumoniae endopeptidase O (PepO) is a newly discovered and ubiquitously expressed pneumococcal virulence protein. A PepO-mutant strain showed impaired adherence to and invasion of host cells compared with their isogenic wild-type strains. It is still unknown whether PepO is involved in host defense response against pneumococcal infection...
February 13, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28191786/quantifying-the-potential-pathways-and-locations-of-rift-valley-fever-virus-entry-into-the-united-states
#5
A J Golnar, R C Kading, G L Hamer
The global invasion of West Nile virus, chikungunya virus and Zika virus in the past two decades suggests an increasing rate of mosquito-borne virus (arbovirus) dispersal. Rift Valley fever virus (RVFV) is an arbovirus identified as a high-consequence threat to the United States (USA) because of the severe economic and health consequences associated with disease. Numerous studies demonstrate that the USA is receptive to RVFV transmission based on the widespread presence of competent mosquito species and vertebrate species...
February 12, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/28190377/collaborative-approach-to-the-creation-of-an-arteriovenous-fistula-on-a-us-navy-hospital-ship
#6
Kimberly A Thompson, Amrish Krishnan, Charles Stehman, Steven Hanling, Kevin Casey
Early creation of arteriovenous fistulas (AVFs) decreases morbidity and mortality in patients with end-stage renal disease and is the standard of care in the United States. However, this procedure is frequently not accessible in low- and middle-income countries (LMICs). We present the first reported case of successful AVF creation as part of a humanitarian assistance mission. The patient was a 51-year-old male with diabetes, hypertension, and end-stage renal disease on hemodialysis via a temporary dialysis catheter...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28187967/an-investigation-of-the-space-distribution-of-ulva-microscopic-propagules-and-ship-based-experiment-of-mitigation-using-modified-clay
#7
Jing Li, Xiuxian Song, Yue Zhang, Jun Pan, Zhiming Yu
Previous studies suggested that the removal of Ulva microscopic propagules (UMP) from cradle water might restrict the formation and expansion of green tides in the Yellow Sea, China. In this study, the distribution characteristics of UMP in the southern Yellow Sea was investigated, and then a flocculation experiment of UMP using modified clay (MC) was conducted at a selected station of the research cruise. The results indicated that the distribution of green algae thalli is one of the main factors that directly influence UMP distribution...
February 7, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28184381/a-multicenter-longitudinal-interventional-double-blind-randomized-clinical-trial-in-hematopoietic-cell-transplant-recipients-residing-in-remote-areas-lessons-learned-from-the-late-cytomegalovirus-prevention-trial
#8
Louise E Kimball, Terry Stevens-Ayers, Margaret L Green, Hu Xie, Mary E D Flowers, Keith R Jerome, Renee LeBlanc, Christi Dahlgren, W Garrett Nichols, Roy F Chemaly, G Papanicolaou, Michael Boeckh
PURPOSE: The logistics of conducting double-blinded phase III clinical trials with participants residing in remote locations are complex. Here we describe the implementation of an interventional trial for the prevention of late cytomegalovirus (CMV) disease in hematopoietic cell transplantation (HCT) subjects in a long-term follow-up environment. METHODS: A total of 184 subjects at risk for late CMV disease surviving 80 days following allogeneic HCT were randomized to receive six months of valganciclovir or placebo...
December 15, 2016: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/28182851/visualizations-for-genetic-assignment-analyses-using-the-saddlepoint-approximation-method
#9
L F McMillan, R M Fewster
We propose a method for visualizing genetic assignment data by characterizing the distribution of genetic profiles for each candidate source population. This method enhances the assignment method of Rannala and Mountain (1997) by calculating appropriate graph positions for individuals for which some genetic data are missing. An individual with missing data is positioned in the distributions of genetic profiles for a population according to its estimated quantile based on its available data. The quantiles of the genetic profile distribution for each population are calculated by approximating the cumulative distribution function (CDF) using the saddlepoint method, and then inverting the CDF to get the quantile function...
