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https://www.readbyqxmd.com/read/28530076/-osteoporosis-and-diabetes-in-which-way-are-they-related
#1
REVIEW
Osnat Tell-Lebanon, Pnina Rotman-Pikielny
Diabetes and osteoporosis are common diseases with growing prevalence in the aging population. Many recent studies have reported an association between diabetes mellitus and an increased osteoporotic fracture rate. Compared to control subjects, decreased bone mineral density has been observed in patients with type 1 diabetes mellitus, while those with type 2 diabetes display a unique skeletal phenotype of increased bone mineral density, but impaired architectural structure and mineral properties. Accumulation of advanced glycation end products changes collagen structure and suppression of bone turnover causes impairment of repair and adaptation mechanisms...
November 2016: Harefuah
https://www.readbyqxmd.com/read/28528793/comparison-of-dual-energy-x-ray-absorptiometry-and-bioimpedance-in-assessing-body-composition-and-nutrition-in-peritoneal-dialysis-patients
#2
Velena Popovic, Bo Zerahn, James Goya Heaf
OBJECTIVE: Peritoneal dialysis (PD) patients are characterized by protein malnutrition and muscle wasting. Reliable, easy, and cheap methods for evaluating nutrition are desirable. Three methods are commonly available: dual-energy X-ray absorptiometry (DXA), bioimpedance (BI), and subjective global assessment (SGA).The objective of the study was to compare the previously mentioned methods for assessment of body composition and nutritional status in PD patients. DESIGN: The study is cross-sectional and consisted of 72 PD patients from a single center PD ambulatorium...
May 18, 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/28528404/a-direct-comparison-of-the-effects-of-the-antiretroviral-drugs-stavudine-tenofovir-and-the-combination-lopinavir-ritonavir-on-bone-metabolism-in-a-rat-model
#3
M M Conradie, M van de Vyver, E Andrag, M Conradie, W F Ferris
Antiretroviral (ARV) treatment may induce metabolic complications in HIV patients on long-term therapy that can affect bone health. In this study, the effects of the ARVs Stavudine (d4T), Tenofovir (TDF) and Lopinavir/ritonavir (LPV/r) on bone metabolism and lipodystrophy were directly compared in rats to negate the consequences of HIV-associated confounding factors. Healthy 12-14-week-old male Wistar rats (n = 40) were divided into four treatment groups and received an oral animal equivalent dose of either Stavudine (6...
May 20, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28527105/association-between-lumbar-bone-mineral-density-and-serum-uric-acid-in-postmenopausal-women-a-cross-sectional-study-of-healthy-chinese-population
#4
Wen Han, Xiaojuan Bai, Nan Wang, Lulu Han, Xuefeng Sun, Xiangmei Chen
Partial correlation and regression analyses were used in this study. We showed that there is a linear relationship between bone mineral density and serum uric acid within the normal physiologic range, and higher serum uric acid levels had a protective effect on bone loss in postmenopausal osteoporosis. PURPOSE: The significance of the relationship between lumbar bone mineral density (()BMD) and serum uric acid (SUA) levels is unclear. The aims of this study were to investigate on a population-level the association between lumbar BMD and SUA within the normal physiologic range and to determine whether SUA plays a protective role in bone loss in healthy postmenopausal Chinese women...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28526625/effects-of-resistance-training-frequency-on-cardiorespiratory-fitness-in-older-men-and-women-during-intervention-and-follow-up
#5
Elena Fernández-Lezaun, Moritz Schumann, Tuomas Mäkinen, Heikki Kyröläinen, Simon Walker
This study investigated the effects of resistance training (RT) performed with different frequencies, including a follow-up period, on cardiorespiratory fitness in healthy older individuals. Eighty-eight men and women (69±3years, 167±9cm and 78±14kg) were randomly placed into four groups: training one- (M1=11, W1=12), two- (M2=7, W2=14), or three- (M3=11, W3=13) times-per-week or a non-training control group (MCon=11, WCon=9). During months 1-3, all subjects trained two-times-per-week while during the subsequent 6months, training frequency was set according to the group...
