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https://www.readbyqxmd.com/read/28821204/absence-of-cmv-viremia-in-high-grade-glioma-patients-under-low-dosage-glucocorticoid-treatment
#1
Martina Schneider, Eva-Maria Reitter, Marie-Theres Kastner, Jakob Thannesberger, Franz J J Rieder, Matthias Preusser, Christine Marosi, Christoph Steininger
No abstract text is available yet for this article.
September 1, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/28821137/preparation-of-highly-oxidized-starch-using-hydrogen-peroxide-and-its-application-as-a-novel-ligand-for-zirconium-tanning-of-leather
#2
Yue Yu, Ya-Nan Wang, Wei Ding, Jianfei Zhou, Bi Shi
A series of highly-oxidized starch (HOS) were prepared using H2O2 and a copper-iron catalyst as a desired ligand for zirconium tanning of leather. The effects of catalyst and H2O2 dosages, and reaction temperature on the oxidation degree (OD, represented as the amount of carbonyl and carboxyl groups derived) of starch were investigated. The OD reached 76.2% when oxidation was conducted using 60% H2O2 and 0.015% catalyst at 98°C for 2h. (13)C NMR and FT-IR illustrated carbonyl and carboxyl groups were formed in HOS after oxidation...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821124/the-characterization-selenylation-and-antidiabetic-activity-of-mycelial-polysaccharides-from-catathelasma-ventricosum
#3
Yuntao Liu, Yuxian You, Yiwen Li, Lan Zhang, Leilei Yin, Yingbin Shen, Cheng Li, Hong Chen, Shujuan Chen, Bin Hu, Daiwen Chen
The mycelial polysaccharide from Catathelasma ventricosum (mCVP-1S) was found to be a heteropolysaccharide with an average size of 230kDa composed mainly of β-glucopyranosyl residues. The selenylation of mCVP-1S, performed using an HNO3-Na2SeO3 method, produced a series of selenized mCVP-1Ss (SemCVP-1Ss). Varying the reaction time, temperature and Na2SeO3 dosage altered the yield and selenium content of the SemCVP-1Ss. NMR spectra showed substitution mostly at C-6, and Congo red tests indicated excessive selenylation might destroy the triple-helical structure of SemCVP-1Ss...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821100/activation-of-tempo-by-clo2-for-oxidation-of-cellulose-by-hypochlorite-fundamental-and-practical-aspects-of-the-catalytic-system
#4
Timo Pääkkönen, Raili Pönni, Jinze Dou, Markus Nuopponen, Tapani Vuorinen
Bromide-free TEMPO-catalyzed oxidation of the primary alcohols by sodium hypochlorite (NaOCl) does not proceed without a prior activation of the catalyst. Here were demonstrate an immediate in situ activation of the catalyst with an equimolar addition of chlorine dioxide (ClO2) relative to TEMPO. Sodium bromide (NaBr) had a similar role in activating the catalyst although NaBr was needed in excess and the activation took several minutes depending on the dosage of NaBr. The activation method, or the concentration of NaBr, did not affect the bulk oxidation rate...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821078/fabrication-of-magnetic-particles-imprinted-cellulose-based-biocomposites-for-chromium-vi-removal
#5
Soodamani Periyasamy, Venkatrajan Gopalakannan, Natrayasamy Viswanathan
The present study was focused on Cr(VI) removal using eco-friendly materials like cellulose (Cel), hydrotalcite (HT), hydroxyapatite (HAp) and their composite forms. The cellulose/hydrotalcite (CelHT) and cellulose/hydroxyapatite (CelHAp) composites were synthesized by dispersing HT and HAp individually in cellulose polymeric matrix. To enhance the Cr(VI) sorption capacity (SC) and easy separation, cellulose supported magnetic composites namely iron-oxide coated cellulose/hydrotalcite (Fe3O4@CelHT) and cellulose/hydroxyapatite (Fe3O4@CelHAp) were synthesized by in situ fabrication method...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821050/clean-approach-to-synthesis-of-graphene-like-cufe2o4-polysaccharide-resin-nanohybrid-bifunctional-compound-for-dye-adsorption-and-bacterial-capturing
#6
