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https://www.readbyqxmd.com/read/28811947/solitary-skull-metastasis-as-the-first-presentation-of-a-metachronous-primary-lung-cancer-in-a-survivor-from-pancreatic-cancer
#1
Ali Altalhy, Yazid Maghrabi, Zuhoor Almansouri, Saleh S Baeesa
Skull metastasis from lung cancer is relatively common, yet the first presentation for this malignant disease is a rare occurrence. We herein report a case of a 54-year-old female, who had a good outcome following Whipple procedure for periampullary adenocarcinoma five years before her current presentation. During a routine follow-up, she was found to have a slowly progressive painless right parietal swelling. The systemic screening workup revealed no abdominal disease, but a solitary pulmonary nodule was identified...
2017: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/28803860/intestinal-permeability-changes-systemic-endotoxemia-inflammatory-serum-markers-and-sepsis-after-whipple-s-operation-for-carcinoma-of-the-pancreas-head
#2
Mario Schietroma, Beatrice Pessia, Francesco Carlei, Gianfranco Amicucci
POURPOSE: The aim was to evaluate the relationship between failure of gut barrier function, inflammatory markers and septic complications after pancreatoduodenectomy for pancreatic adenocarcinoma. METHODOLOGY: 44 patients were enrolled in this prospective observational clinical study and underwent curative open pancreatoduodenectomy for adenocarcinoma of the head of the pancreas. All patients underwent assessment of intestinal permeability using the lactulose/manitol excretions ratios (L/M ratio), endotoxemia, IL-1β, IL-6, CRP, and elastase levels before surgery and on postoperative days 1, 3 and 7...
July 29, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28797345/vascular-resections-during-the-whipple-procedure
#3
REVIEW
Warren R Maley, Charles J Yeo
No abstract text is available yet for this article.
September 2017: Advances in Surgery
https://www.readbyqxmd.com/read/28777473/bibliometric-analysis-of-female-authorship-trends-and-collaboration-dynamics-over-jbmr%C3%A2-s-30-year-history
#4
Austin E Wininger, James P Fischer, Elive F Likine, Andrew S Gudeman, Alexander R Brinker, Jonathan Ryu, Kevin A Maupin, Shatoria Lunsford, Elizabeth C Whipple, Randall T Loder, Melissa A Kacena
In academia, authorship is considered a currency, and is important for career advancement. As the Journal of Bone and Mineral Research (JBMR®) is the highest-ranked journal in the field of bone, muscle, and mineral metabolism, and is the official publication of the American Society for Bone and Mineral Research, we sought to examine authorship changes over JBMR®'s 30-year history. Two bibliometric methods were used to collect the data. The "decade method" included all published manuscripts throughout one year in each decade over the past 30 years starting with the inaugural year, yielding 746 manuscripts for analysis...
August 4, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28770535/cytology-of-cerebrospinal-fluid-in-cns-whipple-disease
#5
Marina Boban, Koraljka Gjadrov-Kuveždić, Jasminka Jakić-Razumović
No abstract text is available yet for this article.
August 2, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28761367/protein-losing-enteropathy-comprehensive-review-of-the-mechanistic-association-with-clinical-and-subclinical-disease-states
#6
REVIEW
David G Levitt, Michael D Levitt
Protein losing enteropathy (PLE) has been associated with more than 60 different conditions, including nearly all gastrointestinal diseases (Crohn's disease, celiac, Whipple's, intestinal infections, and so on) and a large number of non-gut conditions (cardiac and liver disease, lupus, sarcoidosis, and so on). This review presents the first attempt to quantitatively understand the magnitude of the PLE in relation to the associated pathology for three different disease categories: 1) increased lymphatic pressure (e...
2017: Clinical and Experimental Gastroenterology
https://www.readbyqxmd.com/read/28757865/emergency-backwards-whipple-for-bleeding-formidable-and-definitive-surgery
#7
Cristian Lupascu, Ana Trofin, Mihai Zabara, Alexandra Vornicu, Ramona Cadar, Nutu Vlad, Oana Apopei, Valentin Grigorean, Corina Lupascu-Ursulescu
INTRODUCTION: During the past decades, the safety of pancreatoduodenectomy has improved, with low mortality and reduced morbidity, particularly in centers with extensive experience. Emergency pancreatoduodenectomy is an uncommon event, for treatment of pancreaticoduodenal trauma, bleeding, or perforation. We herein present a single center experience concerning nontrauma emergency pancreatoduodenectomy for pancreaticoduodenal bleeding. METHODS: From January 2007 to December 2015, from a population of 134 PD (70 males and 64 females, mean age 62...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28744253/novel-eye-movement-disorders-in-whipple-s-disease-staircase-horizontal-saccades-gaze-evoked-nystagmus-and-esotropia
#8
Aasef G Shaikh, Fatema F Ghasia
Whipple's disease, a rare systemic infectious disorder, is complicated by the involvement of the central nervous system in about 5% of cases. Oscillations of the eyes and the jaw, called oculo-masticatory myorhythmia, are pathognomonic of the central nervous system involvement but are often absent. Typical manifestations of the central nervous system Whipple's disease are cognitive impairment, parkinsonism mimicking progressive supranuclear palsy with vertical saccade slowing, and up-gaze range limitation. We describe a unique patient with the central nervous system Whipple's disease who had typical features, including parkinsonism, cognitive impairment, and up-gaze limitation; but also had diplopia, esotropia with mild horizontal (abduction more than adduction) limitation, and vertigo...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28724483/using-white-tailed-deer-odocoileus-virginianus-in-infectious-disease-research
#9
Mitchell V Palmer, Rebecca J Cox, W Ray Waters, Tyler C Thacker, Diana L Whipple
Between 1940 and 2004, more than 335 emerging infectious disease events were reported in the scientific literature. The majority (60%) of these events involved zoonoses, most of which (72%) were of wildlife origin or had an epidemiologically important wildlife host. Because this trend of increasing emerging diseases likely will continue, understanding the pathogenesis, transmission, and diagnosis of these diseases in the relevant wildlife host is paramount. Achieving this goal often requires using wild animals as research subjects, which are vastly different from the traditional livestock or laboratory animals used by most universities and institutions...
