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https://www.readbyqxmd.com/read/29029009/the-effect-of-physical-activity-and-cardiorespiratory-fitness-on-all-cause-mortality-in-hong-kong-chinese-older-people
#1
Zhihui Lu, Jean Woo, Timothy Kwok
Background: It is unclear whether physical activity (PA) could predict all-cause mortality independently of cardiorespiratory fitness, and there are relatively few studies evaluating the combined effect of PA and cardiorespiratory fitness on mortality. Methods: We invited 1,242 Chinese older adults aged 69 to 94 years from the MrOs and MsOs cohort (Hong Kong) study for a 7-year follow-up. PA was measured by the Physical Activity Scale of the Elderly (PASE). Cardiorespiratory fitness, expressed as maximal oxygen uptake (VO2max), was assessed by performing symptom-limited maximal exercise testing on an electrically braked bicycle ergometer and 6-meter walk test...
September 19, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28985325/home-based-telerehabilitation-in-older-patients-with-chronic-obstructive-pulmonary-disease-and-heart-failure-a-randomised-controlled-trial
#2
Palmira Bernocchi, Michele Vitacca, Maria Teresa La Rovere, Maurizio Volterrani, Tiziana Galli, Doriana Baratti, Mara Paneroni, Giuseppe Campolongo, Barbara Sposato, Simonetta Scalvini
Background: chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) frequently coexist in older people, reducing patients' quality of life (QoL) and increasing morbidity and mortality. Objective: we studied the feasibility and efficacy of an integrated telerehabilitation home-based programme (Telereab-HBP), 4 months long, in patients with combined COPD and CHF. The primary outcome was exercise tolerance evaluated at the 6-min walk test (6MWT)...
August 30, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28980277/straightforward-protocol-for-gel-free-proteomic-analysis-of-adipose-tissue
#3
Yvonne Pasing, Armin Schniers, Terkel Hansen
After conducting systematic and quantitative comparisons of different sample preparation techniques regarding their capability to efficiently and reproducibly recover proteins from biopsies, we present here our superior protocol for extracting proteins from low amounts of adipose tissue. Adipose tissue as a matrix in bottom-up proteomics is challenging due to the extremely high lipid content.The lysis buffer utilized contains the detergent sodium deoxycholate, which does not impair the activity of trypsin and therefore enables direct digestion without detergent removal steps...
October 5, 2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28972111/author-response-prolonged-sleep-duration-as-a-marker-of-early-neurodegeneration-predicting-incident-dementia
#4
Matthew P Pase, Andrew J Westwood, Alexa Beiser, Nikita Jain, Charles DeCarli, Jayandra J Himali, Sanford H Auerbach, Sudha Seshadri
No abstract text is available yet for this article.
October 3, 2017: Neurology
https://www.readbyqxmd.com/read/28972109/author-response-prolonged-sleep-duration-as-a-marker-of-early-neurodegeneration-predicting-incident-dementia
#5
Matthew P Pase, Sudha Seshadri
No abstract text is available yet for this article.
October 3, 2017: Neurology
https://www.readbyqxmd.com/read/28962167/effect-of-l-arginine-supplementation-on-the-hepatic-phosphatidylinositol-3-kinase-signaling-pathway-and-gluconeogenic-enzymes-in-early-intrauterine-growth-restricted-rats
#6
Kaiju Luo, Pingyang Chen, Suping Li, Wen Li, Mingfeng He, Tao Wang, Juncao Chen
The present study aimed to investigate the response of the phosphatidylinositol 3-kinase (PI3K) signaling pathway and gluconeogenic enzymes in intrauterine growth-restricted rats to dietary L-arginine (L-Arg) supplementation during the lactation period early in life. Pregnant Sprague-Dawley rats were randomly divided into a control group (CON), an intrauterine growth restriction group (IUGR) and an L-Arg group (LA). The pregnant rats in the CON group were fed a 21% protein diet, and those in the IUGR and LA groups were fed a 10% low protein diet, and all rats were fed a 21% protein diet after delivery...
