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S Mailfert, Y Hamon, N Bertaux, H-T He, D Marguet
Due to the intrinsic molecular Brownian agitation within plasma membrane and the vast diversity of membrane components, it is expected that the plasma membrane organization is highly heterogeneous with the formation of local complex multicomponent assemblies of lipids and proteins on different time scales. Still, deciphering this lateral organization on living cells and on the appropriate length and temporal scales has been challenging but is crucial to advance our knowledge on the biological function of the plasma membrane...
2017: Methods in Cell Biology
Jürgen Popp
No abstract text is available yet for this article.
January 2017: Journal of Biophotonics
Shou-Fei Gao, Ying-Ying Wang, Xiao-Lu Liu, Chang Hong, Shuai Gu, Pu Wang
We report on a hollow-core fiber (HCF) whose fundamental transmission band covers almost the whole visible spectral window, starting at 440 nm. This HCF, in the form of a nodeless structure (NL-HCF), exhibits unprecedented optical performance in terms of low transmission attenuation of 80 dB/km at 532 nm, a broad transmission bandwidth from 440 to 1200 nm, a low bending loss of 0.2 dB/m at 532 nm under 8 cm bending radius, and single-mode profile. When launched to high-power picosecond laser systems at 532 nm, the fiber, exposed to ambient air, could easily deliver an 80 ps, 58 MHz, 32 W average power laser pulse with no damage and a 20 ps, 1 kHz high-energy laser pulse with a damage threshold in excess of 144 μJ at a fiber output...
January 1, 2017: Optics Letters
J Siewerdsen, R Jeraj
The Expanding Horizons travel grant program provides opportunity for students and trainees to broaden the scope of scientific meetings they attend and gain insight from research outside traditional domains of medical physics. Through participation in such conferences, early-career researchers are introduced to new topics with relevance to medical physics research as a means to expand the scientific horizons of our discipline. This year, 21 Expanding Horizons travel grants were awarded, granting travel to 17 conferences, including: Radiomics, the World Molecular Imaging Society (WMIS), the 3D Printing Conference and Expo, the GPU Technology Conference, the SIAM Imaging Science Conference, the Human Brain Mapping Conference, the OSA Conference on Clinical and Translational Biophotonics, the Society for Neuroscience, the AACR Conference on Tumor Microenvironment, and the Conference on Knowledge Discovery and Data Mining...
June 2016: Medical Physics
Govindaraj Dev Kumar, Robert C Williams, Hamzeh M Al Qublan, Nammalwar Sriranganathan, Renee R Boyer, Joseph D Eifert
The presence of dust is ubiquitous in the produce growing environment and its deposition on edible crops could occur. The potential of wind-distributed soil particulate to serve as a vehicle for S. Newport transfer to tomato blossoms and consequently, to fruits, was explored. Blossoms were challenged with previously autoclaved soil containing S. Newport (9.39log CFU/g) by brushing and airborne transfer. One hundred percent of blossoms brushed with S. Newport-contaminated soil tested positive for presence of the pathogen one week after contact (P<0...
February 21, 2017: International Journal of Food Microbiology
Gabriela Apiou-Sbirlea, Conor L Evans, Kristen M Kelly, Bruce J Tromberg
No abstract text is available yet for this article.
December 1, 2016: Journal of Biomedical Optics
Huijuan Li, Tengfei Wu, Jietao Liu, Changmei Gong, Xiaopeng Shao
We analyze the imaging of gray-scale objects through highly scattering layers. The theoretical investigation with numerical simulations shows that the contrast of the speckle autocorrelations varies regularly with the change of the gray scale of the object. Therefore, gray information is well contained in the autocorrelations of the speckle patterns, and gray-scale objects are able to be exacted from these autocorrelations via speckle correlation technology. Combined with phase retrieval via the generalized approximate message passing algorithm, recovery of the objects is realized and accurate gray-scale reconstruction is demonstrated via numerical simulations...