Mostafa Hossein Beyki, Sarina Ehteshamzadeh Ganjbakhsh, Sara Minaeian, Farzaneh Shemirani
Focus of this research is on employment of a green route to prepare magnetic CuFe2O4@polysaccharide resin for environmental remediation purpose. The method is including solvent free solid state synthesis of copper ferrite nanoparticles by combustion route using cellulose as fuel. Then polysaccharide resin as well as its magnetic composite was prepared by using glucose, citric acid and copper ferrite as solid raw materials. Characterization study using FESEM and TEM images showed that as synthesized resin possesses graphene like structure as ferrite nanoparticles are dispersed in the matrice of resin...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821027/preparation-characterization-and-antibacterial-activity-of-oxidized-%C3%AE%C2%BA-carrageenan
#7
Mingjin Zhu, Liming Ge, Yongbo Lyu, Yaxin Zi, Xinying Li, Defu Li, Changdao Mu
The oxidized κ-carrageenans with different oxidation levels were prepared through the hydrogen peroxide and copper sulfate redox system. The oxidation level of oxidized κ-carrageenan was successfully controlled by adjusting the dosage of hydrogen peroxide. The results showed that the microtopography of oxidized κ-carrageenan changed from rough granules to smooth flakes, mainly resulting from the easily melting property of oxidized κ-carrageenan induced by introduced carboxyl and aldehyde groups. Especially, the antibacterial activity of oxidized κ-carrageenans against Gram-positive bacteria (Staphylococcus aureus and Listeria monocytogenes) and Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) was systematically investigated...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28820998/photosynthesis-of-alfalfa-medicago-sativa-in-response-to-landfill-leachate-contamination
#8
Lie Yang, Tiantian Sun, Yanli Liu, Houqing Guo, Lixin Lv, Jie Zhang, Chang Liu
Thousands of unlined landfills and open dumpsites have put great threat on the security of soil and ground water due to leachate leakage. Alfalfa is believed potential as a phytoremediation plant for leachate contamination based on strong root system and the excellent capacity of removing various kinds of pollutants. A lab-scale investigation was conducted to figure out the sensitiveness of alfalfa photosynthesis in response to leachate contamination. The results demonstrated that both of the maximum photosynthetic efficiency (Fv/Fm) and net photosynthetic rate (Pn) were slightly inhibited in the high-dosage group...
August 11, 2017: Chemosphere
https://www.readbyqxmd.com/read/28820996/exploring-ozonation-as-treatment-alternative-for-methiocarb-and-formed-transformation-products-abatement
#9
A Cruz-Alcalde, C Sans, S Esplugas
Despite the high toxicity and resistance to conventional water treatments exhibited by methiocarb (MC), there are no reports regarding the degradation of this priority pesticide by means of alternative purification technologies. In this work, the removal of MC by means of ozonation was studied for the first time, employing a multi-reactor methodology and neutral pH conditions. The second-order rate constants of MC reaction with molecular ozone (O3) and formed hydroxyl radicals (OH·) were determined to be 1...
August 12, 2017: Chemosphere
https://www.readbyqxmd.com/read/28820993/changing-profiles-of-bound-water-content-and-distribution-in-the-activated-sludge-treatment-by-nacl-addition-and-ph-modification
#10
Dong-Qin He, Ying-Jie Zhang, Chuan-Shu He, Han-Qing Yu
Currently the dewatering of activated sludge from wastewater treatment plants is a problem not well solved. Extracellular polymeric substances (EPS), including loosely bound EPS (LB-EPS) and tightly bound EPS (TB-EPS), are highly hydrated biopolymers and play important roles in sludge dewatering. In the present work, two types of treatments, i.e., salt addition and pH modification, were proposed to evaluate the effects of bound water content and its distribution on the dewatering performance of activated sludge...
