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https://www.readbyqxmd.com/read/28343376/ruthenium-106-brachytherapy-with-or-without-additional-local-therapy-showed-favorable-outcome-for-variable-sized-choroidal-melanomas-in-korean-patients
#1
Yeona Cho, Jee Suk Chang, Jin Sook Yoon, Sung Chul Lee, Yong Bae Kim, Joo Ho Kim, Ki Chang Keum
Purpose: To report clinical outcomes of ruthenium-106 (Ru-106) brachytherapy with or without additional local therapy for choroidal melanomas in Korean patients. Materials and Methods: A total of 88 patients diagnosed with choroidal melanomas were treated with Ru-106 brachytherapy between 2006 and 2012. Patients were divided into two groups according to their tumor height: a large group (≥6 mm, n=50) and a small group (<6 mm, n=38). Most patients in the large group received combined therapy with local excision and/or transpupillary thermotherapy...
March 24, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28343369/heavier-birth-weight-associated-with-taller-height-but-not-age-at-menarche-in-us-women-born-1991-1998
#2
Megan Workman, Karina Kelly
OBJECTIVES: Heavier birth weight predicts taller adult height, but it remains unknown the extent to which this additional height increment results from a faster average growth rate versus an extension of the growth period. Aiming to distinguish these effects, this study examined associations between birth weight (BW), age at menarche (an established proxy for growth duration), and near-adult height in a cohort of US young women born in the 1990s. METHODS: Multiple regression evaluated age-adjusted height as an outcome of BW, age at menarche, indicators of family socioeconomic status, and other potential confounders in a sample of US teens who participated in the National Health and Nutrition Examination Survey between 2007 and 2012 (N = 342)...
March 26, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28343360/tsunami-run-up-and-inundation-along-the-coast-of-sabah-and-sarawak-malaysia-due-to-a-potential-brunei-submarine-mass-failure
#3
Wai Kiat Tan, Su Yean Teh, Hock Lye Koh
Submarine landslides, also known as submarine mass failures (SMFs), are major natural marine disasters that could critically damage coastal facilities such as nuclear power plants and oil and gas platforms. It is therefore essential to investigate submarine landslides for potential tsunami hazard assessment. Three-dimensional seismic data from offshore Brunei have revealed a giant seabed mass deposited by a previous SMF. The submarine mass extends over 120 km from the continental slope of the Baram Canyon at 200 m water depth to the deep basin floor of the Northwest Borneo Trough...
March 25, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28343307/modular-organization-of-muscle-activity-patterns-in-the-leading-and-trailing-limbs-during-obstacle-clearance-in-healthy-adults
#4
Michael J MacLellan
Human locomotor patterns require precise adjustments to successfully navigate complex environments. Studies suggest that the central nervous system may control such adjustments through supraspinal signals modifying a basic locomotor pattern at the spinal level. To explore this proposed control mechanism in the leading and trailing limbs during obstructed walking, healthy young adults stepped over obstacles measuring 0.1 and 0.2 m in height. Unobstructed walking with no obstacle present was also performed as a baseline...
March 25, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28343254/dynamic-measurements-of-cervical-neural-foramina-during-neck-movements-in-asymptomatic-young-volunteers
#5
Victor Chang, Azam Basheer, Timothy Baumer, Daniel Oravec, Colin P McDonald, Michael J Bey, Stephen Bartol, Yener N Yeni
PURPOSE: Neural foraminal dimensions are considered important in nerve root compression and development of cervical radiculopathy, but baseline data regarding their range during normal motion are not available. An in vivo study of cervical foraminal motion was conducted to characterize normal 3D dynamic foraminal dimensions during physiological neck motion and compare between different tasks and intervertebral segments. METHODS: Biplane X-ray imaging and computed tomography-based markerless tracking were used to measure foraminal height (FH) and width (FW) from five asymptomatic subjects during neck axial rotation and extension...