December 1, 2016: Applied Optics
Christoph Krafft
This contribution covers recent original research papers in the biophotonics field. The content is organized into main techniques such as multiphoton microscopy, Raman spectroscopy, infrared spectroscopy, optical coherence tomography and photoacoustic tomography, and their applications in the context of fluid, cell, tissue and skin diagnostics. Special attention is paid to vascular and blood flow diagnostics, photothermal and photodynamic therapy, tissue therapy, cell characterization, and biosensors for biomarker detection...
December 2016: Journal of Biophotonics
Sourabh Kumar, Kristine Boone, Jack Tuszyński, Paul Barclay, Christoph Simon
Given that many fundamental questions in neuroscience are still open, it seems pertinent to explore whether the brain might use other physical modalities than the ones that have been discovered so far. In particular it is well established that neurons can emit photons, which prompts the question whether these biophotons could serve as signals between neurons, in addition to the well-known electro-chemical signals. For such communication to be targeted, the photons would need to travel in waveguides. Here we show, based on detailed theoretical modeling, that myelinated axons could serve as photonic waveguides, taking into account realistic optical imperfections...
November 7, 2016: Scientific Reports
Wen-Kai Kuo, Jyun-Jheng Hsu, Chih-Kai Nien, Hsin Her Yu
In nature, in order to prevent attention from predators, the eyes of night-flying moths have evolutionarily developed an antireflective ability. The surfaces of their eyes are covered with a layer of a sub-wavelength structure that eliminates reflections of visible light. This layer allows the eyes of moths to escape detection in darkness, without reflections that could reveal the position of the moths to potential predators. In this study, we proposed a novel procedure for manufacturing a non-close-packed polystyrene (PS) nanosphere monolayer by combining the Langmuir-Blodgett (LB) deposition technique and oxygen plasma treatment...
November 23, 2016: ACS Applied Materials & Interfaces
Zilong Wu, Glen Kelp, Maruthi Nagavalli Yogeesh, Wei Li, Kyle M McNicholas, Andrew Briggs, Bharath Bangalore Rajeeva, Deji Akinwande, Seth R Bank, Gennady Shvets, Yuebing Zheng
There has been strong interest in developing multi-band plasmonic metasurfaces for multiple optical functions on single platforms. Herein, we developed Au moiré metasurface patches (AMMP), which leverage the tunable multi-band responses of Au moiré metasurfaces and the additional field enhancements of the metal-insulator-metal configuration to achieve dual-band plasmon resonance modes in near-infrared and mid-infrared regimes with high field enhancement. Furthermore, we demonstrate the multifunctional applications of AMMP, including surface-enhanced infrared spectroscopy, optical capture and patterning of bacteria, and photothermal denaturation of proteins...
October 25, 2016: Nanoscale
Pasquale Memmolo, Francesco Merola, Lisa Miccio, Martina Mugnano, Pietro Ferraro
No abstract text is available yet for this article.
December 1, 2016: Journal of Biomedical Optics
Bharath Bangalore Rajeeva, Derek S Hernandez, Mingsong Wang, Evan Perillo, Linhan Lin, Leonardo Scarabelli, Bharadwaj Pingali, Luis M Liz-Marzán, Andrew K Dunn, Jason B Shear, Yuebing Zheng
Selective localization of biomolecules at the hot spots of a plasmonic nanoparticle is an attractive strategy to exploit the light-matter interaction due to the high field concentration. Current approaches for hot spot targeting are time-consuming and involve prior knowledge of the hot spots. Multiphoton plasmonic lithography is employed to rapidly immobilize bovine serum albumin (BSA) hydrogel at the hot spot tips of a single gold nanotriangle (AuNT). Regioselectivity and quantity control by manipulating the polarization and intensity of the incident laser are also established...
November 2015: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
Francesco Saltarelli, Vikas Kumar, Daniele Viola, Francesco Crisafi, Fabrizio Preda, Giulio Cerullo, Dario Polli
Stimulated Raman scattering spectroscopy is a powerful technique for label-free molecular identification, but its broadband implementation is technically challenging. We introduce and experimentally demonstrate a novel approach based on photonic time stretch. The broadband femtosecond Stokes pulse, after interacting with the sample, is stretched by a telecom fiber to ≈15ns, mapping its spectrum in time. The signal is sampled through a fast analog-to-digital converter, providing single-shot spectra at 80-kHz rate...