August 10, 2017: Chemosphere
https://www.readbyqxmd.com/read/28820684/lack-of-efficacy-of-liposomal-amphotericin-b-against-acute-and-chronic-trypanosoma-cruzi-infection-in-mice
#11
Karl V Clemons, Raymond A Sobel, Marife Martinez, Rodrigo Correa-Oliveira, David A Stevens
Acute and chronic infection with Trypanosoma cruzi affects millions of people. The current therapeutic options are highly toxic and often not effective. Liposomal amphotericin B (LABORATORY) has been demonstrated previously to have some activity in murine models. In our studies, higher dosages given multiple times were tested for activity against acute or chronic disease, exploring whether intermittent and brief regimens could be effective, as might then prove useful in human, particularly outpatient, therapy...
August 14, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28820479/esterification-mechanism-of-bagasse-modified-with-glutaric-anhydride-in-1-allyl-3-methylimidazolium-chloride
#12
Huihui Wang, Wei Chen, Xueqin Zhang, Chuanfu Liu, Runcang Sun
The esterification of bagasse with glutaric anhydride could increase surface adhesion compatibility and the surface of derived polymers has the potential of immobilizing peptides or proteins for biomedical application. Due to its complicated components, the esterification mechanism of bagasse esterified with glutaric anhydride in ionic liquids has not been studied. In this paper, the homogenous esterification of bagasse with glutaric anhydride was comparatively investigated with the isolated cellulose, hemicelluloses, and lignin in 1-allyl-3-methylimidazolium chloride (AmimCl) to reveal the reaction mechanism...
August 18, 2017: Materials
https://www.readbyqxmd.com/read/28820468/resveratrol-in-hepatitis-c-patients-treated-with-pegylated-interferon-%C3%AE-2b-and-ribavirin-reduces-sleep-disturbance
#13
Manuela Pennisi, Gaetano Bertino, Caterina Gagliano, Michele Malaguarnera, Rita Bella, Antonio Maria Borzì, Roberto Madeddu, Filippo Drago, Giulia Malaguarnera
BACKGROUND: Hepatitis C virus infection and interferon treatment have shown to be risk factors for sleep disorder health-related quality of life. AIM: To determine whether the effects of resveratrol on sleep disorders were associated with different tests in subjects with chronic hepatitis C treated with Peg-IFN-α and RBV. PATIENTS AND METHODS: In this prospective, randomized, placebo controlled, double blind clinical trial, 30 subjects (Group A) with chronic hepatitis received Pegylated-Interferon-α2b (1...
August 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28820311/clinical-radiobiology-of-proton-therapy-modeling-of-rbe
#14
B Jones
PURPOSE: To better estimate relative biological effectiveness (RBE) in therapeutic proton beams by using a modeled approach, in order to improve their clinical safety and effectiveness. INTRODUCTION: Concerns exist about the 1.1 RBE used in proton therapy, since it may lead to unintentional over- and under-dosage in patients and so lead to unexpected clinical outcomes. Late reacting normal tissues (with low α/β values), might be overdosed if RBE >1.1; very radiosensitive tumors (with high α/β), might be under-dosed if RBE <1...
August 18, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28820036/efficacy-and-safety-of-the-early-addition-of-vasopressin-to-norepinephrine-in-septic-shock
#15
Drayton A Hammond, Julia Cullen, Jacob T Painter, Kelsey McCain, Oktawia A Clem, Amy L Brotherton, Divyan Chopra, Nikhil Meena
BACKGROUND: Delays in achievement of target mean arterial pressure (MAP) have been associated with increased mortality in patients with septic shock. Vasopressin may be added to norepinephrine to raise MAP or decrease norepinephrine dosage. The purpose of this study was to determine whether early initiation of vasopressin to norepinephrine resulted in a reduced time to target MAP compared to norepinephrine monotherapy. METHODS: This retrospective cohort study compared early addition of vasopressin within 4 hours of septic shock onset to norepinephrine versus initial norepinephrine monotherapy in medically, critically ill patients with septic shock admitted from May 2014 to October 2015...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28820005/inhibition-of-endocannabinoid-metabolizing-enzymes-in-peripheral-tissues-following-developmental-chlorpyrifos-exposure-in-rats
#16
Robert W Buntyn, Navatha Alugubelly, Rachel L Hybart, Afzaal N Mohammed, Carole A Nail, Greta C Parker, Matthew K Ross, Russell L Carr
Repeated developmental exposure to the organophosphate (OP) insecticide chlorpyrifos (CPF) inhibits brain fatty acid amide hydrolase (FAAH) activity at low levels, whereas at higher levels, it inhibits brain monoacylglycerol lipase (MAGL) activity. FAAH and MAGL hydrolyze the endocannabinoids anandamide (AEA) and 2-arachidonylglycerol (2-AG), respectively. Peripherally, AEA and 2-AG have physiological roles in the regulation of lipid metabolism and immune function, and altering the normal levels of these lipid mediators can negatively affect these processes...
