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https://www.readbyqxmd.com/read/29453750/administration-of-lactobacillus-plantarum-lp62-to-dam-rats-at-the-end-of-delivery-and-during-lactation-affects-tgf-%C3%AE-1-level-and-nutritional-milk-composition-and-body-weight-of-pups
#1
Gladistone Correia Messias, Ana Marta Novais Rocha, Beatriz Manuela Silva Santos, Ana Marques Botelho, Dhaísa Cristhina Alves Silva, Erika Santos Porto, Marina Lima Dos Anjos, Rayra Almeida Sousa, Mara Viana Silva, Thainara Barros da Rocha, Aracely Vieira de Melo, Manoela Rios Trindade Carneiro, Nayonara Santana Aguiar, Patrícia Prado Santos, Erika Pereira de Souza, Mariluze Peixoto Cruz, Lucas Miranda Marques, Raquel Passos Rezende, Carla Cristina Romano, Ana Paula Uetanabaro, Gabriel Vinderola, Regiane Yatsuda
PURPOSE: Lactobacillus plantarum Lp62 is a lactic acid bacteria strain that has been isolated from cocoa beans and exhibited probiotic potential. The influence of oral administration of L. plantarum Lp62 on the growth of rat's pups; on yield, cytokines and milk composition was studied. METHODS: Lactobacillus plantarum Lp62 is a lactic acid bacteria strain that has been isolated from cocoa beans. It was administered daily by gavage to Wistar rats (n = 8), from the 7th day before delivery and for 20 days during lactation, in a concentration of 1...
February 16, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29451831/high-dose-perinatal-folic-acid-supplementation-alters-insulin-sensitivity-in-sprague-dawley-rats-and-diminishes-the-expression-of-adiponectin
#2
Ayodele Olufemi Morakinyo, Titilola Aderonke Samuel, Funmileyi Olubajo Awobajo, Gabriel Olorunleke Oludare, Adekunle Mofolorunso
The possible intake of folate in excess of the recommended upper levels is a matter of critical importance. This study was conducted to investigate the effects of prenatal and postnatal high folic acid supplementation (FAS) on glucose tolerance, insulin sensitivity, lipid metabolism, and expression of adiponectin in rats. The study included 20 female rats divided into two groups: control group and FAS group (receiving high folic acid supplemented diet). Both groups of female rats were mated and pregnancy confirmed...
February 16, 2018: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29446243/reproductive-health-in-women-following-abdominal-organ-transplant
#3
Monika Sarkar, Kate Bramham, Michael Moritz, Lisa Coscia
Fertility is commonly impaired in women with end-stage kidney and liver disease although most women will have restoration of fertility within one year of transplant. Family planning is therefore critical to discuss with reproductive-aged transplant recipients in the early post-transplant period, in order to ensure timely initiation of contraception, and optimal timing for conception. For women seeking pregnancy the risks to the mother, graft, and baby should be discussed, including evaluation of immunosuppression safety and potential for adjusting medications prior to conception...
February 15, 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/29444856/placental-physiology-monitored-by-hyperpolarized-dynamic-13-c-magnetic-resonance
#4
Stefan Markovic, Anne Fages, Tangi Roussel, Ron Hadas, Alexander Brandis, Michal Neeman, Lucio Frydman
Placental functions, including transport and metabolism, play essential roles in pregnancy. This study assesses such processes in vivo , from a hyperpolarized MRI perspective. Hyperpolarized urea, bicarbonate, and pyruvate were administered to near-term pregnant rats, and all metabolites displayed distinctive behaviors. Little evidence of placental barrier crossing was observed for bicarbonate, at least within the timescales allowed by 13 C relaxation. By contrast, urea was observed to cross the placental barrier, with signatures visible from certain fetal organs including the liver...
February 14, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29444356/long-chain-polyunsaturated-fatty-acids-decline-rapidly-in-milk-from-mothers-delivering-extremely-preterm-indicating-the-need-for-supplementation
#5
Anders K Nilsson, Chatarina Löfqvist, Svetlana Najm, Gunnel Hellgren, Karin Sävman, Mats X Andersson, Lois E H Smith, Ann Hellström
AIM: Our aim was perform an in-depth analysis of the composition of fatty acids in milk from mothers delivering extremely preterm babies. We investigated longitudinal changes in milk fatty acid profiles and the relationship between several types of fatty acids, including omega-3 and omega-6. METHODS: Milk samples were collected at three stages of lactation from 78 mothers who delivered at less than 28 weeks of pregnancy at the Sahlgrenska University Hospital, Gothenburg, Sweden, from April 2013 to September 2015...
