keyword
MENU ▼
Read by QxMD icon Read
search

lung perfusion spect

keyword
https://www.readbyqxmd.com/read/28430738/three-dimensional-fractal-analysis-of-99mtc-maa-spect-images-in-chronic-thromboembolic-pulmonary-hypertension-for-evaluation-of-response-to-balloon-pulmonary-angioplasty-association-with-pulmonary-arterial-pressure
#1
Yasuhiro Maruoka, Michinobu Nagao, Shingo Baba, Takuro Isoda, Yoshiyuki Kitamura, Yuzo Yamazaki, Koichiro Abe, Masayuki Sasaki, Kohtaro Abe, Hiroshi Honda
OBJECTIVE: Balloon pulmonary angioplasty (BPA) is used for inoperable chronic thromboembolic pulmonary hypertension (CTEPH), but its effect cannot be evaluated noninvasively. We devised a noninvasive quantitative index of response to BPA using three-dimensional fractal analysis (3D-FA) of technetium-99m-macroaggregated albumin (Tc-MAA) single-photon emission computed tomography (SPECT). PATIENTS AND METHODS: Forty CTEPH patients who underwent pulmonary perfusion scintigraphy and mean pulmonary arterial pressure (mPAP) measurement by right heart catheterization before and after BPA were studied...
April 20, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28408698/reproducibility-of-lobar-perfusion-and-ventilation-quantification-using-a-spect-ct-segmentation-software-in-lung-cancer-patients
#2
Karine Provost, Antoine Leblond, Annie Gauthier Lemire, Edith Fillion, Houda Bahig, Martin Lord
Planar perfusion scintigraphy with Tc99m-labelled macroaggregated albumin (Tc99m-MAA) is often used for pre-therapy quantification of regional lung perfusion in lung cancer patients, particularly in patients with poor respiratory function. However, subdividing lung parenchyma in rectangular regions of interests, as done on planar images, is a poor reflection of true lobar anatomy. New tridimensional methods using SPECT and SPECT/CT have been introduced, including a semi-automatic lung segmentation software (Hermes Medical Solutions)...
April 13, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28376242/lung-perfusion-mri-vs-spect-for-screening-in-suspected-chronic-thromboembolic-pulmonary-hypertension
#3
Christopher S Johns, Andrew J Swift, Smitha Rajaram, Paul J C Hughes, David J Capener, David G Kiely, James M Wild
PURPOSE: To assess the diagnostic accuracy of magnetic resonance imaging (MRI) perfusion against perfusion single photon emission tomography (SPECT) screening for chronic thromboembolic pulmonary hypertension (CTEPH). Ventilation/perfusion (V/Q) scintigraphy is recommended to screen for suspected CTEPH. It has previously been shown that 3D dynamic contrast-enhanced (DCE) lung perfusion MRI has a similar sensitivity for diagnosing CTEPH in comparison to planar perfusion scintigraphy; however, planar scintigraphy has now been largely replaced by SPECT, due to higher spatial resolution and sensitivity...
April 4, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28294159/to-find-a-better-dosimetric-parameter-in-the-predicting-of-radiation-induced-lung-toxicity-individually-ventilation-perfusion-or-ct-based
#4
Lin-Lin Xiao, Guoren Yang, Jinhu Chen, Xiaohui Wang, Qingwei Wu, Zongwei Huo, Qingxi Yu, Jinming Yu, Shuanghu Yuan
This study aimed to find a better dosimetric parameter in predicting of radiation-induced lung toxicity (RILT) in patients with non-small cell lung cancer (NSCLC) individually: ventilation(V), perfusion (Q) or computerized tomography (CT) based. V/Q single-photon emission computerized tomography (SPECT) was performed within 1 week prior to radiotherapy (RT). All V/Q imaging data was integrated into RT planning system, generating functional parameters based on V/Q SPECT. Fifty-seven NSCLC patients were enrolled in this prospective study...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28268559/automatic-segmentation-of-lungs-in-spect-images-using-active-shape-model-trained-by-meshes-delineated-in-ct-images
#5
Cheimariotis Grigorios-Aris, Al-Mashat Mariam, Haris Kostas, Aletras H Anthony, Jogi Jonas, Bajc Marika, Maglaveras Nicolaos, Heiberg Einar
This paper presents a fully automated method for segmentation of 3D SPECT ventilation and perfusion images. It relies on statistical information on lung shape derived by CT manual segmentation and its main processing steps are: shape model extraction, binary segmentation, positioning of mean shape in SPECT images and iterative shape adaptation based on intensity profiles and on what is considered `plausible' lung shape. The Active Shape Model is used to generate accurate anatomic results in SPECT images with functional information and thus unclear borders, especially in the case of pathologies...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28255667/framework-for-radiation-pneumonitis-risk-stratification-based-on-anatomic-and-perfused-lung-dosimetry
#6
Gurleen Dhami, Jing Zeng, Hubert J Vesselle, Paul E Kinahan, Robert S Miyaoka, Shilpen A Patel, Ramesh Rengan, Stephen R Bowen
PURPOSE: To design and apply a framework for predicting symptomatic radiation pneumonitis in patients undergoing thoracic radiation, using both pretreatment anatomic and perfused lung dose-volume parameters. MATERIALS AND METHODS: Radiation treatment planning CT scans were coregistered with pretreatment [(99m)Tc]MAA perfusion SPECT/CT scans of 20 patients who underwent definitive thoracic radiation. Clinical radiation pneumonitis was defined as grade ≥ 2 (CTCAE v4 grading system)...