February 9, 2017: Biometrics
https://www.readbyqxmd.com/read/28182678/an-improved-cs-lssvm-algorithm-based-fault-pattern-recognition-of-ship-power-equipments
#10
Yifei Yang, Minjia Tan, Yuewei Dai
A ship power equipments' fault monitoring signal usually provides few samples and the data's feature is non-linear in practical situation. This paper adopts the method of the least squares support vector machine (LSSVM) to deal with the problem of fault pattern identification in the case of small sample data. Meanwhile, in order to avoid involving a local extremum and poor convergence precision which are induced by optimizing the kernel function parameter and penalty factor of LSSVM, an improved Cuckoo Search (CS) algorithm is proposed for the purpose of parameter optimization...
2017: PloS One
https://www.readbyqxmd.com/read/28181929/corneal-endothelial-cell-integrity-in-precut-human-donor-corneas-enhanced-by-autocrine-vasoactive-intestinal-peptide
#11
Shay-Whey M Koh, Timothy Coll, Dante Gloria, Nicholas Sprehe
PURPOSE: To demonstrate that vasoactive intestinal peptide (VIP), a corneal endothelial (CE) cell autocrine factor, maintains the integrity of corneal endothelium in human donor corneoscleral explants precut for endothelial keratoplasty. METHODS: Twelve paired human donor corneoscleral explants used as control versus VIP-treated explants (10 nM, 30 minutes, 37°C) were shipped (4°C) to the Lions Eye Institute for Transplantation and Research for precutting (Moria CBM-ALTK Keratome), shipped back to the laboratory, and cultured in ciliary neurotrophic factor (CNTF, 0...
February 8, 2017: Cornea
https://www.readbyqxmd.com/read/28179537/early-tyrosine-phosphorylation-events-following-adenosine-a2a-receptor-in-human-neutrophils-identification-of-regulated-pathways
#12
Miriam S Giambelluca, Marc Pouliot
Activation of the adenosine 2A receptor (A2AR) elevates intracellular levels of cAMP and acts as a physiologic inhibitor of inflammatory neutrophil functions. In this study, we looked into the impact of A2AR engagement on early phosphorylation events. Neutrophils were stimulated with well-characterized proinflammatory agonists in the absence or presence of an A2AR agonist {3-[4-[2-[ [6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-yl]purin-2-yl]amino] ethyl] phenyl] propanoic acid (CGS 21680)}, PGE2, or a mixture of the compounds RO 20-1724 and forskolin...
February 8, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28175963/curcumin-suppresses-cisplatin-resistance-development-partly-via-modulating-extracellular-vesicle-mediated-transfer-of-meg3-and-mir-214-in-ovarian-cancer
#13
Jing Zhang, Jinyu Liu, Xinyan Xu, Li Li
PURPOSE: To investigate how curcumin alters the extracellular vesicles' (EVs) capability to ship drug resistance in ovarian cancer. METHODS: The EVs from cisplatin-resistant A2780cp cells with curcumin treatment (EVs-CU) or without curcumin treatment (EVs-N) were collected for lncRNA profiling. Curcumin's effect on MEG3 promoter methylation and MEG3 expression were studied by MSP and qRT-PCR, respectively. The regulative effect of MEG3 on miR-214 expression and the functional role of EVs mediated transfer of miR-214 in cisplatin resistance were further investigated...
February 8, 2017: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/28168823/opo-strategies-to-prevent-unintended-use-of-kidneys-exported-for-high-pra-98-cpra-recipients
#14
A S Paramesh, N Neidlinger, M Salvatore, A Smith, A Friedman, W Payne, T Taber, C Wright
Since the advent of the Kidney Allocation System (KAS), matched candidates with high (>98%) panel reactive antibody (hPRA) are given priority over local candidates with lower PRA. This often leads to exporting of kidneys. Data for these kidneys is not detailed on routine reports. Twenty two organ procurement organizations prospectively submitted data from 8/2015 - 7/2016, describing allocation practices of kidneys to hPRA patients and outcomes of these kidneys. 520 out of 6924 procured kidneys were exported for hPRA recipients...
