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https://www.readbyqxmd.com/read/28876656/colorectal-cancer-is-there-an-association-between-hiv-infection-and-the-clinicopathological-picture
#1
S K Pillay, Z Moolla, B Sartorius, T E Madiba
BACKGROUND: The link between colorectal cancer (CRC) and HIV has not been extensively studied. METHOD: Study setting: Colorectal unit at a tertiary institution. Study population: HIV negative and positive patients with colorectal cancer over 12 years (2005-2016). Study design: This is an analysis of prospectively collected data from a colorectal cancer database archived in the Gastrointestinal Cancer Research Centre, University of KwaZulu-Natal. Demographic details, HIV status, anatomical site, stage, treatment and follow-up were documented...
June 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28876564/oesophageal-squamous-cell-cancer-in-a-south-african-tertiary-hospital-a-risk-factor-and-presentation-analysis
#2
E Loots, B Sartorius, T E Madiba, C J J Mulder, D L Clarke
BACKGROUND: Squamous carcinoma of the oesophagus (SCO) is the most common form of oesophageal cancer in South Africa (SA). Risk factors include male gender, smoking, alcohol consumption and low socio-economic status (SES). This study assessed the risk factors for SCO in KwaZulu-Natal. METHOD: Information on patients managed at Inkosi Albert Luthuli Central Hospital (IALCH), Durban, South Africa, between 1 October 2013 and 31 December 2014 was retrieved from a prospective database of Oesophageal Cancer (OC)...
September 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28876563/defining-predictors-of-mortality-in-pediatric-trauma-patients
#3
P Brysiewicz, D L Clarke, B Sartorius, J L Bruce, G L Laing
BACKGROUND: The aim of this study was to describe our cohort of pediatric trauma patients and to analyze their physiological data. The intention was to highlight the difficulty in using systolic blood pressure (SBP) readings in this population and to investigate the role of base excess (BE) in predicting clinical outcomes in pediatric trauma patien. METHOD: The Pietermaritzburg Metropolitan Trauma Service (PMTS) maintains a prospective digital trauma registry, and all pediatric trauma patients admitted to the service for the period January 2012 - July 2016 were included...
September 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28866712/a-proposed-new-definition-of-mental-health
#4
REVIEW
Silvana Galderisi, Andreas Heinz, Marianne Kastrup, Julian Beezhold, Norman Sartorius
The authors propose a new approach to the definition of mental health, different than the definition proposed by the World Health Organization, which is established around issues of person's well-being and productivity. It is supposed to reflect the complexity of human life experience.
June 18, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/28859918/vital-sign-based-shock-scores-are-poor-at-triaging-south-african-trauma-patients
#5
Robert Barnes, Damian Clarke, Zane Farina, Benn Sartorius, Petra Brysiewicz, Grant Laing, John Bruce, Victor Kong
BACKGROUND: Traumatic shock cannot be diagnosed by a single physiological measurement and a number of vital sign based combined shock scores (CSS) have been proposed to identify and triage trauma patients with shock. This audit uses data from a prospectively entered electronic trauma registry to compare the ability of these CSS to predict in-hospital mortality, need for surgery, need for blood transfusion and ICU admission. MATERIALS AND METHODS: The data used in the study was obtained from the Hybrid Electronic Medical Record (HEMR) in Pietermaritzburg from January 2012-September 2015...
August 28, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28859843/anterior-subcutaneous-internal-fixation-of-the-pelvis-what-rod-to-bone-distance-is-anatomically-optimal
#6
Georg Osterhoff, Elisabeth V Aichner, Julian Scherer, Hans-Peter Simmen, Clément M L Werner, Georg C Feigl
INTRODUCTION: Anterior fixation of the pelvis using subcutaneous supra-acetabular pedicle screw internal fixation (INFIX) has proven to be a useful tool by avoiding the downsides of external fixation in patients where open fixation is not suited. The purpose of this study was to find a rod-to-bone distance for the INFIX that allows for minimal hazard to the inguinal neuro-vascular structures and, at the same time, as little as possible interference with the soft tissues of the proximal thigh when the patient is sitting...
August 25, 2017: Injury
https://www.readbyqxmd.com/read/28857260/reliability-and-validity-of-the-spanish-version-of-the-ideal-schedule-for-assessing-care-needs-in-dementia-cross-sectional-multicenter-study
#7
Raúl López-Antón, Juan Ramón Barrada, Javier Santabárbara, Mar Posadas-de Miguel, Luís Agüera, Carmen Burillo, Manuel Franco, Jorge López-Álvarez, Pilar Mesa, Roberto Petidier, Miguel Ángel Quintanilla, Bernabé Robles-Del Olmo, Tirso Ventura, Maya Semrau, Norman Sartorius, Antonio Lobo
OBJECTIVE: The IDEAL Schedule was developed for staging "care needs" in patients with dementia. We here aim to validate the Spanish version, further test its psychometric properties and explore a latent construct for "care needs". METHODS: A multicenter study was done in 8 dementia care facilities across Spain. Patients referred with a reliable ICD-10 diagnosis of dementia (n = 151) were assessed with the IDEAL Schedule by pairs of raters. Inter-rater reliability (intra-class correlation [ICC] coefficients), internal consistency (Cronbach's alpha), and factor analysis were calculated...
