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https://www.readbyqxmd.com/read/28727760/detection-of-titin-fragments-in-urine-in-response-to-exercise-induced-muscle-damage
#1
Kazue Kanda, Jun Sakuma, Takayuki Akimoto, Yasuo Kawakami, Katsuhiko Suzuki
Many studies have attempted to determine the associations between blood biomarkers and exercise-induced muscle damage. However, poor correlations between the changes in biomarker levels and the magnitude of muscle symptoms have been reported. Recent advances in proteomic tools offer a strategy for the comprehensive analysis of protein expression, which can be used to identify biomarkers. Here, we used a proteomic analysis to identify urinary proteins that appear in response to a calf-raise exercise, including repetitive eccentric muscle contractions, and found that a titin (also known as connectin) N-terminal fragment molecule appears in the urine after eccentric exercise...
2017: PloS One
https://www.readbyqxmd.com/read/28725197/skeletal-muscle-remodeling-in-response-to-eccentric-vs-concentric-loading-morphological-molecular-and-metabolic-adaptations
#2
REVIEW
Martino V Franchi, Neil D Reeves, Marco V Narici
Skeletal muscle contracts either by shortening or lengthening (concentrically or eccentrically, respectively); however, the two contractions substantially differ from one another in terms of mechanisms of force generation, maximum force production and energy cost. It is generally known that eccentric actions generate greater force than isometric and concentric contractions and at a lower metabolic cost. Hence, by virtue of the greater mechanical loading involved in active lengthening, eccentric resistance training (ECC RT) is assumed to produce greater hypertrophy than concentric resistance training (CON RT)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28719765/beetroot-juice-is-more-beneficial-than-sodium-nitrate-for-attenuating-muscle-pain-after-strenuous-eccentric-bias-exercise
#3
Tom Clifford, Glyn Howatson, Daniel J West, Emma J Stevenson
The aim of this study was to compare the effects of beetroot juice (BTJ) and a nitrate only drink (sodium nitrate; SN) on indices of exercise-induced muscle damage (EIMD). Thirty recreationally active males consumed either BTJ (n=10), a nitrate matched SN drink (n=10) or an isocaloric placebo (PLA; n=10) immediately, 24 and 48 h after performing 100 drop jumps. To assess muscle damage, maximal isometric voluntary contractions (MIVC), countermovement jumps (CMJ), pressure-pain threshold (PPT), creatine kinase (CK) and high sensitivity C-reactive protein (hs-CRP) were measured pre, immediately post, 24, 48 and 72 h following the drop jumps...
July 18, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28717347/effect-of-eicosapentaenoic-acids-rich-fish-oil-supplementation-on-motor-nerve-function-after-eccentric-contractions
#4
Eisuke Ochi, Yosuke Tsuchiya, Kenichi Yanagimoto
BACKGROUND: This study investigated the effect of supplementation with fish oil rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on the M-wave latency of biceps brachii and muscle damage after a single session of maximal elbow flexor eccentric contractions (ECC). METHODS: Twenty-one men were completed the randomized, double-blind, placebo-controlled, and parallel-design study. The subjects were randomly assigned to the fish oil group (n = 10) or control group (n = 11)...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28716970/prolonged-force-depression-after-mechanically-demanding-contractions-is-largely-independent-of-ca-2-and-reactive-oxygen-species
#5
Sigitas Kamandulis, Felipe de Souza Leite, Andres Hernández, Abram Katz, Marius Brazaitis, Joseph D Bruton, Tomas Venckunas, Nerijus Masiulis, Dalia Mickeviciene, Nerijus Eimantas, Andrejus Subocius, Dilson E Rassier, Albertas Skurvydas, Niklas Ivarsson, Håkan Westerblad
Increased production of reactive oxygen/nitrogen species (ROS) and impaired cellular Ca(2+) handling are implicated in the prolonged low-frequency force depression (PLFFD) observed in skeletal muscle after both metabolically and mechanically demanding exercise. Metabolically demanding high-intensity exercise can induce PLFFD accompanied by ROS-dependent fragmentation of the sarcoplasmic reticulum Ca(2+) release channels, the ryanodine receptor (RyR)-1. We tested whether similar changes occur after mechanically demanding eccentric contractions...
