Eva Peñas-LLedó, Enrique Terán, Marta Sosa-Macías, Carlos Galaviz-Hernández, Jose-Pedro Gil, Sujit Nair, Shyam Diwakar, Isabel Hernández, Julio Lara-Riegos, Ronald Ramírez-Roa, Ignacio Verde, Eduardo Tarazona-Santos, Juan Molina-Guarneros, Graciela Moya, Lembit Rägo, Adrián LLerena
PURPOSE: The symposium Health and Medicines in Indigenous Populations of America was organized by the Council for International Organizations of Medical Sciences (CIOMS) Working Group on Clinical Research in Resource-Limited Settings (RLSs) and the Ibero-American Network of Pharmacogenetics and Pharmacogenomics (RIBEF). It was aimed to share and evaluate investigators' experiences on challenges and opportunities on clinical research and pharmacogenetics. METHODS: A total of 33 members from 22 countries participated in 2 sessions: RIBEF studies on population pharmacogenetics about the relationship between ancestry with relevant drug-related genetic polymorphisms and the relationship between genotype and phenotype in Native Americans (session 1) and case examples of clinical studies in RLSs from Asia (cancer), America (diabetes and women health), and Africa (malaria) in which the participants were asked to answer in free text their experiences on challenges and opportunities to solve the problems (session 2)...
August 8, 2020: Clinical Therapeutics