March 2, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28236024/molecular-imaging-of-the-human-pulmonary-vascular-endothelium-in-pulmonary-hypertension-a-phase-ii-safety-and-proof-of-principle-trial
#7
François Harel, David Langleben, Steve Provencher, Alain Fournier, Vincent Finnerty, Quang T Nguyen, Myriam Letourneau, Xavier Levac, Gad Abikhzer, Jean Guimond, Asmaa Mansour, Marie-Claude Guertin, Jocelyn Dupuis
PURPOSE: The adrenomedullin receptor is densely expressed in the pulmonary vascular endothelium. PulmoBind, an adrenomedullin receptor ligand, was developed for molecular diagnosis of pulmonary vascular disease. We evaluated the safety of PulmoBind SPECT imaging and its capacity to detect pulmonary vascular disease associated with pulmonary hypertension (PH) in a human phase II study. METHODS: Thirty patients with pulmonary arterial hypertension (PAH, n = 23) or chronic thromboembolic PH (CTEPH, n = 7) in WHO functional class II (n = 26) or III (n = 4) were compared to 15 healthy controls...
February 24, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28226736/automatic-segmentation-of-lungs-in-spect-images-using-active-shape-model-trained-by-meshes-delineated-in-ct-images
#8
Cheimariotis Grigorios-Aris, Al-Mashat Mariam, Haris Kostas, Aletras H Anthony, Jogi Jonas, Bajc Marika, Maglaveras Nicolaos, Heiberg Einar, Cheimariotis Grigorios-Aris, Al-Mashat Mariam, Haris Kostas, Aletras H Anthony, Jogi Jonas, Bajc Marika, Maglaveras Nicolaos, Heiberg Einar, Bajc Marika, Al-Mashat Mariam, Jogi Jonas, Heiberg Einar, Haris Kostas, Maglaveras Nicolaos, Aletras H Anthony, Cheimariotis Grigorios-Aris
This paper presents a fully automated method for segmentation of 3D SPECT ventilation and perfusion images. It relies on statistical information on lung shape derived by CT manual segmentation and its main processing steps are: shape model extraction, binary segmentation, positioning of mean shape in SPECT images and iterative shape adaptation based on intensity profiles and on what is considered `plausible' lung shape. The Active Shape Model is used to generate accurate anatomic results in SPECT images with functional information and thus unclear borders, especially in the case of pathologies...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28197219/factors-determining-altered-perfusion-after-acute-pulmonary-embolism-assessed-by-quantified-single-photon-emission-computed-tomography-perfusion-scan
#9
Marc Meysman, Hendrik Everaert, Walter Vincken
AIM OF THE STUDY: The aim of the study was to analyze the evolution of perfusion (Q)-defects in patients treated for acute pulmonary embolism (PE), correlation with baseline parameters and evaluation of recurrence risk. METHODS: This is a single-center prospective observational cohort study in symptomatic normotensive PE. Comparison of the ventilation/perfusion single-photon emission computed tomography (V/Q-SPECT) acquired at baseline with a quantified SPECT (Q-SPECT) repeated at 1 week and 6 months...
