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https://www.readbyqxmd.com/read/29753888/mobility-and-satisfaction-with-a-microprocessor-controlled-knee-in-moderately-active-amputees-a-multi-centric-randomized-crossover-trial
#1
Céline Lansade, Eric Vicaut, Jean Paysant, Doménico Ménager, Marie-Christine Cristina, Frank Braatz, Stephan Domayer, Dominic Pérennou, Gérard Chiesa
OBJECTIVE: Microprocessor-controlled knees are generally prescribed and reimbursed for active amputees. Recent studies suggested that this technology could be useful for amputees with moderate activity level. We compared the efficiency of a microprocessor-controlled knee (MPK, Kenevo, Otto Bock) and non-MPKs (NMPKs) in these indications. METHODS: A multi-centric randomized crossover trial was conducted in 16 hospitals from 3 European countries. Participants were randomized to an MPK-NMPK sequence, testing the MPK for 3 months and the NMPK for 1 month, or to an NMPK-MPK sequence, testing the NMPK for 1 month and the MPK for 3 months...
May 10, 2018: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29734333/a-coupled-process-of-same-and-opposite-sex-mating-generates-polyploidy-and-genetic-diversity-in-candida-tropicalis
#2
Han Du, Qiushi Zheng, Jian Bing, Richard J Bennett, Guanghua Huang
Sexual reproduction is a universal mechanism for generating genetic diversity in eukaryotes. Fungi exhibit diverse strategies for sexual reproduction both in nature and in the laboratory. In this study, we report the discovery of same-sex (homothallic) mating in the human fungal pathogen Candida tropicalis. We show that same-sex mating occurs between two cells carrying the same mating type (MTLa/a or α/α) and requires the presence of pheromone from the opposite mating type as well as the receptor for this pheromone...
May 7, 2018: PLoS Genetics
https://www.readbyqxmd.com/read/29487859/ph-homeostasis-links-the-nutrient-sensing-pka-torc1-sch9-m%C3%A3-nage-%C3%A3-trois-to-stress-tolerance-and-longevity
#3
REVIEW
Marie-Anne Deprez, Elja Eskes, Tobias Wilms, Paula Ludovico, Joris Winderickx
The plasma membrane H+ -ATPase Pma1 and the vacuolar V-ATPase act in close harmony to tightly control pH homeostasis, which is essential for a vast number of physiological processes. As these main two regulators of pH are responsive to the nutritional status of the cell, it seems evident that pH homeostasis acts in conjunction with nutrient-induced signalling pathways. Indeed, both PKA and the TORC1-Sch9 axis influence the proton pumping activity of the V-ATPase and possibly also of Pma1. In addition, it recently became clear that the proton acts as a second messenger to signal glucose availability via the V-ATPase to PKA and TORC1-Sch9...
January 12, 2018: Microbial Cell
https://www.readbyqxmd.com/read/29381371/new-plots-in-the-partnerships-of-contemporary-stemi-care-revival-of-the-m%C3%A3-nage-%C3%A3-trois
#4
Marc A Brouwer, Menko-Jan de Boer
No abstract text is available yet for this article.
January 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29356668/commodit%C3%A3-s-familiales-et-sant%C3%A3-des-enfants-de-moins-de-cinq-ans-en-ha%C3%A3-ti
#5
Isabelle Roy, Barthélémy Kuate Defo
OBJECTIFS: Évaluer le rôle des commodités familiales dans l'occurrence de la diarrhée chez les enfants de moins de 5 ans en Haïti, selon leur type (eau potable, toilettes et réfrigérateur) et leur nombre.MÉTHODE : Nous avons mis en commun les données de quatre Enquêtes démographiques et de santé réalisées en Haïti entre 1994-1995 et 2012. Nous avons retenu un échantillon de 14 481 enfants de 1-59 mois. Nous avons évalué le rôle des commodités familiales dans l'occurrence de la diarrhée selon le groupe d'âge d'enfants à risque (1-5; 6-11; 12-23; 24-59 mois), au moyen des modèles de régression logistique...