May 16, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28526284/low-bone-mineral-density-may-be-associated-with-long-term-risk-of-cancer-in-the-middle-aged-population-a-retrospective-observational-study-from-a-single-center
#6
Hsin-Fu Lee, Chiao-En Wu, Yu-Sheng Lin, Jaw-Shan Hwang, Chu-Hua Wu, Pao-Hsien Chu
BACKGROUND: It is generally understood that cancer patients are at an increased risk for osteoporosis. Additionally, recent studies have suggested a shared pathophysiological mechanism between the development of cancer and osteoporosis. The purpose of this investigation was to investigate whether low bone mineral density is associated with cancer risk. METHODS: We enrolled 8780 subjects who underwent dual-energy X-ray absorptiometry (DXA) and cancer screening from January 1, 2008-December 31, 2012 from a cohort selected from Chang Gung Health Care Center in Taiwan...
May 16, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28516070/bone-density-in-postmenopausal-women-with-or-without-breast-arterial-calcification
#7
Atoosa Adibi, Farnaz Rabani, Silva Hovsepian
BACKGROUND: Identification of osteoporosis in women in order to prevent its related morbidity and mortality is considered a priority. Routine mammography is performed on all menopausal women as a screening tool. Determination of the relation between breast arterial calcification (BAC) on mammography and the bone density of this high-risk population could help us to determine those with osteoporosis. The aim of this study was to investigate the mentioned probable relation between BAC and osteoporosis...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28502885/contra-lateral-bone-loss-at-the-distal-radius-in-postmenopausal-women-after-a-distal-radius-fracture-a-two-year-follow-up-hrpqct-study
#8
Joost J A de Jong, Jacobus J C Arts, Paul C Willems, Sandrine P G Bours, Judith P A Bons, Paul P C A Menheere, Bert van Rietbergen, Piet P Geusens, Joop P W van den Bergh
Opposite to the fracture side, bone mineral density (BMD) measured by DXA at the contra-lateral side does not change after a distal radius fracture. However, it is unknown if also bone micro-architecture and strength at the contralateral side are unaffected. Therefore, the aim of this study was to assess BMD, micro-architecture and bone mechanical properties at the contra-lateral side during two years follow-up after a distal radius fracture using high resolution peripheral quantitative computed tomography (HRpQCT)...
May 11, 2017: Bone
https://www.readbyqxmd.com/read/28497224/bone-density-microarchitecture-and-material-strength-in-chronic-kidney-disease-patients-at-the-time-of-kidney-transplantation
#9
M J Pérez-Sáez, S Herrera, D Prieto-Alhambra, L Vilaplana, X Nogués, M Vera, D Redondo-Pachón, M Mir, R Güerri, M Crespo, A Díez-Pérez, J Pascual
Bone health is assessed by bone mineral density (BMD). Other techniques such as trabecular bone score and microindentation could improve the risk of fracture's estimation. Our chronic kidney disease (CKD) patients presented worse bone health (density, microarchitecture, mechanical properties) than controls. More than BMD should be done to evaluate patients at risk of fracture. INTRODUCTION: BMD measured by dual-energy X-ray absorptiometry (DXA) is used to assess bone health in end-stage renal disease (ESRD) patients...
May 11, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28493988/prediction-of-whole-body-fat-percentage-and-visceral-adipose-tissue-mass-from-five-anthropometric-variables
#10
Michelle G Swainson, Alan M Batterham, Costas Tsakirides, Zoe H Rutherford, Karen Hind
BACKGROUND: The conventional measurement of obesity utilises the body mass index (BMI) criterion. Although there are benefits to this method, there is concern that not all individuals at risk of obesity-associated medical conditions are being identified. Whole-body fat percentage (%FM), and specifically visceral adipose tissue (VAT) mass, are correlated with and potentially implicated in disease trajectories, but are not fully accounted for through BMI evaluation. The aims of this study were (a) to compare five anthropometric predictors of %FM and VAT mass, and (b) to explore new cut-points for the best of these predictors to improve the characterisation of obesity...
