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https://www.readbyqxmd.com/read/29593384/cross-cultural-adaptation-and-validation-of-the-arabic-version-of-the-physical-activity-scale-for-the-elderly-among-community-dwelling-older-adults-in-saudi-arabia
#1
Ayidh M Alqarni, Vishal Vennu, Sulaiman A Alshammari, Saad M Bindawas
Purpose: Older adults are the fastest growing population group worldwide. Regular physical activity (PA) is reported to reduce the risk of health conditions and improve personal well-being. Few validated instruments can be used to measure the PA levels among older adults in Saudi Arabia. The Physical Activity Scale for the Elderly (PASE) is used worldwide for evaluating the PA levels of the elderly in epidemiological studies. However, this scale has not been translated into Arabic. This study aimed to cross-culturally adapt the PASE into Arabic language and evaluate its reliability and validity among community-dwelling older adults in Saudi Arabia...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29529273/the-association-between-trajectories-of-physical-activity-and-all-cause-and-cause-specific-mortality
#2
Deepika Laddu, Neeta Parimi, Jane A Cauley, Peggy M Cawthon, Kristine E Ensrud, Eric Orwoll, Marcia Stefanick, Lisa Langsetmo
Background: The benefits of physical activity (PA) for health have primarily been evaluated during midlife. Whether patterns of change in late-life PA associate with overall and cause-specific mortality remains unclear. Methods: We examined the association between PA trajectories and subsequent mortality among 3,767 men aged ≥ 65 years. Men self-reported PA using the Physical Activity Scale for the Elderly scale (PASE) at up to 4 time points from 2000 through 2009 (Year 7); mortality was assessed over an average of 7...
February 26, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29507137/author-response-sleep-architecture-and-the-risk-of-incident-dementia-in-the-community
#3
Matthew P Pase, Jayandra J Himali, Natalie A Grima, Alexa S Beiser, Claudia L Satizabal, Hugo J Aparicio, Robert J Thomas, Daniel J Gottlieb, Sanford H Auerbach, Sudha Seshadri
No abstract text is available yet for this article.
March 6, 2018: Neurology
https://www.readbyqxmd.com/read/29499895/-characteristics-present-in-secondary-school-students-who-do-not-smoke-and-who-have-no-intention-to-smoke
#4
Marta Lima-Serrano, José Manuel Martínez-Montilla, Ana Magdalena Vargas-Martínez, José Antonio Zafra-Agea, Joaquín Salvador Lima-Rodríguez
OBJECTIVE: To know the variables present in primary and secondary school students who do not smoke or intend to smoke from a positive health model. METHODS: Cross-sectional study with 482 students from Andalusia and Catalonia using a validated questionnaire (ESFA and PASE project). Binary logistic regression analysis was performed. RESULTS: Those who did not intend to smoke viewed smoking unfavourably and had high self-efficacy (p <0.001)...
February 27, 2018: Gaceta Sanitaria
https://www.readbyqxmd.com/read/29487746/impact-of-exercise-counseling-on-physical-function-in-chronic-kidney-disease-an-observational-study
#5
Clara J Bohm, Leroy J Storsley, Brett M Hiebert, Serena Nelko, Navdeep Tangri, Lawrence J Cheskin, Mara A McAdams-DeMarco, Claudio Rigatto
Background: Individuals with chronic kidney disease (CKD) have low levels of physical activity and physical function. Although guidelines endorse exercise counseling for individuals with CKD, it is not yet part of routine care. Objective: We investigated the effect of attending a real-life exercise counseling clinic (ECC) on physical function in individuals with CKD. Design: Retrospective analysis of prospectively collected observational data with quasi-experimental design...
2018: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/29474961/the-presence-of-glutamate-residues-on-the-pas-sequence-of-the-stimuli-sensitive-nano-ferritin-improves-in-vivo-biodistribution-and-mitoxantrone-encapsulation-homogeneity
#6
Elisabetta Falvo, Francesca Malagrinò, Alessandro Arcovito, Francesco Fazi, Gianni Colotti, Elisa Tremante, Patrizio Di Micco, Aldo Braca, Roberta Opri, Alessandro Giuffrè, Giulio Fracasso, Pierpaolo Ceci
A genetically engineered human ferritin heavy chain (HFt)-based construct has been recently shown by our group to efficiently entrap and deliver doxorubicin to cancer cells. This construct, named HFt-MP-PAS, contained a tumor-selective sequence (MP) responsive to proteolytic cleavage by tumor proteases (MMPs), located between each HFt subunit and an outer shielding polypeptide sequence rich in proline (P), serine (S) and alanine (A) residues (PAS). HFt-MP-PAS displayed excellent therapeutic efficacy in xenogenic pancreatic and head and neck cancer models in vivo, leading to a significant increase in overall animal survivals...
