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asthma, food allergy, anaphylaxis, rhinitis, drug allergy

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https://www.readbyqxmd.com/read/27475776/parent-reported-prevalence-of-food-allergy-in-mexican-schoolchildren-a-population-based-study
#1
N Ontiveros, E E Valdez-Meza, M J Vergara-Jiménez, A Canizalez-Román, A Borzutzky, F Cabrera-Chávez
BACKGROUND: Food allergy (FA) prevalence is well documented in developed countries and appears to be increasing, but remains unknown in most Latin American countries. We aimed to evaluate on a population basis the parent-reported prevalence of FA and its clinical characteristics in Mexican schoolchildren. METHODS: A validated Spanish version of a structured written questionnaire was administered to parents of schoolchildren aged 5-13 years old from Culiacan, Mexico...
July 27, 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27448446/roles-of-mas-related-g-protein-coupled-receptor-x2-on-mast-cell-mediated-host-defense-pseudoallergic-drug-reactions-and-chronic-inflammatory-diseases
#2
REVIEW
Hariharan Subramanian, Kshitij Gupta, Hydar Ali
Mast cells (MCs), which are granulated tissue-resident cells of hematopoietic lineage, contribute to vascular homeostasis, innate/adaptive immunity, and wound healing. However, MCs are best known for their roles in allergic and inflammatory diseases, such as anaphylaxis, food allergy, rhinitis, itch, urticaria, atopic dermatitis, and asthma. In addition to the high-affinity IgE receptor (FcεRI), MCs express numerous G protein-coupled receptors (GPCRs), which are the largest group of membrane receptor proteins and the most common targets of drug therapy...
September 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27146325/usage-of-allergy-codes-in-primary-care-electronic-health-records-a-national-evaluation-in-scotland
#3
Mome Mukherjee, Jeremy C Wyatt, Colin R Simpson, Aziz Sheikh
BACKGROUND: The UK's NHS intends to move from the current Read code system to the international, detailed Systematized Nomenclature of Medicine Clinical Terms (SNOMED-CT) to facilitate more clinically appropriate coding of conditions and associated risk factors and outcomes. Given concerns about coding behaviour of General Practitioners, we sought to study current coding patterns in allergies and identify lessons for the future migration to SNOMED-CT. METHODS: Data from 2,014,551 primary-care consultations in over 100,000 patients with one or more of 11 potentially allergic diseases (anaphylaxis, angioedema, asthma, conjunctivitis, drug allergies, eczema, food allergy, rhinitis, urticaria, venom allergy and other probable allergic disorders) from the Scottish Primary Care Clinical Informatics Unit Research (PCCIU-R) database were descriptively analysed and visualised to understand Read code usage patterns...
May 5, 2016: Allergy
https://www.readbyqxmd.com/read/26598817/food-and-natural-materials-target-mechanisms-to-effectively-regulate-allergic-responses
#4
Hee Soon Shin, Dong-Hwa Shon
An immune hypersensitivity disorder called allergy is caused by diverse allergens entering the body via skin contact, injection, ingestion, and/or inhalation. These allergic responses may develop into allergic disorders, including inflammations such as atopic dermatitis, asthma, anaphylaxis, food allergies, and allergic rhinitis. Several drugs have been developed to treat these allergic disorders; however, long-term intake of these drugs could have adverse effects. As an alternative to these medicines, food and natural materials that ameliorate allergic disorder symptoms without producing any side effects can be consumed...
2015: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/26483075/management-of-allergic-disease-in-the-elderly-key-considerations-recommendations-and-emerging-therapies
#5
REVIEW
Maria Teresa Ventura, Nicola Scichilone, Matteo Gelardi, Vincenzo Patella, Erminia Ridolo
The number of people over 65 is increasing around the world. At present, between 5 and 10% of allergic diseases affect the elderly. In particular, rhinitis is increasing worldwide; the presence of high comorbidity makes the therapy of asthma even more complicated. With reference to dermatological allergies, the dryness of the skin favors the onset of allergic contact and atopic dermatitis, while the senescence of mucous membranes and the impaired secretion of polymeric IgA could be linked to food allergy. Overcoming the problem of adverse drug reaction is limited by the diagnostic difficulty in patients taking multiple drugs...
