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https://www.readbyqxmd.com/read/28315826/early-invasive-strategy-and-in-hospital-survival-among-diabetics-with-non-st-elevation-acute-coronary-syndromes-a-contemporary-national-insight
#1
Ahmed N Mahmoud, Islam Y Elgendy, Hend Mansoor, Xuerong Wen, Mohammad K Mojadidi, Anthony A Bavry, R David Anderson
BACKGROUND: There are limited data on the merits of an early invasive strategy in diabetics with non-ST-elevation acute coronary syndrome, with unclear influence of this strategy on survival. The aim of this study was to evaluate the in-hospital survival of diabetics with non-ST-elevation acute coronary syndrome treated with an early invasive strategy compared with an initial conservative strategy. METHODS AND RESULTS: The National Inpatient Sample database, years 2012-2013, was queried for diabetics with a primary diagnosis of non-ST-elevation acute coronary syndrome defined as either non-ST-elevation myocardial infarction or unstable angina (unstable angina)...
March 18, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28315285/effects-of-plyometric-training-on-physical-fitness-in-prepuberal-soccer-athletes
#2
Yassine Negra, Helmi Chaabene, Senda Sammoud, Raja Bouguezzi, Mohamed Aymen Abbes, Younés Hachana, Urs Granacher
This study aimed at examining the effects of plyometric training on stable (SPT) vs. unstable (UPT) surfaces on physical fitness in prepuberal soccer players. Male athletes were randomly assigned to SPT (n=18; age=12.7±0.2 years) or UPT (n=16; age=12.2±0.5 years). Both groups conducted 3 regular soccer training sessions per week combined with either 2 SPT or UPT sessions. Assessment of jumping ability (countermovement jump [CMJ], and standing long jump [SLJ]), speed (10-m, 20-m, 30-m sprint), agility (Illinois agility test [IAT]), and balance (stable [SSBT], unstable [USBT] stork balance test; stable [SYBT], unstable [UYBT] Y balance test) was conducted pre-and post-training...
March 17, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28314964/increased-intake-of-energy-dense-diet-and-negative-energy-balance-in-a-mouse-model-of-chronic-psychosocial-defeat
#3
Roberto Coccurello, Adele Romano, Giacomo Giacovazzo, Bianca Tempesta, Marco Fiore, Anna Maria Giudetti, Ilaria Marrocco, Fabio Altieri, Anna Moles, Silvana Gaetani
PURPOSE: Chronic exposure to stress may represent a risk factor for developing metabolic and eating disorders, mostly driven by the overconsumption of easily accessible energy-dense palatable food, although the mechanisms involved remain still unclear. In this study, we used an ethologically oriented murine model of chronic stress caused by chronic psychosocial defeat (CPD) to investigate the effects of unrestricted access to a palatable high fat diet (HFD) on food intake, body weight, energy homeostasis, and expression of different brain neuropeptides...
March 17, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28303719/pentanuclear-lanthanide-mono-organophosphates-synthesis-structure-and-magnetism
#4
Sandeep K Gupta, Stuart K Langley, Kamna Sharma, Keith S Murray, Ramaswamy Murugavel
Research on rare-earth phosphates has recently received substantial interest because of their unique physical and chemical properties. In recent years, because of their low solubility, research interest has been built on developing methodologies to prepare nanostructures and grow single crystals of inorganic rare-earth phosphates. The chemistry of rare-earth organophosphates, however, is still at a latent stage. Contrary to the traditional hydrothermal route, we report rare examples of discrete pentanuclear lanthanide(III) organophosphate clusters assembled from a sterically encumbered monoester of phosphoric acid under mild reaction conditions...
March 17, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28302708/thermoregulatory-responses-to-exercise-at-a-fixed-rate-of-heat-production-are-not-altered-by-acute-hypoxia
#5
Geoff B Coombs, Matthew N Cramer, Nicholas Ravanelli, Pascal Imbeault, Ollie Jay
This study sought to assess the within-subject influence of acute hypoxia on exercise-induced changes in core temperature and sweating. Eight participants [1.75 (0.06) m, 70.2 (6.8) kg, 25 (4) y, 54 (8) mL(.)kg(-1)(.)min(-1)] completed 45 min of cycling, once in normoxia (NORM; FiO2=0.21) and twice in hypoxia (HYP1/HYP2; FiO2=0.13) at 34.4(0.2)°C, 46(3)% RH. These trials were designed to elicit a) two distinctly different %VO2peak [NORM:45(8)% and HYP1:62(7)%] at the same heat production (Hprod) [NORM:6.7(0...
