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https://www.readbyqxmd.com/read/29906575/sodium-fluorescein-video-angiography-fl-vag-as-an-adjunct-to-resection-of-cerebral-arteriovenous-malformations
#1
Serrano-Rubio Alejandro, Ruiz-Treviño Armando S, Orenday-Barraza Jose M, Vázquez-Gregorio Rafael, Lee Angel, Nathal Edgar
OBJECT: The use of intraoperative fluorescence has proven to be a useful tool in multiple neurosurgical procedures with a potential utility in treating arteriovenous malformations (AVMs). The aim of this study was to characterize dynamic changes of an AVM using a microscope-integrated technique at the moment of performing an intraoperative Sodium fluorescein videoangiography (FL-VAG) at each of the resection phases. METHODS: Our study at the National Institute of Neurology and Neurosurgery-Mexico City, prospectively recruited twelve patients harboring an AVM, using FL-VAG as an ancillary technique for the resection of the lesion...
June 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29901381/ttv-what-is-and-what-we-know-in-mexico
#2
Marco Antonio Torres-Castro, Aarón Beltrán Yeh-Gorocica, Fernando Isaías Puerto-Manzano
The aim of this editorial is to present a brief description of the Torque teno virus’ epidemiology and establish the actuality of their study in México. Also, we mentioned the studies made in México and Yucatán, specifically in the Center of Regional Research “Dr. Hideyo Noguchi” of the Autonomous University of Yucatán.
March 2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29852092/high-frequency-resistance-training-does-not-promote-greater-muscular-adaptations-compared-to-low-frequencies-in-young-untrained-men
#3
Cintia Barcelos, Felipe Damas, Sanmy Rocha Nóbrega, Carlos Ugrinowitsch, Manoel Emílio Lixandrão, Lucas Marcelino Eder Dos Santos, Cleiton Augusto Libardi
The aim of the study was to compare the effect of resistance training (RT) frequencies of five times (RT5), thrice- (RT3) or twice- (RT2) weekly in muscle strength and hypertrophy in young men. Were used a within-subjects design in which 20 participants had one leg randomly assigned to RT5 and the other to RT3 or to RT2. 1 RM and muscle cross-sectional area (CSA) were assessed at baseline, after four (W4) and eight (W8) RT weeks. RT5 resulted in greater total training volume (TTV) than RT3 and RT2 (P = ...
May 31, 2018: European Journal of Sport Science
https://www.readbyqxmd.com/read/29843750/torque-teno-virus-dynamics-during-the-first-year-of-life
#4
Elena A Tyschik, Anastasiya S Rasskazova, Anna V Degtyareva, Denis V Rebrikov, Gennady T Sukhikh
BACKGROUND: Torque teno virus is a small chronically persisting circular negative ssDNA virus reaching near 100% prevalence. It is reported to be a marker for immune function in immunocompromised patients. The possibility of vertical maternal-fetal transmission remains controversial but incidence rate of TTV DNA in children increased with age. TTV dynamics well studied for allogeneic hematopoietic stem cell transplantation as a predictor of post-transplant complications but there is no viral proliferation kinetics data for other patient groups or healthy individuals...
May 30, 2018: Virology Journal
https://www.readbyqxmd.com/read/29784463/anti-m%C3%A3-llerian-hormone-profiling-in-prepubertal-horses-and-its-relationship-with-gonadal-function
#5
Dragos Scarlet, Manuela Wulf, Juliane Kuhl, Martin Köhne, Natascha Ille, Alan J Conley, Christine Aurich
Anti-Müllerian hormone (AMH) has gained increasing interest as a biomarker for assessment of gonadal activity. The ability to predict the ovarian follicular reserve of prepubertal female horses (fillies) or to identify stallions with testicular pathologies already during their prepubertal life has not been analyzed so far. Both would help to select fertile horses and reduce costs associated with keeping animals. The objectives of the present study were to (1) assess AMH, LH, FSH, progesterone (females) and testosterone (males) dynamics in prepubertal horses from birth onwards and (2) determine whether AMH concentrations detected in plasma of prepubertal female and male horses are correlated with postpubertal gonadal development...