2015: Expert Review of Clinical Immunology
https://www.readbyqxmd.com/read/26048266/off-label-uses-of-omalizumab
#6
David El-Qutob
The off-label use of medicines is a common and extensive clinical practice. Omalizumab has been licensed for use in severe allergic asthma and chronic urticaria. Omalizumab dosing was based on body weight and baseline serum IgE concentration. All patients are required to have a baseline IgE between 30 and 700 IU/ml and body weight not more than 150 kg. The use of off-label drugs may lead to several problems including adverse effects and an increased risk/benefit balance. In this article, there are summarized off-label uses of omalizumab in the last recent years in diseases in which IgE maybe or certainly has a corner role such as allergic rhinitis, allergic bronchopulmonary aspergillosis, anaphylaxis, keratoconjunctivitis, food allergy, drug allergy, urticaria, angioedema, non-atopic asthma, atopic dermatitis, nasal polyps, Churg-Strauss syndrome, eosinophilic otitis media, chronic rhinosinusitis, bullous pemphigoid, contact dermatitis, and others...
February 2016: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/25961393/asthma-allergy-and-the-olympics-a-12-year-survey-in-elite-athletes
#7
Matteo Bonini, Claudia Gramiccioni, Daniela Fioretti, Beate Ruckert, Monica Rinaldi, Cezmi Akdis, Antonio Todaro, Paolo Palange, Kai-Hakon Carlsen, Antonio Pelliccia, Guido Rasi, Sergio Bonini
OBJECTIVE: There are no comprehensive surveys relating the reported high prevalence of asthma and allergic diseases in athletes to comorbidities and immune changes associated with intense chronic exercise. This 12-year survey aims to evaluate several clinical, functional and immunological parameters in order to assess features, trend and burden of asthma, allergy, infections and autoimmune diseases, in a large homogeneous population of Olympic athletes. METHODS: Six hundred and fifty-nine Italian Olympic athletes were studied through four cross-sectional surveys performed between 2000 and 2012 before the Summer and Winter Olympics...
April 2015: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/25188717/sublingual-immunotherapy-in-children-the-recent-experiences
#8
REVIEW
Nicole Pleskovic, Ashton Bartholow, David P Skoner
PURPOSE OF REVIEW: Sublingual immunotherapy (SLIT) is indicated for the use in pediatric patients suffering from allergic rhinitis or allergic rhinoconjunctivitis caused by environmental allergens, such as ragweed pollen, grass pollen, and dust mite. This review focuses on recent and relevant studies associated with the use of SLIT for these allergens in children by examining efficacy, safety, and immunological data in comparison to subcutaneous immunotherapy, therapeutic treatments, and placebo...
December 2014: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/24565616/allergy-immunotherapy-safety-location-matters
#9
Linda Cox, Donald Aaronson, Thomas B Casale, Richard Honsinger, Richard Weber
Allergy immunotherapy is a highly effective therapy that has been used in the treatment of allergic rhinitis, asthma, and venom allergy for over a century. Subcutaneous immunotherapy (SCIT) is currently the only US Food and Drug Administration approved form of allergy immunotherapy. In this commentary, we address the safety issues that surround the location of care of SCIT administration in a supervised medical facility versus in the home or other medically unsupervised facility. Although analysis of the data suggests that SCIT has an excellent safety profile, we believe that this safety is largely due to the safety measures that are implemented when SCIT is administered in a medically supervised setting with appropriate staff and equipment to immediately recognize and treat anaphylaxis...
September 2013: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/24532966/omalizumab-an-anti-immunoglobulin-e-antibody-state-of-the-art
#10
Cristoforo Incorvaia, Marina Mauro, Marina Russello, Chiara Formigoni, Gian Galeazzo Riario-Sforza, Erminia Ridolo
A large number of trials show that the anti-immunoglobulin (Ig) E antibody omalizumab is very effective in patients with severe allergic asthma. This is acknowledged in consensus documents. The drug also has a good safety profile and a pharmacoeconomic advantage due to a reduction in the number of hospitalizations for asthma attacks. In recent years, some studies have shown that omalizumab is effective also in nonallergic asthma. Effects on the complex signaling mechanisms leading to activation of effector cells and to mediator release may account for this outcome...