March 16, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28300870/effectiveness-and-safety-of-apixaban-versus-warfarin-in-non-valvular-atrial-fibrillation-patients-in-real-world-clinical-practice-a-propensity-matched-analysis-of-76-940-patients
#6
Xiaoyan Li, Steve Deitelzweig, Allison Keshishian, Melissa Hamilton, Ruslan Horblyuk, Kiran Gupta, Xuemei Luo, Jack Mardekian, Keith Friend, Anagha Nadkarni, Xianying Pan, Gregory Y H Lip
The ARISTOTLE trial showed a risk reduction of stroke/systemic embolism (SE) and major bleeding in non-valvular atrial fibrillation (NVAF) patients treated with apixaban compared to warfarin. This retrospective study used four large US claims databases (MarketScan, PharMetrics, Optum, and Humana) of NVAF patients newly initiating apixaban or warfarin from January 1, 2013 to September 30, 2015. After 1:1 warfarin-apixaban propensity score matching (PSM) within each database, the resulting patient records were pooled...
March 16, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28294377/cumene-hydroperoxide-induced-changes-in-oxidation-reduction-potential-in-fresh-and-frozen-seminal-ejaculates
#7
A Agarwal, R Sharma, R Henkel, S Roychoudhury, S C Sikka, S du Plessis, Y B Sarda, C Speyer, M Nouh, C Douglas, Z Kayali, E S Ahmed, E Sabanegh
Oxidation-reduction potential (ORP) is a newer integrated measure of the balance between total oxidants (reactive oxygen species-ROS) and reductants (antioxidants) that reflects oxidative stress in a biological system. This study measures ORP and evaluates the effect of exogenous induction of oxidative stress by cumene hydroperoxide (CH) on ORP in fresh and frozen semen using the MiOXSYS Analyzer. Semen samples from healthy donors (n = 20) were collected and evaluated for sperm parameters. All samples were then flash-frozen at -80°C...
March 15, 2017: Andrologia
https://www.readbyqxmd.com/read/28294152/melanocortin-3-receptors-expressed-in-nkx2-1-ve-neurons-are-sufficient-for-controlling-appetitive-responses-to-hypocaloric-conditioning
#8
Clémence Girardet, Maria M Mavrikaki, Joseph R Stevens, Courtney A Miller, Daniel L Marks, Andrew A Butler
Melanocortin-3 receptors (MC3R) have a contextual role in appetite control that is amplified with hypocaloric conditioning. C57BL/6J (B6) mice subjected to hypocaloric feeding schedules (HFS) exhibit compulsive behavioral responses involving food anticipatory activity (FAA) and caloric loading following food access. These homeostatic responses to calorie-poor environs are attenuated in B6 mice in which Mc3r transcription is suppressed by a lox-stop-lox sequence in the 5'UTR (Mc3r(TB/TB)). Here, we report that optimization of caloric loading in B6 mice subject to HFS, characterized by increased meal size and duration, is not observed in Mc3r(TB/TB) mice...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28293482/psychometric-properties-of-brief-balance-evaluation-systems-test-brief-bestest-in-evaluating-balance-performance-in-individuals-with-chronic-stroke
#9
Meizhen Huang, Marco Y C Pang
OBJECTIVE: To examine the psychometric properties of the Brief-Balance Evaluation Systems Test (Brief-BESTest) in individuals with chronic stroke. MATERIALS AND METHODS: This was an observational study with repeated measurements involving 50 participants with chronic stroke [mean (SD) age: 59.2 (7.3) years]. Each participant with stroke was evaluated with the Brief-BESTest, Berg balance scale (BBS), Postural Assessment Scale for Stroke Patients (PASS), Fugl-Meyer Motor Assessment (FMA), Chedoke-McMaster Stroke Assessment (CMSA), Montreal Cognitive Assessment (MoCA), and Geriatric Depression Scale (GDS)...
March 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28291591/the-inma-infancia-y-medio-ambiente-environment-and-childhood-project-more-than-10-years-contributing-to-environmental-and-neuropsychological-research
#10
REVIEW
Mireia Gascon, Mònica Guxens, Martine Vrijheid, Maties Torrent, Jesús Ibarluzea, Eduardo Fano, Sabrina Llop, Ferran Ballester, Mariana F Fernández, Adonina Tardón, Ana Fernández-Somoano, Jordi Sunyer
BACKGROUND: In 2003 the INMA-INfancia y Medio Ambiente (Environment and Childhood) project, a Spanish national network of birth cohorts including more than 3500 participants, was set up with the aim to assess the health impacts of pre- and postnatal environmental exposures on children. The project has published more than 60 papers on maternal and environmental factors related to neuropsychological development in children, one of the main research interests within the project. With the present review, we evaluate the evidence provided by the INMA project on this topic and discuss how the data can contribute to cover the challenges that children's environmental health research will face in the coming years...