March 25, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28343249/intraobserver-and-interobserver-variability-in-ct-angiography-and-mr-angiography-measurements-of-the-size-of-cerebral-aneurysms
#6
Hye Jeong Kim, Dae Young Yoon, Eun Soo Kim, Hyung Jin Lee, Hong Jun Jeon, Jong Young Lee, Byung-Moon Cho
PURPOSE: Accurate and reliable measurement of aneurysm size is important for treatment planning. The purpose of this study was to determine intraobserver and interobserver variability of CTA and MRA for measurement of the size of cerebral aneurysms. METHODS: Thirty patients with 33 unruptured cerebral aneurysms (saccular, >3 mm in their maximal dimension, with no daughter sacs or lobulations) who underwent 256-row multislice CTA, 3-D TOF MRA at 3.0T, and 3D rotational angiography (3DRA) were retrospectively analyzed...
March 25, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28343179/nulliparous-teenagers-and-preterm-birth-in-california
#7
Jonathan A Mayo, Bat Zion Shachar, David K Stevenson, Gary M Shaw
BACKGROUND: Young maternal age is one of the numerous risk factors for delivery before 37 weeks of gestation, yet the mechanisms are unclear. The purpose of the current study was to investigate the association between teenagers and the risk of preterm birth (PTB) in a large and recent cohort study. METHODS: We conducted a population-based retrospective cohort study using 2007-2011 California birth certificate records linked with hospital discharge indices and United States census data for nulliparous 13-20 year olds who gave birth to singletons...
March 27, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28343116/health-and-weight-gender-specific-linkages-under-heterogeneity-interdependence-and-resilience-factors
#8
Olaf Hübler
Many studies have shown that obesity is a serious health problem for our society. Empirical analyses often neglect a number of methodological issues and relevant influences on health. This paper investigates empirically whether neglecting these items leads to systematically different estimates. Based on data from the German Socio-Economic Panel, this study derives the following results. (1) Many combinations of weight and height lead to the same health status. (2) The relationship between health and body mass index is nonlinear...
March 11, 2017: Economics and Human Biology
https://www.readbyqxmd.com/read/28343026/comparison-of-unilateral-versus-bilateral-pedicle-screw-fixation-at-the-level-of-fracture-using-posterior-short-segment-pedicle-instrumentation-in-the-treatment-of-severe-thoracolumbar-burst-fractures
#9
Chao Sun, Xinhui Liu, Jiwei Tian, Guoping Guan, Hailong Zhang
BACKGROUND: Thoracolumbar burst fractures (TBFs) are often followed by bilateral pedicle screw fixation(BPSF) at the level of fracture using posterior short-segment pedicle instrumentation (SSPI). There has been increasing support for unilateral pedicle screw fixation (UPSF) in an attempt to reduce complications and costs. The aim of this study was to compare the clinical and radiologic results of UPSF versus BPSF at the level of fracture using SSPI in the treatment of severe TBFs. METHODS: The records of 42 consecutive patients with severe TBFs who underwent SSPI were divided into 2 groups according to the number of screws in the fracture level, including 20 patients (five screws) in UPSF group and 22 patients(six screws) in BPSF...
March 22, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28342814/tear-cytokine-profile-of-glaucoma-patients-treated-with-preservative-free-or-preserved-latanoprost
#10
Jose M Martinez-de-la-Casa, Francisco Perez-Bartolome, Elena Urcelay, Jose L Santiago, Javier Moreno-Montañes, Pedro Arriola-Villalobos, Jose M Benitez-Del-Castillo, Julian Garcia-Feijoo
PURPOSE: To determine variations in cytokine levels of glaucoma patients treated either with preservative-free latanoprost or preserved latanoprost, relative to healthy individuals. METHODS: Tear samples were collected from 39 healthy subjects, 20 glaucoma patients treated with preserved latanoprost, and 20 patients treated with preservative-free latanoprost. A set of 27 inflammatory cytokines was analyzed in each group, including interleukin (IL)-1β, IL-1ra, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL9, IL-10, IL-12 (p70), IL-13, IL-15, IL-17, eotaxin, fibroblast growth factor (FGF) basic, granulocyte colony stimulating factor (G-CSF), granulocyte monocyte colony stimulating factor (GM-CSF), interferon (IFN)-γ, interferon gamma-induced protein (IP)-10, monocyte chemo attractant protein (MCP)-1MCAF, macrophage inflammatory protein (MIP)-1α, MIP-1β, platelet-derived growth factor (PDGF)-BB, regulated on activation, normal T cell expressed and secreted (RANTES), tumor necrosis factor (TNF)-α and vascular endothelial growth factor (VEGF)...
