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Wei Deng, Hui Li, Chunxi Zhang, Pengjie Wang
The influence of optical parameters on the performance of closed-loop optical voltage sensors (OVSs) based on Pockels effect is analyzed and a control algorithm is proposed to suppress the nonlinearity caused by the unideal parameters of optical devices for optimizing the detection precision of OVSs. First, a quantified model of the feedback phase demonstrates how the optical parameters of optical devices (including light source, polarizer, 45° fusion point, Faraday rotator and half-wave plate) result in the nonlinearity of closed-loop OVSs...
July 27, 2017: Sensors
Stefan Hajny, Christina Christoffersen
Hepatocytes, renal proximal tubule cells as well as the highly specialized endothelium of the blood brain barrier (BBB) express and secrete apolipoprotein M (apoM). ApoM is a typical lipocalin containing a hydrophobic binding pocket predominantly carrying Sphingosine-1-Phosphate (S1P). The small signaling molecule S1P is associated with several physiological as well as pathological pathways whereas the role of apoM is less explored. Hepatic apoM acts as a chaperone to transport S1P through the circulation and kidney derived apoM seems to play a role in S1P recovery to prevent urinal loss...
July 27, 2017: International Journal of Molecular Sciences
Yohan Lee, Sun-Je Kim, Hyeonsoo Park, Byoungho Lee
Electromagnetic metamaterials (MMs) and metasurfaces (MSs) are artificial media and surfaces with subwavelength separations of meta-atoms designed for anomalous manipulations of light properties. Owing to large scattering cross-sections of metallic/dielectric meta-atoms, it is possible to not only localize strong electromagnetic fields in deep subwavelength volume but also decompose and analyze incident light signal with ultracompact setup using MMs and MSs. Hence, by probing resonant spectral responses from extremely boosted interactions between analyte layer and optical MMs or MSs, sensing the variation of refractive index has been a popular and practical application in the field of photonics...
July 27, 2017: Sensors
Maximilian Wolf, Astrid Herrmann, Andreas Hirsch, Dirk M Guldi
Porphyrin arrays, which consist of three peripheral ZnPs and a central H2P - all rigidly linked to each other -serve as light harvesting antennas as well as electron donors and are flexibly coupled to an electron accepting C60 to realize the unidirectional flow of i) excited state energy from the ZnPs at the periphery to the H2P, ii) electrons to C60, and iii) holes to H2P and, subsequently, to ZnP. Dynamics following photoexcitation are elucidated by time resolved transient absorption measurements on the femto-, pico, nano-, and microsecond time scales and are examined by multiwavelength as well as target analyses...
July 27, 2017: Journal of the American Chemical Society
Yao-Hui Sun, Yuxin Sun, Kan Zhu, Brian Reid, Xing Gao, Bruce W Draper, Min Zhao, Alex Mogilner
Stationary symmetrical fish keratocyte cells break symmetry and become motile spontaneously but slowly. We found that applying electric field (EF) accelerates the polarization by an order of magnitude. While spontaneously polarized cells move persistently for hours, the EF-induced polarity is lost in a majority of cells when the EF is switched off. However, if the EF is applied for a long time and then switched off, the majority of cell move stably. Myosin inhibition abolishes spontaneous polarization, but does not slow down EF-induced polarization, and after the EF is turned off, motility does not stop; however, the cell movements are erratic...
July 27, 2017: Journal of Cellular Physiology
Shiyu Long, Fei Lin, Changguang Yao, Dongmei Cui
The polymerization of a new polar diene-based monomer 2-(2-methylidenebut-3-enyl)furan (MBEF) without masking is achieved by using the bis(phosphino)carbazoleide-ligated yttrium (Y) alkyl complex upon the activation of [Ph3 C][B(C6 F5 )4 ]. Under mild conditions, the polymerizations under the monomer-to-Y ratios ranging from 100:1 to 500:1 perform fluently in high yields. The afforded polydienes bearing pendant terminal furan groups have high cis-1,4-regularity up to 98.6% and molecular weights close to the theoretic values and narrow polymer dispersity index(PDI) (1...
July 27, 2017: Macromolecular Rapid Communications
E Troja, V M Lipunov, C G Mundell, N R Butler, A M Watson, S Kobayashi, S B Cenko, F E Marshall, R Ricci, A Fruchter, M H Wieringa, E S Gorbovskoy, V Kornilov, A Kutyrev, W H Lee, V Toy, N V Tyurina, N M Budnev, D A H Buckley, J González, O Gress, A Horesh, M I Panasyuk, J X Prochaska, E Ramirez-Ruiz, R Rebolo Lopez, M G Richer, C Román-Zúñiga, M Serra-Ricart, V Yurkov, N Gehrels
Newly formed black holes of stellar mass launch collimated outflows (jets) of ionized matter that approach the speed of light. These outflows power prompt, brief and intense flashes of γ-rays known as γ-ray bursts (GRBs), followed by longer-lived afterglow radiation that is detected across the electromagnetic spectrum. Measuring the polarization of the observed GRB radiation provides a direct probe of the magnetic fields in the collimated jets. Rapid-response polarimetric observations of newly discovered bursts have probed the initial afterglow phase, and show that, minutes after the prompt emission has ended, the degree of linear polarization can be as high as 30 per cent-consistent with the idea that a stable, globally ordered magnetic field permeates the jet at large distances from the central source...