July 17, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28716003/eccentric-versus-traditional-resistance-exercise-for-older-adult-fallers-in-the-community-a-randomized-trial-within-a-multi-component-fall-reduction-program
#6
Paul LaStayo, Robin Marcus, Leland Dibble, Bob Wong, Ginette Pepper
BACKGROUND: Addressing muscle deficits within a multi-component exercise fall reduction program is a priority, especially for the highest risk older adults, i.e., those who have fallen previously. Eccentric resistance exercise with its high-force producing potential, at a low energetic cost, may be ideally-suited to address muscle impairments in this population. The purpose of this study was to compare the effects of resistance exercise via negative, eccentrically-induced, work (RENEW) versus traditional (TRAD) resistance exercise on mobility, balance confidence, muscle power and cross sectional area, as well as the number of days high fall risk older adults survived without a fall event over a 1 year period...
July 17, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28714752/differences-in-the-load-velocity-profile-between-four-bench-press-variants
#7
Amador García-Ramos, Francisco Luis Pestaña-Melero, Alejandro Pérez-Castilla, Francisco Javier Rojas, Guy Gregory Haff
PURPOSE: This study aimed to compare the load-velocity relationship between four variants of the bench press (BP) exercise. METHODS: The full load-velocity relationship of 30 men were evaluated by means of an incremental loading test starting at 17 kg progressing to the individual one-repetition maximum (1RM) in four BP variants: concentric-only BP, concentric-only bench press throw (BPT), eccentric-concentric BP, and eccentric-concentric BPT. RESULTS: A strong and fairly linear relationship between mean velocity (MV) and %1RM was observed for the four BP variants (r(2) > 0...
July 17, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28713460/effects-of-an-elastic-hamstring-assistance-device-during-downhill-running
#8
Randy L Aldret, Brittany A Trahan, Greggory Davis, Brian Campbell, David M Bellar
The purpose of this study was to determine the appropriateness of using an elastic hamstring assistance device to reduce perceived levels of soreness, increase isometric strength, increase passive range of motion, and decrease biomarkers of muscle damage after eccentric exercise, specifically, downhill running This study was conducted in a university exercise physiology laboratory placing sixteen apparently healthy males (X = 21.6 ± 2.5 years) into two groups using a pre-test/post-test design. Pre-intervention measures taken included participants' body height, body mass, body fat, capillary blood samples, VO2max, isometric hamstring strength at 45 and 90 degrees of flexion and passive hamstring range of motion...
June 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28705613/aging-related-effects-of-bed-rest-followed-by-eccentric-exercise-rehabilitation-on-skeletal-muscle-macrophages-and-insulin-sensitivity
#9
Paul T Reidy, Catherine C Lindsay, Alec I McKenzie, Christopher S Fry, Mark A Supiano, Robin L Marcus, Paul C LaStayo, Micah J Drummond
The pro- and anti-inflammatory macrophages are associated with insulin sensitivity and skeletal muscle regeneration. Infiltrating macrophages in skeletal muscle during a period of physical inactivity and subsequent reloading/rehabilitation in older adults is unknown, but may provide insight into mechanisms related to the development of metabolic disease and changes in muscle cell size. The purpose of this study was to determine if skeletal muscle macrophage infiltration is modulated differently between young and older adults after bed rest and exercise rehabilitation and if these responses are related to muscle and insulin sensitivity changes...
July 10, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28704312/trunk-muscle-activation-in-the-back-and-hack-squat-at-the-same-relative-loads
#10
David R Clark, Michael I Lambert, Angus M Hunter
The hack squat (HS) is likely to produce a greater 1 repetition maximum (1RM) compared to the back squat (BS). This can be attributed to the support of the trunk during the HS compared to no support during BS. This support however, may compromise trunk muscle activation (TMA), therefore producing different training adaptations. Accordingly, the purpose of this study was to compare 1RM in BS and HS and TMA at 4 relative loads, 65, 75, 85 and 95% of maximal system mass. Ten males completed 3 test sessions:1) BS and HS 1RM, 2) HS & BS neuromuscular test familiarization, and, 3) Neuromuscular test for 3 reps at 4 loads for BS and HS...
