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https://www.readbyqxmd.com/read/27933656/change-in-trabecular-bone-score-tbs-with-antiresorptive-therapy-does-not-predict-fracture-in-women-the-manitoba-bmd-cohort
#1
William D Leslie, Sumit R Majumdar, Uzanne N Morin, Didier Hans, Lisa M Lix
Bone mineral density (BMD) and trabecular bone score (TBS), along with additional clinical risk factors, can be used to identify individuals at high fracture risk. Whether change in TBS in untreated or treated women independently affects fracture risk is unclear. Using the Manitoba (Canada) DXA Registry containing all BMD results for the population we identified 9044 women age >40 years with two consecutive DXA scans and who were not receiving osteoporosis treatment at baseline (baseline mean age 62 ± 10 years)...
December 8, 2016: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/27924381/dual-energy-x-ray-absorptiometry-and-fracture-prediction-in-patients-with-spinal-cord-injuries-and-disorders
#2
L Abderhalden, F M Weaver, M Bethel, H Demirtas, S Burns, J Svircev, H Hoenig, K Lyles, S Miskevics, L D Carbone
: Low T-scores at the hip predict incident fractures in persons with a SCI. INTRODUCTION: Persons with a spinal cord injury (SCI) have substantial morbidity and mortality following osteoporotic fractures. The objective of this study was to determine whether dual-energy X-ray absorptiometry (DXA) measurements predict osteoporotic fractures in this population. METHODS: A retrospective historical analysis that includes patients (n = 552) with a SCI of at least 2 years duration who had a DXA performed and were in the VA Spinal Cord Disorders Registry from fiscal year (FY) 2002-2012 was performed...
December 6, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27922574/drop-body-syndrome-a-distinct-form-of-adult-spinal-deformity
#3
Mitsuru Yagi, Shinjiro Kaneko, Yoshiyuki Yato, Takashi Asazuma
STUDY DESIGN: A retrospective observational study. OBJECTIVE: This study examined the role of skeletal muscles in the spinal alignment of lumbar degenerative kyphosis (LDK). SUMMARY OF BACKGROUND DATA: Adult spinal deformity (ASD) may present as LDK, which is unusual in that it typically lacks any coronal deformity. METHODS: This retrospective study included 367 female ASD. Demographic and radiographic data from LDKs were compared with those with other ASD...
December 2, 2016: Spine
https://www.readbyqxmd.com/read/27921146/bone-loss-at-the-distal-femur-and-proximal-tibia-in-persons-with-spinal-cord-injury-imaging-approaches-risk-of-fracture-and-potential-treatment-options
#4
REVIEW
C M Cirnigliaro, M J Myslinski, M F La Fountaine, S C Kirshblum, G F Forrest, W A Bauman
Persons with spinal cord injury (SCI) undergo immediate unloading of the skeleton and, as a result, have severe bone loss below the level of lesion associated with increased risk of long-bone fractures. The pattern of bone loss in individuals with SCI differs from other forms of secondary osteoporosis because the skeleton above the level of lesion remains unaffected, while marked bone loss occurs in the regions of neurological impairment. Striking demineralization of the trabecular epiphyses of the distal femur (supracondylar) and proximal tibia occurs, with the knee region being highly vulnerable to fracture because many accidents occur while sitting in a wheelchair, making the knee region the first point of contact to any applied force...
December 5, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27920813/densitometric-evaluation-of-bone-prosthetic-counterface-in-hip-and-knee-arthroplasty-with-modern-implants
#5
Andrea Cozzi Lepri, Marco Giorgini, Carla Signorini, Christian Carulli, Roberto Civinini, Maria Luisa Brandi, Massimo Innocenti
INTRODUCTION: Recent acquisitions of the complex mechanisms of osseointegration between implants and host bone have gained attention, accordingly to the methods of evaluation of these interactions. DEXA analysis is considered an useful tool to assess such phenomena, in order to analyse in a quantitative manner the local metabolic activity of the bone, and to evaluate over the time the integration between host bone and prosthetic components. The purpose of the present study is to report about a preliminary experience in the analysis of osseointegration processes of patients undergoing a primary Total Hip Arthroplasty (THA) or a revision Total Knee Arthroplasty (rTKA)...
