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Geriatric neurology

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https://www.readbyqxmd.com/read/29792393/outcomes-of-transcatheter-aortic-valve-implantation-compared-with-surgical-aortic-valve-replacement-in-geriatric-patients-with-chronic-kidney-disease
#1
Linda Shavit, Shuli Silberman, Rachel Tauber, Ofer Merin, Daniel Bitran, Daniel Fink
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is a less invasive treatment modality for patients with severe aortic valve stenosis (AS) who are at a higher risk if they have surgery. Preoperative chronic kidney disease (CKD) influences outcomes of cardiac surgery and is associated with a higher mortality and more complicated hospital course. The aims of our study were to evaluate the comparative outcomes of TAVI versus surgical aortic valve replacement (SAVR) in geriatric patients with preoperative CKD...
May 24, 2018: Clinical Nephrology
https://www.readbyqxmd.com/read/29763856/hospital-readmission-risks-in-older-adults-following-inpatient-subacute-care-a-six-month-follow-up-study
#2
Den-Ching A Lee, Cylie Williams, Aislinn F Lalor, Ted Brown, Terry P Haines
BACKGROUND: High rates of unplanned hospital readmissions are a burden on healthcare systems and individuals. This study examined factors at, and after initial hospital discharge and their associations with unplanned hospital readmission for older adults up to six months post-discharge from subacute care. METHODS: Older subacute care patients were surveyed prior to discharge, and assessed monthly post-discharge for six months. Data included the Geriatric Depression Scale, Phone-Fitt sub-scales, Friendship Scale, modified Lubben Social Network Scale, unplanned hospital readmission, self-reported physical capacity and falls in the last month were collected...
May 9, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29755356/anti-parkinson-potential-of-silymarin-mechanistic-insight-and-therapeutic-standing
#3
REVIEW
Hammad Ullah, Haroon Khan
Parkinson's disease (PD) involves aggregation of α-synuclein and progressive loss of dopaminergic neurons. Pathogenesis of PD may also be related to one's genetic background. PD is most common among geriatric population and approximately 1-2% of population suffers over age 65 years. Currently no successful therapies are in practice for the management of PD and available therapies tend to decrease the symptoms of PD only. Furthermore, these are associated with diverse range of adverse effects profile. The neuroprotective effects of polyphenols are widely studied and documented...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29740312/emotion-detection-deficits-and-decreased-empathy-in-patients-with-alzheimer-s-disease-and-parkinson-s-disease-affect-caregiver-mood-and-burden
#4
Maria Martinez, Namita Multani, Cassandra J Anor, Karen Misquitta, David F Tang-Wai, Ron Keren, Susan Fox, Anthony E Lang, Connie Marras, Maria C Tartaglia
Background : Changes in social cognition occur in patients with Alzheimer's disease (AD) and Parkinson's disease (PD) and can be caused by several factors, including emotion recognition deficits and neuropsychiatric symptoms (NPS). The aims of this study were to investigate: (1) group differences on emotion detection between patients diagnosed with AD or PD and their respective caregivers; (2) the association of emotion detection with empathetic ability and NPS in individuals with AD or PD; (3) caregivers' depression and perceived burden in relation to patients' ability to detect emotions, empathize with others, presence of NPS; and (4) caregiver's awareness of emotion detection deficits in patients with AD or Parkinson...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29720293/using-structural-equation-modeling-to-detect-response-shift-in-quality-of-life-in-patients-with-alzheimer-s-disease
#5
Xuxia Wang, Xiaomeng Xu, Hongjuan Han, Runlian He, Liye Zhou, Ruifeng Liang, Hongmei Yu
ABSTRACTBackground:Our study aims to detect different types of response shifts (RS) and true changes of quality of life (QOL) measurement in patients with Alzheimer's disease (AD) using structural equation modeling (SEM) in domain level. METHODS: Patients with AD aged over 60 years old were collected from the Department of Neurology and Geriatrics in Taiyuan Central Hospital, China. The 12-item Short Form (SF-12) Health Survey was measured in 238 patients with AD prior to hospitalization and one month following discharge...
May 3, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/29710725/prevalence-of-dementia-and-associated-risk-factors-a-population-based-study-in-the-philippines
#6
Jacqueline Dominguez, Ma Fe de Guzman, Macario Reandelar, Thien Kieu Thi Phung
BACKGROUND: The Philippines is experiencing rapid demographic aging and with it, the dementia epidemic. Prevalence of dementia and associated risk factors have not been studied in the Philippines. OBJECTIVES: The study aimed to provide a reliable estimate of dementia prevalence and identify associated risk factors in the Filipino population. METHODS: 1460 participants 60 years and older were randomly selected from the Marikina City's senior registry...