January 22, 2018: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/29224240/phototherapy-in-france-quantitative-data-2007-2016-from-the-national-health-insurance-register
#6
LETTER
F Aubin, J Courtois, E Puzenat, C Nardin, F Castelain, F Pelletier, C Gastaldi-Ménager
No abstract text is available yet for this article.
December 10, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29193370/valence-localization-at-a-bio-inspired-mixed-valent-cu-2-s-2-motif-upon-solvation-in-acetonitrile-effect-on-nitrous-oxide-reductase-n-2-or-activity
#7
Charlène Esmieu, Maylis Orio, Jordan Mangue, Jacques Pécaut, Stéphane Ménage, Stéphane Torelli
We demonstrate, based on experimental and theoretical evidence, that the isolated [2(CH3 CN)2 ]2+ complex prepared in CH3 CN and containing a mixed-valent {Cu2 II,I S} core evolves towards a new [2(CH3 CN)3 ]2+ species upon solvation in CH3 CN. Unlike its type III structural analogue [2(H2 O)(OTf)]+ active toward N2 O reduction, this new type I compound is inactive. This outcome opens new perspectives for a rational for N2 O activation using bio-inspired Cu/S complexes, especially on the role of the valence localization/delocalization and the Cu-Cu bond on the reactivity...
April 6, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29148757/cross-linked-artificial-enzyme-crystals-as-heterogeneous-catalysts-for-oxidation-reactions
#8
Sarah Lopez, Laurianne Rondot, Chloé Leprêtre, Caroline Marchi-Delapierre, Stéphane Ménage, Christine Cavazza
Designing systems that merge the advantages of heterogeneous catalysis, enzymology, and molecular catalysis represents the next major goal for sustainable chemistry. Cross-linked enzyme crystals display most of these essential assets (well-designed mesoporous support, protein selectivity, and molecular recognition of substrates). Nevertheless, a lack of reaction diversity, particularly in the field of oxidation, remains a constraint for their increased use in the field. Here, thanks to the design of cross-linked artificial nonheme iron oxygenase crystals, we filled this gap by developing biobased heterogeneous catalysts capable of oxidizing carbon-carbon double bonds...
December 13, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29098586/on-the-tracks-of-sandarac-review-and-chemical-analysis
#9
Clara Azémard, Matthieu Ménager, Cathy Vieillescazes
The sandarac resin (Tetraclinis articulata) has been long used for its properties, mostly as a varnish component. Called juniper resin until the nineteenth century, the real botanical origin of sandarac is still unclear. The first approach to this issue is the review of the evolution of the etymology, terminology, and botanical description of sandarac through time. It seems that sandarac was mainly coming from T. articulata but the use of some juniper resins before the twentieth century is not to be excluded...
December 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29067314/sar110894-a-potent-histamine-h3-receptor-antagonist-displays-disease-modifying-activity-in-a-transgenic-mouse-model-of-tauopathy
#10
Philippe Delay-Goyet, Véronique Blanchard, Nathalie Schussler, Mati Lopez-Grancha, Jean Ménager, Véronique Mary, Eric Sultan, Armelle Buzy, Jean-Claude Guillemot, Jeanne Stemmelin, Philippe Bertrand, Thomas Rooney, Laurent Pradier, Pascal Barnéoud
INTRODUCTION: Tau hyperphosphorylation and neurofibrillary tangles are histopathologic hallmarks of tauopathies. Histamine H3-receptor antagonists have been proposed to reduce tau hyperphosphorylation in preclinical models. METHODS: We evaluated the ability of SAR110894, a selective histamine H3-receptor antagonist, to inhibit tau pathology and prevent cognitive deficits in a tau transgenic mouse model (THY-Tau22). RESULTS: SAR110894 treatment for 6 months (but not 2 weeks) in THY-Tau22 mice decreased both tau hyperphosphorylation at pSer396-pSer404 (AD2 signal) in the hippocampus and the number of AT8 (pSer199/202-Thr205) positive cells in the cortex and decreased the formation of neurofibrillary tangles in the cortex, hippocampus, and amygdala...
November 2016: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29029028/intralobar-pulmonary-sequestration-with-an-aortic-aneurysm
#11
Jean-Baptiste Menager, Olaf Mercier
No abstract text is available yet for this article.