January 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/28048288/su-d-202-01-functional-lung-avoidance-and-response-adaptive-escalation-flare-rt-feasibility-of-a-precision-radiation-oncology-strategy
#10
S Bowen, E Lee, R Miyaoka, J Saini, P Kinahan, G Sandison, T Wong, H Vesselle, R Rengan, J Zeng
PURPOSE: NSCLC patient RT is planned without consideration of spatial heterogeneity in lung function or tumor response, which may have contributed to failed uniform dose escalation in a randomized trial. The feasibility of functional lung avoidance and response-adaptive escalation (FLARE) RT to reduce dose to [(9 9m) Tc]MAA-SPECT/CT perfused lung while redistributing 74Gy within [(1 8) F]FDG-PET/CT biological target volumes was assessed. METHODS: Eight Stage IIB-IIIB NSCLC patients underwent FDG-PET/CT and MAA-SPECT/CT treatment planning scans...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27986344/decreased-lung-perfusion-after-breast-chest-wall-irradiation-quantitative-results-from-a-prospective-clinical-trial
#11
Adam L Liss, Robin B Marsh, Nirav S Kapadia, Daniel L McShan, Virginia E Rogers, James M Balter, Jean M Moran, Kristy K Brock, Matt J Schipper, Reshma Jagsi, Kent A Griffith, Kevin R Flaherty, Kirk A Frey, Lori J Pierce
PURPOSE: To quantify lung perfusion changes after breast/chest wall radiation therapy (RT) using pre- and post-RT single photon emission computed tomography/computed tomography (SPECT/CT) attenuation-corrected perfusion scans; and correlate decreased perfusion with adjuvant RT dose for breast cancer in a prospective clinical trial. METHODS AND MATERIALS: As part of an institutional review board-approved trial studying the impact of RT technique on lung function in node-positive breast cancer, patients received breast/chest wall and regional nodal irradiation including superior internal mammary node RT to 50 to 52...
February 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27648373/the-benefit-of-personalized-hybrid-spect-ct-pulmonary-imaging
#12
Milan Simanek, Pavel Koranda
Hybrid pulmonary imaging in the present day has seen a fusion of various uses of CT scans, including angiography (CTAG), diagnostic CT, low dose CT (LDCT), and perfusion or ventilation scintigraphy in tomographic or planar imaging. Determining the most effective individualized test for the complete diagnostics of patients with pulmonary symptoms for various groups of patients is a major issue. The aim of the present study was to assess the effectiveness of the implementation of hybrid imaging in current methods of nuclear medicine in differential diagnostics of pulmonary embolism (PE)...
2016: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27637724/functional-image-guided-radiotherapy-planning-for-normal-lung-avoidance
#13
R H Ireland, B A Tahir, J M Wild, C E Lee, M Q Hatton
For patients with lung cancer undergoing curative intent radiotherapy, functional lung imaging can be incorporated into treatment planning to modify the dose distribution within non-target volume lung by differentiation of lung regions that are functionally defective or viable. This concept of functional image-guided lung avoidance treatment planning has been investigated with several imaging modalities, primarily single photon emission computed tomography (SPECT), but also hyperpolarised gas magnetic resonance (MR) imaging, positron emission tomography (PET) and computed tomography (CT)-based measures of lung biomechanics...
November 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27620309/radionuclide-diagnosis-of-pulmonary-embolism
#14
Søren Hess, Poul Henning Madsen
Diagnostic imaging plays an integral role in the diagnostic workup of suspected pulmonary embolism, and several modalities have been employed over the years. In recent years, the choice has been narrowed to either computer tomographic or radionuclide based methods, i.e. computer tomographic angiography (CTA) and ventilation-perfusion scintigraphy (V/Q-scan). Both methods display advantages and shortcomings, and while we provide some insights into CTA and alternative methods, the paper's main focus is a review of the V/Q-scan...
September 13, 2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27553468/-68-ga-pet-ventilation-and-perfusion-lung-imaging-current-status-and-future-challenges
#15
REVIEW
Dale L Bailey, Enid M Eslick, Geoffrey P Schembri, Paul J Roach
Gallium-68 ((68)Ga) is a positron-emitting radionuclide suitable for positron emission tomography (PET) imaging that has a number of convenient features-it has a physical half life of 68 minutes, it is generator produced at the PET facility and needs no local cyclotron, and being a radiometal is able to be chelated to a number of useful molecules for diagnostic imaging with PET. (68)Ga has recently been investigated as a radiotracer for ventilation and perfusion (V/Q) lung imaging. It is relatively easy to produce both V/Q radiopharmaceuticals labeled with (68)Ga for PET studies, it offers higher spatial resolution than equivalent SPECT studies, the short half life allows for multiple (repeated) scans on the same day, and low amounts of radiotracer can be used thus limiting the radiation dose to the subject...