May 15, 2018: Theriogenology
https://www.readbyqxmd.com/read/29747074/high-dose-zinc-oral-supplementation-after-stem-cell-transplantation-causes-an-increase-of-trecs-and-cd4-na%C3%A3-ve-lymphocytes-and-prevents-ttv-reactivation
#6
Lorenzo Iovino, Francesco Mazziotta, Giovanni Carulli, Francesca Guerrini, Riccardo Morganti, Valentina Mazzotti, Fabrizio Maggi, Lisa Macera, Enrico Orciuolo, Gabriele Buda, Edoardo Benedetti, Francesco Caracciolo, Sara Galimberti, Mauro Pistello, Mario Petrini
INTRODUCTION: Zinc plays an important role in thymic function and immune homeostasis. We performed a prospective clinical trial using a high-dose zinc oral supplementation to improve the immune reconstitution after hematopoietic stem cell transplant (HSCT). PATIENTS AND METHODS: We enrolled 18 patients undergoing autologous HSCT for multiple myeloma. Nine patients were randomized to receive only a standard antimicrobial prophylaxis; whereas, nine patients received in addition 150 mg/day of zinc from day +5 to day +100 after transplant...
May 2, 2018: Leukemia Research
https://www.readbyqxmd.com/read/29727487/kinetics-of-torque-teno-virus-dna-load-in-saliva-and-plasma-following-allogeneic-hematopoietic-stem-cell-transplantation
#7
Eliseo Albert, Ignacio Torres, Alberto Talaya, Estela Giménez, José Luis Piñana, Juan Carlos Hernández-Boluda, Daniele Focosi, Lisa Macera, Fabrizio Maggi, Carlos Solano, David Navarro
Plasma Torque Teno virus (TTV) DNA load directly correlates with the degree of T-cell immune reconstitution early after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Here, the kinetics of oral TTV DNA shedding was examined to assess whether quantitation of TTV DNA load in saliva may either replace or complement that in plasma for predicting lymphocyte (ALC) reconstitution following engraftment. This prospective observational study enrolled 38 non-consecutive allo-HSCT recipients. Saliva and plasma specimens were collected at baseline (pre-transplant) and at around days +30, +50 and +90 after allo-HSCT...
May 4, 2018: Journal of Medical Virology
https://www.readbyqxmd.com/read/29644247/quantification-of-torque-teno-virus-and-epstein-barr-virus-is-of-limited-value-for-predicting-the-net-state-of-immunosuppression-after-lung-transplantation
#8
Rickard Nordén, Jesper Magnusson, Anna Lundin, Ka-Wei Tang, Staffan Nilsson, Magnus Lindh, Lars-Magnus Andersson, Gerdt C Riise, Johan Westin
Background: Major hurdles for survival after lung transplantation are rejections and infectious complications. Adequate methods for monitoring immune suppression status are lacking. Here, we evaluated quantification of torque teno virus (TTV) and Epstein-Barr virus (EBV) as biomarkers for defining the net state of immunosuppression in lung-transplanted patients. Methods: This prospective single-center study included 98 patients followed for 2 years after transplantation...
April 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29587272/development-of-an-immunoassay-for-detection-of-torque-teno-virus-ttv-antibodies-using-the-n22-expression-product-from-ttv-genotype-2
#9
Dhananjay Singh Mankotia, Mohammad Irshad
AIMS: This study describes an immunoassay to detect anti-torque teno virus (TTV) antibodies using a peptide obtained from expression of the N22 region of TTV genotype 2. METHODS: The N22 region (∼500 bp) of TTV genotype 2 was cloned in a pET-28a(+) vector and expressed in ZYM-5052 autoinduction medium. Following metal affinity chromatography, a purified polypeptide was used as an antigen for the development of an immunoassay to detect anti-TTV antibodies in human sera...
2017: Intervirology
https://www.readbyqxmd.com/read/29568043/first-detection-of-human-hepegivirus-1-hhpgv-1-in-iranian-patients-with-hemophilia
#10
Yazdan Bijvand, Mohammad Reza Aghasadeghi, Fatemeh Sakhaee, Parviz Pakzad, Farzam Vaziri, Alireza Azizi Saraji, Fatemeh Rahimi Jamnani, Seyed Davar Siadat, Abolfazl Fateh
A novel blood-borne virus called the human hepegivirus 1 (HHpgV-1) was recently discovered in hemophilia patients. The present study aimed to investigate the presence of HHpgV-1 in hemophilia patients. A total of 436 serum samples were investigated for the presence of hepatitis C virus (HCV), human pegivirus-1 (HPgV-1), torque teno virus (TTV), and HHpgV-1. Out of the 436 patients, 163 (37.4%), 19 (4.4%), 76 (17.4%), and four (0.9%) patients were positive for HCV, HPgV-1, TTV, and HHpgV-1, respectively. HHpgV-1 patients had a mean viral load of 4...