May 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/27920811/the-use-of-routine-non-density-calibrated-clinical-computed-tomography-data-as-a-potentially-useful-screening-tool-for-identifying-patients-with-osteoporosis
#6
Christopher John Burke, Manjiri M Didolkar, Huiman X Barnhart, Emily N Vinson
OBJECTIVES: To evaluate whether lumbar vertebral body density CT attenuation values measured in Hounsfield Units (HUs) on routine Computed Tomography (CT) examinations can be reliably measured with limited variability, and to evaluate for a correlation between HUs and bone mineral density as measured by dual energy X-ray absorptiometry (DXA) scan. METHODS: Retrospective review of a total of 249 routine MDCT examinations, performed to measure HUs at the first non-rib bearing lumbar vertebral body on axial images, cross-referenced to the lateral scout image...
May 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/27915448/bone-mineral-content-and-areal-density-but-not-bone-area-predict-an-incident-fracture-risk-a-comparative-study-in-a-uk-prospective-cohort
#7
E M Curtis, N C Harvey, S D'Angelo, C S Cooper, K A Ward, P Taylor, G Pearson, C Cooper
: We studied a prospective UK cohort of women aged 20 to 80 years, assessed by dual-energy X-ray absorptiometry (DXA) at baseline. Bone mineral content (BMC) and areal bone mineral density (aBMD), but not bone area (BA), at femoral neck, lumbar spine and the whole body sites were similarly predictive of incident fractures. BACKGROUND: Low aBMD, measured by DXA, is a well-established risk factor for future fracture, but little is known about the performance characteristics of other DXA measures such as BA and BMC in fracture prediction...
December 2016: Archives of Osteoporosis
https://www.readbyqxmd.com/read/27913900/bone-mineral-density-of-extremities-is-associated-with-coronary-calcification-and-biopsy-verified-vascular-calcification-in-living-donor-renal-transplant-recipients
#8
Zhimin Chen, Jia Sun, Mathias Haarhaus, Peter Barany, Lars Wennberg, Jonaz Ripsweden, Torkel B Brismar, Bengt Lindholm, Annika Wernerson, Magnus Söderberg, Peter Stenvinkel, Abdul Rashid Qureshi
Chronic kidney disease (CKD) mineral and bone disorders (CKD-MBD) may lead to low bone mineral density (BMD) and vascular calcification (VC), but links to the latter are unclear. Here we investigated associations between BMD, coronary artery calcium (CAC) scores, and histological signs of VC in end-stage renal disease (ESRD) patients undergoing living-donor kidney transplantation (LD-Rtx). In 66 ESRD patients (median age 45 years, 68% males), BMD (by dual-energy X-ray absorptiometry, DXA), CAC score (by computed tomography, CT; n = 54), and degree of VC score (graded by histological examination of epigastric artery specimens collected at LD-Rtx; n = 55) were assessed at the time of LD-Rtx...
December 2, 2016: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/27908253/assessment-of-bone-quality-in-osteoporosis-treatment-with-bone-anabolic-agents-really-something-new
#9
Fabio Massimo Ulivieri, Renata Caudarella, Marzia Camisasca, Daniela Maria Cabrini, Ilaria Merli, Carmelo Messina, Luca Petruccio Piodi
Osteoporosis is a chronic pathologic condition, particularly of the elderly, in which a reduction of bone mineral density (BMD) weakens bone, leading to the so-called fragility fractures, most often of spine and femur. The gold standard exam for the quantitative measurement of BMD is the dual X-ray photon absorptiometry (DXA), a radiological method. However, a relevant number of fragility fractures occurs in the range of normal BMD values, meaning that also qualitative aspects of bone play a role, namely bone architecture and bone geometry...
December 1, 2016: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/27904420/role-of-the-whole-body-vibration-machine-in-the-prevention-and-management-of-osteoporosis-in-old-age-a-systematic-review
#10
REVIEW
Myint Swe, Biju Benjamin, Aye Aye Tun, Sandheep Sugathan
A literature search of related articles was carried out in electronic data sources. Initially, 276 randomised controlled trials related to the title were collected, after which 44 were selected using the keywords. Overlapping articles, articles with a study duration of less than six months, and studies involving young participants were removed from the list. The remaining 20 articles were checked for entitlement using the PEDro scale. A total of nine eligible articles with 1486 participants were analysed. Seven trials used dual-energy x-ray absorptiometry (DXA) to measure bone mineral density (BMD)...