July 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28693619/successful-pregnancy-after-mucinous-cystic-neoplasm-with-invasive-carcinoma-of-the-pancreas-in-a-patient-with-polycystic-ovarian-syndrome-a-case-report
#10
Conisha Holloman, S J Carlan, Lohini Sundharkrishnan, Angela Guzman, Mario Madruga
BACKGROUND: The incidence of invasive cancer within a mucinous cystic neoplasm of the pancreas varies between 6 and 36%. Polycystic ovarian syndrome is a disorder characterized by hyperandrogenism and anovulatory infertility. One surgical treatment that can restore endocrine balance and ovulation in polycystic ovarian syndrome is partial ovarian destruction. Successful pregnancies following preconception pancreaticoduodenectomies (Whipple procedures) and chemoradiation to treat pancreatic neoplasms have been reported rarely but none were diagnosed with pre-cancer polycystic ovarian syndrome-associated infertility...
July 11, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28691008/fluorescence-in-situ-hybridization-for-diagnosis-of-whipple-s-disease-in-formalin-fixed-paraffin-embedded-tissue
#11
Peter Braubach, Torsten Lippmann, Didier Raoult, Jean-Christophe Lagier, Ioannis Anagnostopoulos, Steffen Zender, Florian Peter Länger, Hans-Heinrich Kreipe, Mark Philipp Kühnel, Danny Jonigk
Whipple's disease (WD) is a rare chronic systemic infection with a wide range of clinical symptoms, routinely diagnosed in biopsies from the small intestine and other tissues by periodic acid-Schiff (PAS) diastase staining and immunohistological analysis with specific antibodies. The aim of our study was to improve the pathological diagnosis of WD. Therefore, we analyzed the potential of fluorescence in situ hybridization (FISH) for diagnosing WD, using a Tropheryma (T.) whipplei-specific probe. 19 formalin-fixed paraffin-embedded (FFPE) duodenal biopsy specimens of 12 patients with treated (6/12) and untreated (6/12) WD were retrospectively examined using PAS diastase staining, immunohistochemistry, and FISH...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28672119/an-unusual-cause-of-recurrent-gastrointestinal-bleeding-after%C3%A2-whipple-s-surgery
#12
Saeed Ali, Asad Ur Rahman, Udayakumar Navaneethan
No abstract text is available yet for this article.
August 2017: Gastroenterology
https://www.readbyqxmd.com/read/28672046/erratum-to-the-impact-of-stimulus-presentation-and-size-on-preference
#13
James W Moore, Keith C Radley, Evan H Dart, Heather M Whipple, Emily J Ness, Ashley N Murphy, Chris Furlow, Joy K Wimberly, Ashley Smith
[This corrects the article DOI: 10.1007/s40617-016-0148-6.].
March 2017: Behavior Analysis in Practice
https://www.readbyqxmd.com/read/28660130/mesenteric-lymphadenitis-as-a-presenting-feature-of-whipple-s-disease
#14
Mwelwa Chizinga, Danise Schiliro, Brett Mullin, Rashida La Barrie
Detecting Whipple's disease, a "great imitator", requires a high index of suspicion so that antimicrobial treatment can be initiated in a timely manner; a missed diagnosis can be fatal. Although an uncommon cause, Whipple's disease must be considered in adults with mesenteric lymphadenitis. We report the case of a 39-year-old African American man who presented with chronic joint pain, chronic weight loss, and acute onset epigastric pain. Contrast-enhanced computed tomography of the abdomen and pelvis showed extensive mesenteric lymphadenopathy...