February 20, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29454336/change-in-physical-activity-level-and-clinical-outcomes-in-older-adults-with-knee-pain-a-secondary-analysis-from-a-randomised-controlled-trial
#7
Jonathan G Quicke, Nadine E Foster, Peter R Croft, Reuben O Ogollah, Melanie A Holden
BACKGROUND: Exercise interventions improve clinical outcomes of pain and function in adults with knee pain due to osteoarthritis and higher levels of physical activity are associated with lower severity of pain and higher levels of physical functioning in older adults with knee osteoarthritis in cross-sectional studies. However, to date no studies have investigated if change in physical activity level during exercise interventions can explain clinical outcomes of pain and function. This study aimed to investigate if change in physical activity during exercise interventions is associated with future pain and physical function in older adults with knee pain...
February 17, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29430733/the-relationship-between-clinical-characteristics-including-presence-of-exposed-lesions-and-health-related-quality-of-life-hrqol-in-patients-with-psoriasis-analysis-from-the-nationwide-epidemiologic-study-for-psoriasis-in-korea-epi-psode-study
#8
S W Youn, J-H Lee, D Y Yu, Y Kim, B S Kim, S J Seo, Y B Choe, S-K Yun, J Park, N I Kim, C W Choi, J I Youn, S-J Lee, M-G Lee, K J Kim, C J Park, Y S Ro, H J Song, B S Shin, S K Ahn, J Y Lee, Y H Won, M S Jang, K H Kim, M H Kim, T Y Kim, J H Choi
BACKGROUND: Psychological aspect and quality of life should be considered in treating patients with psoriasis. OBJECTIVE: We sought to ascertain which clinical characteristics including presence of exposed lesions are associated with impairment of health-related quality of life (HRQoL) in patients with psoriasis. METHODS: The EPI-PSODE study was a nationwide, multicenter, cross-sectional study conducted in Korea that included 1,260 adult patients with psoriasis...
February 11, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29317381/using-social-media-for-the-promotion-of-education-and-consultation-in-adolescents-who-have-undergone-kidney-transplant-protocol-for-a-randomized-control-trial
#9
Claudiana Pase, Andréia Dias Mathias, Clotilde Druck Garcia, Clarissa Garcia Rodrigues
BACKGROUND: Falling ill represents a traumatic experience especially in adolescence, since in addition to the moments of ambiguity and contradictions that this period brings, there is coping with the disease. Renal transplantation provides a better quality of life but the dependence on dialysis is replaced by the greater responsibility of self-care. With advances in technology, contemporary communication methods are a strategic mechanism for the approximation of the adolescent and the multiprofessional team...
January 9, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29305881/liver-carbohydrates-metabolism-a-new-islet-neogenesis-associated-protein-peptide-ingap-pp-target
#10
Hernán Gonzalo Villagarcía, Carolina Lisi Román, María Cecilia Castro, Luisa Arbeláez González, María Teresa Ronco, Daniel Eleazar Francés, María Laura Massa, Bárbara Maiztegui, Luis Emilio Flores, Juan José Gagliardino, Flavio Francini
Islet-Neogenesis Associated Protein-Pentadecapeptide (INGAP-PP) increases β-cell mass and enhances glucose and amino acids-induced insulin secretion. Our aim was to demonstrate its effect on liver metabolism. For that purpose, adult male Wistar rats were injected twice-daily (10 days) with saline solution or INGAP-PP (250 μg). Thereafter, serum glucose, triglyceride and insulin levels were measured and homeostasis model assessment (HOMA-IR) and hepatic insulin sensitivity (HIS) were determined. Liver glucokinase and glucose-6-phosphatase (G-6-Pase) expression and activity, phosphoenolpyruvate carboxykinase (PEPCK) expression, phosphofructokinase-2 (PFK-2) protein content, P-Akt/Akt and glycogen synthase kinase-3β (P-GSK3/GSK3) protein ratios and glycogen deposit were also determined...