July 26, 2017: Nature
Bozhena Sergeyevna Komarova, Alexey G Gerbst, Anastasiia M Finogenova, Andrey S Dmitrenok, Yury Evgenievich Tsvetkov, Nikolay E Nifantiev
The strength of 1,3-syn-diaxial repulsion was evaluated for main types of protecting groups (alkyl, silyl and acyl) usually used in carbohydrate chemistry. As molecular probes for this study, derivatives of isopropyl 2-O-benzyl-4,6-O-benzylidene-α-D-idopyranoside bearing allyl, acetyl and tert-butyldiphenylsilyl (TBDPS) protecting groups at O-3 were prepared from p-methoxyphenyl D-galactopyranoside. The equilibrium between (O)S2 and (4)C1 conformations in these compounds was investigated using (3)JH,H and (3)JС,H coupling constants that were determined from 1D (1)H-NMR and 2D J-resolved HMBC spectra in various solvents...
July 27, 2017: Journal of Organic Chemistry
Fadime Ozdemir-Kocak, Kamil Isik, Salih Saricaoglu, Hayrettin Saygin, Kadriye Inan-Bektas, Demet Cetin, Kiymet Guven, Nevzat Sahin
A Kribbella strain FSN23(T) was isolated from soil sample which was collected from Caygoren Dam lakeside located in Sındırgı, Turkey. The isolate was investigated using a polyphasic approach consisting of numeric, chemotaxonomic and molecular analysis. The isolate indicated chemotaxonomic, morphological and phylogenetic properties associated with members of the genus Kribbella. Phylogenetic analysis based on the 16S rRNA sequence of the strain demonstrated that the strain forms a subclade with K. aluminosa HKI 0478(T) and K...
July 26, 2017: Archives of Microbiology
Md Arafat Mahmud, Naveen Kumar Elumalai, Mushfika Baishakhi Upama, Dian Wang, Vinicius R Gonçales, Matthew Wright, Cheng Xu, Faiazul Haque, Ashraf Uddin
Here we report a small molecule oxidant 2,3,5,6-tetrafluoro-7,7,8,8-tetracyano-quinodimethane (F4TCNQ) doped, low cost 2',7'-bis(bis(4-methoxyphenyl)amino)spiro[cyclopenta[2,1-b:3,4-b']dithiophene-4,9'-fluorene] (FDT) hole transporting layer (HTL) for efficient mixed organic cation based MA0.6FA0.4PbI3 (MA = methyl ammonium, FA = formamidinium) perovskite solar cells (PSCs), fabricated via a highly reproducible controlled nucleation assisted restricted volume solvent annealing method, having full temperature compatibility with flexible substrates...
July 27, 2017: Physical Chemistry Chemical Physics: PCCP
Md Kamrul Hassan, Nur Mohammad Nahid, Ali Newaz Bahar, Mohammad Maksudur Rahman Bhuiyan, Md Abdullah-Al-Shafi, Kawsar Ahmed
Quantum-dot cellular automata (QCA) is a developing nanotechnology, which seems to be a good candidate to replace the conventional complementary metal-oxide-semiconductor (CMOS) technology. In this article, we present the dataset of average output polarization (AOP) for basic reversible logic gates presented in Ali Newaz et al. (2016) [1]. QCADesigner 2.0.3 has been employed to analysis the AOP of reversible gates at different temperature levels in Kelvin (K) unit.
August 2017: Data in Brief
Fatemeh Forouzanfar, Azar Hosseini, Mohammad Sadegh Amiri, Hassan Rakhshandeh
OBJECTIVE: Sleeplessness is the most common sleep disorder. In this study the hypnotic effect of the hydro-alcoholic extract (HAE) of Perovskia abrotanoides Karel. and its water fraction (WF), ethyl acetate fraction (EAF) and n-butanol fraction (NBF) were studied in mice. MATERIALS AND METHODS: The test compounds were administered intraperitoneally to mice 30 min before the administration of sodium pentobarbital (30 mg/kg.). Moreover, the influence of flumazenil on the hypnotic effect of the extracts was evaluated...
May 2017: Avicenna Journal of Phytomedicine
Gaafar Ragab, Mohsen Elshahaly, Thomas Bardin
Gout is a picturesque presentation of uric acid disturbance. It is the most well understood and described type of arthritis. Its epidemiology is studied. New insights into the pathophysiology of hyperuricemia and gouty arthritis; acute and chronic allow for an even better understanding of the disease. The role of genetic predisposition is becoming more evident. The clinical picture of gout is divided into asymptomatic hyperuricemia, acute gouty arthritis, intercritical period, and chronic tophaceous gout. Diagnosis is based on laboratory and radiological features...