February 6, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28165312/incidence-of-lameness-and-association-of-cause-and-severity-of-lameness-on-the-outcome-for-cattle-on-six-commercial-beef-feedlots
#15
Shane P Terrell, Christopher D Reinhardt, Connie K Larson, Christopher I Vahl, Daniel U Thomson
OBJECTIVE To describe the incidence of specific causes of lameness and the associations of cause and severity of lameness on the outcome for cattle on commercial feedlots. DESIGN Dynamic population longitudinal study. ANIMALS Cattle on 6 commercial feedlots in Kansas and Nebraska during a 12-month period (mean daily population, 243,602 cattle; range, 223,544 to 252,825 cattle). PROCEDURES Feedlot personnel were trained to use a standardized diagnostic algorithm and locomotion score (LMS) system to identify and classify cattle by cause and severity of lameness...
February 15, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28164686/medical-resource-preparation-and-allocation-for-humanitarian-assistance-based-on-module-organization
#16
Min Zhu, Ruxue Chen, Shaobo Zhong, Yangming Qian, Quanyi Huang
BACKGROUND: This research aims to associate the allocation of medical resources with the function of the modular organization and the possible needs for humanitarian assistance missions. METHODS: The overseas humanitarian medical assistance mission, which was sent after a disaster on the hospital ship Peace Ark, part of China's People's Liberation Army (PLA) Navy, was considered as study model. The cases used for clustering and matching sample formation were randomly selected from the existing information related to Peace Ark's mission...
February 2017: Minerva Medica
https://www.readbyqxmd.com/read/28162076/am-i-about-to-start-work-on-a-sinking-ship
#17
Emma Cowen
It is impossible to avoid all the negative headlines about healthcare and, as someone who is about to embark on a career in the NHS, they make my heart sink.
February 6, 2017: Nursing Children and Young People
https://www.readbyqxmd.com/read/28160784/assistive-technology-pricing-in-australia-is-it-efficient-and-equitable
#18
Michael P Summers, George Verikios
Objective To examine available systematically collected evidence regarding prices for assistive technology (AT; e.g. disability aids and equipment) in Australia with other comparable countries. Issues of appropriate AT pricing are coming to the fore as a consequence of efforts to move to consumer-centric purchasing decisions with the National Disability Insurance Scheme (NDIS) and also in the recent aged care reforms.Methods We identified and present three sets of AT price comparisons. Two comparisons were based solely on the lowest prices advertised on the internet, and one comparison examined recommended retail prices...
February 6, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/28159438/reference-intervals-for-serum-sphingosine-1-phosphate-in-the-population-based-study-of-health-in-pomerania
#19
Eileen Moritz, Danilo Wegner, Stefan Groß, Martin Bahls, Marcus Dörr, Stephan B Felix, Till Ittermann, Stefan Oswald, Matthias Nauck, Nele Friedrich, Rainer H Böger, Günter Daum, Edzard Schwedhelm, Bernhard H Rauch
BACKGROUND: The bioactive signaling lipid sphingosine-1-phosphate (S1P) is a potential biomarker for cardiovascular disease (CVD). To date, no reference intervals for S1P have been defined. This study aims to establish a reference range for serum S1P in healthy individuals. METHODS: We determined reference intervals for S1P levels according to gender and age in a sample of 1339 healthy participants of the Study of Health in Pomerania (SHIP)-TREND cohort after exclusion of subjects with CVD, diabetes mellitus, hypertension, metabolic syndrome, elevated liver enzymes, chronic kidney disease stadium III or IV, or body mass index (BMI)>30kg/m(2)...
January 31, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28158270/developmental-time-course-and-effects-of-immunostressors-that-alter-hormone-responsive-behavior-on-microglia-in-the-peripubertal-and-adult-female-mouse-brain
#20
Mary K Holder, Jeffrey D Blaustein
In female mice, the experience of being shipped from the breeder facility or a single injection of the bacterial endotoxin, lipopolysaccharide (LPS), during pubertal development alters the behavioral response to estradiol in adulthood as demonstrated by perturbations of estradiol's effects on sexual behavior, cognitive function, as well as its anxiolytic and anti-depressive properties. Microglia, the primary type of immunocompetent cell within the brain, contribute to brain development and respond to stressors with marked and long-lasting morphological and functional changes...
2017: PloS One
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