March 22, 2017: Ocular Surface
https://www.readbyqxmd.com/read/28342610/intentionally-induced-intestinal-barrier-dysfunction-causes-inflammation-affects-metabolism-and-reduces-productivity-in-lactating-holstein-cows
#11
S K Kvidera, M J Dickson, M Abuajamieh, D B Snider, M V Sanz Fernandez, J S Johnson, A F Keating, P J Gorden, H B Green, K M Schoenberg, L H Baumgard
Study objectives were to evaluate the effects of intentionally reduced intestinal barrier function on productivity, metabolism, and inflammatory indices in otherwise healthy dairy cows. Fourteen lactating Holstein cows (parity 2.6 ± 0.3; 117 ± 18 d in milk) were enrolled in 2 experimental periods. Period 1 (5 d) served as the baseline for period 2 (7 d), during which cows received 1 of 2 i.v. treatments twice per day: sterile saline or a gamma-secretase inhibitor (GSI; 1.5 mg/kg of body weight). Gamma-secretase inhibitors reduce intestinal barrier function by inhibiting crypt cell differentiation into absorptive enterocytes...
March 22, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28342508/gender-smoking-body-size-and-aneurysm-geometry-influence-the-biomechanical-rupture-risk-of-abdominal-aortic-aneurysms-as-estimated-by-finite-element-analysis
#12
Moritz Lindquist Liljeqvist, Rebecka Hultgren, Antti Siika, T Christian Gasser, Joy Roy
OBJECTIVE: Finite element analysis (FEA) has been suggested to be superior to maximal diameter measurements in predicting rupture of abdominal aortic aneurysms (AAAs). Our objective was to investigate to what extent previously described rupture risk factors were associated with FEA-estimated rupture risk. METHODS: One hundred forty-six patients with an asymptomatic AAA of a 40- to 60-mm diameter were retrospectively identified and consecutively included. The patients' computed tomography angiograms were analyzed by FEA without (neutral) and with (specific) input of patient-specific mean arterial pressure (MAP), gender, family history, and age...
April 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28340457/dermal-exposure-of-applicators-to-chlorpyrifos-on-rice-farms-in-ghana
#13
Albert Atabila, Dung Tri Phung, Jonathan N Hogarh, Paul Osei-Fosu, Ross Sadler, Des Connell, Cordia Chu
Studies evaluating dermal exposure to pesticides among applicators in tropical countries have largely been conducted using the patch dosimetry and hand wiping/washing techniques. This study used the more accurate whole-body dosimetry technique to evaluate dermal exposure to chlorpyrifos among applicators on rice farms in Ghana. The exposure levels were plotted as Cumulative Probability Distribution (CPD). Total Dermal Exposure (TDE) of chlorpyrifos among the median exposed and the 5% highly exposed groups during a spray event were 24 mg and 48 mg, respectively...
March 16, 2017: Chemosphere
https://www.readbyqxmd.com/read/28340405/population-pharmacokinetic-modeling-of-furosemide-in-patients-with-hypertension-and-fluid-overload-conditions
#14
Devender Kodati, Narsimhareddy Yellu
BACKGROUND: Furosemide is a loop diuretic drug frequently indicated in hypertension and fluid overload conditions such as congestive heart failure and hepatic cirrhosis. OBJECTIVE: The purpose of the study was to establish a population pharmacokinetic model for furosemide in Indian hypertensive and fluid overload patients, and to evaluate effects of covariates on the volume of distribution (V/F) and oral clearance (CL/F) of furosemide. METHODS: A total of 188 furosemide plasma sample concentrations from 63 patients with hypertension or fluid overload conditions were collected in this study...
January 15, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28340391/optimization-of-the-marinelli-beaker-dimensions-using-genetic-algorithm
#15
Seyed Mehrdad Zamzamian, Seyed Abolfazl Hosseini, Mohammad Samadfam
A computational code, based on the genetic algorithm and MCNPX version 2.6 code was developed and used to investigate the effects of some important parameters of HPGe detector (such as Al cap thickness, dead-layer thickness and Ge hole size) on optimum dimensions of marinelli beaker. In addition, the effects of detector material on optimal beaker dimensions were also investigated. Finally, the optimized beaker dimensions at various beaker volumes (300, 500, 700, 1000 and 1500 cm(3)) were determined for some conventional Ge detectors with different crystal sizes (16 sizes)...