August 31, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28853585/the-effect-of-systematic-factors-on-the-outcome-of-trauma-laparotomy-at-a-major-trauma-centre-in-south-africa
#8
C Steenkamp, V Y Kong, D L Clarke, B Sartorius, J L Bruce, G L Laing, W Bekker, V Manchev, P Brysiewicz
Introduction The aim of this study was to examine and interrogate outcomes in trauma laparotomy in a South African trauma centre to determine whether systematic factors were associated with any discrepancies in outcome. Methods This was a retrospective review of a prospectively entered trauma registry undertaken at the Pietermaritzburg Metropolitan Trauma Service, Pietermaritzburg, South Africa. The service has developed a hybrid electronic medical record system (HEMR) where clinical data were captured in real time, which were incorporated this into a database...
September 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28837576/space-time-variations-in-child-mortality-in-a-rural-south-african-population-with-high-hiv-prevalence-2000-2014
#9
Boikhutso Tlou, Benn Sartorius, Frank Tanser
OBJECTIVE: The aim of the study was to identify the key determinants of child mortality 'hot-spots' in space and time. METHODS: Comprehensive population-based mortality data collected between 2000 and 2014 by the Africa Centre Demographic Information System located in the UMkhanyakude District of KwaZulu-Natal Province, South Africa, was analysed. We assigned all mortality events and person-time of observation for children <5 years of age to an exact homestead of residence (mapped to <2m accuracy as part of the DSA platform)...
2017: PloS One
https://www.readbyqxmd.com/read/28831085/percutaneous-closure-of-left-atrial-appendage-affects-mid-term-release-of-mr-proanp
#10
Michael Behnes, Benjamin Sartorius, Annika Wenke, Siegfried Lang, Ursula Hoffmann, Christian Fastner, Martin Borggrefe, Thomas Roth, Jakob Triebel, Thomas Bertsch, Ibrahim Akin
The left atrial appendage (LAA) represents both a predisposing source of thrombus formation and of neuro-humoral haemostasis. This study aims to evaluate changes of biomarker expression before and after successful percutaneous closure of the LAA. Patients with atrial fibrillation and contraindication for oral anticoagulant therapy were enrolled. Blood samples were taken within 24 hours before (T1) and at least 6 months (mid-term) (T2) after successful implantation of LAA occlusion devices. Blood levels of high sensitivity troponin I and T (hsTnI, hsTnT), aminoterminal pro-brain natriuretic peptide (NT-proBNP) and mid-regional pro-atrial natriuretic peptide (MR-proANP) were evaluated at both time points...
August 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28827055/prediction-of-muscle-strength-and-postoperative-function-after-knee-flexor-muscle-resection-for-soft-tissue-sarcoma-of-the-lower-limbs
#11
A Tanaka, Y Yoshimura, T Ishida, K Aoki, M Okamoto, M Kito, S Suzuki, A Takazawa, H Kato
INTRODUCTION: Oncological margins and prognosis are the most important factors for operative planning of soft tissue sarcomas, but prediction of postoperative function is also necessary. The purpose of this study was to predict the knee flexion strength and postoperative function after knee flexor muscle resection for soft tissue sarcoma of the lower limbs. MATERIALS AND METHODS: Seventeen patients underwent knee flexor muscle resection for soft tissue sarcoma of the lower limbs between 1991 and 2015...
August 4, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28825928/electroconvulsive-therapy-in-a-patient-with-ultrarapid-cycling-bipolar-disorder-a-case-report
#12
Laura Kranaster, Suna Su Aksay, Jan Malte Bumb, Christian Wisch, Michael Deuschle, Alexander Sartorius
No abstract text is available yet for this article.
August 18, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28809619/the-effect-of-hiv-status-on-clinical-outcomes-of-surgical-sepsis-in-kwazulu-natal-province-south-africa
#13
Samantha Green, Victor Y Kong, Jocinta Odendaal, Benn Sartorius, Damian L Clarke, Petra Brysiewicz, Jereme L Bruce, Grant L Laing, Wanda Bekker
BACKGROUND: KwaZulu-Natal Province, South Africa (SA), has long been the epicentre of the HIV epidemic, but the impact of HIV co-infection on the clinical outcomes of emergency surgical patients with sepsis remains largely unknown. OBJECTIVE: To review our experience with the management of patients with HIV co-infection and to compare the disease spectrum and outcome with those without HIV infection. METHODS: A retrospective study was undertaken at the Pietermaritzburg Metropolitan Surgical Service (PMSS), SA over a 5-year period from January 2010 to December 2014...
