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https://www.readbyqxmd.com/read/28214492/youtube-as-a-source-of-patient-information-for-varicose-vein-treatment-options
#1
Trevor M Y Kwok, Animesh A Singla, Kevin Phang, Annie Y S Lau
OBJECTIVE: The purpose of this study was to analyze the quality of content and potential sources of bias in videos available on YouTube pertaining to interventional treatment for varicose veins. METHODS: Searches were performed on YouTube to identify videos pertaining to interventional treatment for varicose veins. Videos that met eligibility criteria were analyzed and rated according to predetermined criteria by two independent assessors, with a third independent assessor to resolve any discrepancy...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28212602/happi-2-a-comprehensive-and-high-quality-map-of-human-annotated-and-predicted-protein-interactions
#2
Jake Y Chen, Ragini Pandey, Thanh M Nguyen
BACKGROUND: Human protein-protein interaction (PPI) data is essential to network and systems biology studies. PPI data can help biochemists hypothesize how proteins form complexes by binding to each other, how extracellular signals propagate through post-translational modification of de-activated signaling molecules, and how chemical reactions are coupled by enzymes involved in a complex biological process. Our capability to develop good public database resources for human PPI data has a direct impact on the quality of future research on genome biology and medicine...
February 17, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28211732/time-reversal-measurement-of-the-p-wave-cross-sections-of-the-7-be-n-%C3%AE-4-he-reaction-for-the-cosmological-li-problem
#3
T Kawabata, Y Fujikawa, T Furuno, T Goto, T Hashimoto, M Ichikawa, M Itoh, N Iwasa, Y Kanada-En'yo, A Koshikawa, S Kubono, E Miyawaki, M Mizuno, K Mizutani, T Morimoto, M Murata, T Nanamura, S Nishimura, S Okamoto, Y Sakaguchi, I Sakata, A Sakaue, R Sawada, Y Shikata, Y Takahashi, D Takechi, T Takeda, C Takimoto, M Tsumura, K Watanabe, S Yoshida
The cross sections of the ^{7}Be(n,α)^{4}He reaction for p-wave neutrons were experimentally determined at E_{c.m.}=0.20-0.81  MeV slightly above the big bang nucleosynthesis (BBN) energy window for the first time on the basis of the detailed balance principle by measuring the time-reverse reaction. The obtained cross sections are much larger than the cross sections for s-wave neutrons inferred from the recent measurement at the n_TOF facility in CERN, but significantly smaller than the theoretical estimation widely used in the BBN calculations...
February 3, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28209101/role-of-heart-rate-variability-in-predicting-post-endoscopic-retrograde-cholangiopancreatography-pancreatitis
#4
Y Tryliskyy, G J Bryce
INTRODUCTION: Early recognition of post-ERCP pancreatitis (PEP) would help deliver an appropriate discharge plan following ERCP. Functioning of the autonomic nervous system can be measured using non-invasive heart rate variability techniques (HRV) and provides quantitative information about the modulation of cardiac vagal and sympathetic activity. Pain evoked sympathetic activation is a well-known phenomenon, as exhibited in those suffering PEP. The aim of this study is to determine if a single post-procedural measurement of HRV identifies those at risk of developing PEP...
September 2016: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/28207546/effects-of-postexercise-ice-water-and-room-temperature-water-immersion-on-the-sensory-organization-of-balance-control-and-lower-limb-proprioception-in-amateur-rugby-players-a-randomized-controlled-trial
#5
Gary C C Chow, Timothy T T Yam, Joanne W Y Chung, Shirley S M Fong
BACKGROUND: This single-blinded, three-armed randomized controlled trial aimed to compare the effects of postexercise ice-water immersion (IWI), room-temperature water immersion (RWI), and no water immersion on the balance performance and knee joint proprioception of amateur rugby players. METHODS: Fifty-three eligible amateur rugby players (mean age ± standard deviation: 21.6 ± 2.9 years) were randomly assigned to the IWI group (5.3 °C), RWI group (25...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28196425/gu%C3%A3-as-alimentarias-para-la-poblaci%C3%A3-n-espa%C3%A3-ola-senc-diciembre-2016-la-nueva-pir%C3%A3-mide-de-la-alimentaci%C3%A3-n-saludable
#6
Grupo Colaborativo de la Senc Diciembre
Objetivo: La Sociedad Española de Nutrición Comunitaria (SENC) planteó en 1994 una guía alimentaria para la población española, renovada en 2001. Se presenta una nueva edición actualizada basada en la mejor evidencia científi ca disponible.Métodos: Desde un enfoque de salud en todas las políticas se convocó un grupo de expertos en nutrición y salud pública vinculados con la SENC para revisar la evidencia sobre dieta-salud, ingesta nutricional y consumo alimentario en la población española, hábitos de preparación y consumo de alimentos, factores determinantes e impacto de la dieta en la sostenibilidad medioambiental...