July 12, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28693535/alfredson-versus-silbernagel-exercise-therapy-in-chronic-midportion-achilles-tendinopathy-study-protocol-for-a-randomized-controlled-trial
#11
Bas Habets, Robert E H van Cingel, Frank J G Backx, Bionka M A Huisstede
BACKGROUND: Midportion Achilles tendinopathy (AT) is a common overuse injury, usually requiring several months of rehabilitation. Exercise therapy of the ankle plantar flexors (i.e. tendon loading) is considered crucial during conservative rehabilitation. Alfredson's isolated eccentric and Silbernagel's combined concentric-eccentric exercise programs have both shown beneficial results, but it is unknown whether any of these programs is superior for use in clinical practice. Therefore, the primary objective of this study is to compare the effectiveness of both programs on clinical symptoms...
July 11, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28682936/effects-of-wearing-a-compression-garment-during-night-sleep-on-recovery-from-high-intensity-eccentric-concentric-quadriceps-muscle-fatigue
#12
Yohei Shimokochi, Satoshi Kuwano, Taichi Yamaguchi, Hiroyuki Abutani, Norihiro Shima
This study aimed to investigate the effects of wearing a compression garment (CG) during night sleep on muscle fatigue recovery after high-intensity eccentric and concentric knee extensor exercises. Seventeen college male students participated in two experimental sessions under CG and non-CG (NCG) wearing conditions. Before night sleep under CG or NCG wearing conditions, the subjects performed a fatiguing protocol consisting of 10 sets of 10 repetitions of maximal isokinetic eccentric and concentric knee extensor contractions, with 30-second rest intervals between the sets...
July 3, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28681170/accentuated-eccentric-loading-for-training-and-performance-a-review
#13
REVIEW
John P Wagle, Christopher B Taber, Aaron J Cunanan, Garett E Bingham, Kevin M Carroll, Brad H DeWeese, Kimitake Sato, Michael H Stone
Accentuated eccentric loading (AEL) prescribes eccentric load magnitude in excess of the concentric prescription using movements that require coupled eccentric and concentric actions, with minimal interruption to natural mechanics. This method has been theorized to potentiate concentric performance through higher eccentric loading and, thus, higher concentric force production. There is also evidence for favorable chronic adaptations, namely shifts to faster myosin heavy chain isoforms and changes in IIx-specific muscle cross-sectional area...
July 5, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28680370/effects-of-a-combined-protein-and-antioxidant-supplement-on-recovery-of-muscle-function-and-soreness-following-eccentric-exercise
#14
Stephen J Ives, Samuel Bloom, Alexs Matias, Noelle Morrow, Natalya Martins, Yookee Roh, Daniel Ebenstein, Gabriel O'Brien, Daniela Escudero, Kevin Brito, Leah Glickman, Scott Connelly, Paul J Arciero
BACKGROUND: An acute bout of eccentric contractions (ECC) cause muscle fiber damage, inflammation, impaired muscle function (MF) and muscle soreness (MS). Individually, protein (PRO) and antioxidant (AO) supplementation may improve some aspects of recovery from ECC, though have yet to be combined. We sought to determine if combined PRO and AO supplementation (PRO + AO) improves MS and MF following damaging ECC over PRO alone. METHODS: Sixty sedentary college-aged males participated in a randomized, single-blind, parallel design study of peak isometric torque (PIMT), peak isokinetic torque (PIKT), thigh circumference (TC), and muscle soreness (MS) of knee extensor muscles measured at baseline, immediately after and 1, 2, 6, and 24 h after completion of 100 maximal ECC...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28679397/local-coronary-wall-eccentricity-and-endothelial-function-are-closely-related-in-patients-with-atherosclerotic-coronary-artery-disease
#15
Allison G Hays, Micaela Iantorno, Michael Schär, Monica Mukherjee, Matthias Stuber, Gary Gerstenblith, Robert G Weiss
BACKGROUND: Coronary endothelial function (CEF) in patients with coronary artery disease (CAD) varies among coronary segments in a given patient. Because both coronary vessel wall eccentricity and coronary endothelial dysfunction are predictors of adverse outcomes, we hypothesized that local coronary endothelial dysfunction is associated with local coronary artery eccentricity. METHODS: We used 3 T coronary CMR to measure CEF as changes in coronary cross-sectional area (CSA) and coronary blood flow (CBF) during isometric handgrip exercise (IHE), a known endothelial-dependent stressor, in 29 patients with known CAD and 16 healthy subjects...