September 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28917522/does-physical-activity-change-following-hip-and-knee-replacement-matched-case-control-study-evaluating-physical-activity-scale-for-the-elderly-data-from-the-osteoarthritis-initiative
#7
T O Smith, M Mansfield, J Dainty, G Hilton, C J V Mann, C M Sackley
OBJECTIVES: To determine whether physical activity measured using the Physical Activity Scale for the Elderly (PASE), changes during the initial 24 months post-total hip (THR) or knee replacement (TKR), and how this compares to a matched non-arthroplasty cohort. DESIGN: Case-controlled study analysis of a prospectively collected dataset. SETTING: USA community-based. PARTICIPANTS: 116 people post-THR, 105 people post-TKR compared to 663 people who had not undergone THR or TKR, or had hip or knee osteoarthritis...
September 13, 2017: Physiotherapy
https://www.readbyqxmd.com/read/28915820/item-response-modeling-a-psychometric-assessment-of-the-children-s-fruit-vegetable-water-and-physical-activity-self-efficacy-scales-among-chinese-children
#8
Jing-Jing Wang, Tzu-An Chen, Tom Baranowski, Patrick W C Lau
BACKGROUND: This study aimed to evaluate the psychometric properties of four self-efficacy scales (i.e., self-efficacy for fruit (FSE), vegetable (VSE), and water (WSE) intakes, and physical activity (PASE)) and to investigate their differences in item functioning across sex, age, and body weight status groups using item response modeling (IRM) and differential item functioning (DIF). METHODS: Four self-efficacy scales were administrated to 763 Hong Kong Chinese children (55...
September 16, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28862943/inter-relations-of-orthostatic-blood-pressure-change-aortic-stiffness-and-brain-structure-and-function-in-young-adults
#9
Leroy L Cooper, Jayandra J Himali, Alyssa Torjesen, Connie W Tsao, Alexa Beiser, Naomi M Hamburg, Charles DeCarli, Ramachandran S Vasan, Sudha Seshadri, Matthew P Pase, Gary F Mitchell
BACKGROUND: Relations of orthostatic change in blood pressure with brain structure and function have not been studied thoroughly, particularly in younger, healthier individuals. Elucidation of factors that contribute to early changes in brain integrity may lead to development of interventions that delay or prevent cognitive impairment. METHODS AND RESULTS: In a sample of the Framingham Heart Study Third Generation (N=2119; 53% women; mean age±SD, 47±8 years), we assessed orthostatic change in mean arterial pressure (MAP), aortic stiffness (carotid-femoral pulse wave velocity), neuropsychological function, and markers of subclinical brain injury on magnetic resonance imaging...
August 17, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28856821/the-proteome-of-ulcerative-colitis-in-colon-biopsies-from-adults-optimized-sample-preparation-and-comparison-with-healthy-controls
#10
Armin Schniers, Endre Anderssen, Christopher Graham Fenton, Rasmus Goll, Yvonne Pasing, Ruth Hracky Paulssen, Jon Florholmen, Terkel Hansen
PURPOSE: The purpose of the study was to optimize the sample preparation and to further use an improved sample preparation to identify proteome differences between inflamed ulcerative colitis tissue from untreated adults and healthy controls. EXPERIMENTAL DESIGN: To optimize the sample preparation, we studied the effect of adding different detergents to a urea containing lysis buffer for a Lys-C/trypsin tandem digestion. With the optimized method, we prepared clinical samples from six ulcerative colitis patients and six healthy controls and analysed them by LC-MS/MS...
August 30, 2017: Proteomics. Clinical Applications
https://www.readbyqxmd.com/read/28835407/sleep-architecture-and-the-risk-of-incident-dementia-in-the-community
#11
Matthew P Pase, Jayandra J Himali, Natalie A Grima, Alexa S Beiser, Claudia L Satizabal, Hugo J Aparicio, Robert J Thomas, Daniel J Gottlieb, Sandford H Auerbach, Sudha Seshadri
OBJECTIVE: Sleep disturbance is common in dementia, although it is unclear whether differences in sleep architecture precede dementia onset. We examined the associations between sleep architecture and the prospective risk of incident dementia in the community-based Framingham Heart Study (FHS). METHODS: Our sample comprised a subset of 321 FHS Offspring participants who participated in the Sleep Heart Health Study between 1995 and 1998 and who were aged over 60 years at the time of sleep assessment (mean age 67 ± 5 years, 50% male)...
