Vivek Vijay, Susan P Mollan, James L Mitchell, Edward Bilton, Zerin Alimajstorovic, Keira A Markey, Anthony Fong, Jessica K Walker, Hannah S Lyons, Andreas Yiangou, Georgios Tsermoulas, Kristian Brock, Alexandra J Sinclair
Importance: There is an unmet need for noninvasive biomarkers of intracranial pressure (ICP), which manifests as papilledema that can be quantified by optical coherence tomography (OCT) imaging. Objective: To determine whether OCT of the optic nerve head in papilledema could act as a surrogate measure of ICP. Design, Setting, and Participants: This longitudinal cohort study used data collected from 3 randomized clinical trials that were conducted between April 1, 2014, and August 1, 2019...
December 1, 2020: JAMA Ophthalmology