September 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/27898642/manipulation-of-muscle-creatine-and-glycogen-changes-dxa-estimates-of-body-composition
#11
Julia L Bone, Megan L Ross, Kristyen A Tomcik, Nikki A Jeacocke, Will G Hopkins, Louise M Burke
: Standardising a dual x-ray absorptiometry (DXA) protocol is thought to provide a reliable measurement of body composition. PURPOSE: We investigated the effects of manipulating muscle glycogen and creatine content independently and additively on DXA estimates of lean mass. METHOD: Eighteen well-trained male cyclists undertook a parallel group application of creatine loading (n=9) (20 g/d for 5 d loading; 3 g/d maintenance) or placebo (n=9) with crossover application of glycogen loading (12 v 6 g/kg BM/d for 48 h) as part of a larger study involving a glycogen-depleting exercise protocol...
November 28, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27894941/one-year-of-abaloparatide-a-selective-peptide-activator-of-the-pth1-receptor-increased-bone-mass-and-strength-in-ovariectomized-rats
#12
Aurore Varela, Luc Chouinard, Elisabeth Lesage, Robert Guldberg, Susan Y Smith, Paul J Kostenuik, Gary Hattersley
Abaloparatide is a novel 34 amino acid peptide selected to be a potent and selective activator of the parathyroid hormone receptor 1 (PTHR1) signaling pathway. The effects of 12months of abaloparatide treatment on bone mass, bone strength and bone quality was assessed in osteopenic ovariectomized (OVX) rats. SD rats were subjected to OVX or sham surgery at 6months of age and left untreated for 3months to allow OVX-induced bone loss. Eighteen OVX rats were sacrificed after this bone depletion period, and the remaining OVX rats received daily s...
November 25, 2016: Bone
https://www.readbyqxmd.com/read/27893473/concurrent-training-promoted-sustained-anti-atherogenic-benefits-in-the-fasting-plasma-triacylglycerolemia-of-postmenopausal-women-at-1-year-follow-up
#13
Fabrício E Rossi, Tiego A Diniz, Ana Claudia S Fortaleza, Lucas M Neves, Malena R Picolo, Paula A Monteiro, Camila Buonani, Fábio S Lira, Ismael F Freitas
The aim of this study was to compare the effects of aerobic and concurrent training (aerobic plus strength training) on the lipid profiles of normotriacylglycerolemic and hypertriacylglycerolemic postmenopausal women and to verify whether the benefits of aerobic and concurrent training were sustained after 1 year. Total cholesterol, high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), Triacylglycerol (TAG) and glucose were assessed in 46 normotriacylglycerolemic (TAG<150 mg/dL) postmenopausal women divided into three groups: Aerobic Training (AT), Concurrent Training (CT) and a Control Group (CG)...
November 16, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27883171/frailty-in-postmenopausal-african-american-and-hispanic-hiv-infected-women
#14
P Young, J Shah, C Zhang, D C Ferris, I Colon, M Bucovsky, M Punyanitya, D J McMahon, E Shane, M T Yin
Studies suggest frailty occurs earlier in HIV-infected individuals, but data in postmenopausal HIV-infected women are lacking. We assessed the prevalence of frailty and association with anthropometric measures in HIV-infected and uninfected postmenopausal women. Fried's frailty phenotype was measured in HIV-infected and uninfected Hispanic and African American postmenopausal women participating in a study of bone metabolism; fat and lean mass were measured by whole body dual energy x-ray absorptiometry (DXA)...
2016: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/27881670/the-effect-of-alternate-day-caloric-restriction-on-the-metabolic-consequences-of-eight-days-bed-rest-in-healthy-lean-men-a-randomized-trial
#15
Nina Majlund Harder-Lauridsen, Signe Tellerup Nielsen, Sebastian Porsdam Mann, Mark Preben Lyngbæk, Fabiana Braga Benatti, Annika Reynberg Langkilde, Ian Law, Anne-Sophie Wedell-Neergaard, Carsten Thomsen, Kirsten Moller, Kristian Karstoft, Bente Klarlund Pedersen, Rikke Krogh-Madsen
BACKGROUND: Physical activity and alternate-day fasting/caloric restriction may both ameliorate aspects of the metabolic syndrome, such as insulin resistance, visceral fat mass accumulation, and cognitive impairment, by overlapping mechanisms. OBJECTIVE: To test the hypothesis that alternate-day caloric restriction (ADCR) with overall energy balance would reduce insulin resistance and accumulation of visceral fat, in addition to improving cognitive functions, after eight consecutive days in bed...
