keyword
MENU ▼
Read by QxMD icon Read
search

sartorius

keyword
https://www.readbyqxmd.com/read/29162035/reliability-and-validity-of-the-international-dementia-alliance-schedule-for-the-assessment-and-staging-of-care-in-china
#1
Xiao Wang, Zhenghai Sun, Lingchuan Xiong, Maya Semrau, Jianhua He, Yang Li, Jianzhong Zhu, Nan Zhang, Aimin Wang, Qinpu Jiang, Nan Mu, Yuping Zhao, Wei Chen, Donghui Wu, Zhanjie Zheng, Yongan Sun, Jing Zhang, Jun Xu, Xue Meng, Mei Zhao, Haifeng Zhang, Xiaozhen Lv, Norman Sartorius, Tao Li, Xin Yu, Huali Wang
BACKGROUND: Clinical and social services both are important for dementia care. The International Dementia Alliance (IDEAL) Schedule for the Assessment and Staging of Care was developed to guide clinical and social care for dementia. Our study aimed to assess the validity and reliability of the IDEAL schedule in China. METHODS: Two hundred eighty-two dementia patients and their caregivers were recruited from 15 hospitals in China. Each patient-caregiver dyad was assessed with the IDEAL schedule by a rater and an observer simultaneously...
November 21, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29154471/reducing-diastereomorphous-bis-phosphane-oxide-atropisomers-to-one-atropisomerically-pure-diphosphane-a-new-ligand-and-a-novel-ligand-preparation-design
#2
Frank Sartorius, Marc Trebing, Charlotte Brückner, Reinhard Brückner
1,1'-Biphenyl-2,2'-diphosphanes with an achiral bridge spanning C-5 and C-5' form atropisomers that are enantiomers. Accessing them in an atropisomerically pure form requires resolving a racemic mixture thereof or of a bis(phosphane oxide) precursor. 1,1'-Biphenyl-2,2'-diphosphanes with a homochiral bridge spanning C-5 and C-5' form atropisomers that are diastereomers. We synthesized the first compound of this kind 1) atropselectively and 2) under thermodynamic control-seemingly a first-time exploit in diphosphane synthesis...
November 20, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29137701/the-correlation-between-atls-and-junior-doctors-anatomical-knowledge-of-central-venous-catheter-insertion-at-a-major-trauma-service-in-south-africa
#3
V Y Kong, J J Odendaal, R Weale, M Liu, C M Keene, B Sartorius, D L Clarke
OBJECTIVE: To review the ability of junior doctors (JDs) in identifying the correct anatomical site for central venous catheterization (CVC) and whether prior Advanced Trauma Life Support (ATLS) training influences this. DESIGN: We performed a prospective, observational study using a structured survey and asked a group of JDs (postgraduate year 1 [PGY1] or year 2 [PGY2]) to indicate on a photograph the exact site for CVC insertion via the internal jugular (IJV) and the subclavian (SCV) approach...
November 7, 2017: Injury
https://www.readbyqxmd.com/read/29130482/longitudinal-observational-study-of-hidradenitis-suppurativa-impact-of-surgical-intervention-with-adjunctive-biologic-therapy
#4
Victoria K Shanmugam, Shaunak Mulani, Sean McNish, Sarah Harris, Teresa Buescher, Richard Amdur
BACKGROUND: Hidradenitis supppurativa (HS) is a chronic inflammatory disease of the apocrine sweat glands affecting 1-4% of the population. While surgical excision is a mainstay of therapy, lesions often recur. Biologic therapies, including tumor necrosis factor-α and IL-12/23 inhibitors, are effective for mild to moderate HS. However, longitudinal studies investigating biologic therapy in conjunction with surgery are limited. The purpose of this analysis was to investigate impact of surgery and biologic therapy on HS disease activity...
November 11, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/29117604/-in-depth-analysis-of-cost-structure-for-electroconvulsive-therapy-in-a-performance-based-hospital-budget
#5
Fritz-Georg Lehnhardt, Ines Dohle, Alexander Sartorius, Michael Grözinger
Objective New medical guideline recommendations for the treatment of major depressive disorders and regulative changes in the payment system of the German mental health care system warrant a revision of the framework in which electroconvulsive therapies (ECT) are offered. Methods A cost structure analysis of the clinical resources essential for the ECT procedure was conducted and economically validated, exemplified at a German inpatient ECT treatment center. Results The identification of directly attributable costs to the ECT intervention presupposes an accurate assessment of personnel engagement time and material consumption as well as an inclusion of overhead costs for the operational readiness of the hospital...