September 19, 2017: Neurology
https://www.readbyqxmd.com/read/28820755/sleep-complications-following-traumatic-brain-injury
#12
Natalie A Grima, Jennie L Ponsford, Matthew P Pase
PURPOSE OF REVIEW: Recent research has provided extensive characterization as to the frequency and nature of sleep disturbances following traumatic brain injury (TBI). This review summarizes the current state of knowledge and proposes future directions for research. RECENT FINDINGS: Complaints of sleep disturbance are common following TBI, and objective assessments of sleep largely corroborate these complaints. Sleep is often disturbed in the acute phase postinjury and can persist for decades, with the prevalence of sleep disorders higher in patients with TBI as compared with the general population...
August 17, 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/28805508/corrigendum-to-effectiveness-of-a-multidimensional-web-based-intervention-program-to-change-brazilian-health-practitioners-attitudes-toward-the-lesbian-gay-bisexual-and-transgender-population
#13
Angelo Brandelli Costa, Paola Fagundes Pase, Eric Seger de Camargo, Camila Guaranha, Adriano Henrique Caetano, Daniel Kveller, Heitor Thomé da Rosa Filho, Ramiro Figueiredo Catelan, Silvia Helena Koller, Henrique Caetano Nardi
Corrigendum to: J Health Psychol DOI 10.1177/1359105316628748 Unfortunately, the online published article has an error in one of the analyses. On page 365, fifth paragraph, the corrected statistical report is (Δ 1.66, 95% CI [3.32, .01], t (305) = -1.98, p<.05), not (Δ 1.66, 95% CI [3.32, .01], t (305) = -1.66, p <.05). In spite of this correction, there is no change in the direction of the test and therefore in the interpretation of this result.
June 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28800755/the-influence-of-3%C3%A2-months-of-physical-exercises-and-verbal-stimulation-on-functional-efficiency-and-use-of-free-time-in-an-older-population-under-institutional-care-study-protocol-for-a-randomized-controlled-trial
#14
Agnieszka Wiśniowska-Szurlej, Agnieszka Ćwirlej-Sozańska, Anna Wilmowska-Pietruszyńska, Natalia Milewska, Bernard Sozański
BACKGROUND: In recent years, there has been a significant change in the demographics of developed countries, including an increase in the number of older people. This aging population and the associated need for medical care and assistance places great strain on health care systems worldwide. In older populations, improved knowledge and understanding of the relationship between moderate exercise and health might result in greater motivation to engage in such activity; thus improving the overall health of this population...
August 11, 2017: Trials
https://www.readbyqxmd.com/read/28761295/the-clinical-profile-of-patients-with-psoriasis-in-korea-a-nationwide-cross-sectional-study-epi-psode
#15
Hae Jun Song, Chul Jong Park, Tae Yoon Kim, Yong Beom Choe, Seok-Jong Lee, Nack In Kim, Jae We Cho, Jie Hyun Jeon, Min Soo Jang, Jai Il Youn, Myung Hwa Kim, Joonsoo Park, Ki Ho Kim, Byung Soo Kim, Sang Woong Youn, Joo-Heung Lee, Min-Geol Lee, Sung Ku Ahn, Young Ho Won, Seok Kweon Yun, Bong Seok Shin, Seong Jun Seo, Ji Yeoun Lee, Kwang Joong Kim, Young Suck Ro, Youngdoe Kim, Dae Young Yu, Jee-Ho Choi
BACKGROUND: Psoriasis is an immune-mediated, chronic inflammatory disease affecting multiple aspects of patients' lives. Its epidemiology varies regionally; however, nationwide epidemiologic data on psoriasis depicting profile of Korean patients has not been available to date. OBJECTIVE: To understand nationwide epidemiologic characteristics and clinical features of adult patients with psoriasis visited university hospitals in Korea. METHODS: This multicenter, non-interventional, cross-sectional study recruited 1,278 adult patients with psoriasis across 25 centers in Korea in 2013...