December 7, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28196356/therapeutic-hypothermia-provides-variable-protection-against-behavioral-deficits-after-neonatal-hypoxia-ischemia-a-potential-role-for-brain-derived-neurotrophic-factor
#7
Johana Diaz, Suleiman Abiola, Nancy Kim, Oliver Avaritt, Debra Flock, Jenny Yu, Frances J Northington, Raul Chavez-Valdez
BACKGROUND: Despite treatment with therapeutic hypothermia (TH), infants who survive hypoxic ischemic (HI) encephalopathy (HIE) have persistent neurological abnormalities at school age. Protection by TH against HI brain injury is variable in both humans and animal models. Our current preclinical model of hypoxia-ischemia (HI) and TH displays this variability of outcomes in neuropathological and neuroimaging end points with some sexual dimorphism. The detailed behavioral phenotype of this model is unknown...
February 15, 2017: Developmental Neuroscience
https://www.readbyqxmd.com/read/28193688/compulsive-social-behavior-emerges-after-selective-ablation-of-striatal-cholinergic-interneurons
#8
Yanina V Martos, Barbara Y Braz, Juan P Beccaria, M Gustavo Murer, Juan E Belforte
The mechanisms underlying social dysfunction in neuropsychiatric conditions like obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) remain uncertain. Dysfunctions in basal ganglia, including reduced number of striatal cholinergic interneurons (SCIN), have been involved in their pathophysiology. To explore the role of SCIN in relation to perseverative behaviors we characterized a new transgenic mouse model in which inducible ablation of SCIN is achieved with high efficiency in a cell-type and region specific manner...
February 13, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28188024/robotic-assisted-gait-training-improves-walking-abilities-in-diplegic-children-with-cerebral-palsy
#9
L Wallard, G Dietrich, Y Kerlirzin, J Bredin
The robotic-assisted gait training therapy (RAGT), based on intensity and repetition of movement, presents beneficial effects on recovery and improvement of postural and locomotor functions of the patient. This study sought to highlight the effect of this RAGT on the dynamic equilibrium control during walking in children with Cerebral Palsy (CP) by analyzing the different postural strategies of the fullbody (upper/lower body) before and after this RAGT in order to generate forward motion while maintaining balance...
February 2, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/28184250/meiotic-outcome-in-two-carriers-of-y-autosome-reciprocal-translocations-selective-elimination-of-certain-segregants
#10
Harita Ghevaria, Roy Naja, Sioban SenGupta, Paul Serhal, Joy Delhanty
BACKGROUND: Reciprocal Y autosome translocations are rare but frequently associated with male infertility. We report on the meiotic outcome in embryos fathered by two males with the karyotypes 46,X,t(Y;4)(q12;p15.32) and 46,X,t(Y;16)(q12;q13). The two couples underwent preimplantation genetic diagnosis (PGD) enabling determination of the segregation types that were compatible with fertilization and preimplantation embryo development. Both PGD and follow up analysis were carried out via fluorescence in situ hybridization (FISH) or array comparative genomic hybridization (aCGH) allowing the meiotic segregation types to be determined in a total of 27 embryos...