February 14, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29443421/diabetes-uk-evidence-based-nutrition-guidelines-for-the-prevention-and-management-of-diabetes
#6
P A Dyson, D Twenefour, C Breen, A Duncan, E Elvin, L Goff, A Hill, P Kalsi, N Marsland, P McCardle, D Mellor, L Oliver, K Watson
A summary of the latest evidence-based nutrition guidelines for the prevention and management of diabetes is presented. These guidelines are based on existing recommendations last published in 2011, and were formulated by an expert panel of specialist dietitians after a literature review of recent evidence. Recommendations have been made in terms of foods rather than nutrients wherever possible. Guidelines for education and care delivery, prevention of Type 2 diabetes, glycaemic control for Type 1 and Type 2 diabetes, cardiovascular disease risk management, management of diabetes-related complications, other considerations including comorbidities, nutrition support, pregnancy and lactation, eating disorders, micronutrients, food supplements, functional foods, commercial diabetic foods and nutritive and non-nutritive sweeteners are included...
February 14, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29431474/maternal-carbamazepine-therapy-and-unusual-adverse-effects-in-a-breastfed-infant
#7
Roberto Antonucci, Laura Cuzzolin, Alessandra Manconi, Claudio Cherchi, Anna Maria Oggiano, Cristian Locci
BACKGROUND: Usually, no adverse effects are observed in breastfed infants whose mothers are treated with the anti-epileptic carbamazepine. In this article, we described unusual short-term adverse effects observed in a young infant after exposure to carbamazepine during pregnancy and lactation. CASE REPORT: A 40-day-old female infant, born at term, was admitted to the Pediatric Clinic at University of Sassari, Italy, for recurrent regurgitations and vomiting. She was breastfed since birth and her mother was under chronic carbamazepine therapy...
February 12, 2018: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29428754/follicular-dynamics-circulating-progesterone-and-fertility-in-holstein-cows-synchronized-with-reused-intravaginal-progesterone-implants-that-were-sanitized-by-autoclave-or-chemical-disinfection
#8
L F Melo, P L J Monteiro, A B Nascimento, J N Drum, C Spies, A B Prata, M C Wiltbank, R Sartori
This experiment aimed to compare circulating progesterone (P4), follicular dynamics, and fertility during reuse of intravaginal P4 implants that were sanitized by autoclave or chemical disinfection in lactating Holstein cows submitted to fixed-time artificial insemination (FTAI). For this, 123 primiparous and 226 multiparous cows from 2 farms, averaging (mean ± standard deviation) 163.9 ± 141.9 d in milk, 35.7 ± 11.3 kg of milk/d, and a body condition score of 2.9 ± 0.5, were enrolled in the study. Cows were randomly assigned to 1 of 2 treatments using a completely randomized design and each cow received a reused implant (1...
February 7, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29428749/effect-of-altering-the-type-of-dietary-carbohydrate-early-postpartum-on-reproductive-performance-and-milk-production-in-pasture-grazed-dairy-cows
#9
S McDougall, S Leane, S T Butler, J R Roche, C R Burke
The objective of this study was to assess the effect of increasing dietary starch for approximately 30 d postpartum on reproduction outcomes in pasture-grazed, seasonal-calving dairy cows. Cows (n = 948) from 3 commercial herds were blocked by age (2, 3, and >3 yr), breed, and expected calving date and randomly assigned to 1 of 2 postpartum treatment groups: high starch (34.7 ± 1.9% nonstructural carbohydrate; mean ± SD) or low starch (22.5 ± 0.4% nonstructural carbohydrate). The high-starch group in all 3 farms received 4...
February 7, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29428703/the-contribution-of-total-and-free-iodothyronines-to-welfare-maintenance-and-management-stress-coping-in-ruminants-and-equines-physiological-ranges-and-reference-values
#10
REVIEW
Adriana Ferlazzo, Cristina Cravana, Esterina Fazio, Pietro Medica
In order to acquire a pattern of thyroid involvement in welfare maintenance in Ruminants and Equines, this review summarizes data concerning the reference values of total and free iodothyronines and their modifications in physiological conditions and in different management conditions (pregnancy, lactation, weaning, growth, isolation, restraint, shearing, confinement and transportation). Thyroidal and extrathyroidal tissues efficiently respond to management practices, giving a differentiated contribution to circulating iodothyronine changes...
