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https://www.readbyqxmd.com/read/28647482/isolation-and-structural-characterization-of-dihydrobenzofuran-congeners-of-licochalcone-a
#1
Charlotte Simmler, David C Lankin, Dejan Nikolić, Richard B van Breemen, Guido F Pauli
In an effort to explore the residual complexity of naturally occurring chalcones from the roots of Glycyrrhiza inflata (Fabaceae), two new licochalcone A (LicA) derivatives were isolated as trace metabolites from enriched fractions. Both constituents contain a dihydrofuran moiety linked to carbons C-4 and C-5 of the retrochalcone core. Compound 1 (LicAF1) represents a new chemical entity, whereas compound 2 (LicAF2) has previously been reported as a Lewis acid catalyzed rearrangement of LicA. Evaluation of chirality revealed that both dihydrofuran derivatives existed as a mixture of R and S enantiomers...
June 21, 2017: Fitoterapia
https://www.readbyqxmd.com/read/28644007/cyclotides-as-tools-in-chemical-biology
#2
Simon J de Veer, Joachim Weidmann, David J Craik
Among the various molecules that plants produce for defense against pests and pathogens, cyclotides stand out as exceptionally stable and structurally unique. These ribosomally synthesized peptides are around 30 amino acids in size, and are stabilized by a head-to-tail cyclic peptide backbone and three disulfide bonds that form a cystine knot. They occur in certain plants of the Rubiaceae, Violaceae, Cucurbitaceae, Fabaceae, and Solanaceae families, with an individual plant producing up to hundreds of different cyclotides...
June 23, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28642702/amorpha-fruticosa-a-noxious-invasive-alien-plant-in-europe-or-a-medicinal-plant-against-metabolic-disease
#3
REVIEW
Ekaterina Kozuharova, Adam Matkowski, Dorota Woźniak, Rumiana Simeonova, Zheko Naychov, Clemens Malainer, Andrei Mocan, Seyed M Nabavi, Atanas G Atanasov
Amorpha fruticosa L. (Fabaceae) is a shrub native to North America which has been cultivated mainly for its ornamental features, honey plant value and protective properties against soil erosion. It is registered amongst the most noxious invasive species in Europe. However, a growing body of scientific literature also points to the therapeutic potential of its chemical constituents. Due to the fact that A. fruticosa is an aggressive invasive species, it can provide an abundant and cheap resource of plant chemical constituents which can be utilized for therapeutic purposes...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28640753/mechanism-of-antihypertensive-effect-of-mucuna-pruriens-l-seed-extract-and-its-isolated-compounds
#4
Mohammad Yaseen Khan, Vimal Kumar
Background In the search of safe and effective lead molecules from natural sources, Mucuna pruriens (MP) L. (Fabaceae) seeds were utilized for exploring the antihypertensive potential. Traditionally, it is used as diuretic and hypotensive. Methods Bioassay-guided fractions were utilized for the isolation of active compounds by column chromatography. IC50 value, enzyme kinetics and inhibition mechanism were determined. In vivo time and dose-dependent hypotensive study followed by changes in mean arterial pressure (MAP) induced by angiotensin I (3 nmol/kg), angiotensin II (3 nmol/kg), and bradykinin (10 nmol/kg) in anesthetized rats was done...