February 28, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28288896/age-and-menopause-related-differences-in-subcutaneous-adipose-tissue-estrogen-receptor-mrna-expression
#11
Young-Min Park, Christopher Erickson, Dan Bessesen, Rachael E Van Pelt, Kimberly Cox-York
OBJECTIVES: Changes in estrogen receptor (ER) expression likely underlie differential metabolic effects of estrogen in pre- and postmenopausal women. The aim of the current study was to determine whether ER gene expression in abdominal and femoral subcutaneous adipose tissue (SAT) was associated with age, menopause, or regional adiposity. METHODS: We studied pre- and post-menopausal (n=23 and 22, respectively; age 35-65 y) normal weight (mean±SD; BMI 23.7±2.5 kg/m(2)) women with similar total fat mass...
March 10, 2017: Steroids
https://www.readbyqxmd.com/read/28286959/dietary-guidelines-for-the-spanish-population-senc-december-2016-the-new-graphic-icon-of-healthy-nutrition
#12
Javier Aranceta Bartrina, Victoria Arija Val, Edurne Maíz Aldalur, Emilio Martínez de la Victoria Muñoz, Rosa María Ortega Anta, Carmen Pérez-Rodrigo, Joan Quiles Izquierdo, Amelia Rodríguez Martín, Blanca Román Viñas, Gemma Salvador Castell, Josep Antoni Tur Marí, Gregorio Varela Moreiras, Lluis Serra Majem
Objective: The Spanish Society of Community Nutrition (SENC) designed in 1994 a food guide for the Spanish population, updated in 2001. This report presents a new updated edition based on the best scientifi c evidence available. Methods: From a health in all policies approach, a group of experts in nutrition and public health associated with SENC was convened to review the evidence on diet-health, nutrition intake and food consumption in the Spanish population, as well as food preparation and consumption habits, determinants and impact of diet on environmental sustainability...
December 7, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28275129/declining-consumption-of-added-sugars-and-sugar-sweetened-beverages-in-australia-a-challenge-for-obesity-prevention
#13
Jennie C Brand-Miller, Alan W Barclay
Background: Reduced intakes of added sugars and sugar-sweetened beverages (SSBs) have been the main focus of efforts to stall obesity. Although obesity has risen steeply in Australia, some evidence suggests that added-sugars and SSB intakes have declined over the same time frame.Objective: We investigated recent trends in the availability of sugars and sweeteners and changes in intakes of total sugars, added sugars, and SSBs in Australia by using multiple, independent data sources.Design: The study was designed to compare relevant data published by the Food and Agriculture Organization of the United Nations [FAO Statistics Division Database (FAOSTAT)], the Australian government, academia, and the food industry...
March 8, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28274795/anthropological-analysis-of-tunisian-populations-as-inferred-from-hla-class-i-and-class-ii-genetic-diversity-a-meta-analysis
#14
Abdelhafidh Hajjej, Wassim Y Almawi, Lasmar Hattab, Slama Hmida
Despite their importance, anthropological meta-analyses which allow for comprehensive evaluation of the relationships of a given population were rare. This meta-analysis evaluates the origin of Tunisians using polymorphic profile of HLA class I (A, B), and class II (DRB1, DQB1) genes, in historical, social and cultural context, and is the only analysis in the Middle East-North Africa (MENA) region. A total of 20 eligible populations were selected from several databases, and included representing 2553 Tunisian individuals, who were compared with Mediterranean and sub-Saharan populations...
March 6, 2017: Immunology Letters
https://www.readbyqxmd.com/read/28271424/a-randomized-controlled-multisite-study-of-behavioral-interventions-for-veterans-with-mental-illness-and-antipsychotic-medication-associated-obesity
#15
Zachary D Erickson, Crystal L Kwan, Hollie A Gelberg, Irina Y Arnold, Valery Chamberlin, Jennifer A Rosen, Chandresh Shah, Charles T Nguyen, Gerhard Hellemann, Dixie R Aragaki, Charles F Kunkel, Melissa M Lewis, Neena Sachinvala, Patrick A Sonza, Joseph M Pierre, Donna Ames
BACKGROUND: Weight gain and other metabolic sequelae of antipsychotic medications can lead to medication non-adherence, reduced quality of life, increased costs, and premature mortality. Of the approaches to address this, behavioral interventions are less invasive, cost less, and can result in sustained long-term benefits. OBJECTIVE: We investigated behavioral weight management interventions for veterans with mental illness across four medical centers within the Veterans Affairs (VA) Healthcare System...