2017: Molecular Cytogenetics
https://www.readbyqxmd.com/read/28179492/indicator-amino-acid-derived-estimate-of-dietary-protein-requirement-for-male-bodybuilders-on-a-nontraining-day-is-several-fold-greater-than-the-current-recommended-dietary-allowance
#11
Arash Bandegan, Glenda Courtney-Martin, Mahroukh Rafii, Paul B Pencharz, Peter Wr Lemon
Background: Despite a number of studies indicating increased dietary protein needs in bodybuilders with the use of the nitrogen balance technique, the Institute of Medicine (2005) has concluded, based in part on methodologic concerns, that "no additional dietary protein is suggested for healthy adults undertaking resistance or endurance exercise."Objective: The aim of the study was to assess the dietary protein requirement of healthy young male bodybuilders ( with ≥3 y training experience) on a nontraining day by measuring the oxidation of ingested l-[1-(13)C]phenylalanine to (13)CO2 in response to graded intakes of protein [indicator amino acid oxidation (IAAO) technique]...
February 8, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28179257/interplay-between-renal-endothelin-and-purinergic-signaling-systems
#12
Eman Y Gohar, Malgorzata Kasztan, David M Pollock
Alterations in extracellular fluid volume regulation and sodium balance may result in the development and maintenance of salt-dependent hypertension, a major risk factor for cardiovascular disease. Numerous pathways contribute to the regulation of sodium excretion and blood pressure, including endothelin and purinergic signaling. Increasing evidence suggests a link between purinergic receptor activation and endothelin production within the renal collecting duct as a means of promoting natriuresis. A better understanding of the relationship between these two systems, especially in regard to sodium homeostasis, will fill a significant knowledge gap and may provide novel antihypertensive treatment options...
February 8, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28179223/substituting-whole-grains-for-refined-grains-in-a-6-wk-randomized-trial-favorably-affects-energy-balance-metrics-in-healthy-men-and-postmenopausal-women
#13
J Philip Karl, Mohsen Meydani, Junaidah B Barnett, Sally M Vanegas, Barry Goldin, Anne Kane, Helen Rasmussen, Edward Saltzman, Pajau Vangay, Dan Knights, C-Y Oliver Chen, Sai Krupa Das, Satya S Jonnalagadda, Simin N Meydani, Susan B Roberts
Background: The effect of whole grains on the regulation of energy balance remains controversial.Objective: We aimed to determine the effects of substituting whole grains for refined grains, independent of body weight changes, on energy-metabolism metrics and glycemic control.Design: The study was a randomized, controlled, parallel-arm controlled-feeding trial that was conducted in 81 men and postmenopausal women [49 men and 32 women; age range: 40-65 y; body mass index (in kg/m(2)): <35.0]. After a 2-wk run-in period, participants were randomly assigned to consume 1 of 2 weight-maintenance diets for 6 wk...
February 8, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28177751/evidence-of-nonlocal-muscle-fatigue-in-male-youth
#14
Aymen Ben Othman, Anis Chaouachi, Mehdi M Chaouachi, Raouf Hammami, Sofien Kasmi, David G Behm
Evidence for nonlocal muscle fatigue (NLMF) has been inconsistent in adults, with no studies investigating youth. The objective was to examine NLMF in youth. Forty-two young males (age, 10-13 years) were tested for maximal voluntary isometric contraction (MVIC) force of the ipsilateral and contralateral knee extensors at 90° and 120° knee flexion, elbow flexors at 90°, handgrip, knee extensor isokinetic torque (300(o)·s(-1) analyzed at 90(o) and 120(o) knee flexion), as well as a unilateral countermovement jump (CMJ) and Y Balance test (YBT)...
November 2, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28176514/comparison-of-hepatectomy-with-or-without-hepatic-inflow-occlusion-in-patients-with-hepatocellular-carcinoma-a-single-center-experience
#15
Jing H Jiang, Kai X Wang, Ji Y Zhu, Pei P Yang, Zhe Guo, Song L Ma, Yang Lv, Bang D Xiang, Jian H Zhong, Le Q Li
BACKGROUND: The negative effects of hepatic inflow occlusion (HIO) on postoperative liver function of patients with hepatocellular carcinoma (HCC) after liver resection have been reported. Nevertheless, whether HIO could influence the long-term outcomes remains unclear. METHODS: A total of 396 patients were included in this study and divided into without occlusion (WO) group (n=112) and HIO group (n=284). Aiming to minimize influence of selection bias and confounding variables, we used propensity score matching (PSM) of a 0...