November 8, 2017: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/29098911/targeted-treatments-for-hidradenitis-suppurativa-a-review-of-the-current-literature-and-ongoing-clinical-trials
#6
Melody Maarouf, Ashley K Clark, Dylan E Lee, Vivian Y Shi
PURPOSE: Targeted, immune-modulating drugs are at the forefront of therapy for HS, and a comprehensive clinical trial registry is needed to facilitate data pooling and clinical efficacy comparison. MATERIALS AND METHODS: A systematic review of the ClinicalTrials.gov database was searched for planned, in-progress, completed, or terminated trials investigating the effect of targeted biologic therapies for hidradenitis suppurativa (HS). When results of RCTs were not available, case reports or series were included...
November 10, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29095275/muscle-ultrasound-a-useful-tool-in-newborn-screening-for-infantile-onset-pompe-disease
#7
Hsuen-En Hwang, Ting-Rong Hsu, Yueh-Hui Lee, Hsin-Kai Wang, Hong-Jen Chiou, Dau-Ming Niu
Our study aimed to evaluate the utility of muscle ultrasound in newborn screening of infantile-onset Pompe disease (IOPD) and to establish a system of severity grading. We retrospectively selected 35 patients with initial low acid alpha-glucosidase (GAA) activity and collected data including muscle ultrasound features, GAA gene mutation, activity/performance, and pathological and laboratory findings. The echogenicity of 6 muscles (the bilateral vastus intermedius, rectus femoris, and sartorius muscles) was compared to that of epimysium on ultrasound and rated either 1 (normal), 2 (mildly increased), or 3 (obviously increased)...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29092669/the-clinical-impact-of-a-positive-family-history-of-psychosis-or-mental-illness-in-psychotic-and-non-psychotic-mentally-ill-adolescents
#8
Saeeda Paruk, Khatija Jhazbhay, Keshika Singh, Benn Sartorius, Jonathan K Burns
BACKGROUND: A family history of psychosis is associated with negative clinical characteristics of psychosis. AIM: We aimed to determine the relationship between a family history (in first-degree relatives) of psychosis (FHP) or of any mental illness (FHM), and the clinical features (including cannabis use) of first episode early onset psychosis (EOP). METHOD: Forty-five adolescents with first episode EOP presenting to psychiatric services were assessed by clinical interview with the following tools: socio-demographic questionnaire, Positive and Negative Syndrome Scale (PANSS), Symptom Onset in Schizophrenia (SOS) inventory, and the World Health Organisation's (WHO) Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST) for cannabis misuse...
November 2, 2017: Journal of Child and Adolescent Mental Health
https://www.readbyqxmd.com/read/29064879/the-successful-implementation-of-a-modified-enhanced-recovery-after-surgery-eras-program-for-bariatric-surgery-in-a-south-african-teaching-hospital
#9
Emil Loots, Benn Sartorius, Imran M Paruk, Damian L Clarke
BACKGROUND: This study assessed the impact of strict adherence to perioperative pathways incorporating an enhanced recovery after surgery protocol on the outcomes of bariatric surgery at our center. METHODS: Prospective data were collected on 62 patients undergoing bariatric surgery between January 2011 and March 2016. Outcomes were compared between those who adhered to the perioperative pathway and those who did not. RESULTS: Fifty-three patients underwent laparoscopic sleeve gastrectomy, and 9 patients underwent Laparoscopic Roux-en-Y Gastric Bypass...
October 23, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/29063349/electroconvulsive-therapy-does-not-alter-the-synaptic-protein-neurogranin-in-the-cerebrospinal-fluid-of-patients-with-major-depression
#10
Laura Kranaster, Kaj Blennow, Henrik Zetterberg, Alexander Sartorius
Neurogranin (Ng) is a dendritic protein associated with synaptic plasticity, proposed to be a novel biomarker to measure synaptic dysfunction and degeneration in Alzheimer's disease. Since electroconvulsive therapy (ECT) has been suggested to facilitate neurogenesis and neural plasticity, we tested whether ECT could modify CSF Ng concentrations measured before and after a course of ECT in 12 patients with major depression. CSF Ng concentrations did not change, but baseline levels were positively correlated with the therapeutic response...
December 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29060803/analysis-of-muscle-activation-in-lower-extremity-for-static-balance
#11
Kingshuk Chakravarty, Debatri Chatterjee, Rajat Kumar Das, Soumya Ranjan Tripathy, Aniruddha Sinha
Balance plays an important role for human bipedal locomotion. Degeneration of balance control is prominent in stroke patients, elderly adults and even for majority of obese people. Design of personalized balance training program, in order to strengthen muscles, requires the analysis of muscle activation during an activity. In this paper we have proposed an affordable and portable approach to analyze the relationship between the static balance strategy and activation of various lower extremity muscles. To do that we have considered Microsoft Kinect XBox 360 as a motion sensing device and Wii balance board for measuring external force information...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29048929/the-effect-of-hamstring-tendon-autograft-harvest-on-the-restoration-of-knee-stability-in-the-setting-of-concurrent-anterior-cruciate-ligament-and-medial-collateral-ligament-injuries
#12
Thomas J Kremen, Landon S Polakof, Sean S Rajaee, Trevor J Nelson, Melodie F Metzger
BACKGROUND: A hamstring autograft is commonly used in anterior cruciate ligament (ACL) reconstruction (ACLR); however, there is evidence to suggest that the tendons harvested may contribute to medial knee instability. HYPOTHESIS: We tested the hypothesis that the gracilis (G) and semitendinosus (ST) tendons significantly contribute to sagittal, coronal, and/or rotational knee stability in the setting of ACLR with a concurrent partial medial collateral ligament (MCL) injury...