March 1, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28967233/overhydration-underhydration-and-total-body-sodium-a-tricky-m%C3%A3-nage-a-trois-in-dialysis-patients
#12
EDITORIAL
Luminita Voroneanu, Cristina Gavrilovici, Adrian Covic
Overhydration is a frequent complication in dialysis patients. It has been linked with hypertension, left ventricular hypertrophy, arterial stiffness, atherosclerosis uremic cardiomyopathy, and all-cause mortality or cardiovascular morbidity. In addition, predialysis underhydration is also associated with increased risk of death in ESRD patients. In this context, the optimal evaluation of hydration status is a must. However, this mission is not easy or accurate. In the last 10 years, several new methods have been tested in dialysis patients, particularly bioimpedance and lung ultrasonography...
January 2018: Seminars in Dialysis
https://www.readbyqxmd.com/read/28830875/influences-of-breakfast-on-clock-gene-expression-and-postprandial-glycemia-in-healthy-individuals-and-individuals-with-diabetes-a-randomized-clinical-trial
#13
RANDOMIZED CONTROLLED TRIAL
Daniela Jakubowicz, Julio Wainstein, Zohar Landau, Itamar Raz, Bo Ahren, Nava Chapnik, Tali Ganz, Miriam Menaged, Maayan Barnea, Yosefa Bar-Dayan, Oren Froy
OBJECTIVE: The circadian clock regulates glucose metabolism by mediating the activity of metabolic enzymes, hormones, and transport systems. Breakfast skipping and night eating have been associated with high HbA1c and postprandial hyperglycemia after lunch and dinner. Our aim was to explore the acute effect of breakfast consumption or omission on glucose homeostasis and clock gene expression in healthy individuals and individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS: In a crossover design, 18 healthy volunteers and 18 volunteers with 14...
November 2017: Diabetes Care
https://www.readbyqxmd.com/read/28810353/living-as-a-couple-with-anorexia-nervosa-a-dyadic-interpretative-phenomenological-analysis
#14
Pascal Antoine, Bérengère Flinois, Karyn Doba, Jean-Louis Nandrino, Vincent Dodin, Marion Hendrickx
This study examined the difficulties couples face in relation to anorexia nervosa. Using interpretative phenomenological analysis, five couples in which one of the partners lives with anorexia nervosa were interviewed separately. The findings are conceptualized into three areas: first, the encounter 'at the crossroads between remission and relapse'; second, the way that 'anorexia reveals itself'; and finally, the way the 'ménage à trois' works, including the illness fully as part of the couple. Psychotherapists should take into account the context of the couple and the complex interaction between the couple and the illness to support both partners' development of appropriate responses...
October 1, 2016: Journal of Health Psychology
https://www.readbyqxmd.com/read/28756037/value-of-a-national-administrative-database-to-guide-public-decisions-from-the-syst%C3%A3-me-national-d-information-interr%C3%A3-gimes-de-l-assurance-maladie-sniiram-to-the-syst%C3%A3-me-national-des-donn%C3%A3-es-de-sant%C3%A3-snds-in-france
#15
REVIEW
P Tuppin, J Rudant, P Constantinou, C Gastaldi-Ménager, A Rachas, L de Roquefeuil, G Maura, H Caillol, A Tajahmady, J Coste, C Gissot, A Weill, A Fagot-Campagna
In 1999, French legislators asked health insurance funds to develop a système national d'information interrégimes de l'Assurance Maladie (SNIIRAM) [national health insurance information system] in order to more precisely determine and evaluate health care utilization and health care expenditure of beneficiaries. These data, based on almost 66 million inhabitants in 2015, have already been the subject of numerous international publications on various topics: prevalence and incidence of diseases, patient care pathways, health status and health care utilization of specific populations, real-life use of drugs, assessment of adverse effects of drugs or other health care procedures, monitoring of national health insurance expenditure, etc...
October 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/28736780/surface-initiated-synthesis-of-bulk-imprinted-magnetic-polymers-for-protein-recognition
#16
Charlotte Boitard, Anne-Laure Rollet, Christine Ménager, Nébéwia Griffete
Bulk imprinting of proteins was used combined with a grafting approach onto maghemite nanoparticles to develop a faster and simpler polymerization method for the synthesis of magnetic protein imprinted polymers with very high adsorption capacities and very strong affinity constants.