February 7, 2017: Minerva Medica
https://www.readbyqxmd.com/read/28174470/reliability-and-validity-of-the-sequential-weight-shifting-test-a-new-functional-approach-to-the-assessment-of-the-sitting-balance-of-older-adults
#16
Ken Y T Lee, Christina W Y Hui-Chan, William W N Tsang
[Purpose] The evaluation of sitting balance is important for the prevention of falls in older adults, especially those who have a disability involving the lower extremities. However, no studies have been designed to assess a patient's dynamic sitting balance using a sequential protocol. The objective of this study was to investigate the psychometric properties of the sequential weight-shifting (SWS) test. [Subjects and Methods] Twenty-three older adults who were physically dependent with regard to ambulation were recruited by convenience sampling...
December 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28169941/novel-index-to-quantify-the-risk-of-surgery-in-the-setting-of-adult-spinal-deformity-a-study-on-10-912-patients-from-the-nationwide-inpatient-sample
#17
Bassel G Diebo, Cyrus M Jalai, Vincent Challier, Bryan J Marascalchi, Samantha R Horn, Gregory W Poorman, Olivia J Bono, Denis Cherkalin, Nancy Worley, Jason Oh, Qais Naziri, Allison Spitzer, Kris Radcliff, Ashish Patel, Virginie Lafage, Carl B Paulino, Peter G Passias
STUDY DESIGN: Retrospective review of the Nationwide Inpatient Sample from 2001 to 2010, a prospectively collected national database. OBJECTIVE: Structure an index to quantify adult spinal deformity (ASD) surgical risk based on risk factors for medical complications, surgical complications, revisions (R), mortality (M) rates, and length of hospital stay. SUMMARY OF BACKGROUND DATA: Evidence supporting ASD surgery cost-effectiveness and anticipating surgical risk is critical to evaluate the risk/benefit balance of such treatment for patients...
February 6, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28166980/effect-of-energy-balance-profiles-on-metabolic-and-reproductive-response-in-holstein-and-swedish-red-cows
#18
T Ntallaris, P Humblot, R Båge, Y Sjunnesson, J Dupont, B Berglund
This study examined the effect of two feeding levels during the antepartum and postpartum period on reproductive performance and blood metabolites (glucose, non-esterified fatty acids (NEFA), insulin) in primiparous Holstein and Swedish Red (SRB) cows, in order to identify possible differences in the way these breeds respond to negative energy balance after calving. A total of 44 cows (22 Holstein, 22 SRB) kept in a loose housing system were included in the study. The control group (HE, n = 23) was fed a diet for high-producing cows (target 35 kg/d energycorrected milk, ECM)...
March 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28166414/who-wears-the-pants-the-implications-of-gender-and-power-for-youth-heterosexual-relationships
#19
Laina Y Bay-Cheng, Eugene Maguin, Anne E Bruns
Relationships in which power is equally distributed are consistently associated with greater quality (e.g., deeper intimacy, less turmoil, more pleasure), but it can be difficult to strike such a balance. Furthermore, dominant gender scripts and norms are complexly intertwined with power in heterosexual relationships. We studied the joint implications of power and gender for relationship quality using 114 U.S. emerging adults' quantitative and qualitative assessments of 395 heterosexual relationships. Linear mixed method analyses indicated that participants found relationships in which they shared power or were dominant to be more intimate and stable than those in which they felt subordinate, but we found no link between power and pleasure...
February 6, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28166201/downregulation-of-pck2-remodels-tricarboxylic-acid-cycle-in-tumor-repopulating-cells-of-melanoma
#20
S Luo, Y Li, R Ma, J Liu, P Xu, H Zhang, K Tang, J Ma, N Liu, Y Zhang, Y Sun, T Ji, X Liang, X Yin, Y Liu, W Tong, Y Niu, N Wang, X Wang, B Huang
For cancer cells to proliferate, a balance must be built between biomass-forming, glucose-metabolized intermediates and ATP production. How intrinsic glucose carbon flow regulates this balance remains unclear. Here we show that mitochondrial phosphoenolpyruvate carboxykinase (PCK2), the hub molecule linking tricarboxylic acid (TCA) cycle, glycolysis and gluconeogenesis by conversion of mitochondrial oxaloacetate (OAA) to phosphoenolpyruvate, regulates glucose carbon flow direction in stem-like cells that repopulate tumors (tumor-repopulating cells (TRCs))...
February 6, 2017: Oncogene
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