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paediatric neurosurgery

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https://www.readbyqxmd.com/read/28468670/the-effect-of-dexmedetomidine-on-cerebral-perfusion-and-oxygenation-in-healthy-piglets-with-normal-and-lowered-blood-pressure-anaesthetized-with-propofol-remifentanil-total-intravenous-anaesthesia
#1
Mai Louise Grandsgaard Mikkelsen, Rikard Ambrus, Rune Rasmussen, James Edward Miles, Helle Harding Poulsen, Finn Borgbjerg Moltke, Thomas Eriksen
BACKGROUND: During anaesthesia and surgery, in particular neurosurgery, preservation of cerebral perfusion and oxygenation (CPO) is essential for normal postoperative brain function. The isolated effects on CPO of either individual anaesthetic drugs or entire anaesthetic protocols are of importance in both clinical and research settings. Total intravenous anaesthesia (TIVA) with propofol and remifentanil is widely used in human neuroanaesthesia. In addition, dexmedetomidine is receiving increasing attention as an anaesthetic adjuvant in neurosurgical, intensive care, and paediatric patients...
May 3, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/28410792/accuracy-of-pecarn-catch-and-chalice-head-injury-decision-rules-in-children-a-prospective-cohort-study
#2
Franz E Babl, Meredith L Borland, Natalie Phillips, Amit Kochar, Sarah Dalton, Mary McCaskill, John A Cheek, Yuri Gilhotra, Jeremy Furyk, Jocelyn Neutze, Mark D Lyttle, Silvia Bressan, Susan Donath, Charlotte Molesworth, Kim Jachno, Brenton Ward, Amanda Williams, Amy Baylis, Louise Crowe, Ed Oakley, Stuart R Dalziel
BACKGROUND: Clinical decision rules can help to determine the need for CT imaging in children with head injuries. We aimed to validate three clinical decision rules (PECARN, CATCH, and CHALICE) in a large sample of children. METHODS: In this prospective observational study, we included children and adolescents (aged <18 years) with head injuries of any severity who presented to the emergency departments of ten Australian and New Zealand hospitals. We assessed the diagnostic accuracy of PECARN (stratified into children aged <2 years and ≥2 years), CATCH, and CHALICE in predicting each rule-specific outcome measure (clinically important traumatic brain injury [TBI], need for neurological intervention, and clinically significant intracranial injury, respectively)...
June 17, 2017: Lancet
https://www.readbyqxmd.com/read/28407334/time-to-cranial-computerised-tomography-for-acute-traumatic-brain-injury-in-paediatric-patients-effect-of-the-shorter-stays-in-emergency-departments-target-in-new-zealand
#3
Peter G Jones, Bridget Kool, Stuart Dalziel, Michael Shepherd, James Le Fevre, Alana Harper, Susan Wells, Joanna Stewart, Elana Curtis, Papaarangi Reid, Shanthi Ameratunga
AIM: Timely access to computerised tomography (CT) for acute traumatic brain injuries (TBIs) facilitates rapid diagnosis and surgical intervention. In 2009, New Zealand introduced a mandatory target for emergency department (ED) stay such that 95% of patients should leave ED within 6 h of arrival. This study investigated whether this target influenced the timeliness of cranial CT scanning in children who presented to ED with acute TBI. METHODS: We retrospectively reviewed a random sample of charts of children <15 years with acute TBI from 2006 to 2012...
April 13, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28247111/prospective-review-of-30-day-morbidity-and-mortality-in-a-paediatric-neurosurgical-unit
#4
REVIEW
Emer Campbell, Thomas Beez, Lorraine Todd
PURPOSE: The purpose of this study is to record the 30-day and inpatient morbidity and mortality in paediatric patients in a tertiary neuroscience centre over a 2-year period. The intentions were to establish the frequency of significant adverse events, review the current published rates of morbidity in paediatric neurosurgical patients and propose three clinical indicators for future comparison. METHODS: All deaths and adverse events were prospectively recorded from 1 January 2014 to 31 December 2015...
