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Self awarness

Lesley K Rao, Alicia M Flaker, Christina C Friedel, Evan D Kharasch
BACKGROUND: At therapeutic concentrations, cytochrome P4502B6 (CYP2B6) is the major P450 isoform catalyzing hepatic ketamine N-demethylation to norketamine in vitro. The CYP2B6 gene is highly polymorphic. The most common variant allele, CYP2B6*6, is associated with diminished hepatic CYP2B6 expression and catalytic activity compared with wild-type CYP2B6*1/*1. CYP2B6.6, the protein encoded by the CYP2B6*6 allele, and liver microsomes from CYP2B6*6 carriers had diminished ketamine metabolism in vitro...
October 20, 2016: Anesthesiology
Işıl Bavunoğlu, Musa Balta, Zeynep Türkmen
BACKGROUND: There is an increasing interest in herbal products as a self-medication method in recent years. Some plant extracts either turn into drugs over time or are consumed directly without treatment. One of these plants is Nerium oleander L., which is a potentially lethal plant, since it has cardiac glycosides. However, numerous researches of its extracts have been performed against cancer cell lines in recent literature. This contradiction leads to misinterpretation and induces the prevalence of intoxication or fatal cases...
September 2016: Balkan Medical Journal
Joshua D Billings, Dvora L Joseph Davey, Kelika A Konda, Claire C Bristow, Jeremy Chow, Jeffrey D Klausner, Carlos F Cáceres
The aim of the study was to identify factors associated with undiagnosed human immunodeficiency virus (HIV) infection among men who have sex with men (MSM) and male-to-female transgender women in Lima, Peru.We analyzed characteristics of 378 MSM and transgender women recruited from 2 sexually transmitted infection (STI) clinics in Lima, Peru. Descriptive analyses compared: (A) HIV-uninfected, (B) previously undiagnosed HIV-infected, and (C) previously diagnosed HIV-infected participants. Multivariable logistic regression models identified: (1) correlates of previously undiagnosed HIV-infection among participants thought to be HIV-uninfected (B vs A); and (2) correlates of previously undiagnosed HIV-infection among HIV-infected participants (B vs C)...
October 2016: Medicine (Baltimore)
Nirav Patel, Justine Pierson, Timothy Lee, Bruce Mast, Bernard T Lee, Irene Estores, Dhruv Singhal
BACKGROUND: Integrative medicine (IM) is currently used by 40% of Americans. Our objective is to examine the prevalence and perception of IM utilization in patients being evaluated for elective plastic surgery. METHODS: In July 2014, 402 consecutive patients presenting to plastic surgery clinics at the University of Florida, Veterans Affairs (VA), and Private Practices in Gainesville, Florida were requested to complete a survey regarding utilization of and attitudes towards IM...
October 17, 2016: Annals of Plastic Surgery
Ejiofor T Ugwu, Casmir Jg Orjioke, Ekenechukwu E Young
BACKGROUND: Self monitoring of blood glucose (SMBG) is a useful adjunct to lifestyle modification and medications for optimal management of type 2 diabetes mellitus (DM). This study was aimed at evaluating the practice, cost and associations of SMBG in subjects with type 2 DM in Enugu, Nigeria. METHODS: In a cross-sectional survey conducted at the diabetes clinic in three hospitals, 366 type 2 diabetic subjects aged 18-65 years were consecutively interviewed. Socio-demographic and clinical information were documented and glycated hemoglobin was performed for all the participants...
October 14, 2016: Current Diabetes Reviews
Victor E Ezeugwu, Neera Garga, Patricia J Manns
PURPOSE: Understanding the determinants of sedentary behaviour (sitting or lying with low energy expenditure) in stroke survivors can enhance the development of successful behaviour change strategies. This qualitative study explored the perceptions of stroke survivors about sedentary behaviour and ways in which it can be changed. METHODS: An interpretative qualitative inquiry was used with thematic analysis of interview data. Interviews were conducted using a semi-structured guide with 13 stroke survivors...
October 19, 2016: Disability and Rehabilitation
Ruth Still, Debbie Marais, Jenna Louise Hollis
There is a lack of knowledge and understanding of the term exclusive breastfeeding (EBF) among health professionals. The purpose of this review was to examine the best available literature on mothers' understanding of the term EBF. A systematic search of eight electronic databases (Medline, Embase, CINAHL, CDSR, CENTRAL, Cab Abstracts, Scopus and African Index Medicus) was conducted (Protocol registration in PROSPERO: CRD42015019402). All study designs were eligible for inclusion. Studies were included if they: (1) involved mothers aged 18 years or older; (2) assessed mothers' knowledge/understanding/awareness of the term 'EBF'; (3) used the 1991 WHO definition of EBF and (4) were published between 1988 and 2015...
