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Dual x-ray absorbtiometry

Karen Fjeldborg, Steen B Pedersen, Holger J Møller, Bjørn Richelsen
BACKGROUND: Fibroblast growth factor 21 (FGF21) is elevated in obesity. OBJECTIVES: We investigated the circulating level of FGF21 and the expression of FGF21, beta-klotho (KLB), and FGF receptor 1 (FGFR1) in adipose tissue in relation to weight, fat distribution, and Roux-en-Y gastric bypass (RYGB)-induced weight loss. SETTING: The Department of Endocrinology at Aarhus University Hospital. METHODS: Thirty-one obese patients were enrolled...
September 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
Barry J Sheane, Paul Smyth, Kenneth Scott, Raschid Aziz, Mella Buckley, Emer Lodge, Niamh Kiely, Mary Kingston, Eilis McGovern, Martin Healy, J B Walsh, Orla Sheils, Gaye Cunnane
BACKGROUND: Atherosclerosis-related cardiovascular disease and osteoporosis (OP) occur concurrently and may share a common pathogenesis. Aberrant expression of miR-21 and vitamin D deficiency have been independently linked to the pathogenesis of atherosclerosis and OP. OBJECTIVES: To examine the relationship between miR-21 expression and vitamin D in aorta and bone in atherosclerotic disease. METHODS: Aorta, internal mammary artery (IMA) and sternal bone samples were collected from patients undergoing coronary artery bypass graft (CABG) surgery...
2015: MicroRNA
Frederick M Ivey, Alice S Ryan
BACKGROUND: Insulin resistance is highly prevalent after stroke, contributing to comorbid cardiovascular conditions that are the leading cause of death in the stroke population. This study determined the effects of unilateral resistive training (RT) of both the paretic and nonparetic legs on insulin sensitivity in stroke survivors. METHODS: We studied 10 participants (mean age 65 ± 2 years; mean body mass index 27 ± 4 kg/m2) with hemiparetic gait after remote (>6 months) ischemic stroke...
February 2014: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Jameela Banu, Erika Varela, Juan M Guerra, Ganesh Halade, Paul J Williams, Ali N Bahadur, Kokichi Hanaoka, Gabriel Fernandes
In patients diagnosed with osteoporosis, calcium is lost from bones making them weaker and easily susceptible to fractures. Supplementation of calcium is highly recommended for such conditions. However, the source of calcium plays an important role in the amount of calcium that is assimilated into bone. We hypothesize that naturally occurring coral calcium and zeolite may prevent ovariectomy-induced bone loss. We have measured bone loss in ovariectomized mice supplemented with coral calcium and Zeolite. Female C57BL/6 mice were either sham-operated or ovariectomized and fed diets containing coral calcium or zeolite for 6 months...
December 2012: Nutrition Research
Steve Innes, Mark F Cotton, Richard Haubrich, Maria M Conradie, Margaret van Niekerk, Clair Edson, Helena Rabie, Sonia Jain, Xiaoying Sun, Ekkehard W Zöllner, Stephen Hough, Sara H Browne
BACKGROUND: Despite changes in WHO guidelines, stavudine is still used extensively for treatment of pediatric HIV in the developing world. Lipoatrophy in sub-Saharan African children can be stigmatizing and have far-reaching consequences. The severity and extent of lipoatrophy in pre-pubertal children living in sub-Saharan Africa is unknown. METHODS: In this cross-sectional study, children who were 3-12 years old, on antiretroviral therapy and pre-pubertal were recruited from a Family HIV Clinic in South Africa...
2012: BMC Pediatrics
Franco Lumachi, Rocco Orlando, Francesco Fallo, Stefano M M Basso
Bone remodeling is altered in all metabolic bone diseases, especially in post-menopausal women and in the elderly. Predicting changes in bone mineral density (BMD) is useful to manage the progression of such diseases and to potentially provide interventions in reducing fracture risk. Continuous bone formation and resorption processes can be monitored by measuring biochemical markers of bone turnover (BTMs) and a relationship between BMD and BTMs has been known for long. The aim of this study was to evaluate the relationship between BMD and serum BTMs bone alkaline phosphatase (BAP), osteocalcin and amino-terminal propeptide of type I collegen (PINP) in elderly (>65 years) men...