April 25, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29682233/personality-factors-and-cognitive-functioning-in-elderly-with-parkinson-s-disease
#7
Neusa Maria de Oliveira Chardosim, Camila Rosa Oliveira, Manuela Polidoro Lima, Marianne Farina, Valéria Gonzatti, Dalton Breno Costa, Aline Sória Pereira, Luis Henrique Paloski, Tatiana Quarti Irigaray, Irani Iracema de Lima Argimon
Parkinson's disease (PD) is a chronic and progressive neurological disease, resulting from cell degeneration in the substantia nigra, responsible for the production of dopamine. Objective: This study aimed to characterize the cognitive functioning, personality factors and prevalence of depressive and anxiety symptoms in individuals with Parkinson's disease (PD). Furthermore, this study sought to analyze whether personality factors were predictors of cognitive functioning. Methods: The sample consisted of 30 elderly with PD...
January 2018: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29682229/cognitive-deficits-in-older-adults-with-mild-cognitive-impairment-in-a-two-year-follow-up-study
#8
Camila de Assis Faria, Heloisa Veiga Dias Alves, Eduarda Naidel Barboza E Barbosa, Helenice Charchat-Fichman
Characterizing cognitive decline in older adults with MCI over time is important to identify the cognitive profile of those who convert to dementia. Objective: This study examined the two-year cognitive trajectory of elderly adults diagnosed with MCI, from geriatrics and neurology outpatient clinics of a public hospital in Rio de Janeiro. Methods: 62 older adults with MCI were submitted to a neuropsychological battery and re-evaluated after two years. The Mann-Whitney U test was employed to assess differences between groups with respect to education, functioning, the Geriatric Depression Scale and diagnosis...
January 2018: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29649847/-special-palliative-care-in-patients-with-non-oncological-diseases
#9
Claudia Bausewein
Palliative medicine has become an integral part of the German healthcare system in recent years. However, patients with non-malignant diseases have less access to palliative care than patients with oncological diseases. These patients comprise a heterogeneous group of chronic lung and heart diseases, neurological and geriatric diseases. Their symptom burden and their palliative care needs are similar to those of oncological patients, but earlier in the disease process. Physical aspects of the disease process are different from psychological, social and spiritual aspects...
April 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29643881/urinary-tract-infections-in-the-geriatric-patients
#10
Yesim Alpay, Nevil Aykin, Pinar Korkmaz, Hakki Mustafa Gulduren, Figen Cevik Caglan
Objective: Urinary tract infections (UTI) are the second most common infection in geriatric population. This study investigated clinical findings, diagnostic approaches, complicating factors, prognosis, causative microorganisms and antimicrobial susceptibility in geriatric patients diagnosed with UTI. Methods: A total of 140 hospitalised patients with UTIs were evaluated within three years between January 2011-January 2015 at the Eskisehir Yunus Emre State Hospital...
January 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29628887/disease-specific-aspects-of-malnutrition-in-neurogeriatric-patients
#11
REVIEW
Tino Prell, Caroline Perner
Malnutrition in elderly patients is a common condition. Nevertheless, there is evidence on specific risk factors and problems of malnutrition in geriatric patients with neurological diseases. In this review, we summarize recent knowledge on malnutrition in different neurological diseases with a focus on elderly patients. This overview also provides strategies for a more specific and profound assessment of neurogeriatric patients to improve identification and treatment of malnutrition. Early and consequent treatment of malnutrition can lead to a decreased progression of the neurological disease and to a better quality of life in geriatric patients...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29623160/geriatric-basics-for-the-neurohospitalist
#12
REVIEW
Josef G Heckmann, Jörg Kraus, Christoph J G Lang
Due to the increasing age of the population, neurohospitalists are more frequently caring for old and very old people. Fundamental definitions and topics related to geriatric medicine are therefore of particular importance. In this review, common issues encountered in geriatric patients hospitalized on the neurology service are discussed. Focus is put on the geriatric assessment, multiprofessional diagnostic and therapeutic procedures, geriatric syndromes, pharmacotherapy of the aged, delirium, pain, and palliative management as they are relevant for the neurohospitalist...
April 2018: Neurohospitalist
https://www.readbyqxmd.com/read/29620588/atlas-fractures-diagnosis-current-treatment-recommendations-and-implications-for-elderly-patients
#13
Richard M Smith, Amit K Bhandutia, Julio J Jauregui, Mark Shasti, Steven C Ludwig
Fractures of the C1 vertebrae (atlas) are commonly the result of falls and other trauma, which cause hyperextension, or axial compression of the cervical spine. Although historically thought as a benign injury with lower neurological risks, current data suggests that this may not hold true for geriatric patients (aged 65 y and older) who may be predisposed to these fractures even after lower-energy trauma such as ground-level falls. Advancements in orthopedic trauma care has increased our diagnostic abilities to identify and manage patients with C1 fractures and other upper cervical spine trauma...