July 28, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28804634/muscle-mri-findings-in-a-one-year-old-girl-with-merosin-deficient-congenital-muscular-dystrophy-type-1a-due-to-lama2-mutation-a-case-report
#14
Yingyin Liang, Guidian Li, Songlin Chen, Rongxing He, Xiangxue Zhou, Yingming Chen, Xue Xu, Ronglan Zhu, Cheng Zhang
The objective of the present study was to characterize the muscle magnetic resonance imaging (MRI) features of a 1-year-old girl with merosin-deficient congenital muscular dystrophy type 1A (MDC1A). Beginning as an infant, this patient exhibited severe hypotonia and proximal weakness, as well as delays in developmental milestones. Her serum creatine kinase levels at 3 months, 8 months and 1 year were 2,959, 1,621 and 1,659 U/l, respectively. Brain MRI indicated symmetric, mild T1WI low, mild T2WI and FLAIR high radial patterns in the white matter of the Cornu posterius of the ventricular lateral...
August 2017: Biomedical Reports
https://www.readbyqxmd.com/read/28791439/metabolic-crosstalk-between-fatty-pancreas-and-fatty-liver-effects-on-local-inflammation-and-insulin-secretion
#15
Felicia Gerst, Robert Wagner, Gabriele Kaiser, Madhura Panse, Martin Heni, Jürgen Machann, Malte N Bongers, Tina Sartorius, Bence Sipos, Falko Fend, Christian Thiel, Silvio Nadalin, Alfred Königsrainer, Norbert Stefan, Andreas Fritsche, Hans-Ulrich Häring, Susanne Ullrich, Dorothea Siegel-Axel
AIMS/HYPOTHESIS: Obesity-linked ectopic fat accumulation is associated with the development of type 2 diabetes. Whether pancreatic and liver steatosis impairs insulin secretion is controversial. We examined the crosstalk of human pancreatic fat cells with islets and the role of diabetogenic factors, i.e. palmitate and fetuin-A, a hepatokine released from fatty liver. METHODS: Human pancreatic resections were immunohistochemically stained for insulin, glucagon, somatostatin and the macrophage/monocyte marker CD68...
August 8, 2017: Diabetologia
https://www.readbyqxmd.com/read/28790478/entrapment-neuropathy-of-the-infrapatellar-branch-of-the-saphenous-nerve-treated-by-partial-division-of-sartorius
#16
Gururaj Hosahalli, Adam Sierakowski, Hari Venkatramani, S Raja Sabapathy
We describe a case of entrapment neuropathy of the infrapatellar branch of the saphenous nerve as it pierces sartorius muscle. This is a rare cause of anteromedial knee pain that is easily overlooked and may be mistaken as arising from other anatomical structures in that region. The pain was successfully treated by partially dividing the sartorius muscle and translocating the nerve away from the site of entrapment. It is important to consider entrapment neuropathy of the infrapatellar branch of the saphenous nerve as a differential diagnosis when assessing a patient with anteromedial knee pain...
July 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28789998/does-hip-joint-positioning-affect-maximal-voluntary-contraction-in-the-gluteus-maximus-gluteus-medius-tensor-fasciaelatae-and-sartorius-muscles
#17
Jules Bernard, Julien Beldame, Stéphane Van Driessche, Helena Brunel, Thomas Poirier, Patrice Guiffault, Jean Matsoukis, Fabien Billuart
BACKGROUND: Minimally invasive total hip arthroplasty (THA) is presumed to provide functional and clinical benefits, whereas in fact the literature reveals that gait and posturographic parameters following THA do not recover values found in the general population. There is a significant disturbance of postural sway in THA patients, regardless of the surgical approach, although with some differences between approaches compared to controls: the anterior and anterolateral minimally invasive approaches seem to be more disruptive of postural parameters than the posterior approach...
August 5, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28768208/autobiographical-memory-deficits-in-patients-with-depression-follow-a-temporal-distribution
#18
Sarah V Biedermann, Traute Demirakca, Alexander Sartorius, Matthias K Auer, Gabriele Ende, Fabrice Berna
Autobiographical memory deficits are known in depression. The temporal distribution thereof across periods of life has rarely been considered yet. Autobiographical memories for 5 life periods were investigated in 27 depressed in-patients and compared to 31 matched healthy controls using the Bielefelder Autobiographisches Gedächtnis Inventar. Depressed patients reported significantly less details in memories dating from childhood to 30 years, correlating with severity of depression. Memories from childhood and recent periods were less positive in depressed patients...
July 26, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28765683/the-current-situations-and-needs-of-mental-health-in-china
#19
EDITORIAL
Norman Sartorius
No abstract text is available yet for this article.
April 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28761699/high-intensity-flywheel-exercise-and-recovery-of-atrophy-after-90-days-bed-rest
#20
Daniel L Belavý, Hiroshi Ohshima, Jörn Rittweger, Dieter Felsenberg
AIMS: To investigate differential muscle atrophy during bed-rest, the impact of a high-intensity concentric-eccentric (flywheel) resistance exercise countermeasure and muscle recovery after bed-rest. METHODS: Twenty-five healthy male subjects underwent 90 dayshead-down tilt bed-rest. Volume of individual lower-limb muscles was measured via MRI before, twice during and four times up to 1 year after bed-rest. Subjects were either inactive (n=16) or performed flywheel exercise every third day of bed-rest (n=9)...
2017: BMJ Open Sport & Exercise Medicine
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