September 2017: Journal of Advanced Research
Manuel Izquierdo, Piero Torelli, Jun Fujii, Giancarlo Panaccione, Ivana Vobornik, Giorgio Rossi, Fausto Sirotti
Carbon (C) surface segregation from bulk stabilizes the Fe(0 18 1) vicinal surface by forming a c(3[Formula: see text] × [Formula: see text] reconstruction with C zig-zag chains oriented at 45° with respect to the iron surface steps. The iron surface electronic states as measured by high resolution ARPES at normal emission with polarized synchrotron radiation split in two peaks that follow distinct energy dispersion curves. One peak follows the dispersion of the carbon superstructure and is photoexcited only when the polarization vector is parallel to the steps, the second peak disperses similarly to the pristine Fe(0 0 1) surface...
July 26, 2017: Scientific Reports
Xiaobing Shang, Laurens Meeus, Dieter Cuypers, Herbert De Smet
Optical beam deflectors based on the combination of cholesteric liquid crystals and polymer micro gratings are reported. Dual frequency cholesteric liquid crystal (DFCh-LC) is adopted to accelerate the switching from the homeotropic state back to the planar state. Polarization independent beam steering components are realized whose transmission versus the polarizing angle only varies 4.4% and 2.6% for the planar state and the homeotropic state, respectively. A response time of 451 ms is achieved for DFCh-LC-grating beam deflectors, which is fast compared to other nematic LC beam steerers with similar LC thickness...
July 26, 2017: Scientific Reports
Luminita M Hrib, Lucian Pintilie, Marin Alexe
Measurements of the magnetocapacitance effect in epitaxial La0.7Sr0.3MnO3/Pb(Zr0.2Ti0.8)O3/La0.7Sr0.3MnO3 heterostructures have been performed using a quasi-static method. Through capacitance-voltage measurements carried out under variable magnetic field it has been found that the magneto-capacitance depends on the orientation of the ferroelectric polarization. The value of magneto-capacitance can be as high as 1% in the voltage range near the ferroelectric coercive field. This has been attributed to a variation of the apparent built-in voltage of the PZT-LSMO Schottky barriers on applied magnetic field...
July 26, 2017: Scientific Reports
Takashi Maehara
  IgG4-related disease (IgG4-RD) is a chronic inflammatory disease characterized by tumescent lesions with characteristic storiform fibrosis, obliterative phlebitis and a marked lymphoplasmacytic infiltrate that includes a large number of IgG4 positive plasma cells. It's widely accepted that rituximab-mediated B cell depletion therapy is effective for this disease. Important mechanistic insights correlated with the pathogenesis of IgG4-RD have been gradually disclosed from studies of patients treated by B cell depletion...
2017: Nihon Rinshō Men'eki Gakkai Kaishi, Japanese Journal of Clinical Immunology
Anthony J Blaszczyk, Bo Wang, Alexey Silakov, Jackson V Ho, Squire J Booker
TsrM catalyzes the methylation of C2 in Ltryptophan (Trp). This reaction is the first step in the biosynthesis of the quinaldic acid moiety of the thiopeptide antibiotic thiostrepton, which exhibits potent activity against Gram-positive pathogens. TsrM is a member of the radical S-adenosylmethionine (SAM) superfamily of enzymes, but does not catalyze formation of 5'-deoxyadenosin-5'-yl or any other SAM-derived radical. In addition to a [4Fe-4S] cluster, TsrM contains a cobalamin cofactor that serves as an intermediate methyl carrier in its reaction...
July 26, 2017: Journal of Biological Chemistry
Christian Schwartz, Adnan R Khan, Achilleas Floudas, Sean P Saunders, Emily Hams, Hans-Reimer Rodewald, Andrew N J McKenzie, Padraic G Fallon
Group 2 innate lymphoid cells (ILC2s) are important effector cells driving the initiation of type 2 immune responses leading to adaptive T helper 2 (Th2) immunity. Here we show that ILC2s dynamically express the checkpoint inhibitor molecule PD-L1 during type 2 pulmonary responses. Surprisingly, PD-L1:PD-1 interaction between ILC2s and CD4(+) T cells did not inhibit the T cell response, but PD-L1-expressing ILC2s stimulated increased expression of GATA3 and production of IL-13 by Th2 cells both in vitro and in vivo...
July 26, 2017: Journal of Experimental Medicine
HooiCheng Lim, Chun-Ying Yu, Tzuu-Shuh Jou
Establishment of apical-basal polarity, through correct targeting of polarity determinants to distinct domains of the plasma membrane, is a fundamental process for the development of functioning epithelial tubules. Here we report that galectin (Gal)-8 regulates apical-basal polarity of Madin-Darby canine kidney (MDCK) cells via apical targeting of 135-kDa glycoprotein (Gp135). Gal-8 interacts with newly synthesized Gp135 in a glycan-dependent manner. Gal-8 knockdown induces aberrant lumens at the lateral domain and mistargeting of Gp135 to this structure, thus disrupting the kidney epithelial polarity of MDCK cells, which organize lumens at the apical surface...
July 26, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
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