March 7, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28271363/yfiler-%C3%A2-plus-population-samples-and-dilution-series-stutters-analytic-thresholds-and-drop-out-probabilities
#16
Mikkel Meyer Andersen, Helle Smidt Mogensen, Poul Svante Eriksen, Niels Morling
The Yfiler (Ⓡ) Plus Amplification Kit amplifies 27 Y chromosomal small tandem repeat (STR) markers. The kit has five-fluorescent dye chemistry and the improved PCR buffer system of modern STR kits. We validated the kit for accredited investigations of crime scene samples by a thorough study of kit dynamics and performance. We determined dye-dependent analytical thresholds by receiver operating characteristics (ROC) and made a customised artefact filter that includes theoretical known artefacts by use of previously analysed population samples...
March 7, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28267788/dementia-incidence-trend-over-1992-2014-in-the-netherlands-analysis-of-primary-care-data
#17
Emma F van Bussel, Edo Richard, Derk L Arts, Astrid C J Nooyens, Preciosa M Coloma, Margot W M de Waal, Marjan van den Akker, Marion C J Biermans, Markus M J Nielen, Kees van Boven, Hugo Smeets, Fiona E Matthews, Carol Brayne, Wim B Busschers, Willem A van Gool, Eric P Moll van Charante
BACKGROUND: Recent reports have suggested declining age-specific incidence rates of dementia in high-income countries over time. Improved education and cardiovascular health in early age have been suggested to be bringing about this effect. The aim of this study was to estimate the age-specific dementia incidence trend in primary care records from a large population in the Netherlands. METHODS AND FINDINGS: A dynamic cohort representative of the Dutch population was composed using primary care records from general practice registration networks (GPRNs) across the country...
March 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28261500/efficacy-of-wii-fit-on-static-and-dynamic-balance-in-community-dwelling-older-veterans-a-randomized-controlled-pilot-trial
#18
Kalpana P Padala, Prasad R Padala, Shelly Y Lensing, Richard A Dennis, Melinda M Bopp, Christopher M Parkes, Mark K Garrison, Patricia M Dubbert, Paula K Roberson, Dennis H Sullivan
Background/Objectives. Balance problems are well-established modifiable risk factors for falls, which are common in older adults. The objective of this study was to establish the efficacy of a Wii-Fit interactive video-game-led physical exercise program to improve balance in older Veterans. Methods. A prospective randomized controlled parallel-group trial was conducted at Veterans Affairs Medical Center. Thirty community dwelling Veterans aged 68 (±6.7) years were randomized to either the exercise or control groups...
2017: Journal of Aging Research
https://www.readbyqxmd.com/read/28259403/evaluation-of-the-national-research-council-2001-dairy-model-and-derivation-of-new-prediction-equations-1-digestibility-of-fiber-fat-protein-and-nonfiber-carbohydrate
#19
R R White, Y Roman-Garcia, J L Firkins, M J VandeHaar, L E Armentano, W P Weiss, T McGill, R Garnett, M D Hanigan
Evaluation of ration balancing systems such as the National Research Council (NRC) Nutrient Requirements series is important for improving predictions of animal nutrient requirements and advancing feeding strategies. This work used a literature data set (n = 550) to evaluate predictions of total-tract digested neutral detergent fiber (NDF), fatty acid (FA), crude protein (CP), and nonfiber carbohydrate (NFC) estimated by the NRC (2001) dairy model. Mean biases suggested that the NRC (2001) lactating cow model overestimated true FA and CP digestibility by 26 and 7%, respectively, and under-predicted NDF digestibility by 16%...
March 2, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28257334/an-unbalanced-inflammatory-cytokine-response-is-not-associated-with-mortality-following-sepsis-a-prospective-cohort-study
#20
Jos F Frencken, Lonneke A van Vught, Linda M Peelen, David S Y Ong, Peter M C Klein Klouwenberg, Janneke Horn, Marc J M Bonten, Tom van der Poll, Olaf L Cremer
OBJECTIVE: The prevailing theory of host response during sepsis states that an excessive production of pro-inflammatory mediators causes early deaths, whereas a predominantly anti-inflammatory response may lead to immunosuppression, secondary infection, and late deaths. We assessed inflammatory (im)balance by measuring pro-inflammatory interleukin-6 and anti-inflammatory interleukin-10 during three distinct time periods after sepsis, and assessed its association with mortality. DESIGN: Prospective observational cohort...
March 2, 2017: Critical Care Medicine
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