March 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28208985/pattern-of-inpatient-dermatology-consultations-in-a-tertiary-care-centre-from-northern-india
#5
Abhilasha Williams, Anuradha Bhatia, Bimal Kanish, Paulina Rose Chaudhary, Clarence James Samuel
INTRODUCTION: The importance of dermatology inpatient consultation is of significant importance yet is not well documented. AIM: To retrospectively analyse the spectrum of dermatology inpatient consultations from the various departments and to document the most commonly occurring dermatological disorders from each speciality. MATERIALS AND METHODS: This study was done in an 800 bedded premier teaching hospital in Ludhiana, Punjab, North Western India...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27822762/clinical-practice-audit-concerning-antimicrobial-prophylaxis-in-paediatric-neurosurgery-results-from-a-german-paediatric-oncology-unit
#6
Katja Weiss, Arne Simon, Norbert Graf, Jakob Schöpe, Joachim Oertel, Stefan Linsler
BACKGROUND: Perioperative antimicrobial prophylaxis (PAP) has been identified as an important target for internal audits, concerning the judicious use of antibiotics. Paediatric oncology patients with brain tumours face an increased risk of surgical site infection (SSI) after neurosurgery and receive routine PAP in this setting. PATIENTS AND METHODS: All patients younger than 18 years admitted to the paediatric oncology centre (POC) with a neurosurgical intervention...
January 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27778076/a-retrospective-one-year-estimation-of-the-volume-and-nature-of-surgical-and-anaesthetic-services-delivered-to-the-populations-of-the-fako-division-of-the-south-west-region-of-cameroon-an-urgent-call-for-action
#7
Alain Chichom-Mefire, Victor Mbome Njie, Vincent Verla, Julius Atashili
BACKGROUND: Surgery-related conditions account for the majority of admissions in primary referral hospitals in Sub-Saharan Africa. The role of surgery in the reduction of global disease burden is well recognized, but there is a great qualitative and quantitative disparity in the delivery of surgical and anaesthetic services between countries. This study aims at estimating the nature and volume of surgery delivered in an entire administrative division of Cameroon. METHODS: In this retrospective survey conducted during the year 2013, we used a standard tool to analyse the infrastructure and human resources involved in the delivery of surgical and anaesthetic services in the Fako division in the south-west region of Cameroon...
October 24, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27746701/regional-versus-general-anaesthesia-for-improved-cognitive-function-after-procedures-other-than-cardiac-surgery-or-neurosurgery-in-adult-and-paediatric-patients
#8
Michael H Andreae, Arthur Atchabahian, Aileen M McCrillis, Jerry Y Chao, Suzuko Suzuki, Shlomo Shinnar, Charles B Hall, Richard B Lipton
This is the protocol for a review and there is no abstract. The objectives are as follows: The objective of this review is to compare the effects of regional versus general anaesthesia on cognitive function after procedures other than cardiac surgery or neurosurgery in adult and in paediatric patients.
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27687144/neonatal-post-haemorrhagic-hydrocephalus-in-the-uk-a-survey-of-current-practice
#9
Naveen Kumar, Wisam Al-Faiadh, Jignesh Tailor, Conor Mallucci, Chris Chandler, Sanj Bassi, Benedetta Pettorini, Bassel Zebian
OBJECTIVES: The management of neonatal post-haemorrhagic hydrocephalus (nPHH) varies considerably between centres and even between neurosurgeons in the same centre. We performed a nationwide survey to evaluate current practice in the UK and reviewed the evidence for each intervention. METHODS: An online semi-structured questionnaire was emailed to all units registered on the British Paediatric Neurosurgery Group Mailing List. The survey consisted of 18 questions designed to establish the status quo in the management of nPHH, including preferred temporising procedure, factors guiding the timing of intervention and willingness to participate in a prospective study...
September 30, 2016: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/27666293/management-of-csf-leak-in-base-of-skull-fractures-in-adults
#10
REVIEW
See Yung Phang, Kathrin Whitehouse, Lucy Lee, Hisham Khalil, Paul McArdle, Peter C Whitfield
AIMS: CSF leaks are not uncommon after a base of skull fracture. Currently there is no standardised algorithm for the investigation and management of post-traumatic CSF leaks. In this paper we aim to provide an evidence-based framework for managing post-traumatic CSF leaks. METHODS: We searched the English literature over the past 45 years using CINAHL, EMBASE and MEDLINE for the terms (1) post-traumatic CSF leaks or fistulas, and (2) basilar or base of skull fractures, but excluded papers on post-operative and non-traumatic CSF leaks, and papers on paediatric post- traumatic CSF leaks...