August 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28746497/revealing-an-hiv-diagnosis-for-children-and-adolescents-subsidy-for-the-practice-of-care
#16
Bruna Pase Zanon, Cristiane Cardoso de Paula, Stela Maris de Mello Padoin
Objective: To collectively build a guide for following-up on HIV diagnosis disclosure to children and adolescents in a specialized service. Method: Convergent-care research approach with observation triangulation, interview and groups, conducted from May to June 2015 with seven health professionals in a pediatric outpatient clinic for infectious diseases. Thematic content analysis was developed. Results: The discussion of understanding the disclosure, its triggers, actors involved, used strategies, and limits and possibilities listed by the professionals subsidized the construction of a guide to be applied in the stages: analyzing children's questions and curiosities; evaluating their cognitive ability; discussing the reasons to reveal; listing the professionals involved on follow-up process; including family; developing strategies for disclosure...
July 20, 2017: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/28713520/decisional-balance-and-self-efficacy-of-physical-activity-among-the-elderly-in-rasht-in-2013-based-on-the-transtheoretical-model
#17
Seddigheh Abbaspour, Rabiollah Farmanbar, Fateme Njafi, Arezoo Mohamadkhani Ghiasvand, Leila Dehghankar
BACKGROUND: Regular physical activity has been considered as health promotion, and identifying different effective psycho-social variables on physical has proven to be essential. OBJECTIVE: To identify the relationship between decisional balance and self-efficacy in physical activities using the transtheoretical model in the members of a retirement center in Rasht, Guillen. METHODS: A descriptive cross-sectional study was conducted in 2013 by using convenient sampling on 262 elderly people who are the members of retirement centers in Rasht...
May 2017: Electronic Physician
https://www.readbyqxmd.com/read/28699662/effects-of-calycosin-against-high-fat-diet-induced-nonalcoholic-fatty-liver-disease-in-mice
#18
Xingping Duan, Qiang Meng, Changyuan Wang, Zhihao Liu, Huijun Sun, Xiaokui Huo, Pengyuan Sun, Xiaodong Ma, Jinyong Peng, Kexin Liu
BACKGROUND AND AIM: Nonalcoholic fatty liver disease (NAFLD) has become a major health concern worldwide. The present study was designed to investigate the effects of calycosin against high fat diet (HFD)-induced NAFLD in mice. METHODS: C57BL/6J male mice were fed with HFD to induce NAFLD model and treated with or without calycosin for 12 weeks. The levels of ALT, AST, insulin and adiponectin were measured using biochemical methods. H&E staining and Oil Red O staining were used to determine the liver histopathology changes and measure the degree of lipid accumulation respectively...
July 12, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28655652/-p-clphse-2-stimulates-carbohydrate-metabolism-and-reverses-the-metabolic-alterations-induced-by-high-fructose-load-in-rats
#19
Caroline B Quines, Suzan G Rosa, Pietro M Chagas, Daniela Velasquez, Vinicius C Prado, Cristina W Nogueira
The modern life leads to excess consumption of food rich in fructose; however, the long-term changes in carbohydrate and lipid metabolism could lead to metabolic dysfunction in humans. The present study evaluated the in vitro insulin-mimetic action of p-chloro-diphenyl diselenide (p-ClPhSe)2. The second aim of this study was to investigate if (p-ClPhSe)2 reverses metabolic dysfunction induced by fructose load in Wistar rats. The insulin-mimetic action of (p-ClPhSe)2 at concentrations of 50 and 100 μM was determined in slices of rat skeletal muscle...
September 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28618742/the-turkish-version-of-the-physical-activity-scale-for-the-elderly-pase-its-cultural-adaptation-validation-and-reliability
#20
Ender Ayvat, Muhammed Kilinç, Nuray Kirdi
BACKGROUND/AIM: This study aimed to describe the cultural adaptation of the Turkish Physical Activity Scale for the Elderly (PASE) and to examine the reliability and validity of the scale in older Turkish adults. MATERIALS AND METHODS: Eighty elderly people were recruited for the study. The assessments included the PASE, the International Physical Activity Questionnaire (IPAQ), the Short Physical Performance Battery and Short Form-36 Quality of Life Questionnaire (SF-36), and the Mini Mental State Test...
June 12, 2017: Turkish Journal of Medical Sciences
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