2017: IDCases
https://www.readbyqxmd.com/read/28653162/completely-intracorporeal-handsewn-laparoscopic-anastomoses-during-whipple-procedure
#15
Giovanni Dapri, Nigel Antonio Bascombe, Leonardo Gerard, Carla Samaniego Ballart, Carlos Gimenez Viñas, Sven Saussez
BACKGROUND: Whipple procedure has been described since 1935,1 using classic open surgery. With the advent of minimally invasive surgery (MIS), it has been described to be feasible using the latest technology.2 (,) 3 In this video the authors report a full laparoscopic Whipple procedure, realizing the three anastomoses by intracorporeal handsewn method. VIDEO: A 70-year-old man who presented with adenocarcinoma of the ampulla of Vater, infiltrating the pancreatic parenchyma underwent to a laparoscopic Whipple...
June 26, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28652415/solid-pseudopapillary-tumor-of-the-pancreas-a-single-center-experience-and-review-of-the-literature
#16
REVIEW
Efstathios A Antoniou, Christos Damaskos, Nikolaos Garmpis, Christos Salakos, Giorgos-Antonios Margonis, Konstantinos Kontzoglou, Stefanos Lahanis, Eleftherios Spartalis, Dimitrios Patsouras, Stylianos Kykalos, Anna Garmpi, Nikolaos Andreatos, Timothy M Pawlik, Gregory Kouraklis
BACKGROUND: Solid pseudopapillary tumors (SPTs) of the pancreas are a rare occurrence, not exceeding 1-2% of all exocrine pancreatic tumors. SPT was first described in 1959 as "papillary tumor of the pancreas, benign or malignant" and affects mainly young women, in their second or third decade of age. These tumors are of low malignant potential, unclear pathogenesis, grow gradually and become considerably large before causing symptoms. A typical clinical presentation is often described by affected patients and, in some cases, an SPT is an incidental finding during the time the patient undergoes medical imaging studies for other health issues...
July 2017: In Vivo
https://www.readbyqxmd.com/read/28633596/laparotomy-site-implantation-metastasis-of-carcinoma-of-the-papilla-of-vater
#17
Milan Radojkovic, Jasmina Gligorijevic, Miroslav Stojanovic, Goran Stanojevic, Ivan Ilic
Introduction Carcinomas of the papilla of Vater make up a heterogeneous group of tumours arising from different types of epithelium. Regional lymph nodes, liver and lungs are the primary sites of metastatic progression of these tumours. Case presentation We present a patient with an abdominal incision site metastasis of low-grade (mixed type) adenocarcinoma of the papilla of Vater one year after pylorus-preserving pancreaticoduodenectomy. Implantation metastasis of low-grade ampullary carcinoma in the laparotomy wound after open Whipple's procedure is unusual...
January 1, 2017: Scottish Medical Journal
https://www.readbyqxmd.com/read/28630822/the-impact-of-stimulus-presentation-and-size-on-preference
#18
James W Moore, Keith C Radley, Evan H Dart, Heather M Whipple, Emily J Ness, Ashley N Murphy, Chris Furlow, Joy K Wimberly, Ashley Smith
The impact of stimulus size and presentation on choice during a preference assessment was investigated using a modified multiple-stimulus without replacement (MSWO) technique. Stimuli were either presented with a uniform magnitude, as determined by mass, or in a manner consistent with caregiver report of reinforcer consumption. While both assessment procedures identified the same top three preferred items in three out of five cases, greater variability in the preference rank of less preferred items was observed between assessments...
June 2017: Behavior Analysis in Practice
https://www.readbyqxmd.com/read/28623706/primary-inferior-vena-cava-smooth-muscle-tumor-with-diffuse-bizarre-giant-nuclei-and-low-mitotic-rate-a-nomenclatural-conundrum
#19
Runjan Chetty, Sangeetha N Kalimuthu, Hanna-Riikka Heinonen
A male patient with obstructive jaundice was found to have an incidental nodule within the inferior vena cava (IVC), below the level of the renal vein, on abdominal imaging. At the time of the Whipple's procedure for pancreatic adenocarcinoma, the IVC mass measuring 3.4×2.7×2.2 cm was also removed. Histologically, the lesion was well circumscribed, composed focally of spindle-shaped cells with cigar-shaped nuclei reminiscent of smooth muscle and a dominant pervasive, pleomorphic, bizarre giant cell component...
June 4, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28622620/simultaneous-uhplc-uv-analysis-of-hydroxychloroquine-minocycline-and-doxycycline-from-serum-samples-for-the-therapeutic-drug-monitoring-of-q-fever-and-whipple-s-disease
#20
Nicholas Armstrong, Magali Richez, Didier Raoult, Eric Chabriere
A fast UHPLC-UV method was developed for the simultaneous analysis of Hydroxychloroquine, Minocycline and Doxycycline drugs from 100μL of human serum samples. Serum samples were extracted by liquid-liquid extraction and injected into a phenyl hexyl reverse phase column. Compounds were separated using a mobile phase linear gradient and monitored by UV detection at 343nm. Chloroquine and Oxytetracycline were used as internal standards. Lower and upper limits of quantifications, as well as the other levels of calibration, were validated with acceptable accuracy (<15% deviation) and precision (<15% coefficient of variation) according to the European Medicines Agency guidelines...
June 9, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
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