March 22, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29551863/detection-of-cytomegalovirus-epstein-barr-virus-and-torque-teno-virus-in-subgingival-and-atheromatous-plaques-of-cardiac-patients-with-chronic-periodontitis
#11
Sriraman Priyanka, Gurumoorthy Kaarthikeyan, Jayakumar Doraiswamy Nadathur, Anbarasu Mohanraj, Avinash Kavarthapu
Background: Periodontitis and atherosclerosis represent a chronic inflammatory process. The incidence of periodontitis in cardiac patients with atherosclerosis is a well-established fact. The role of viruses in the etiopathogenesis of both has been proposed. Aim: The aim of the study was to evaluate the prevalence of Torque Teno virus (TTV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV) in cardiac patients with atherosclerosis and coexisting chronic periodontitis (CP)...
November 2017: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29548656/clinical-significance-of-changes-in-torque-teno-virus-dna-titer-after-chemotherapy-in-patients-with-primary-lung-cancer
#12
Tetsuro Sawata, Masashi Bando, Masayuki Nakayama, Naoko Mato, Hideaki Yamasawa, Masaharu Takahashi, Hiroaki Okamoto, Yukihiko Sugiyama
BACKGROUND: Several studies have reported that viral infections are related to lung cancer. We previously reported the involvement of Torque teno virus (TTV) in patients with lung cancer and idiopathic pulmonary fibrosis. However, the role of TTV in lung cancer growth, and its influence on changes in TTV DNA titers due to idiopathic pulmonary fibrosis (IPF) in lung cancer patients are poorly understood. METHODS: Serum TTV DNA titers were measured in serum samples obtained from patients with lung cancer...
March 2018: Respiratory Investigation
https://www.readbyqxmd.com/read/29536496/relevant-tumor-sink-effect-in-prostate-cancer-patients-receiving-177lu-psma-617-radioligand-therapy
#13
Christian Filss, Alexander Heinzel, Berthold Miiller, Andreas T J Vogg, Karl-Josef Langen, Felix M Mottaghy
AIM: In metastatic prostate cancer patients PSMA targeting radioligands have gained significant impact as theranostic probes. In this study a correlation between total tumor volume (TTV) and measured kidney dose as well as salivary glands (SG) uptake in 177 Lu-PSMA-617 therapy was evaluated. METHODS: Eleven consecutive prostate cancer patients receiving a first cylcle of 177 Lu-PSMA-617 (administered activity of approximately 6GBq) were included. The 68 Ga-PSMA-11 PET/CT scan previous to therapy was used to determine TTV and SG uptake (glandulae submandibularis) employing PMOD version 3...
February 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29452573/the-effect-of-metformin-treatment-in-obese-insulin-resistant-patients-with-euthyroid-goiter
#14
Nicoleta Răcătăianu, Sorana Daniela Bolboacă, Adela-Viviana Sitar-Tăut, Smaranda Mârza, Daniela Moga, Ana Valea, Cristina Ghervan
Objective The study's objective was to evaluate the thyroid parameters in obese insulin-resistant patients with euthyroid diffuse or nodular goiter, following Metformin treatment. Patients and methods The study was experimental, open, and prospective. Fifty-three patients aged 18-68 were enrolled for two years. Obese insulin-resistant patients (cut-off Homeostasis-Model-Assessment of Insulin Resistance-HOMA-IR ≥ 2.5) with euthyroid nodular/diffuse goiter were included. Subjects with diabetes, hypo-/hyper-thyroidism, autoimmune thyroiditis, psychiatric disorders, liver or heart failure were excluded...
February 16, 2018: Acta Clinica Belgica
https://www.readbyqxmd.com/read/29447223/virome-and-bacteriome-characterization-of-children-with-pneumonia-and-asthma-in-mexico-city-during-winter-seasons-2014-and-2015
#15
Jose A Romero-Espinoza, Yazmin Moreno-Valencia, Rodrigo H Coronel-Tellez, Manuel Castillejos-Lopez, Andres Hernandez, Aaron Dominguez, Angel Miliar-Garcia, Arturo Barbachano-Guerrero, Rogelio Perez-Padilla, Alejandro Alejandre-Garcia, Joel A Vazquez-Perez
BACKGROUND: Acute asthma exacerbations and pneumonia are important causes of morbidity and mortality in children and may coexist in the same children, although symptom overlap may lead to difficulties in diagnosis. Microbial and viral diversity and differential abundance of either may play an important role in infection susceptibility and the development of acute and chronic respiratory diseases. OBJECTIVES: To describe the virome and bacteriome present in the upper respiratory tract of hospitalized children with a clinical diagnosis of asthma and pneumonia during an acute exacerbation and an acute respiratory illness ARI episode respectively...