2014: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/24472564/a-case-of-anaphylaxis-to-peppermint
#11
Roian Bayat, Rozita Borici-Mazi
BACKGROUND: Anaphylaxis, a form of IgE mediated hypersensitivity, arises when mast cells and possibly basophils are provoked to secrete mediators with potent vasoactive and smooth muscle contractile activities that evoke a systemic response. We report a case of IgE mediated anaphylaxis to peppermint (Mentha piperita) in a male shortly after sucking on a candy. CASE PRESENTATION: A 69 year old male developed sudden onset of lip and tongue swelling, throat tightness and shortness of breath within five minutes of sucking on a peppermint candy...
2014: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/24404400/a-case-of-codeine-induced-anaphylaxis-via-oral-route
#12
Hye-Soo Yoo, Eun-Mi Yang, Mi-Ae Kim, Sun-Hyuk Hwang, Yoo-Seob Shin, Young-Min Ye, Dong-Ho Nahm, Hae-Sim Park
Codeine is widely prescribed in clinical settings for the relief of pain and non-productive coughs. Common adverse drug reactions to codeine include constipation, euphoria, nausea, and drowsiness. However, there have been few reports of serious adverse reactions after codeine ingestion in adults. Here, we present a case of severe anaphylaxis after oral ingestion of a therapeutic dose of codeine. A 30-year-old Korean woman complained of the sudden onset of dyspnea, urticaria, chest tightness, and dizziness 10 minutes after taking a 10-mg dose of codeine to treat a chronic cough following a viral infection...
January 2014: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/23651601/progress-in-pediatrics-in-2012-choices-in-allergy-endocrinology-gastroenterology-hematology-infectious-diseases-neurology-nutrition-and-respiratory-tract-illnesses
#13
REVIEW
Carlo Caffarelli, Francesca Santamaria, Alessandra Vottero, Sergio Bernasconi
In this review, we summarize the progresses in allergy, endocrinology, gastroenterology, hematology, infectious diseases, neurology, nutrition and respiratory tract illnesses that have been published in The Italian Journal of Pediatrics in 2012. The induction of Treg activity by probiotics might be effective for promoting tolerance towards food allergens. Nasal cytology is useful in patients with rhinitis for diagnosing chronic non-allergic non-infectious diseases. Atopic eczema is associated both with an aberrant skin matrix and impaired systemic immune response...
May 8, 2013: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/23532243/sublingual-immunotherapy-for-the-treatment-of-allergic-rhinoconjunctivitis-and-asthma-a-systematic-review
#14
REVIEW
Sandra Y Lin, Nkiruka Erekosima, Julia M Kim, Murugappan Ramanathan, Catalina Suarez-Cuervo, Yohalakshmi Chelladurai, Darcy Ward, Jodi B Segal
IMPORTANCE: Allergic rhinitis affects up to 40% of the US population. To desensitize allergic individuals, subcutaneous injection immunotherapy or sublingual immunotherapy may be administered. In the United States, sublingual immunotherapy is not approved by the Food and Drug Administration. However, some US physicians use aqueous allergens, off-label, for sublingual desensitization. OBJECTIVE: To systematically review the effectiveness and safety of aqueous sublingual immunotherapy for allergic rhinoconjunctivitis and asthma...
March 27, 2013: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/23352528/anaphylaxis-in-a-tertiary-adult-allergy-clinic-a-retrospective-review-of-516%C3%A2-patients
#15
Aslı Gelincik, Mustafa Demirtürk, Emre Yılmaz, Belkıs Ertek, Derya Erdogdu, Bahattin Çolakoğlu, Suna Büyüköztürk
BACKGROUND: Anaphylaxis is a life-threatening acute allergic reaction that can occur at any age. OBJECTIVE: To determine the frequency, triggering factors, and clinical features of anaphylaxis among adult patients who were referred to a tertiary health care facility. METHODS: A retrospective medical chart review was performed including all patients referred to the outpatient clinic of the adult allergy department in our university hospital between January 1, 2008 and December 30, 2011 to determine cases involving anaphylaxis...