March 21, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28340278/path-analysis-and-canonical-correlations-for-indirect-selection-of-jatropha-genotypes-with-higher-oil-yield
#16
L A Silva, L A Peixoto, P E Teodoro, E V Rodrigues, B G Laviola, L L Bhering
Jatropha is a species with great potential for biodiesel production, and the knowledge on how the main agronomic traits are correlated will contribute to its improvement. Therefore, the objectives of this study were to estimate the genetic parameters of the traits: plant height at 12 and 40 months, canopy projection on the row at 12 and 40 months, canopy projection between the row at 12 and 40 months, number of branches at 40 months, grain yield, and oil yield; to verify the existence of phenotypic correlation between these traits; to verify the influence of the morphological traits on oil yield by means of path analysis; and to evaluate the relationship between the productive traits in Jatropha and the morphological traits measured at different ages...
March 22, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28340276/multivariate-diallel-analysis-allows-multiple-gains-in-segregating-populations-for-agronomic-traits-in-jatropha
#17
P E Teodoro, E V Rodrigues, L A Peixoto, L A Silva, B G Laviola, L L Bhering
Jatropha is research target worldwide aimed at large-scale oil production for biodiesel and bio-kerosene. Its production potential is among 1200 and 1500 kg/ha of oil after the 4th year. This study aimed to estimate combining ability of Jatropha genotypes by multivariate diallel analysis to select parents and crosses that allow gains in important agronomic traits. We performed crosses in diallel complete genetic design (3 x 3) arranged in blocks with five replications and three plants per plot. The following traits were evaluated: plant height, stem diameter, canopy projection between rows, canopy projection on the line, number of branches, mass of hundred grains, and grain yield...
March 22, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28340178/morphometric-covariation-between-palatal-shape-and-skeletal-pattern-in-class-ii-growing-subjects
#18
Valeria Paoloni, Roberta Lione, Francesca Farisco, Demetrios J Halazonetis, Lorenzo Franchi, Paola Cozza
Objectives: To evaluate the patterns of covariation between palatal and craniofacial morphology in Class II subjects in the early mixed dentition by means of geometric morphometrics. Methods: A cross-sectional sample of 85 Class II subjects (44 females, 41 males; mean age 8.7 years ± 0.8) was collected retrospectively according to the following inclusion criteria: European ancestry (white), Class II skeletal relationship, Class II division 1 dental relationship, early mixed dentition, and prepubertal skeletal maturation...
March 14, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28339520/efficacy-of-bacillus-subtilis-and-bacitracin-methylene-disalicylate-on-growth-performance-digestibility-blood-metabolites-immunity-and-intestinal-microbiota-after-intramuscular-inoculation-with-escherichia-coli-in-broilers
#19
M Manafi, S Khalaji, M Hedayati, N Pirany
This experiment was conducted to evaluate the effect of Bacillus subtilis (BS) on broiler performance and health after intramuscular inoculation with E. coli and compare its effect with a growth promoter antibiotic. In a completely randomized design manner, 360 male Ross 308 chicks were divided into 6 treatments and 5 replicates of 12 chicks in each replicate. Experimental treatments included control diet, control + E. coli (0.5 mL of culture containing 108 CFU of E. coli/ml), control + 0.1% BS, control + 0...
October 6, 2016: Poultry Science
https://www.readbyqxmd.com/read/28339367/the-functional-significance-of-morphological-changes-in-the-dentitions-of-early-mammals
#20
Andrew J Conith, Michael J Imburgia, Alfred J Crosby, Elizabeth R Dumont
The Mesozoic marked a time of experimentation in the tooth morphology of early mammals. One particular experiment involved the movement of three points, or cusps, on the surface of a molar tooth from a line into a triangle. This transition is exemplified by two extinct insectivorous mammals, Morganucodon (cusps in a line) and Kuehneotherium (cusps in a triangle). Here we test whether this difference in cusp arrangement, alongside cusp heights and angles between cusps, is associated with differences in the ability of the teeth to fracture proxy-insect prey...
November 2016: Journal of the Royal Society, Interface
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