March 2018: Peptides
https://www.readbyqxmd.com/read/29304778/inflammation-and-glucose-homeostasis-are-associated-with-specific-structural-features-among-adults-without-knee-osteoarthritis-a-cross-sectional-study-from-the-osteoarthritis-initiative
#11
Alina C Stout, Mary F Barbe, Charles B Eaton, Mamta Amin, Fatimah Al-Eid, Lori Lyn Price, Bing Lu, Grace H Lo, Ming Zhang, Jincheng Pang, Timothy E McAlindon, Jeffrey B Driban
BACKGROUND: Greater age and body mass index are strong risk factors for osteoarthritis (OA). Older and overweight individuals may be more susceptible to OA because these factors alter tissue turnover in menisci, articular cartilage, and bone via altered glucose homeostasis and inflammation. Understanding the role of inflammation and glucose homeostasis on structural features of early-stage OA may help identify therapeutic targets to delay or prevent the onset of OA among subsets of adults with these features...
January 5, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29299789/hiv-related-healthcare-needs-and-access-barriers-for-brazilian-transgender-and-gender-diverse-people
#12
Angelo Brandelli Costa, Anna Martha Vaitses Fontanari, Ramiro Figueiredo Catelan, Karine Schwarz, Juliana Ledur Stucky, Heitor Tome da Rosa Filho, Paola Fagundes Pase, Daniel Augusto Mori Gagliotti, Alexandre Saadeh, Maria Inês Rodrigues Lobato, Henrique Caetano Nardi, Silvia Helena Koller
The aim of this study is to investigate HIV-related healthcare needs and access barriers for Brazilian transgender and gender diverse people. Data were collected from gender identity clinics and the questionnaire was also made available on the Internet. Out of the 543 participants-62.1% (n = 337) transgender women, 28.7 (n = 156) transgender men and 9.2% (n = 50) gender diverse people, 63.7% had been tested at least once in their lives. The prevalence of self-reported HIV-positive status among transgender women was 16...
January 3, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29288178/pilot-for-the-australian-breast-device-registry-abdr-a-national-opt-out-clinical-quality-registry-for-breast-device-surgery
#13
Ingrid Hopper, Renee L Best, John J McNeil, Catherine M Mulvany, Colin C M Moore, Elisabeth Elder, Marie Pase, Rodney D Cooter, Sue M Evans
PURPOSE: To establish a pilot clinical quality registry (CQR) to monitor the quality of care and device performance for breast device surgery in Australia. PARTICIPANTS: All patients having breast device surgery from contributing hospitals in Australia. A literature review was performed which identified quality indicators for breast device surgery. FINDINGS TO DATE: A pilot CQR was established in 2011 to capture prospective data on breast device surgery...
December 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/29209877/effects-of-fish-and-grape-seed-oils-as-core-of-haloperidol-loaded-nanocapsules-on-oral-dyskinesia-in-rats
#14
Dalila Moter Benvegnú, Katiane Roversi, Raquel Cristine Silva Barcelos, Fabíola Trevizol, Camila Simonetti Pase, Hecson Jesser Segat, Verônica Tironi Dias, Ana Luiza Savian, Bruna Lopes Piccoli, Jaqueline Piccolo, Carlos Severo Dutra-Filho, Tatiana Emanuelli, Cristiane de Bona da Silva, Ruy Carlos Ruver Beck, Marilise Escobar Burger
Haloperidol is a widely used antipsychotic, despite the severe motor side effects associated with its chronic use. This study was carried out to compare oral dyskinesia induced by different formulations of haloperidol-loaded nanocapsules containing caprylic/capric triglycerides, fish oil or grape seed oil (GSO) as core, as well as free haloperidol. Haloperidol-loaded lipid-core nanocapsules formulations were prepared, physicochemical characterized and administered (0.5 mg kg-1 -ip) to rats for 28 days. Oral dyskinesia was evaluated acutely and subchronically and after that cell viability and free radical generation in cortex and substantia nigra...
February 2018: Neurochemical Research
https://www.readbyqxmd.com/read/29197532/vascular-risk-factor-burden-and-new-onset-depression-in-the-community
#15
Shayna Adams, Sarah Conner, Jayandra J Himali, Alexa Beiser, Ramachandran S Vasan, Sudha Seshadri, Matthew P Pase
Depression is associated with an increased likelihood of cardiac events and stroke. We hypothesized that the vascular risk factor burden might itself predispose to both cardiovascular events and depression. Therefore, we examined whether aggregate scores of vascular risk factor burden were associated with the new-onset of depression in the community. We studied 2023 depression- and dementia-free Framingham Heart Study (Framingham, USA) Offspring participants who attended both examination cycles 7 (1998-2001) and 8 (2005-2008)...