February 2013: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/22994350/lipid-transfer-protein-syndrome-clinical-pattern-cofactor-effect-and-profile-of-molecular-sensitization-to-plant-foods-and-pollens
#16
M Pascal, R Muñoz-Cano, Z Reina, A Palacín, R Vilella, C Picado, M Juan, J Sánchez-López, M Rueda, G Salcedo, A Valero, J Yagüe, J Bartra
BACKGROUND: Multiple plant-food sensitizations with a complex pattern of clinical manifestations are a common feature of lipid transfer protein (LTP)-allergic patients. Component-resolved diagnosis permits the diagnosis of the allergen sensitization profile. OBJECTIVE: We sought to clinically characterize and describe the plant-food and pollen molecular sensitization profile in patients with LTP syndrome. METHODS: Forty-five subjects were recruited, after being diagnosed with multiple plant-food allergies sensitized to LTP, but not to any other plant-food allergen, according to the molecular allergen panel tested (Pru p 3 (LTP), Pru p 1 (Bet v 1-like), Pru p 4 (profilin) and those included in a commercial microarray of 103 allergenic components)...
October 2012: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/22794675/chapter-2-skin-testing-in-allergy
#17
REVIEW
Tara F Carr, Carol A Saltoun
Skin tests are used in addition to a directed history and physical exam to exclude or confirm IgE-mediated diseases such as allergic rhinitis, asthma, and anaphylaxis to aeroallergens, foods, insect venoms, and certain drugs. There are two types of skin testing used in clinical practice. These include percutaneous testing (prick or puncture) and intracutaneous testing (intradermal). Prick testing involves introducing a needle into the upper layers of the skin through a drop of allergen extract and gently lifting the epidermis up...
May 2012: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/22640224/allergen-specific-immunotherapy-from-therapeutic-vaccines-to-prophylactic-approaches
#18
REVIEW
R Valenta, R Campana, K Marth, M van Hage
Immunoglobulin E-mediated allergies affect more than 25% of the population. Allergen exposure induces a variety of symptoms in allergic patients, which include rhinitis, conjunctivitis, asthma, dermatitis, food allergy and life-threatening systemic anaphylaxis. At present, allergen-specific immunotherapy (SIT), which is based on the administration of the disease-causing allergens, is the only disease-modifying treatment for allergy. Current therapeutic allergy vaccines are still prepared from relatively poorly defined allergen extracts...
August 2012: Journal of Internal Medicine
https://www.readbyqxmd.com/read/21781403/biological-terrorism-and-the-allergist-s-office-practice
#19
Anthony J Ricketti, Burke A Cunha, Dennis J Cleri, Suzanne H Shenk, John R Vernaleo, David W Unkle
During the anthrax outbreak and threat in Trenton (2001), our allergy practice experienced increased visits from approximately 50 of our regular patients with symptoms they believed resulted from anthrax exposure. In all cases, their symptoms were caused by a combination of an exacerbation of their underlying allergic disease and anxiety because of possible exposure to anthrax. Our objective is to present an orderly approach to the allergist's outpatients presenting with possible exposure to a bioterrorist's agent...
July 2011: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/21437139/leukotriene-receptor-antagonists-in-monotherapy-or-in-combination-with-antihistamines-in-the-treatment-of-chronic-urticaria-a-systematic-review
#20
Gabriele Di Lorenzo, Alberto D'Alcamo, Manfredi Rizzo, Maria Stefania Leto-Barone, Claudia Lo Bianco, Vito Ditta, Donatella Politi, Francesco Castello, Ilenia Pepe, Gaetana Di Fede, Giovambattista Rini
In vitro and in vivo clinical and experimental data have suggested that leukotrienes play a key role in inflammatory reactions of the skin. Antileukotriene drugs, ie, leukotriene receptor antagonists and synthesis inhibitors, are a class of anti-inflammatory drugs that have shown clinical efficacy in the management of asthma and in rhinitis with asthma. We searched MEDLINE database and carried out a manual search on journals specializing in allergy and dermatology for the use of antileukotriene drugs in urticaria...
2008: Journal of Asthma and Allergy
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