November 2012: In Vivo
Luana Macovei, Codrina Ancuţa, Codruţa Belibou, Rodica Chirieac
UNLABELLED: Patients with rheumatoid arthritis (RA), an immune-mediated inflammatory rheumatic disease with peripheral and systemic involvement, are at increased risk of bone loss and fractures. There are many reasons for the high prevalence of osteoporosis (OP) in RA, including both traditional and specific risk factors such as pain and loss of joint function, medication (corticosteroids, methotrexate), and increased proinflammatory cytokines. AIM: To evaluate bone mineral density status in RA patients, focusing on potential relation with classical risk factors for OP...
July 2011: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
Jaroslava Wendlová
BACKGROUND: The geometric configuration of the proximal femur predicts the risk for fracture by fall independently of bone mineral density (BMD). The objective of the study was to determine the expected frequency of biomechanically adverse and extremely adverse values of proximal femur geometric variables alpha angle, theta angle, and HAL, increasing the risk of a femoral neck fracture by fall, in the East Slovak female population. METHODS: DXA (dual energy X-ray absorbtiometry) measurements of the left proximal femur were obtained and analysed from sample 3151 East Slovak women aged 20-89 years, [Formula: see text] = 58...
October 2011: Wiener Medizinische Wochenschrift
Grace A McComsey, Douglas Kitch, Eric S Daar, Camlin Tierney, Nasreen C Jahed, Pablo Tebas, Laurie Myers, Kathleen Melbourne, Belinda Ha, Paul E Sax
BACKGROUND: Long-term effects of abacavir (ABC)-lamivudine (3TC), compared with tenofovir (TDF)-emtricitabine (FTC) with efavirenz (EFV) or atazanavir plus ritonavir (ATV/r), on bone mineral density (BMD) have not been analyzed. METHODS: A5224s was a substudy of A5202, in which HIV-infected treatment-naive participants were randomized and blinded to receive ABC-3TC or TDF-FTC with open-label EFV or ATV/r. Primary bone end points included Dual-emission X-ray absorbtiometry (DXA)-measured percent changes in spine and hip BMD at week 96...
June 15, 2011: Journal of Infectious Diseases
Naciye Yildiz Turkozan, Ceyhun Mammadov
AIM: The aim of the study was to compare the body and angle of the sheep mandible in terms of bone density and biomechanical competence under bending load conditions. MATERIAL AND METHODS: Nineteen sheep mandibles were used in this study. The mandibles were separated at the symphysis into two halves. Three regions of interest on the body and angle of the hemi-mandibles were selected for measurements of bone mineral density (g cm(-2) ) by dual energy X-ray absorbtiometry...
June 2011: Dental Traumatology: Official Publication of International Association for Dental Traumatology
Jørn W Helge, Ditte K Klein, Thor Munch Andersen, Gerrit van Hall, Jose Calbet, Robert Boushel, Bengt Saltin
Exercising muscle releases interleukin-6 (IL-6), but the mechanisms controlling this process are poorly understood. This study was performed to test the hypothesis that the IL-6 release differs in arm and leg muscle during whole-body exercise, owing to differences in muscle metabolism. Sixteen subjects (10 men and six women, with body mass index 24 ± 1 kg m(-2) and peak oxygen uptake 3.4 ± 0.6 l min(-1)) performed a 90 min combined arm and leg cycle exercise at 60% of maximal oxygen uptake. The subjects arrived at the laboratory having fasted overnight, and catheters were placed in the femoral artery and vein and in the subclavian vein...
June 2011: Experimental Physiology
Derya Bugdayci, Nurdan Paker, Didem Dere, Emel Özdemir, Nurhan Ince
Falling is a major complication seen in stroke patients. The purpose of this study was to investigate the frequency, features, and factors for falls affecting subacute stroke patients hospitalized for rehabilitation. Ninety-nine subacute stroke patients, hospitalized for rehabilitation were evaluated prospectively in this study. All patients were evaluated using the functional independence measurement (FIM), the Barthel index (BI), the Berg balance scale (BBS), the mini mental state examination (MMSE), the hospital anxiety depression scale (HADS), and the Downton index (DI), performed by the same physician...
May 2011: Archives of Gerontology and Geriatrics
C Jimenez, M Ayala-Ramirez, J Liu, R Nunez, R F Gagel
Treatment of acromegaly with pegvisomant lowers serum IGF-1 and raises serum growth hormone. As both IGF-1 and GH are important for bone growth and remodeling, we were concerned that lowering of IGF-1 could cause loss of bone. To evaluate the effects of treatment of acromegaly with pegvisomant on bone mineral density (BMD) we developed an observational, prospective study. 7 acromegaly patients participated in the study. Male and female subjects aged 18 years or more were eligible to participate. Patients were eugonadal or on adequate gonadal replacement therapy for at least 3 years before participating in the study...