January 1, 2017: International Journal of Toxicology
https://www.readbyqxmd.com/read/28819175/in-vivo-therapeutic-efficacy-of-frog-skin-derived-peptides-against-pseudomonas-aeruginosa-induced-pulmonary-infection
#17
Chen Chen, Maria Luisa Mangoni, Y Peter Di
Pseudomonas aeruginosa is an opportunistic and frequently drug-resistant pulmonary pathogen especially in cystic fibrosis sufferers. Recently, the frog skin-derived antimicrobial peptide (AMP) Esc(1-21) and its diastereomer Esc(1-21)-1c were found to possess potent in vitro antipseudomonal activity. Here, they were first shown to preserve the barrier integrity of airway epithelial cells better than the human AMP LL-37. Furthermore, Esc(1-21)-1c was more efficacious than Esc(1-21) and LL-37 in protecting host from pulmonary bacterial infection after a single intra-tracheal instillation at a very low dosage of 0...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819138/cooperative-interaction-of-bmp-signalling-and-foxn1-gene-dosage-determines-the-size-of-the-functionally-active-thymic-epithelial-compartment
#18
Jeremy B Swann, Brigitte Krauth, Christiane Happe, Thomas Boehm
Thymopoiesis strictly depends on the function of the Foxn1 transcription factor that is expressed in the thymic epithelium. During embryonic development, initial expression of the Foxn1 gene is induced in the pharyngeal endoderm by mesenchyme-derived BMP4 signals. Here, by engineering a time-delayed feedback system of BMP inhibition in mouse embryos, we demonstrate that thymopoiesis irreversibly fails if Foxn1 gene expression does not occur during a defining time span in mid-gestation. We also reveal an epistatic interaction between the extent of BMP signalling and the gene dosage of Foxn1...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819101/hypotension-in-icu-patients-receiving-vasopressor-therapy
#19
Bryce Yapps, Sungtae Shin, Ramin Bighamian, Jill Thorsen, Colleen Arsenault, Sadeq A Quraishi, Jin-Oh Hahn, Andrew T Reisner
Vasopressor infusion (VPI) is used to treat hypotension in an ICU. We studied compliance with blood pressure (BP) goals during VPI and whether a statistical model might be efficacious for advance warning of impending hypotension, compared with a basic hypotension threshold alert. Retrospective data were obtained from a public database. Studying adult ICU patients receiving VPI at submaximal dosages, we analyzed characteristics of sustained hypotension episodes (>15 min) and then developed a logistic regression model to predict hypotension episodes using input features related to BP trends...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819018/adjuvant-treatment-of-anogenital-warts-with-systemic-interferon-a-systematic-review-and-meta-analysis
#20
Lukas Westfechtel, Ricardo Niklas Werner, Corinna Dressler, Matthew Gaskins, Alexander Nast
BACKGROUND: Interferons are natural messenger proteins that are used to treat various disease entities. Due to their immunomodulating, antiviral and antiproliferative effects, the systemic administration of interferons after ablative treatment for anogenital warts (AGWs) has been advocated to increase clearance and decrease recurrence rates. However, studies investigating the efficacy of adjuvant systemic interferon have yielded inconsistent results. The objective of this systematic review and meta-analysis was to comprehensively assess and evaluate the available evidence from randomised controlled trials...
August 17, 2017: Sexually Transmitted Infections
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