June 21, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28638879/traditional-knowledge-of-medicinal-plants-in-tribes-of-tripura-in-northeast-india
#5
Maria Debbarma, Nazir A Pala, Munesh Kumar, Rainer W Bussmann
BACKGROUND: The present study was carried out in Mandwi area and its outskirts of Tripura district of tribal areas Autonomous district council to document the available ethno-medicinal plants and their traditional application among Mandwi tribes. METHODOLOGY: Field explorations were carried out during the months of March-June 2013. The ethno-medicinal survey was conducted particularly with Tripuri tribe in Mandai area, with the help of local medicine men, locally known as bhoidho (Tripuri)...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28626426/potential-of-central-eastern-and-western-africa-medicinal-plants-for-cancer-therapy-spotlight-on-resistant-cells-and-molecular-targets
#6
REVIEW
Armelle T Mbaveng, Victor Kuete, Thomas Efferth
Cancer remains a major health hurdle worldwide and has moved from the third leading cause of death in the year 1990 to second place after cardiovascular disease since 2013. Chemotherapy is one of the most widely used treatment modes; however, its efficiency is limited due to the resistance of cancer cells to cytotoxic agents. The present overview deals with the potential of the flora of Central, Eastern and Western African (CEWA) regions as resource for anticancer drug discovery. It also reviews the molecular targets of phytochemicals of these plants such as ABC transporters, namely P-glycoprotein (P-gp), multi drug-resistance-related proteins (MRPs), breast cancer resistance protein (BCRP, ABCG2) as well as the epidermal growth factor receptor (EGFR/ErbB-1/HER1), human tumor suppressor protein p53, caspases, mitochondria, angiogenesis, and components of MAP kinase signaling pathways...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28620371/variation-in-soil-microbial-community-structure-associated-with-different-legume-species-is-greater-than-that-associated-with-different-grass-species
#7
Yang Zhou, Honghui Zhu, Shenglei Fu, Qing Yao
Plants are the essential factors shaping soil microbial community (SMC) structure. When most studies focus on the difference in the SMC structure associated different plant species, the variation in the SMC structure associated with phylogenetically close species is less investigated. Legume (Fabaceae) and grass (Poaceae) are functionally important plant groups; however, their influences on the SMC structure are seldom compared, and the variation in the SMC structure among legume or grass species is largely unknown...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28610391/systematics-biogeography-and-host-plant-relationships-of-the-neotropical-jumping-plant-louse-genus-russelliana-hemiptera-psylloidea
#8
Liliya Serbina, Daniel Burckhardt
The Neotropical genus Russelliana (Psyllidae: Aphalaroidinae) is revised and its phylogenetic, host-plant and biogeographical relationships are discussed. Twenty-four species are described as new, bringing the number of known species to 43. An identification key is provided for the adults. A phylogenetic analysis of 26 morphological characters resulted in 54 most parsimonious trees. The consensus tree is well resolved at the base but poorly at the crown. Most Russelliana species are monophagous or oligophagous with the exception of R...
May 12, 2017: Zootaxa
https://www.readbyqxmd.com/read/28610300/new-species-of-leaf-mining-nepticulidae-lepidoptera-from-the-neotropical-and-ando-patagonian-regions-with-new-data-on-host-plants
#9
Jonas R Stonis, Andrius Remeikis, Arūnas Diškus, Nick Megoran
The paper treats fifteen species of leaf-mining pygmy moths (Insecta, Lepidoptera, Nepticulidae) discovered in the Neotropics (British Virgin Islands, Belize, Costa Rica, Venezuela, and Ecuador), and Ando-Patagonian region (Argentina and Chile). Except for two species, all belong to Stigmella Schrank. Twelve species are new, and are named and described in the current paper: Stigmella apicibrunella Diškus & Stonis, sp. nov.; S. decora Diškus & Stonis, sp. nov.; S. unicaudata Remeikis & Stonis, sp. nov.; S...
May 26, 2017: Zootaxa
https://www.readbyqxmd.com/read/28609938/illustrated-review-of-the-leaf-mining-nepticulidae-of-the-central-andes%C3%A2-peru-and-bolivia
#10
Jonas R Stonis, Arūnas Diškus, Andrius Remeikis, Ole Karsholt, Nixon Cumbicus Torres
We review forty-five species of Nepticulidae (Lepidoptera) based on an analysis of samples collected in the central Andean region of Peru and Bolivia. Thirteen of these species are new to science, and are named and described here: Stigmella paracosma Remeikis & Stonis, sp. nov., S. expressa Remeikis & Stonis, sp. nov., S. acalyphae Diškus & Stonis, sp. nov., S. lepida Diškus & Stonis, sp. nov., S. misera Diškus & Stonis, sp. nov., S. inca Diškus & Stonis, sp. nov., S. eiffeli Diškus & Stonis, sp. nov., S...