December 2016: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/27659828/intra-operative-neurophysiological-mapping-and-monitoring-during-brain-tumour-surgery-in-children-an-update
#11
REVIEW
Angela Coppola, Vincenzo Tramontano, Federica Basaldella, Chiara Arcaro, Giovanna Squintani, Francesco Sala
INTRODUCTION: Over the past decade, the reluctance to operate in eloquent brain areas has been reconsidered in the light of the advent of new peri-operative functional neuroimaging techniques and new evidence from neuro-oncology. To maximise tumour resection while minimising morbidity should be the goal of brain surgery in children as much as it is in adults, and preservation of brain functions is critical in the light of the increased survival and the expectations in terms of quality of life...
October 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27569564/-syringomyelias-in-paediatrics-a-retrospective-study-of-25-cases
#12
I Martinez-Albaladejo, M Prochazkova, I Perez-Sebastian, B Bernardino-Cuesta, C Martinez-Ferrandez, O M Suarez-Traba, M Budke, J J Garcia-Penas
INTRODUCTION: Syringomyelia is defined as a cavity containing cerebrospinal fluid inside the spinal cord. AIM: To describe the clinical characteristics of a series of patients with syringomyelia, as well as its diagnosis and treatment. PATIENTS AND METHODS: We conducted a retrospective descriptive study by reviewing the medical records at our centre. RESULTS: We reviewed 25 patients diagnosed with syringomyelia. In five cases, the diagnosis was reached casually, and eight of them presented a previous severe pathology (tumour, bone or vascular)...
September 1, 2016: Revista de Neurologia
https://www.readbyqxmd.com/read/27526098/results-of-the-prophylactic-surgery-of-lumbosacral-lipomas-20%C3%A2-years-of-experience-in-the-paediatric-neurosurgery-department-la-timone-enfants-hospital-marseille-france
#13
Sandra Pérez da Rosa, Didier Scavarda, Maurice Choux
We conducted a retrospective study of children with lumbosacral lipomas treated in the Department of Pediatric Neurosurgery hospital Timone Enfants in the last 20 years. We selected patients with lipomas of the conus medullaris who underwent preventive surgery. 86 ,4 % of the patients remained asymptomatic during the follow-up. Worse results were observed in children older than one year old at surgery with transitional lipoma, with the conus medullaris was below L5 and when the resection had been partial...
November 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27418377/the-glasgow-outcome-scale-40-years-of-application-and-refinement
#14
REVIEW
Tom McMillan, Lindsay Wilson, Jennie Ponsford, Harvey Levin, Graham Teasdale, Michael Bond
The Glasgow Outcome Scale (GOS) was first published in 1975 by Bryan Jennett and Michael Bond. With over 4,000 citations to the original paper, it is the most highly cited outcome measure in studies of brain injury and the second most-cited paper in clinical neurosurgery. The original GOS and the subsequently developed extended GOS (GOSE) are recommended by several national bodies as the outcome measure for major trauma and for head injury. The enduring appeal of the GOS is linked to its simplicity, short administration time, reliability and validity, stability, flexibility of administration (face-to-face, over the telephone and by post), cost-free availability and ease of access...
August 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27416574/glioblastoma-and-abo-blood-groups-further-evidence-of-an-association-between-the-distribution-of-blood-group-antigens-and-brain-tumours
#15
Mohammed Z Allouh, Mohammed M Al Barbarawi, Mohammad Y Hiasat, Mohammed A Al-Qaralleh, Emad I Ababneh
BACKGROUND: Glioblastoma is a highly malignant brain tumour that usually leads to death. Several studies have reported a link between the distribution of ABO blood group antigens and a risk of developing specific types of cancer, although no consensus has been reached. This study aims to investigate the relationship between the distribution of ABO blood group antigens and the incidence of glioblastoma. MATERIALS AND METHODS: The study cohort consisted of 115 glioblastoma patients who were diagnosed at King Abdullah University Hospital, Jordan, between 2004 and 2015...