October 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29041730/multi-pass-cell-based-nonlinear-pulse-compression-to-115-fs-at-7-5-%C3%A2%C2%B5j-pulse-energy-and-300-w-average-power
#13
Johannes Weitenberg, Andreas Vernaleken, Jan Schulte, Akira Ozawa, Thomas Sartorius, Vladimir Pervak, Hans-Dieter Hoffmann, Thomas Udem, Peter Russbüldt, Theodor W Hänsch
We demonstrate nonlinear pulse compression by multi-pass cell spectral broadening (MPCSB) from 860 fs to 115 fs with compressed pulse energy of 7.5 µJ, average power of 300 W and close to diffraction-limited beam quality. The transmission of the compression unit is >90%. The results show that this recently introduced compression scheme for peak powers above the threshold for catastrophic self-focusing can be scaled to smaller pulse energies and can achieve a larger compression factor than previously reported...
August 21, 2017: Optics Express
https://www.readbyqxmd.com/read/29031729/point-mutation-of-ffar1-abrogates-fatty-acid-dependent-insulin-secretion-but-protects-against-hfd-induced-glucose-intolerance
#14
Sibylle Sabrautzki, Gabriele Kaiser, Gerhard K H Przemeck, Felicia Gerst, Estela Lorza-Gil, Madhura Panse, Tina Sartorius, Miriam Hoene, Susan Marschall, Hans-Ulrich Häring, Martin Hrabě de Angelis, Susanne Ullrich
OBJECTIVE: The fatty acid receptor 1 (FFAR1/GPR40) mediates fatty acid-dependent augmentation of glucose-induced insulin secretion (GIIS) in pancreatic β-cells. Genetically engineered Ffar1-knockout/congenic mice univocally displayed impaired fatty acid-mediated insulin secretion, but in vivo experiments delivered controversial results regarding the function of FFAR1 in glucose homeostasis and liver steatosis. This study presents a new coisogenic mouse model carrying a point mutation in Ffar1 with functional consequence...
October 2017: Molecular Metabolism
https://www.readbyqxmd.com/read/29025454/an-audit-of-traumatic-brain-injury-tbi-in-a-busy-developing-world-trauma-service-exposes-a-significant-deficit-in-resources-available-to-manage-severe-tbi
#15
Ellen Jerome, Grant L Laing, John L Bruce, Ben Sartorius, Petra Brysiewicz, Damian L Clarke
BACKGROUND: Traumatic brain injury (TBI) affects large numbers of patients, both adults and children, and significant resources are needed to manage it. OBJECTIVE: To determine the burden of TBI and the adequacy of available resources to manage in the Pietermaritzburg Metropolitan Trauma Service (PMTS). METHODS: All patients with a TBI were identified from the hybrid electronic medical registry at Grey's and Edendale hospitals in Pietermaritzburg (PMB), KwaZulu-Natal, South Africa...
June 30, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29025449/incidence-of-chemotherapy-induced-neutropenia-in-hiv-infected-and-uninfected-patients-with-breast-cancer-receiving-neoadjuvant-chemotherapy
#16
Sithembile Ngidi, Nombulelo Magula, Ben Sartorius, Pooven Govender, Thandinkosi E Madiba
BACKGROUND: Chemotherapy-induced neutropenia (CIN) can result in poor tolerance of chemotherapy, leading to dose reductions, delays in therapy schedules, morbidity and mortality. Actively identifying predisposing risk factors before treatment is of paramount importance. We hypothesised that chemotherapy is associated with a greater increase in CIN and its complications in HIV-infected patients than in those who are not infected. OBJECTIVE: To establish the incidence of CIN in HIV-infected and uninfected patients undergoing chemotherapy...
June 30, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29022788/developing-a-simplified-clinical-prediction-score-for-mortality-in-patients-with-cerebral-gunshot-wounds-the-maritzburg-score
#17
V Y Kong, J Odendaal, B Sartorius, D L Clarke, J L Bruce, G L Laing, T Esterhuizen
Introduction Cerebral gunshot wounds are highly lethal and literature on the clinical scores for mortality prediction is limited. Materials and methods A retrospective study was undertaken over a 5-year period at the Pietermaritzburg Metropolitan Trauma Service in South Africa. A simplified clinical prediction score was developed based on clinical and/or physiological variables readily available in the resuscitation room. Results A total of 102 patients were included; 92% (94/102) were male and the mean age was 29 years; 22% (22/102) died during the admission...