April 24, 2017: Zootaxa
https://www.readbyqxmd.com/read/28577435/aryl-benzofuran-derivatives-from-the-stem-bark-of-calpocalyx-dinklagei-attenuate-inflammation
#11
Deccaux W F G Kapche, Nadège M Lekane, Seda S Kulabas, Hande Ipek, Tugba T Tok, Bonaventure T Ngadjui, Ibrahim Demirtas, Tugba B Tumer
Calpocalyx dinklagei Harms (Fabaceae) is a tropical medicinal tree, which is indigenous to Western Africa. A phytochemical study of this local plant species from its stem bark has led to the isolation of two previously undescribed aryl benzofuran derivatives, named dinklagein A and B, together with eight known compounds. Their chemical structures were elucidated by use of extensive spectroscopic methods (IR, HREI-MS and 1D and 2D NMR). Among all isolates, dinklagein A displayed remarkably potent inhibitory activity against the production of nitric oxide (NO) in the lipopolysaccharide (LPS) induced RAW264...
May 31, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28562783/occurrence-of-allorhogas-sp-hymenoptera-braconidae-doryctinae-associated-with-galls-on-seeds-of-inga-vera-fabaceae-in-brazil
#12
T Morales-Silva, S L Modesto-Zampieron
No abstract text is available yet for this article.
May 25, 2017: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/28545665/astragaloside%C3%A2-against-cardiac-fibrosis-by-inhibiting-trpm7-channel
#13
Jun Lu, Quan-Yi Wang, Yang Zhou, Xiao-Chun Lu, Yong-Hui Liu, Yan Wu, Qiao Guo, Yun-Tian Ma, Yi-Qun Tang
BACKGROUND: Astragaloside Ⅳ (ASG-Ⅳ, (Fig. 1) is the most active component of Chinese sp. Astragalus membranaceus Bunge (Fabaceae) that has showed antioxidant, antiapoptotic and antiviral activities among others. It is reported to play an important role in cardiac fibrosis (CF), but the mechanism remains unclear. PURPOSE: To investigate the mechanism of ASG-Ⅳ on inhibiting myocardial fibrosis induced by hypoxia. STUDY DESIGN: We studied the relationship between anti-fibrotic effect of ASG-Ⅳ and transient receptor potential cation channel, subfamily M, member 7 (TRPM7) by in vivo and in vitro experiments...
July 1, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28544154/floral-nectar-of-the-obligate-outcrossing-canavalia-gladiata-jacq-dc-fabaceae-contains-only-one-predominant-protein-a-class-iii-acidic-chitinase
#14
Xue-Long Ma, Richard I Milne, Hong-Xia Zhou, Jiang-Yu Fang, Hong-Guang Zha
Floral nectar can affect the fitness of insect-pollinated plants, through both attraction and manipulation of pollinators. Self-incompatible insect-pollinated plants receive more insect visits than their self-compatible relatives, and the nectar of such species might face more risk to be infested by the pathogens carried by pollinators than self-compatible plants. Proteins in nectar (nectarins) play an important role in the protection of nectar, but little is known regarding nectarins in self-incompatible species...
May 20, 2017: Plant Biology
https://www.readbyqxmd.com/read/28539717/caspase-mediated-apoptotic-effects-of-ebenus-boissieri-barbey-extracts-on-human-cervical-cancer-cell-line-hela
#15
Ece Simsek, Nilufer Imir, Esra Arslan Aydemir, Ramazan Suleyman Gokturk, Erdem Yesilada, Kayahan Fiskin
BACKGROUND: Ebenus boissieri Barbey is an Antalya, Turkey-endemic plant belonging to Fabaceae family. The aerial parts and the roots of E. boissieri Barbey were used in this study. OBJECTIVE: In the present study, we have examined the apoptotic effects of hydroalcoholic extracts of E. boissieri Barbey in human cervical cancer cell line HeLa. MATERIALS AND METHODS: To determine the cytotoxic effect, cells were treated with various concentrations of extracts for 24, 48, and 72 h incubation periods...