June 30, 2016: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27400755/paediatric-recreational-vehicle-related-head-injuries-presenting-to-the-emergency-department-of-a-major-paediatric-trauma-centre-in-australia-is-there-room-for-improvement
#16
Silvia Bressan, Marco Daverio, Ruth Barker, Charlotte Molesworth, Franz E Babl
OBJECTIVE: This study examines clinical characteristics and helmet use of children presenting to the ED with a recreational vehicle (RV)-related head injury (HI). METHODS: Observational retrospective study of children <18 years presenting with a RV-related HI to the ED of a state-wide paediatric trauma centre in Australia between April 2011 and January 2014. RESULTS: In the 647 presentations identified, corresponding to 7.5% (95% CI 7...
August 2016: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/27161098/learning-from-lawsuits-ten-years-of-nhs-litigation-authority-claims-against-11-surgical-specialities-in-england
#17
Kathryn E Ford, Lilli R L Cooper
INTRODUCTION: Medico-legal claims are a drain on NHS resources and promote defencive practice. The litigious burden of surgery in England has not been previously described. This paper describes trends over ten years of claims made against the NHS across 11 surgical specialities. MATERIALS AND METHODS: Data were requested for all claims received by the NHS Litigation Authority (NHSLA) from 2004 to 2014. Surgical specialities included cardiothoracic, general, neurosurgery, obstetric, oral and maxillofacial (OMFS), orthopaedic, otorhinolaryngology, paediatric, plastic, urology and vascular surgery...
May 6, 2016: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/26926894/oncology-referral-concerning-paediatric-neurosurgery-analysis-of-the-situation-between-2008-2013-in-the-north-of-portugal
#18
Ana Batista, Luís Nogueira-Silva, Rui Vaz, Joana Oliveira
INTRODUCTION: Primary central nervous system tumours represent the second most frequent neoplasm and are the leading cause of death from solid tumours in children. Our study aimed to provide the most up-to-date epidemiological analysis of primary central nervous system tumours in children living in the north of Portugal and to explore a possible effect of the centralisation of care on outcomes. MATERIAL AND METHODS: This population-based study included all newly diagnosed and histologically confirmed primary central nervous system tumours in people below 18 years old, living in the north of Portugal, from January 2008 to December 2013...
January 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/26913859/late-post-traumatic-epilepsy-in-children-and-young-adults-impropriety-of-long-term-antiepileptic-prophylaxis-and-risks-in-tapering
#19
Sandra Strazzer, Marco Pozzi, Paolo Avantaggiato, Nicoletta Zanotta, Roberta Epifanio, Elena Beretta, Francesca Formica, Federica Locatelli, Sara Galbiati, Emilio Clementi, Claudio Zucca
BACKGROUND: After traumatic brain injury, epilepsy affects up to 20 % of children. It is a risk factor, for both clinical recovery and cognitive performance; therefore pharmacological therapy is advisable. Current guidelines recommend prophylaxis to be initiated as soon as possible and tapered 1 week after trauma. However, no guideline exists for paediatric patients and the clinical practice is heterogeneous. OBJECTIVE: In our institute, prophylaxis was routinely tapered 6 months after trauma...
June 2016: Paediatric Drugs
https://www.readbyqxmd.com/read/26908533/a-prospective-surveillance-of-paediatric-head-injuries-in-singapore-a-dual-centre-study
#20
MULTICENTER STUDY
Shu-Ling Chong, Su Yah Chew, Jasmine Xun Yi Feng, Penny Yun Lin Teo, Sock Teng Chin, Nan Liu, Marcus Eng Hock Ong
OBJECTIVE: To study the causes of head injuries among the paediatric population in Singapore, and the association between causes and mortality, as well as the need for airway or neurosurgical intervention. DESIGN: This is a prospective observational study utilising data from the trauma surveillance system from January 2011 to March 2015. SETTING: Paediatric emergency departments (EDs) of KK Women's and Children's Hospital and the National University Health System...
February 23, 2016: BMJ Open
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