October 18, 2016: Maternal & Child Nutrition
Christine M Eisenhauer, Patricia A Hageman, Sheri Rowland, Betsy J Becker, Susan A Barnason, Carol H Pullen
OBJECTIVE: To examine rural men's use and perceptions of mobile and wireless devices to self-monitor eating and physical activity (mHealth). DESIGN AND SAMPLE: Men in this 3-week pilot study used FitBit One(®) to log daily food intake and monitor activity. A companion application (app) allowed activity monitoring of fellow participants. Health-related text messages were received 1-3 times daily. A purposive sample of 12 rural men (ages 40-67) was recruited by community leaders...
October 18, 2016: Public Health Nursing
Esther I Bernhofer, Rose Hosler, Diana Karius
Providing optimal pain care for patients is essential to the work of nursing and a measure of patient satisfaction prompting some hospitals to offer pain management classes for clinicians. Although nurses generally do well on knowledge tests after attending a pain class, actual improvement in pain care for patients may not occur. The personal values of the clinician may be a key driver of pain-management decision making. Therefore, a segment on how clinicians' personal values influence pain care decisions was added to a large Midwestern hospital's pain management class...
October 15, 2016: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
Kylee Trevillion, Jill Domoney, Andrew Pickles, Debra Bick, Sarah Byford, Margaret Heslin, Jeannette Milgrom, Rachel Mycroft, Carmine Pariante, Elizabeth Ryan, Myra Hunter, Louise Michele Howard
BACKGROUND: Depression is a common antenatal mental disorder and is associated with an increased risk of adverse effects on the fetus and significant morbidity for the mother; if untreated it can also continue into the post-natal period and affect mother-infant interactions. There has been little research evaluating the effectiveness or cost-effectiveness of antenatal psychological interventions for antenatal depression, particularly for mild to moderate disorders. International guidelines recommend a stepped care approach starting with Guided Self Help, and the aim of this exploratory trial is to investigate Guided Self Help modified for pregnancy...
October 18, 2016: Trials
Leslie Swartz, Jason Bantjes, Bradley Knight, Greg Wilmot, Wayne Derman
PURPOSE: To describe how athletes with disabilities talk about their experiences of participating in competitive disability sport in South Africa. METHOD: In-depth semi-structured interviews were conducted with 20 athletes with disabilities. Data were analysed via thematic content analysis using an inductive data driven process. RESULTS: Participants described their involvement in competitive sport as a positive experience; they described it as a catalyst for the recasting of identities and reframing an understanding of physical impairment, a context for empowerment and resistance of disablist attitudes, and an arena in which a sense of inclusion and belonging is experienced...
October 19, 2016: Disability and Rehabilitation
Philip M Massey, Ruth K Boansi, Jessica D Gipson, Rachel M Adams, Helene Riess, Thierno Dieng, Michael L Prelip, Deborah C Glik
OBJECTIVE: To examine HPV vaccine awareness and receptivity among adolescents and young adults in Senegal. METHODS: Participants from 6 high schools and 5 community centers across five regions of Senegal (n=2,286) completed a self-administered questionnaire in October and November 2014. The study assessed HPV awareness and receptivity toward receiving the HPV vaccine. Multivariable logistic regression explored statistically significant relationships between the predictor variables and both outcomes...
October 18, 2016: Tropical Medicine & International Health: TM & IH
Suzanne Oparil
Heart disease, stroke, and kidney failure are leading causes of death worldwide, and hypertension is a significant risk factor for each. Hypertension is less common in women, compared to men, in those younger than 45 years of age. This trend is reversed in those 65 years and older. In the US between 2011-2014, the prevalence of hypertension in women and men by age group was 6% vs 8% (18-39 years), 30% vs 35% (40-59 years), and 67% vs 63% (60 years and over). Awareness, treatment, and control rates differ between genders with women being more aware of their diagnosis (85% vs 80%), more likely to take their medications (81% vs 71%) and more frequently having controlled hypertension (55% vs 49%)...