November 29, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29192470/the-stripp-questionnaire-screening-tool-for-rheumatologic-investigation-in-psoriatic-patients-as-a-new-tool-for-the-diagnosis-of-early-psoriatic-arthritis
#16
Martina Burlando, Emanuele Cozzani, Irene Schiavetti, Stefano Cicchelli, Marco Repetto, Gianluca Rossotto, Enrico Scaparro, Aurora Parodi
BACKGROUND: Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis in up to one third of psoriatic patients. Clinically it's characterized from an insidious onset. To help clinicians screen for PsA, several screening tools have been developed. The psoriatic arthritis screening and evaluation questionnaire (PASE) is one of the most used in the Psocare units. The sensibility of PASE is of 83% with a cut off of 47 or greater. The aim of our study is to create an Italian self-administered questionnaire, lighter than the PASE, able to identify patients who need a rheumatologic consultation...
November 30, 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29178359/elevated-luteinizing-hormone-despite-normal-testosterone-levels-in-older-men-natural-history-risk-factors-and-clinical-features
#17
Robert J A H Eendebak, Tomas Ahern, Agnieszka Swiecicka, Stephen R Pye, Terence W O'Neill, Gyorgy Bartfai, Felipe F Casanueva, Mario Maggi, Gianni Forti, Aleksander Giwercman, Thang S Han, Jolanta Słowikowska-Hilczer, Michael E J Lean, Margus Punab, Neil Pendleton, Brian G Keevil, Dirk Vanderschueren, Martin K Rutter, Gindo Tampubolon, Royston Goodacre, Ilpo T Huhtaniemi, Frederick C W Wu
OBJECTIVE: Elevated luteinizing hormone (LH) with normal testosterone (T) suggests compensated dysregulation of the gonadal axis. We describe the natural history, risk factors and clinical parameters associated with the development of high LH (HLH, LH >9.4 U/L) in ageing men with normal T (T ≥ 10.5 nmol/L). DESIGN, PATIENTS AND MEASUREMENTS: We conducted a 4.3-year prospective observational study of 3369 community-dwelling European men aged 40-79 years...
March 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29164375/patient-reported-physical-activity-and-the-association-with-health-related-quality-of-life-in-head-and-neck-cancer-survivors
#18
Annette J van Nieuwenhuizen, Laurien M Buffart, Cornelia F van Uden-Kraan, Lilly-Ann van der Velden, Martin Lacko, Johannes Brug, C René Leemans, Irma M Verdonck-de Leeuw
PURPOSE: This study aimed to assess patient-reported levels of physical activity (PA) and its associations with health-related quality of life (HRQoL) adjusted for important demographic, lifestyle-related, and clinical factors, among head and neck (HNC) survivors. METHODS: This cross-sectional study included 116 HNC survivors. PA was assessed with the Physical Activity Scale for the Elderly (PASE) and HRQoL with the EORTC-QLQ-C30 and EORTC-HN35. Associations were studied using univariable and multivariable regression analyses...
November 21, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29134006/-cecidonius-pampeanus-gen-et-sp-n-an-overlooked-and-rare-new-gall-inducing-micromoth-associated-with-schinus-in-southern-brazil-lepidoptera-cecidosidae
#19
Gilson R P Moreira, Rodrigo P Eltz, Ramoim B Pase, Gabriela T Silva, Sérgio A L Bordignon, Wolfram Mey, Gislene L Gonçalves
Galls induced by the larval stage of cecidosids (Lepidoptera: Cecidosidae) are complex, multi-trophic systems, still poorly studied. They may be associated with other insect feeding guilds, including inquilines, kleptoparasites, cecidophages, parasitoids, and predators. By causing death of the gall inducer early in life and altering the gall phenotype, inquilines may lead to misidentification of the true gall inducers. Here, we describe through light and scanning electron microscopy Cecidonius pampeanus , a new genus and species of cecidosid moth, from the Pampa biome, south Brazil...
2017: ZooKeys
https://www.readbyqxmd.com/read/29029009/the-effect-of-physical-activity-and-cardiorespiratory-fitness-on-all-cause-mortality-in-hong-kong-chinese-older-people
#20
Zhihui Lu, Jean Woo, Timothy Kwok
Background: It is unclear whether physical activity (PA) could predict all-cause mortality independently of cardiorespiratory fitness, and there are relatively few studies evaluating the combined effect of PA and cardiorespiratory fitness on mortality. Methods: We invited 1,242 Chinese older adults aged 69 to 94 years from the MrOs and MsOs cohort (Hong Kong) study for a 7-year follow-up. PA was measured by the Physical Activity Scale of the Elderly (PASE). Cardiorespiratory fitness, expressed as maximal oxygen uptake (VO2max), was assessed by performing symptom-limited maximal exercise testing on an electrically braked bicycle ergometer and 6-meter walk test...
September 19, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
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