January 2011: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
Joey C Eisenman, Mark A Sarzynski, Jerod Tucker, Kate A Heelan
The purpose of this study was to examine if offspring physical activity may affect the relationship between maternal overweight and offspring fatness and blood pressure (BP). Subjects included 144 maternal-child pairs (n = 74 boys and 70 girls, mean age = 7.3 yrs). Maternal prepregnancy BMI was determined by self-report. Offspring characteristics included resting systolic and diastolic BP, body fatness by dual energy x-ray absorbtiometry, and moderate-to-vigorous physical activity (MVPA) using the Actigraph accelerometer...
August 2010: Pediatric Exercise Science
H Al-Turki
BACKGROUND: Sickle cell disease (SCD) causes osteopenia and osteoporosis, This osteopenia may be further influenced by pregnancy. OBJECTIVE: To find out the effect of pregnancy on bone skeleton density in patients with SCD. METHODS: Consecutive adult female SCA patients who were treated at the out-patients clinics of King Fahd University Hospital Al-Khobar, Saudi Arabia, between January and July 2007, were the cases of study. Patient's age, number of pregnancies and duration after pregnancy were documented...
May 2009: West African Journal of Medicine
S Ziaran, F M Goncalves, J Wendl, B Trebaticky, J Sn Breza
BACKGROUND: Men with prostate cancer older than 60 years who are treated with androgen deprivation therapy (ADT) represent a specific subpopulation of patients being at high risk of bone loss and subsequent complications. In contrast to this fact, there is not much data (if any) about this specific subpopulation of men and their BMD prior to the start of ADT. The aim of this study is to evaluate BMD in such patients. PATIENTS AND METHODS: Femoral neck and lumbar spine (L1-L4) were determined by dual-x-ray absorbtiometry (DXA) in 80 men (mean age 75...
2009: Bratislavské Lekárske Listy
Gulseren Kayalar, Alev Cevikol, Gunes Yavuzer, Yavuz Sanisoglu, Aytul Cakci, Tansu Arasil
OBJECTIVE: To evaluate how bone mineral density in the calcaneus measured by a dual energy X-ray laser (DXL) correlates with bone mineral density in the spine and hip in Turkish women over 40 years of age and to determine whether calcaneal dual energy X-ray laser variables are associated with clinical risk factors to the same extent as axial bone mineral density measurements obtained using dual energy x-ray absorbtiometry (DXA). MATERIALS AND METHODS: A total of 2,884 Turkish women, aged 40-90 years, living in Ankara were randomly selected...
2009: Clinics
Ulf E W Sigurdsen, Olav Reikeras, Stein Erik Utvag
BACKGROUND AND PURPOSE: It is not known whether there is a difference in bone healing after external fixation and after intramedullary nailing. We therefore compared fracture healing in rats after these two procedures. METHODS: 40 male rats were subjected to a standardized tibial shaft osteotomy and were randomly assigned to 2 treatment groups: external fixation or intramedullary nailing. Evaluation of half of each treatment group at 30 days and the remaining half at 60 days included radiography, dual energy radiographic absorbtiometry, and mechanical testing...
June 2009: Acta Orthopaedica
M Sadat-Ali, A H Al-Elq, O Sultan, H Al-Turki, R Bukhari, E Al-Mulhim
BACKGROUND: The prevalence of sickle cell anemia in Saudi population was reported to be between 0-5.27%. OBJECTIVE: This cross-sectional study was conducted to assess the prevalence of osteoporosis and osteopenia in patients with sickle cell anemia and to correlate its severity with the hematological parameters. METHODS: A cross-sectional study which included consecutive adult patients with sickle cell anemia attending the outpatient clinics or were admitted with uncomplicated vaso-occlusive crisis to King Fahd University Hospital, Al Khobar, Saudi Arabia, between August 2006 and March 2007 was undertaken...
October 2008: West African Journal of Medicine
Joey C Eisenmann, Mark A Sarzynski, Kim Glenn, Max Rothschild, Kate A Heelan
BACKGROUND: Angiotensin converting enzyme (ACE) is a possible candidate gene that may influence both body fatness and blood pressure. Although several genetic studies have been conducted in adults, relatively few studies have examined the contribution of potential candidate genes, and specifically ACE I/D, on adiposity and BP phenotypes in childhood. Such studies may prove insightful for the development of the obesity-hypertension phenotype early in life. The purpose of this study was to examine differences in body fatness and resting blood pressure (BP) by ACE I/D genotype, and determine if the association between adiposity and BP varies by ACE I/D genotype in children...
2009: Cardiovascular Diabetology
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