2017: PloS One
https://www.readbyqxmd.com/read/28493277/bone-mineral-density-in-complete-androgen-insensitivity-syndrome-and-the-timing-of-gonadectomy
#11
Thomas F J King, Winnie Z M Wat, Sarah M Creighton, Gerard S Conway
OBJECTIVE: Low bone mineral density (BMD) has been reported in complete androgen insensitivity syndrome (CAIS), but the impact of timing of gonadectomy is not known. We aimed to assess the relationship between age of gonadectomy and BMD in women with CAIS. DESIGN: Retrospective analysis of pre- and post-gonadectomy parameters in women with CAIS attending an adult Disorders of Sex Development (DSD) clinic in a tertiary centre. PATIENTS: One hundred and thirteen women with CAIS...
May 10, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28488133/are-bilateral-decubitus-views-necessary-in-assessing-for-vertebral-compression-fractures-using-dxa-vertebral-fracture-assessment
#12
Y-C Lin, T-S Huang, J S Wu, Y-C Cheung, Y-H Huang, C-M Sung, Y-H Juan, F-P Chen, J M Ni Mhuircheartaigh
The purpose of this study is to assess the differences in VFA diagnostic accuracy when using bilateral decubitus views and whether diagnostic accuracy is affected by scoliosis. Our findings show that the current practice of performing only one side is valid; however, bilateral views can improve specificity in scoliosis. INTRODUCTION: The diagnostic accuracy of vertebral fracture assessment (VFA) can be influenced by poor patient position and scoliosis. This study aims to assess the differences in VFA diagnostic accuracy for right and left lateral decubitus views and the effect of scoliosis...
May 9, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28487552/newborn-insula-gray-matter-volume-is-prospectively-associated-with-early-life-adiposity-gain
#13
J M Rasmussen, S Entringer, F Kruggel, D M Cooper, M Styner, J H Gilmore, S G Potkin, P D Wadhwa, C Buss
BACKGROUNDThe importance of energy homeostasis brain circuitry in the context of obesity is well established, however, the developmental ontogeny of this circuitry in humans is currently unknown. Here, we investigate the prospective association between newborn gray matter (GM) volume in the insula, a key brain region underlying energy homeostasis, and change in percent body fat accrual over the first six months of postnatal life, an outcome that represents among the most reliable infant predictors of childhood obesity risk...
May 10, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28486441/bone-mineral-density-in-patients-with-inherited-bone-marrow-failure-syndromes
#14
Roopa Kanakatti Shankar, Neelam Giri, Maya B Lodish, Ninet Sinaii, James C Reynolds, Sharon A Savage, Constantine A Stratakis, Blanche P Alter
BACKGROUNDPatients with inherited bone marrow failure syndromes (IBMFS) may have several risk factors for low bone mineral density (BMD). We aimed to evaluate the prevalence of low BMD in IBMFS and determine associated risk factors.METHODSPatients with IBMFS with at least one Dual Energy X-ray absorptiometry (DXA) scan were evaluated. Diagnosis of each IBMFS, Fanconi anemia (FA), dyskeratosis congenita, Diamond-Blackfan anemia, and Shwachman-Diamond syndrome, was confirmed by syndrome-specific tests. Data were gathered on age, height and clinical history...
May 9, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28486005/reference-values-for-assessment-of-unilateral-limb-lymphedema-with-dual-energy-x-ray-absorptiometry
#15
Caroline A Gjorup, Helle W Hendel, Tobias W Klausen, Bo Zerahn, Lisbet R Hölmich
INTRODUCTION: The clinical assessment of unilateral limb lymphedema is commonly based on measurements of interlimb volume differences. Reference values for interlimb percentage differences of the volume, fat mass, and lean mass measured with dual-energy X-ray absorptiometry (DXA) scan are, however, not established. The aim of the study was to establish and categorize these reference values in normal limbs. METHODS AND RESULTS: DXA scans of the normal arms of 167 and normal legs of 196 melanoma patients (aged 18-75 years, body mass index <40), respectively, were performed...