September 2016: Journal of Hypertension
Harry Hx Wang, Jia Ji Wang, Kenny D Lawson, Samuel Ys Wong, Martin Cs Wong, Fang Jian Li, Pei Xi Wang, Zhi Heng Zhou, Yao Qun Yeong, Sian M Griffiths, Stewart W Mercer
OBJECTIVE: Multimorbidity (having ≥2 chronic conditions within an individual) is a rapidly increasing problem particularly among hypertensive patients. This study compared the prevalence of hypertension and those with multimorbidity in three study populations. DESIGN AND METHOD: We used cross-sectional data from three self-report surveys in China [N = 162,464], Scotland [N = 36,921], and Hong Kong [N = 29,187]. A consistent methodology was adopted to select representative samples of the household resident population of all ages by multi-stage stratified random sampling in each area...
September 2016: Journal of Hypertension
Keming Gao, Fang Fang, Zuowei Wang, Joseph R Calabrese
OBJECTIVES: To compare objective and subjective weight gain of second-generation antipsychotics in schizophrenia and bipolar disorder. METHODS: English-language literature published and cited in PubMed (MEDLINE) from January 1966 to December 2015 was searched with the keywords antipsychotic, atypical antipsychotic, or generic/brand name of atypical antipsychotics, and schizophrenia, bipolar disorder, bipolar mania, or bipolar depression, and safety, tolerability, weight gain, and randomized, placebo-controlled clinical trials...
October 5, 2016: Journal of Clinical Psychopharmacology
Rachel Lynn Wood, Stephen J Teach, Alexandra Rucker, Ambika Lall, James M Chamberlain, Leticia Manning Ryan
OBJECTIVES: Risk factors for residential fire death (young age, minority race/ethnicity, and low socioeconomic status) are common among urban pediatric emergency department (ED) patients. Community-based resources are available in our region to provide free smoke detector installation. The objective of our study was to describe awareness of these resources and home fire safety practices in this vulnerable population. METHODS: In this cross-sectional study, a brief survey was administered to a convenience sample of caregivers accompanying patients 19 years of age or younger in an urban pediatric ED in Washington, DC...
October 8, 2016: Pediatric Emergency Care
Sheng-Miauh Huang, Pei-Ling Hsieh, Yvonne Hsiung, Ling-Ming Tseng, Ping-Ho Chen, Chia Tai Hung
BACKGROUND: Previous studies indicate that women with cancer experience infertility after cancer-related treatment. With the rapid progress in fertility science, women face diverse and uncertain choices regarding pregnancy. OBJECTIVE: The aim of this study is to understand the decision-making process regarding fertility choices among reproductive-age women with cancer in Taiwan. METHODS: Grounded theory methodology guided data collection using in-depth interviews with 18 women diagnosed and treated for cancer...
October 6, 2016: Cancer Nursing
Matthias Oelke, Peter Anderson, Robert Wood, Tove Holm-Larsen
AIMS: The aim of this study was to investigate the quality and timing of the diagnosis and treatment of nocturia in real-life practice in European and US-American patients to obtain better insights into the management of nocturia in different Western healthcare systems. METHODS: Data were drawn from the "LUTS Disease Specific Programme," a real-life survey of physicians and patients in France, Germany, Spain, UK and the USA. Physicians completed a patient record form for lower urinary tract symptoms (LUTS) patients...
October 17, 2016: International Journal of Clinical Practice
Chris S Ivanoff, Krassimira Yaneva, Diana Luan, Bogomil Andonov, Reena R Kumar, Anirudha Agnihotry, Athena E Ivanoff, Dimitrios Emmanouil, Luiz Evaristo Ricci Volpato, Filip Koneski, Ilijana Muratovska, Huda A Al-Shehri, Sara M Al-Taweel, Michele Daly
BACKGROUND: Training culturally competent graduates who can practice effectively in a multicultural environment is a goal of contemporary dental education. The Global Oral Health Initiative is a network of dental schools seeking to promote global dentistry as a component of cultural competency training. OBJECTIVE: Before initiating international student exchanges, a survey was conducted to assess students' awareness of global dentistry and interest in cross-national clerkships...
October 18, 2016: International Dental Journal
Arham Zavery, Faisal Qureshi, Arbaz Riaz, Fatima Pervez, Nousheen Iqbal, Javaid A Khan
The aim of the study was to determine the prevalence of shisha smoking; its associated factors and awareness among medical students of Karachi, Pakistan following the imposition of nationwide shisha ban. A cross sectional study was conducted among medical students of two medical universities, namely Sindh Medical College and Aga Khan University Karachi, Pakistan from October till December 2014. A total of 422 participants were included. Data was collected via a self-administered questionnaire. The mean age was 21 ± 1...
October 17, 2016: Journal of Community Health
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