February 2, 2018: Research in Veterinary Science
https://www.readbyqxmd.com/read/29423909/perinatal-high-fat-diet-and-early-life-methyl-donor-supplementation-alter-one-carbon-metabolism-and-dna-methylation-in-the-brain
#11
S E McKee, S Zhang, L Chen, J D Rabinowitz, T M Reyes
One carbon metabolism is regulated by the availability of nutrients known as methyl donors, and disruption of this pathway can affect multiple physiological systems. DNA methylation, critical for the regulation of gene expression, is linked to one carbon metabolism, and can be altered by perinatal diet. In the current study, dams (n=12/group) were fed HF or standard control (SC) diet through pregnancy and lactation, and male and female offspring were then fed either SC or methyl donor supplemented diet (MDS) between 3 and 6 weeks of age (n=20-26/group)...
February 9, 2018: Journal of Neurochemistry
https://www.readbyqxmd.com/read/29421836/drugs-in-pregnancy-and-lactation-medications-used-in-swiss-obstetrics
#12
Larissa Schenkel, Ana Paula Simões-Wüst, Irene Hösli, Ursula von Mandach
BACKGROUND: In order to improve the safety for drugs in pregnancy and lactation, data on the clinical practice must be collected and validated. METHODS: Data on the medications routinely used were requested from the university hospitals for obstetrics and the non-university perinatal centres in Switzerland and recommendations and guidelines of scientific societies for the various fields of application were sought. RESULTS: Part I: For during pregnancy and the peripartal period respectively, 69 and 21 different active constituents of medications were identified from at least 4 centres...
February 8, 2018: Zeitschrift Für Geburtshilfe und Neonatologie
https://www.readbyqxmd.com/read/29420538/th-pok-regulates-mammary-gland-lactation-through-mtor-srebp-pathway
#13
Rui Zhang, Huimin Ma, Yuan Gao, Yanjun Wu, Yuemei Qiao, Ajun Geng, Cheguo Cai, Yingying Han, Yi Arial Zeng, Xiaolong Liu, Gaoxiang Ge
The Th-inducing POK (Th-POK, also known as ZBTB7B or cKrox) transcription factor is a key regulator of lineage commitment of immature T cell precursors. It is yet unclear the physiological functions of Th-POK besides helper T cell differentiation. Here we show that Th-POK is restrictedly expressed in the luminal epithelial cells in the mammary glands that is upregulated at late pregnancy and lactation. Lineage restrictedly expressed Th-POK exerts distinct biological functions in the mammary epithelial cells and T cells in a tissue-specific manner...
February 8, 2018: PLoS Genetics
https://www.readbyqxmd.com/read/29411149/pharmacological-treatment-of-attention-deficit-hyperactivity-disorder-during-pregnancy-and-lactation
#14
REVIEW
Asher Ornoy
INTRODUCTION: Attention deficit/hyperactivity disorder (ADHD) is a neurobehavioral problem found in 2-5% of adults. Stimulants and drugs that affect the dopaminergic, noradrenergic and/or serotonergic systems are effective treatment and are increasingly prescribed to women at child bearing age. It is consequently important that reliable information on the safety of these drugs in pregnancy is available so that appropriate therapeutic choices can be made. RESULTS: The data on stimulants (methylphenidate and amphetamines) are generally showing that there is no increase in the rate of major congenital anomalies...
February 6, 2018: Pharmaceutical Research
https://www.readbyqxmd.com/read/29409795/medicinal-foods-and-beverages-among-maasai-agro-pastoralists-in-northern-tanzania
#15
Casey J Roulette, Efrem-Fred A Njau, Marsha B Quinlan, Robert J Quinlan, Douglas R Call
ETHNOPHARMACOLOGICAL RELEVANCE: Pastoralist Maasai populations of east Africa use several different wild plants as dietary and medicinal additives in beverages (soups and teas), yet little is known about how the plants used and the rationales for use compare and contrast across different Maasai beverages, including how gender specific dietary and health concerns structure patterns of intake. AIM OF THE STUDY: We investigated three Maasai beverages: almajani (tea or herbal infusion); motorí (traditional soup); and okiti (psychoactive herbal tea)...