May 9, 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28479964/relationship-between-academic-performance-with-physical-psychosocial-lifestyle-and-sociodemographic-factors-in-female-undergraduate-students
#16
Marie-Maude Dubuc, Mylène Aubertin-Leheudre, Antony D Karelis
BACKGROUND: The purpose of this study was to investigate the relationship between physical, psychosocial, lifestyle and sociodemographic factors with academic performance in female undergraduate students. METHODS: One hundred undergraduate female students from the Faculty of Science at the University of Quebec at Montreal participated in this study (mean age = 24.4 ± 4.6 years old). All participants provided their university transcript and had to complete at least 45 course credits from their bachelor degree...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28476576/non-bmd-dxa-measurements-of-the-hip
#17
Clinten P Edmondson, Elliott N Schwartz
Hip fracture is one of the most serious complications of osteoporosis. More than 50% of hip and other fractures occur in patients without densitometric osteoporosis. Therefore, areal bone mineral density (aBMD) may not be the best way to assess fracture risk. In order to improve assessment of fracture risk, many other approaches have been taken. At the present time, the Fracture Risk Algorithm (FRAX©) is one of the most notable ways to improve assessment of fracture risk. However, since early in the initiation of the dual energy x-ray absorptiometry (DXA) era, several non-BMD DXA approaches to the assessment of hip fracture risk have been proposed...
May 2, 2017: Bone
https://www.readbyqxmd.com/read/28474785/protein-timing-during-the-day-and-its-relevance-for-muscle-strength-and-lean-mass
#18
Samuel L Buckner, Jeremy P Loenneke, Paul D Loprinzi
Protein consumption and its association with changes in body composition, muscle function and different strategies to optimize the muscle protein synthetic response have received considerable attention. However, we are not aware of any epidemiological study examining the time-of-day consumption (afternoon versus evening) of protein on strength and lean mass. The purpose was to examine the associations between afternoon and evening protein consumption, at different protein thresholds (i.e. 15, 20, 25 and 30 g), in relation to leg lean mass and knee extensor strength in men...
May 5, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28473075/acr-appropriateness-criteria-%C3%A2-osteoporosis%C3%A2-and%C3%A2-bone-mineral-density
#19
Robert J Ward, Catherine C Roberts, Jenny T Bencardino, Erin Arnold, Steven J Baccei, R Carter Cassidy, Eric Y Chang, Michael G Fox, Bennett S Greenspan, Soterios Gyftopoulos, Mary G Hochman, Douglas N Mintz, Joel S Newman, Charles Reitman, Zehava S Rosenberg, Nehal A Shah, Kirstin M Small, Barbara N Weissman
Osteoporosis is a considerable public health risk, with 50% of women and 20% of men >50 years of age experiencing fracture, with mortality rates of 20% within the first year. Dual x-ray absorptiometry (DXA) is the primary diagnostic modality by which to screen women >65 years of age and men >70 years of age for osteoporosis. In postmenopausal women <65 years of age with additional risk factors for fracture, DXA is recommended. Some patients with bone mineral density above the threshold for treatment may qualify for treatment on the basis of vertebral body fractures detected through a vertebral fracture assessment scan, a lateral spine equivalent generated from a commercial DXA machine...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28472894/resting-energy-expenditure-in-male-athletes-with-a-spinal-cord-injury
#20
Fiona E Pelly, Elizabeth M Broad, Natalie Stuart, Mark A Holmes
OBJECTIVE: To investigate whether there are differences in the resting energy expenditure (REE) and body composition of athletes with a spinal cord injury (SCI) compared to active able-bodied controls. DESIGN: In this cross sectional study, male athletes with a SCI were compared to active able-bodied controls matched for age, stretch stature and body mass. In addition, the accuracy of standard REE prediction equations in estimating REE was assessed. PARTICIPANTS: Seven male wheelchair athletes with a SCI and six matched active able-bodied controls volunteered to participate...
May 4, 2017: Journal of Spinal Cord Medicine
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