July 6, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28677940/effect-of-shoulder-position-on-triceps-brachii-heads-activity-in-dumbbell-elbow-extension-exercises
#16
Daniel de Souza Alves, Thiago T da Matta, Liliam F de Oliveira
BACKGROUND: Elbow extension exercises in different shoulder positions are selected to raise distinct effort levels among the triceps brachii heads. Because there are several triceps exercises, its choice is a big challenge on resistance training prescription. The present study aimed to compare the electromyographic signal of triceps brachii long and lateral heads among three different elbow ranges of motion (ROM) during two commonly prescribed elbow extension exercises: overhead dumbbell elbow extension (OD) and lying dumbbell elbow extension (LD)...
July 5, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28663378/factors-contributing-to-lower-metabolic-demand-of-eccentric-than-concentric-cycling
#17
Luis Penailillo, Anthony John Blazevich, Kazunori Nosaka
This study compared muscle-tendon behavior, muscle oxygenation and muscle activity between eccentric and concentric cycling exercise at the same work output to investigate why metabolic demand is lower during eccentric than concentric cycling. Eleven untrained men (27.1 ± 7.0 y) performed concentric cycling (CONC) and eccentric cycling (ECC) for 10 min (60 rpm) at 65% of the maximal concentric cycling power output (191 ± 45 W) four weeks apart. During cycling, oxygen consumption (VO2), heart rate (HR), vastus lateralis (VL) tissue total hemoglobin (tHb) and oxygenation index (TOI) were recorded, and muscle-tendon behavior was assessed using ultrasonography...
June 29, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28662123/effects-of-different-re-warm-up-activities-in-football-players-performance
#18
Eduardo Abade, Jaime Sampaio, Bruno Gonçalves, Jorge Baptista, Alberto Alves, João Viana
Warm up routines are commonly used to optimize football performance and prevent injuries. Yet, official pre-match protocols may require players to passively rest for approximately 10 to 15 minutes between the warm up and the beginning of the match. Therefore, the aim of this study was to explore the effect of different re-warm up activities on the physical performance of football players. Twenty-Two Portuguese elite under-19 football players participated in the study conducted during the competitive season...
2017: PloS One
https://www.readbyqxmd.com/read/28648554/the-isokinetic-rotator-cuff-strength-ratios-in-overhead-athletes-assessment-and-exercise-effect
#19
REVIEW
Kelly Berckmans, Annelies G Maenhout, Lien Matthijs, Louise Pieters, Birgit Castelein, Ann M Cools
OBJECTIVE: Muscle strength imbalance in the shoulder region can be considered as a predisposing factor in the development of movement dysfunctions, possibly leading to overuse injuries. Repetitive overhead throwing, performed in sports, may result in muscle imbalance between the external (ER) and internal (IR) rotators. Muscle strength measured with an isokinetic device, is reported as a concentric (CON) or eccentric (ECC) force. The balance between an agonist and an antagonist is mentioned as a ratio (CON/CON or ECC/CON)...
March 11, 2017: Physical Therapy in Sport
https://www.readbyqxmd.com/read/28641044/the-effects-of-short-versus-long-inter-set-rest-intervals-in-resistance-training-on-measures-of-muscle-hypertrophy-a-systematic-review
#20
Jozo Grgic, Bruno Lazinica, Pavle Mikulic, James W Krieger, Brad Jon Schoenfeld
Although the effects of short versus long inter-set rest intervals in resistance training on measures of muscle hypertrophy have been investigated in several studies, the findings are equivocal and the practical implications remain unclear. In an attempt to provide clarity on the topic, we performed a systematic literature search of PubMed/MEDLINE, Scopus, Web of Science, Cochrane Library, and Physiotherapy Evidence Database (PEDro) electronic databases. Six studies were found to have met the inclusion criteria: (a) an experimental trial published in an English-language peer-reviewed journal; (b) the study compared the use of short (≤60 s) to long (>60 s) inter-set rest intervals in a traditional dynamic resistance exercise using both concentric and eccentric muscle actions, with the only difference in resistance training among groups being the inter-set rest interval duration; (c) at least one method of measuring changes in muscle mass was used in the study; (d) the study lasted for a minimum of four weeks, employed a training frequency of ≥2 resistance training days per week, and (e) used human participants without known chronic disease or injury...
June 22, 2017: European Journal of Sport Science
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