February 1, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29408965/impacts-of-estrus-expression-and-intensity-during-a-timed-ai-protocol-on-variables-associated-with-fertility-and-pregnancy-success-in-bos-indicus-influenced-beef-cows
#16
A D Rodrigues, R F Cooke, R S Cipriano, L G T Silva, R L A Cerri, L H Cruppe, M Meneghetti, K G Pohler, J L M Vasconcelos
This experiment evaluated the impacts of estrus expression and intensity, estimated by physical activity during a timed-AI protocol, on reproductive performance of Bos indicus-influenced beef cows. A total of 290 lactating, primiparous and multiparous non-pregnant Nelore × Angus cows received a 2 mg injection of estradiol benzoate and an intravaginal progesterone (P4) releasing device (CIDR) on d -11, a 12.5 mg injection of PGF2α on d -4, CIDR removal in addition to 0.6 mg injection of estradiol cypionate and 300 IU injection of eCG on d -2, and timed-AI on d 0...
February 2, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29407004/breast-milk-is-conditionally-perfect
#17
Miriam Erick
Breast milk is the universal preferred nutrition for the newborn human infant. New mother have been encouraged to exclusively breastfeed by health care professionals and consumer-advocacy forums for years, citing "breast milk is the perfect food". The benefits are numerous and include psychological, convenience, economical, ecological and nutritionally superior. Human milk is a composite of nutritional choices of the mother, commencing in the pre-conceptual era. Events influencing the eventual nutritional profile of breast milk for the neonate start with pre-conceptual dietary habits through pregnancy and finally to postpartum...
February 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29403301/early-exposure-to-distinct-sources-of-lipids-affects-differently-the-development-and-hepatic-inflammatory-profiles-of-21-day-old-rat-offspring
#18
Laís Vales Mennitti, Lila Missae Oyama, Aline Boveto Santamarina, Claudia Maria da Penha Oller do Nascimento, Luciana Pellegrini Pisani
Introduction: Maternal diet composition of fatty acids during pregnancy and lactation seems to modify the fetal programming, epigenetic pattern and offspring phenotype. Aim: Herein, we investigated the effects of maternal consumption of normal-fat diets with distinct lipid sources during pregnancy and lactation on the somatic development and proinflammatory status of 21-day-old rat offspring. Materials and Methods: On the first day of pregnancy, female Wistar rats were divided into four groups as follows: soybean oil (M-SO), lard (M-L), hydrogenated vegetable fat (M-HVF) and fish oil (M-FO)...
2018: Journal of Inflammation Research
https://www.readbyqxmd.com/read/29400628/reproductive-factors-influencing-bone-mineral-density-in-postmenopausal-women
#19
Fatemeh Mohammadi, Jamileh Amirzadeh Iranagh, Seyedeh Ameneh Motalebi, Tengku Aizan Hamid
OBJECTIVE: This study examined the relationship between reproductive characteristics and bone mineral density in postmenopausal women who had been referred to the menopause clinics of the National Population and Family Development Board and of the Hospital Kuala Lumpur from July 2011 to January 2012. METHOD: The participants of this study were 201 postmenopausal Malaysian women aged 45-71 years. Some socio-demographic, life style and reproductive factors were recorded...
February 5, 2018: Women & Health
https://www.readbyqxmd.com/read/29396666/cross-reactivity-between-muc1-antigen-and-mca-false-elevation-of-serum-ca-15-3-level-in-pregnant-and-lactating-women-by-ma695-ma552-based-assay
#20
Guangshu Liang, Xuqian Fang, Xiaoyi Lin, Xiaojing Feng, Huangying Lu, Yinglei Wan, Zhidong Gu
PURPOSE: Cancer antigen 153 (CA 15-3) is one of the most commonly used biomarkers of breast cancer. However, elevated CA 15-3 is reported in pregnant and lactating women more frequently on Beckman DxI 800 immunoassay system (Ma695-Ma552 antibody pair) than on Abbott ARCHITECT system (115D8-DF3 antibody pair) in laboratory methodological evaluation. We conducted this study in order to figure out the reason behind this phenomenon. METHODS: Serum CA 15-3 concentration was analyzed in 426 subjects, including 180 patients with breast cancer, 121 patients with benign breast disease, and 125 healthy volunteers (45 pregnant and 80 non-pregnant women)...
February 2, 2018: Breast Cancer Research and Treatment
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