September 2016: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/27540433/vertebral-uptake-of-tc-99m-macroaggregated-albumin-maa-with-spect-ct-occurring-in-superior-vena-cava-obstruction
#16
Shawn Karls, Hani Hassoun, Vilma Derbekyan
A 67-year-old male presented with dyspnea for which lung scintigraphy was ordered to rule out pulmonary embolus. Planar images demonstrated abnormal midline uptake of Tc-99m macroaggregated albumin, which SPECT/CT localized to several thoracic vertebrae. Thoracic vertebral uptake on perfusion lung scintigraphy was previously described on planar imaging. Radionuclide venography and contrast-enhanced CT subsequently demonstrated superior vena cava (SVC) obstruction with collateralization through the azygous/hemiazygous system and vertebral venous plexus...
September 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27523813/contrast-enhanced-ct-and-mri-based-perfusion-assessment-for-pulmonary-diseases-basics-and-clinical-applications
#17
Yoshiharu Ohno, Hisanobu Koyama, Ho Yun Lee, Sachiko Miura, Takeshi Yoshikawa, Kazuro Sugimura
Assessment of regional pulmonary perfusion as well as nodule and tumor perfusions in various pulmonary diseases are currently performed by means of nuclear medicine studies requiring radioactive macroaggregates, dual-energy computed tomography (CT), and dynamic first-pass contrast-enhanced perfusion CT techniques and unenhanced and dynamic first-pass contrast enhanced perfusion magnetic resonance imaging (MRI), as well as time-resolved three-dimensional or four-dimensional contrast-enhanced magnetic resonance angiography (MRA)...
September 2016: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/27461384/spect-ct-vq-versus-ctpa-for-diagnosing-pulmonary-embolus-and-other-lung-pathology-pre-existing-lung-disease-should-not-be-a-contraindication
#18
Kartik Dev Bhatia, Chaitanya Ambati, Rajiv Dhaliwal, Royce Paschkewitz, Eugene Hsu, Bao Ho, Andy Young, Louise Emmett
INTRODUCTION: Single Photon Emission Computed Tomography-Ventilation-Perfusion (SPECT-VQ) with low-dose CT (SPECT-CT/VQ) has equivalent diagnostic accuracy to CTPA for diagnosing pulmonary embolus (PE) while using lower radiation doses, but is underutilized owing to perceived inaccuracy of scintigraphy in the setting of pre-existing lung disease. This study assesses the accuracy of SPECT-CT/VQ compared with CTPA for the diagnosis of PE, including in patients with pre-existing lung disease...
August 2016: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/27368528/systemic-and-regional-pulmonary-function-after-segmentectomy
#19
Hiroaki Nomori, Yue Cong, Hiroshi Sugimura
OBJECTIVE: Segmentectomy includes numerous kinds of procedures that may result in decreased postoperative pulmonary function. This causes controversy regarding the functional advantage of segmentectomy over lobectomy. To clarify the difference between the procedures, systemic and regional pulmonary functions of the resected segments must be examined. METHODS: Pulmonary function tests and lung perfusion single-photon emission computed tomography (SPECT) were prospectively conducted before and after segmentectomy in 117 patients who were divided into groups based on resection of <2 segments (n = 83), ≥2 segments (n = 20), and left upper division (LUD) (n = 14)...
September 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27295657/fully-automated-data-driven-respiratory-signal-extraction-from-spect-images-using-laplacian-eigenmaps
#20
James C Sanders, Philipp Ritt, Torsten Kuwert, A Hans Vija, Andreas K Maier
We propose a data-driven method for extracting a respiratory surrogate signal from SPECT list-mode data. The approach is based on dimensionality reduction with Laplacian Eigenmaps. By setting a scale parameter adaptively and adding a series of post-processing steps to correct polarity and normalization between projections, we enable fully-automatic operation and deliver a respiratory surrogate signal for the entire SPECT acquisition. We validated the method using 67 patient scans from three acquisition types (myocardial perfusion, liver shunt diagnostic, lung inhalation/perfusion) and an Anzai pressure belt as a gold standard...
June 7, 2016: IEEE Transactions on Medical Imaging
keyword
keyword
87465
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"