April 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28536059/current-state-of-knowledge-on-the-traditional-uses-phytochemistry-and-pharmacology-of-the-genus-hymenaea
#16
REVIEW
Pone Kamdem Boniface, Sabrina Baptista Ferreira, Carlos Roland Kaiser
ETHNOPHARMACOLOGICAL RELEVANCE: Plants of the genus Hymenaea (Fabaceae) are used in South American and Asian traditional medicines to treat a multitude of disorders, like cough, diarrhea, dysentery, intestinal colic, pulmonary weakness, asthma, anemia, sore throat, and for the treatment of kidney problems, viral related disorders, chronic cystitis, bronchitis, and bladder infections. Some Hymenaea species are also used as vermifuge, and for the treatment of arthritis, and inflammation conditions...
May 21, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28529836/chloroplast-and-mitochondrial-microsatellites-for-millettia-pinnata-fabaceae-and-cross-amplification-in-related-species
#17
Yanling Wang, Hongxian Xie, Yi Yang, Yelin Huang, Jianwu Wang, Fengxiao Tan
PREMISE OF THE STUDY: Chloroplast and mitochondrial microsatellites were identified to study the population genetics of Millettia pinnata (Fabaceae). METHODS AND RESULTS: Based on publicly available plastid genome sequence data of M. pinnata, 42 primer pairs were developed, of which 17 displayed polymorphisms across 89 individuals from four populations. For chloroplast loci, two to six alleles were recovered and the unbiased haploid diversity per locus ranged from 0...
May 2017: Applications in Plant Sciences
https://www.readbyqxmd.com/read/28526725/phylogeography-and-genetic-structure-of-endemic-acmispon-argophyllus-and-a-dendroideus-fabaceae-across-the-california-channel-islands
#18
Lisa E Wallace, Gregory L Wheeler, Mitchell E McGlaughlin, Gerald Bresowar, Kaius Helenurm
PREMISE OF THE STUDY: Taxa inhabiting the California Channel Islands exhibit variation in their degree of isolation, but few studies have considered patterns across the entire archipelago. We studied phylogeography of insular Acmispon argophyllus and A. dendroideus to determine whether infraspecific taxa are genetically divergent and to elucidate patterns of diversification across these islands. METHODS: DNA sequences were collected from nuclear (ADH) and plastid genomes (rpL16, ndhA, psbD-trnT) from >450 samples on the Channel Islands and California...
May 19, 2017: American Journal of Botany
https://www.readbyqxmd.com/read/28515782/ecotypic-differentiation-under-farmers-selection-molecular-insights-into-the-domestication-of-pachyrhizus-rich-ex-dc-fabaceae-in-the-peruvian-andes
#19
Marc Delêtre, Beatriz Soengas, Prem Jai Vidaurre, Rosa Isela Meneses, Octavio Delgado Vásquez, Isabel Oré Balbín, Monica Santayana, Bettina Heider, Marten Sørensen
Understanding the distribution of crop genetic diversity in relation to environmental factors can give insights into the eco-evolutionary processes involved in plant domestication. Yam beans (Pachyrhizus Rich. ex DC.) are leguminous crops native to South and Central America that are grown for their tuberous roots but are seed-propagated. Using a landscape genetic approach, we examined correlations between environmental factors and phylogeographic patterns of genetic diversity in Pachyrhizus landrace populations...
June 2017: Evolutionary Applications
https://www.readbyqxmd.com/read/28512462/de-novo-transcriptome-profiling-of-flowers-flower-pedicels-and-pods-of-lupinus-luteus-yellow-lupine-reveals-complex-expression-changes-during-organ-abscission
#20
Paulina Glazinska, Waldemar Wojciechowski, Milena Kulasek, Wojciech Glinkowski, Katarzyna Marciniak, Natalia Klajn, Jacek Kesy, Jan Kopcewicz
Yellow lupine (Lupinus luteus L., Taper c.), a member of the legume family (Fabaceae L.), has an enormous practical importance. Its excessive flower and pod abscission represents an economic drawback, as proper flower and seed formation and development is crucial for the plant's productivity. Generative organ detachment takes place at the basis of the pedicels, within a specialized group of cells collectively known as the abscission zone (AZ). During plant growth these cells become competent to respond to specific signals that trigger separation and lead to the abolition of cell wall adhesion...
2017: Frontiers in Plant Science
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