November 23, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27881458/dosage-of-estradiol-bone-and-body-composition-in-turner-syndrome-a-5-year-randomized-controlled-clinical-trial
#16
Line Cleemann, Kirsten Holm, Hanne Kobbernagel, Bent Kristensen, Sven Oluf Skouby, Andreas Emil Kryger Jensen, Claus Hojbjerg Gravholt
OBJECTIVE: Reduced bone mineral density (BMD) is seen in Turner syndrome (TS) with an increased risk of fractures, and body composition is characterized by increased body fat and decreased lean body mass. To evaluate the effect of two different doses of oral 17ß-estradiol in young TS women on bone mineral density (BMD), biochemical markers of bone turnover, and body composition with the hypothesis of a positive effect of the higher dose. DESIGN: A double-blind 5-year randomized controlled clinical trial...
November 23, 2016: European Journal of Endocrinology
https://www.readbyqxmd.com/read/27881116/concurrent-agreement-between-an-anthropometric-model-to-predict-thigh-volume-and-dual-energy-x-ray-absorptiometry-assessment-in-female-volleyball-players-aged-14-18-years
#17
Óscar M Tavares, João Valente-Dos-Santos, João P Duarte, Susana C Póvoas, Luís A Gobbo, Rômulo A Fernandes, Daniel A Marinho, José M Casanova, Lauren B Sherar, Daniel Courteix, Manuel J Coelho-E-Silva
BACKGROUND: A variety of performance outputs are strongly determined by lower limbs volume and composition in children and adolescents. The current study aimed to examine the validity of thigh volume (TV) estimated by anthropometry in late adolescent female volleyball players. Dual-energy X-ray absorptiometry (DXA) measures were used as the reference method. METHODS: Total and regional body composition was assessed with a Lunar DPX NT/Pro/MD+/Duo/Bravo scanner in a cross-sectional sample of 42 Portuguese female volleyball players aged 14-18 years (165...
November 24, 2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27879627/dietary-intake-body-composition-and-menstrual-cycle-changes-during-competition-preparation-and-recovery-in-a-drug-free-figure-competitor-a-case-study
#18
Tanya M Halliday, Jeremy P Loenneke, Brenda M Davy
Physique competitions are events in which competitors are judged on muscular appearance and symmetry. The purpose of this retrospective case study was to describe changes in dietary intake, body mass/composition, and the menstrual cycle during the 20-week competition preparation (PREP) and 20-week post competition recovery (REC) periods of a drug-free amateur female figure competitor (age = 26-27, BMI = 19.5 kg/m²). Dietary intake (via weighed food records) and body mass were assessed daily and averaged weekly...
November 20, 2016: Nutrients
https://www.readbyqxmd.com/read/27876008/physical-activity-and-metabolic-health-in-chronic-kidney-disease-a-cross-sectional-study
#19
Wilson Bowlby, Leila R Zelnick, Connor Henry, Jonathan Himmelfarb, Steven E Kahn, Bryan Kestenbaum, Cassianne Robinson-Cohen, Kristina M Utzschneider, Ian H de Boer
BACKGROUND: Patients with chronic kidney disease (CKD) are at high risk of progression to end stage renal disease and cardiovascular events. Physical activity may reduce these risks by improving metabolic health. We tested associations of physical activity with central components of metabolic health among people with moderate-severe non-diabetic CKD. METHODS: We performed a cross-sectional study of 47 people with CKD (estimated GFR <60 ml/min/1.73 m(2)) and 29 healthy control subjects...
November 22, 2016: BMC Nephrology
https://www.readbyqxmd.com/read/27875499/impact-of-acute-dietary-manipulations-on-dxa-and-bia-body-composition-estimates
#20
Grant M Tinsley, Flor E Morales, Jeffrey S Forsse, Peter W Grandjean
PURPOSE: To examine the effects of acute pre-assessment diets on body composition estimates obtained by dual-energy x-ray absorptiometry (DXA) and bioelectrical impedance analysis (BIA). METHODS: In a counterbalanced design, 48 males and females were provided with two one-day diets: high-carbohydrate diet (9 g CHO/kg) and very low-carbohydrate diet (1 to 1.5 g CHO/kg). For each condition, body composition was assessed in the morning after an overnight fast, in the afternoon after feeding, and the following morning after a second overnight fast...
November 21, 2016: Medicine and Science in Sports and Exercise
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