September 19, 2016: Optics Express
Ben R Stading, Jorge E Osorio, Andres Velasco-Villa, Michael Smotherman, Brock Kingstad-Bakke, Tonie E Rocke
Bats (Order Chiroptera) are an abundant group of mammals with tremendous ecological value as insectivores and plant dispersers, but their role as reservoirs of zoonotic diseases has received more attention in the last decade. With the goal of managing disease in free-ranging bats, we tested modified vaccinia Ankara (MVA) and raccoon poxvirus (RCN) as potential vaccine vectors in the Brazilian Free-tailed bat (Tadarida brasiliensis), using biophotonic in vivo imaging and immunogenicity studies. Animals were administered recombinant poxviral vectors expressing the luciferase gene (MVA-luc, RCN-luc) through oronasal (ON) or intramuscular (IM) routes and subsequently monitored for bioluminescent signal indicative of viral infection...
October 17, 2016: Vaccine
Jiapei Dai, Zhuo Wang, Zehua Li, Fangyan Xiao
No abstract text is available yet for this article.
September 20, 2016: Proceedings of the National Academy of Sciences of the United States of America
Vincent Vuiblet, Michael Fere, Ezechiel Bankole, Alain Wynckel, Cyril Gobinet, Philippe Birembaut, Olivier Piot, Philippe Rieu
In brain-dead donor resuscitation, hydroxyethyl starch (HES) use has been associated with presence of osmotic-nephrosis-like lesions in kidney transplant recipients. Our aim was to determine whether the presence of HES in protocol renal graft biopsies at three months (M3) after transplantation is associated with renal graft quality. According to the HES administered to the donor during the procurement procedure, two groups of patients were defined according graft exposition to HES: HES group, (N = 20) and control group (N = 6)...
2016: Scientific Reports
Linhua Xu, Xuefeng Jiang, Guangming Zhao, Ding Ma, Hu Tao, Zhiwen Liu, Fiorenzo G Omenetto, Lan Yang
We have experimentally demonstrated an on-chip all-silk fibroin whispering gallery mode microresonator by using a simple molding and solution-casting technique. The quality factors of the fabricated silk protein microresonators are on the order of 10<sup>5</sup>. A high-sensitivity thermal sensor was realized in this silk fibroin microtoroid with a sensitivity of -1.17 nm/K, that is 8 times higher than previous WGM resonator-based thermal sensors. This opens the way to fabricate biodegradable and biocompatible protein based microresonators on a flexible chip for biophotonics applications...
September 5, 2016: Optics Express
Cleber Ferraresi, Nivaldo Antonio Parizotto, Marcelo Victor Pires de Sousa, Beatriz Kaippert, Ying-Ying Huang, Tomoharu Koiso, Vanderlei Salvador Bagnato, Michael R Hamblin
In the article by C. Ferraresi et al. (DOI:, published in J. Biophotonics 8, 740-754 (2015), a statement regarding the approval of some data the authors used is incorrect. This erratum is published to rectify this.
September 2016: Journal of Biophotonics
Christina Antoniou, Clio Dessinioti, Dimitrios Sotiriadis, Konstantinos Kalokasidis, George Kontochristopoulos, Athanasios Petridis, Dimitrios Rigopoulos, Denis Vezina, Andreas Nikolis
BACKGROUND: Although a variety of laser/light-based devices have been reported to be effective for the treatment of acne, long-term data on efficacy and safety in the management of moderate and severe inflammatory acne is lacking. The objective of this 12-week clinical trial was to evaluate the efficacy and safety of the KLOX BioPhotonic System, a LED blue light device using specific photo-converter chromophores, in the treatment of moderate to severe acne vulgaris. METHODS: One patient hemiface was randomly selected to receive 6 weeks of treatment (twice weekly) with the LED light and the photo-converter chromophores whereas the contralateral hemiface was not treated with the BioPhotonic System...
December 2016: International Journal of Dermatology
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