September 15, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29019978/the-prevalence-of-plasmodium-falciparum-in-sub-saharan-africa-since-1900
#18
Robert W Snow, Benn Sartorius, David Kyalo, Joseph Maina, Punam Amratia, Clara W Mundia, Philip Bejon, Abdisalan M Noor
Malaria transmission is influenced by climate, land use and deliberate interventions. Recent declines have been observed in malaria transmission. Here we show that the African continent has witnessed a long-term decline in the prevalence of Plasmodium falciparum from 40% prevalence in the period 1900-1929 to 24% prevalence in the period 2010-2015, a trend that has been interrupted by periods of rapidly increasing or decreasing transmission. The cycles and trend over the past 115 years are inconsistent with explanations in terms of climate or deliberate intervention alone...
October 26, 2017: Nature
https://www.readbyqxmd.com/read/28983961/developing-a-predictive-model-for-fine-particulate-matter-concentrations-in-low-socio-economic-households-in-durban-south-africa
#19
B Shezi, N Jafta, B Sartorius, R N Naidoo
In low-resource settings, there is a need to develop models that can address contributions of household and outdoor sources to population exposures. The aim of the study was to model indoor PM2.5 using household characteristics, activities, and outdoor sources. Households belonging to participants in the Mother and Child in the Environment (MACE) birth cohort, in Durban, South Africa, were randomly selected. A structured walk-through identified variables likely to generate PM2.5 . MiniVol samplers were used to monitor PM2...
October 6, 2017: Indoor Air
https://www.readbyqxmd.com/read/28983565/the-burden-of-primary-liver-cancer-and-underlying-etiologies-from-1990-to-2015-at-the-global-regional-and-national-level-results-from-the-global-burden-of-disease-study-2015
#20
Tomi Akinyemiju, Semaw Abera, Muktar Ahmed, Noore Alam, Mulubirhan Assefa Alemayohu, Christine Allen, Rajaa Al-Raddadi, Nelson Alvis-Guzman, Yaw Amoako, Al Artaman, Tadesse Awoke Ayele, Aleksandra Barac, Isabela Bensenor, Adugnaw Berhane, Zulfiqar Bhutta, Jacqueline Castillo-Rivas, Abdulaal Chitheer, Jee-Young Choi, Benjamin Cowie, Lalit Dandona, Rakhi Dandona, Subhojit Dey, Daniel Dicker, Huyen Phuc, Donatus U Ekwueme, Maysaa El Sayed Zaki, Florian Fischer, Thomas Fürst, Jamie Hancock, Simon I Hay, Peter Hotez, Sun Ha Jee, Amir Kasaeian, Yousef Khader, Young-Ho Khang, G Anil Kumar, Michael Kutz, Heidi Larson, Alan Lopez, Raimundas Lunevicius, Reza Malekzadeh, Colm McAlinden, Toni Meier, Walter Mendoza, Ali Mokdad, Maziar Moradi-Lakeh, Gabriele Nagel, Quyen Nguyen, Grant Nguyen, Felix Ogbo, George Patton, David M Pereira, Farshad Pourmalek, Mostafa Qorbani, Amir Radfar, Gholamreza Roshandel, Joshua A Salomon, Juan Sanabria, Benn Sartorius, Maheswar Satpathy, Monika Sawhney, Sadaf Sepanlou, Katya Shackelford, Hirbo Shore, Jiandong Sun, Desalegn Tadese Mengistu, Roman Topór-Madry, Bach Tran, Kingsley Nnanna Ukwaja, Vasiliy Vlassov, Stein Emil Vollset, Theo Vos, Tolassa Wakayo, Elisabete Weiderpass, Andrea Werdecker, Naohiro Yonemoto, Mustafa Younis, Chuanhua Yu, Zoubida Zaidi, Liguo Zhu, Christopher J L Murray, Mohsen Naghavi, Christina Fitzmaurice
Importance: Liver cancer is among the leading causes of cancer deaths globally. The most common causes for liver cancer include hepatitis B virus (HBV) and hepatitis C virus (HCV) infection and alcohol use. Objective: To report results of the Global Burden of Disease (GBD) 2015 study on primary liver cancer incidence, mortality, and disability-adjusted life-years (DALYs) for 195 countries or territories from 1990 to 2015, and present global, regional, and national estimates on the burden of liver cancer attributable to HBV, HCV, alcohol, and an "other" group that encompasses residual causes...
October 5, 2017: JAMA Oncology
keyword
keyword
87419
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"