April 3, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29614641/neuropsychiatric-symptoms-and-the-diagnostic-stability-of-mild-cognitive-impairment
#14
Michael A Sugarman, Michael L Alosco, Yorghos Tripodis, Eric G Steinberg, Robert A Stern
BACKGROUND: Mild cognitive impairment (MCI) is an intermediate diagnosis between normal cognition (NC) and dementia, including Alzheimer's disease (AD) dementia. However, MCI is heterogeneous; many individuals subsequently revert to NC while others remain stable at MCI for several years. Identifying factors associated with this diagnostic instability could assist in defining clinical populations and determining cognitive prognoses. OBJECTIVE: The current study examined whether neuropsychiatric symptoms could partially account for the temporal instability in cognitive diagnoses...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29608779/interdisciplinary-home-visits-for-individuals-with-advanced-parkinson-s-disease-and-related-disorders
#15
Jori Fleisher, William Barbosa, Meghan M Sweeney, Sarah E Oyler, Amy C Lemen, Arash Fazl, Mia Ko, Talia Meisel, Naomi Friede, Geraldine Dacpano, Rebecca M Gilbert, Alessandro Di Rocco, Joshua Chodosh
Parkinson's disease (PD) is a complex, multisymptom, neurodegenerative disease affecting primarily older adults. With progression, many individuals become homebound and removed from coordinated, expert care, resulting in excess morbidity, mortality, and healthcare expenditures in acute care settings and institutions. Home visit care models have achieved the triple aim of improving individual and population health while reducing costs in many frail, community-dwelling geriatric cohorts. This study details a novel, interdisciplinary home visit program specifically designed for individuals with PD and related disorders and their family caregivers built upon best practice principles in the care of multimorbid older adults...
April 2, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29580107/erratum
#16
(no author information available yet)
Narayan SW, Jamieson HA, Nishtala PS. Evaluation of the National Minimum Data Set for Neurological Conditions in Older Adults. Journal of Geriatric Psychiatry and Neurology. 2017; 30(6):331-336. doi: 10.1177/0891988717732154 In the above-referenced article, the corresponding author's qualifications were incorrectly listed as BPharm, MPharm, PG DipClinPharm, PhD which is an overlap of another author's qualifications. The online and print versions have been updated to reflect the correct qualification of the corresponding author as BPharm, MPharmPrac...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/29559949/impaired-quality-of-life-and-need-for-palliative-care-in-a-german-cohort-of-advanced-parkinson-s-disease-patients
#17
Martin Klietz, Amelie Tulke, Lars H Müschen, Lejla Paracka, Christoph Schrader, Dirk W Dressler, Florian Wegner
Background: Parkinson's disease (PD) is the second most frequent neurodegenerative disease of the elderly. Patients suffer from various motor and non-motor symptoms leading to reduced health-related quality of life (HRQOL) and an increased mortality. Their loss of autonomy due to dementia, psychosis, depression, motor impairments, falls, and swallowing deficits defines a phase when palliative care interventions might help to sustain or even improve quality of life. Objective: The aim of this study was to investigate the current status of palliative care implementation and quality of life in a local cohort of advanced PD patients in order to frame and improve future care...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29539602/stroke-referrals-from-nursing-homes-high-rate-of-mimics-and-late-presentation
#18
Markus Kneihsl, Christian Enzinger, Kurt Niederkorn, Gerit Wünsch, Lisa Müller, Valeriu Culea, Andreas Lueger, Franz Fazekas, Thomas Gattringer
BACKGROUND: Stroke has become a treatable condition with increasing evidence of treatment benefits in older people. However, stroke mimics in geriatric patients are especially prevalent, causing incorrect suspicion and consecutive burden to patients and emergency room resources. We therefore examined the dimension of this problem by investigating emergency room admissions from nursing homes for suspected stroke. METHODS: We performed a retrospective cohort study of all nursing home residents who were admitted to the neurological emergency room of our primary and tertiary care university hospital between 2013 and 2015...
2018: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/29535509/health-status-health-behaviors-and-the-ability-to-perform-everyday-activities-in-poles-aged-%C3%A2-65-years-staying-in-their-home-environment
#19
Izabela Wróblewska, Iwona Zborowska, Anna Dąbek, Robert Susło, Zuzanna Wróblewska, Jarosław Drobnik
Background: The incidence of chronic diseases increases with age; about 73% of people who are aged ≥60 years suffer from at least 1 chronic disease, and among those older than 70 years, chronic diseases afflict more than >84% of the population. According to epidemiological data, at least 4 chronic disease types coexist in senior citizens, causing their disability. These are mainly cardiovascular diseases; motor system diseases; ophthalmological, auditory, neurological, and mental diseases; and mental impairment...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29512265/relationship-between-number-of-drugs-and-duration-of-hospital-stay-in-older-patients-with-neuromuscular-diseases
#20
Shohei Nishida, Yuichi Hayashi, Akio Suzuki, Ryo Kobayashi, Takashi Inuzuka, Yoshinori Itoh
AIM: Older patients are considered to be at high risk for developing adverse drug reactions (ADR), because they commonly receive multidrug therapy despite changes in pharmacokinetic function with age. In the present study, we assessed the relationship between the number of prescribed drugs and the incidence of ADR or the time to discharge in older patients with neuromuscular disease. METHODS: A retrospective study was carried out among 135 older patients (aged ≥65 years) who were admitted to the neurology ward from October 2007 through December 2011...
March 7, 2018: Geriatrics & Gerontology International
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