August 3, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28730846/spectral-behavior-of-white-pigment-mixtures-using-reflectance-ultraviolet-fluorescence-spectroscopy-and-multispectral-imaging
#17
Lucilla Pronti, Anna Candida Felici, Matthieu Ménager, Cathy Vieillescazes, Mario Piacentini
Reflectance spectroscopy, ultraviolet (UV)-fluorescence spectroscopy, and multispectral imaging have been widely employed for pigment identification on paintings. From ancient times to the present, lead white, zinc white, and titanium white have been the most important white pigments used for paintings and they are used as pigment markers for dating a work of art. The spectral behavior of these pigments is reported in several scientific papers and websites, but those of their mixtures are quite unknown. We present a combined nondestructive approach for identifying mixtures of lead white, zinc white, and titanium white as powder and dispersed in two different binder media (egg yolk and linseed oil) by using reflectance spectroscopy, spectrofluorimetry, multispectral reflectance and UV-fluorescence imaging...
December 2017: Applied Spectroscopy
https://www.readbyqxmd.com/read/28723064/doxorubicin-intracellular-remote-release-from-biocompatible-oligo-ethylene-glycol-methyl-ether-methacrylate-based-magnetic-nanogels-triggered-by-magnetic-hyperthermia
#18
Esther Cazares-Cortes, Ana Espinosa, Jean-Michel Guigner, Aude Michel, Nébéwia Griffete, Claire Wilhelm, Christine Ménager
Hybrid nanogels, composed of thermoresponsive polymers and superparamagnetic nanoparticles, are attractive nanocarriers for biomedical applications, being able-as a polymer matrix-to uptake and release high quantities of chemotherapeutic agents and-as magnetic nanoparticles-to be heated when exposed to an alternative magnetic field (AMF), better known as magnetic hyperthermia. Herein, biocompatible, pH-responsive, magnetoresponsive, and thermoresponsive nanogels, based on oligo(ethylene glycol) methyl ether methacrylate monomers and a methacrylic acid comonomer were prepared by conventional precipitation radical copolymerization in water, post-assembled by complexation with iron oxide magnetic nanoparticles (MNPs) of maghemite (γ-Fe2O3), and loaded with an anticancer drug (doxorubicin, DOX), for remotely controlled drug release by a "hot spot", as an athermal magnetic hyperthermia strategy against cancer...
August 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28697041/circulating-osteoprotegerin-in-postmenopausal-osteoporotic-women-marker-of-impaired-glucose-regulation-or-impaired-bone-metabolism
#19
Margarita Mashavi, Miriam Menaged, Marina Shargorodsky
OBJECTIVE: Osteoprotegerin (OPG) is closely related to insulin resistance and bone remodeling. However, no studies have examined the role of OPG in postmenopausal women with coexistent impaired glucose and bone regulation. The present study investigated the relationship of OPG to glucose homeostasis and insulin resistance in postmenopausal osteoporotic women with different types of glucose tolerance. METHODS: In all, 114 postmenopausal osteoporotic women were divided into three groups according to glucose tolerance status: 51 with normal glucose tolerance (NGT, group 1), 31 with impaired glucose tolerance (IGT, group 2), and 32 with type 2 diabetes mellitus (DM, group 3)...
November 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28692392/evaluation-of-a-novel-syndromic-surveillance-query-for-heat-related-illness-using-hospital-data-from-maricopa-county-arizona-2015
#20
Jessica R White, Vjollca Berisha, Kathryn Lane, Henri Ménager, Aaron Gettel, Carol R Braun
OBJECTIVES: We evaluated a novel syndromic surveillance query, developed by the Council of State and Territorial Epidemiologists (CSTE) Heat Syndrome Workgroup, for identifying heat-related illness cases in near real time, using emergency department and inpatient hospital data from Maricopa County, Arizona, in 2015. METHODS: The Maricopa County Department of Public Health applied 2 queries for heat-related illness to area hospital data transmitted to the National Syndromic Surveillance Program BioSense Platform: the BioSense "heat, excessive" query and the novel CSTE query...
July 2017: Public Health Reports
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