2018: PloS One
https://www.readbyqxmd.com/read/29419479/the-effect-of-total-tumor-volume-on-the-biologically-effective-dose-of-tumor-and-kidneys-for-177-lu-labelled-psma-peptides
#16
Nusrat Begum, Anne Thieme, Nina Eberhardt, Robert Tauber, Ambros J Beer, Gerhard Glatting, Matthias Eiber, Peter Kletting
Aim: To simulate the effect of PSMA positive total tumor volume (TTV) on the tumor and organs at risk (OARs) biologically effective doses (BEDs) in patients with metastatic castration resistant prostate cancer (mCRPC) in 177 Lu-PSMA radioligand therapy. Methods: A physiologically-based pharmacokinetic model was fitted to data of 13 patients treated with 177 Lu-PSMA I&T. The tumor, kidneys and salivary glands BEDs were simulated for TTVs of 0.1-10 l. The activity and peptide amounts leading to an optimal tumor-to-kidneys BED ratio were also investigated...
February 1, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29407376/detection-and-phylogenetic-analysis-of-torque-teno-virus-ttv-carried-by-murine-rodents-and-house-shrews-in-china
#17
Yi-Quan Xiong, Yun Mo, Ming-Ji Chen, Wei Cai, Wen-Qiao He, Qing Chen
Between May 2015 and May 2017, 496 animals (473 murine rodents and 23 house shrews) were captured in six regions of China. A total of 22.8% (113/496) of throat swabs, 29.1% (142/488) of fecal samples and 23.8% (54/227) of serum samples tested positive for rodent torque teno virus 3 (RoTTV3). The positive rate in Rattus norvegicus was higher than the rate in Rattus tanezumi and Rattus losea. Of 23 house shrews, one throat swab and one serum sample were positive for RoTTV3. Ten murine rodents were simultaneously positive for RoTTV3 in throat swab, fecal and serum samples...
March 2018: Virology
https://www.readbyqxmd.com/read/29346782/a-fair-chance-for-everyone-total-tumor-volume-as-a-selection-tool-in-liver-transplantation-for-hepatocellular-carcinoma
#18
Hugo Pinto-Marques, Silvia Silva, Mafalda Sobral, Rui Perdigoto, Américo Martins, Eduardo Barroso
Total tumor volume (TTV) has been proposed as a more accurate means of selecting patients for liver transplantation (LT) due to hepatocellular carcinoma (HCC). We aim to analyze the role of TTV in a population with a short waiting time on list. METHODS: Analysis of a prospective database of patients submitted to LT for HCC between September 1992 and February 2014. TTV, Milan criteria (MC), UCSF (University of California San Francisco), and "Up to Seven" criteria were calculated both with preoperative imaging exams and histological data...
January 18, 2018: Digestive Surgery
https://www.readbyqxmd.com/read/29311716/discovering-viral-genomes-in-human-metagenomic-data-by-predicting-unknown-protein-families
#19
Mauricio Barrientos-Somarribas, David N Messina, Christian Pou, Fredrik Lysholm, Annelie Bjerkner, Tobias Allander, Björn Andersson, Erik L L Sonnhammer
Massive amounts of metagenomics data are currently being produced, and in all such projects a sizeable fraction of the resulting data shows no or little homology to known sequences. It is likely that this fraction contains novel viruses, but identification is challenging since they frequently lack homology to known viruses. To overcome this problem, we developed a strategy to detect ORFan protein families in shotgun metagenomics data, using similarity-based clustering and a set of filters to extract bona fide protein families...
January 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29282765/relationships-between-total-testicular-volume-reproductive-parameters-and-surrogate-measures-of-adiposity-in-men-presenting-for-couple-s-infertility
#20
K Ehala-Aleksejev, M Punab
The objective of this study was to investigate the relationships between total testicular volume (TTV), reproductive parameters and adiposity measures: body mass index, waist circumference and waist-to-height ratio. Semen analysis was performed, and reproductive hormone levels were measured in 2,672 male patients (mean age 32.6) due to couple's infertility. Significant, positive correlations between semen parameters and the TTV were found. Gonadotrophins were negatively related to the TTV, and testosterone was not related to the TTV...
December 28, 2017: Andrologia
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