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https://www.readbyqxmd.com/read/28227990/using-computational-phantoms-to-improve-delivery-of-tumor-treating-fields-ttfields-to-patients
#1
Ze'ev Bomzon, Hadas Sara Hershkovich, Noa Urman, Aafia Chaudhry, Dario Garcia-Carracedo, Anders R Korshoej, Uri Weinberg, Cornelia Wenger, Pedro Miranda, Yoram Wasserman, Eilon D Kirson, Yoram, Ze'ev Bomzon, Hadas Sara Hershkovich, Noa Urman, Aafia Chaudhry, Dario Garcia-Carracedo, Anders R Korshoej, Uri Weinberg, Cornelia Wenger, Pedro Miranda, Yoram Wasserman, Eilon D Kirson, Yoram, Uri Weinberg, Cornelia Wenger, Noa Urman, Hadas Sara Hershkovich, Yoram Wasserman, Anders R Korshoej, Eilon D Kirson, Dario Garcia-Carracedo, Pedro Miranda, Aafia Chaudhry, Zeev Bomzon, Yoram
This paper reviews the state-of-the-art in simulation-based studies of Tumor Treating Fields (TTFields) and highlights major aspects of TTFields in which simulation-based studies could affect clinical outcomes. A major challenge is how to simulate multiple scenarios rapidly for TTFields delivery. Overcoming this challenge will enable a better understanding of how TTFields distribution is correlated with disease progression, leading to better transducer array designs and field optimization procedures, ultimately improving patient outcomes...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227982/analysis-of-the-sleep-eeg-in-the-complexity-domain
#2
Sara Mariani, Ana F T Borges, Teresa Henriques, Robert J Thomas, Samuel J Leistedt, Paul Linkowski, Jean-Pol Lanquart, Ary L Goldberger, Madalena D Costa, Sara Mariani, Ana F T Borges, Teresa Henriques, Robert J Thomas, Samuel J Leistedt, Paul Linkowski, Jean-Pol Lanquart, Ary L Goldberger, Madalena D Costa, Teresa Henriques, Robert J Thomas, Madalena D Costa, Samuel J Leistedt, Paul Linkowski, Ary L Goldberger, Jean-Pol Lanquart, Sara Mariani, Ana F T Borges
Conventional sleep analysis relies primarily on electroencephalogram (EEG) waveform features assessed in concert with eye movements, respiration and muscle tone. We explore a complementary "complexity domain" approach based on multiscale entropy (MSE) analysis of EEG signals and discuss its relationships to standard sleep analysis and to that based on electrocardiogram (ECG)-derived cardiopulmonary coupling (CPC). We observe a progressive decrease in complexity associated with decreased arousability, as measured by both conventional sleep scoring and CPC analysis...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227704/comparing-glucose-and-insulin-data-from-the-two-hour-oral-glucose-tolerance-test-in-metabolic-syndrome-subjects-and-marathon-runners
#3
Miguel Altuve, Gilberto Perpinan, Erika Severeyn, Sara Wong, Miguel Altuve, Gilberto Perpinan, Erika Severeyn, Sara Wong, Sara Wong, Gilberto Perpinan, Erika Severeyn
Glucose is the main energy source of the body's cells and is essential for normal metabolism. Two pancreatic hormones, insulin and glucagon, are involved in glucose home-ostasis. Alteration in the plasma glucose and insulin concentrations could lead to distinct symptoms and diseases, ranging from mental function impairment to coma and even death. Type 2 diabetes, insulin resistance and metabolic syndrome are typical examples of abnormal glucose metabolism that increase the risk for cardiovascular disease and mortality...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227540/a-preliminary-study-for-quantitative-assessment-of-upper-limb-proprioception
#4
Sara Contu, Asif Hussain, Lorenzo Masia, Domenico Campolo, Sara Contu, Asif Hussain, Lorenzo Masia, Domenico Campolo, Asif Hussain, Lorenzo Masia, Sara Contu, Domenico Campolo
Proprioception, or sense of position and movement of the body, strongly correlates with motor recovery of the hemiplegic arm. The evaluation of the awareness of the location of joints in space involves measuring the accuracy of joint-angle replication. Robotic devices allow an accurate manipulation of joint movements necessary to assess proprioceptive status. This study evaluated the proprioceptive performance of healthy subjects by mean of the H-Man, a planar robot designed for upper-limb rehabilitation to gather preliminary normative data for neurorehabilitation applications...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227539/robot-assisted-assessment-of-wrist-proprioception-does-wrist-proprioceptive-acuity-follow-weber-s-law
#5
Sara Contu, Francesca Marini, Leonardo Cappello, Lorenzo Masia, Sara Contu, Francesca Marini, Leonardo Cappello, Lorenzo Masia, Lorenzo Masia, Sara Contu, Leonardo Cappello, Francesca Marini
Proprioception is essential for planning and controlling limb posture and movement. In our recent work, we introduced a standardized robot-aided method for measuring proprioceptive discrimination thresholds at the wrist to obtain reliable and accurate measures of proprioceptive acuity. Weber's law defines discrimination thresholds as a constant ratio between the just noticeable difference and the reference or standard stimulus. Reporting Weber's fractions thus provides the possibility of comparing results with the reports of others collected worldwide...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227457/evaluation-of-periodic-breathing-in-respiratory-flow-signal-of-elderly-patients-using-svm-and-linear-discriminant-analysis
#6
Sara Argerich, Sergio Herrera, Salvador Benito, Beatriz F Giraldo, Sara Argerich, Sergio Herrera, Salvador Benito, Beatriz F Giraldo, Beatriz F Giraldo, Salvador Benito, Sara Argerich, Sergio Herrera
Aging population is a major concern that is reflected in the increase of chronic diseases. Heart Failure (HF) is one of the most common chronic diseases of elderly people that is punctuated with acute episodes, which result in hospitalization. The periodic modulation of the amplitude of the breathing pattern is proved to be one of the multiple symptoms of an acute episode, and thus, the features extracted from its characterization contribute in the improvement of the first diagnosis of the clinical practice...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227234/computational-human-model-vhp-female-derived-from-datasets-of-the-national-library-of-medicine
#7
Gregory M Noetscher, Janakinadh Yanamadala, Harshal Tankaria, Sara Louie, Alexander Prokop, Ara Nazarian, Sergey N Makarov, Gregory M Noetscher, Janakinadh Yanamadala, Harshal Tankaria, Sara Louie, Alexander Prokop, Ara Nazarian, Sergey N Makarov, Ara Nazarian, Janakinadh Yanamadala, Gregory M Noetscher, Sergey N Makarov, Alexander Prokop, Harshal Tankaria, Sara Louie
Simulation of the electromagnetic response of the human body relies upon efficient computational models. The objective of this paper is to describe a new platform-independent and computationally-efficient full-body electromagnetic model, the Visible Human Project® (VHP)-Female v.3.0 and to outline its distinct features. We also report model performance results using two leading commercial electromagnetic antenna simulation packages: ANSYS HFSS and CST MICROWAVE STUDIO®.
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226993/first-steps-to-creating-a-platform-for-high-throughput-simulation-of-ttfields
#8
Hadas Sara Hershkovich, Zeev Bomzon, Cornelia Wenger, Noa Urman, Aafia Chaudhry, Dario Garcia-Carracedo, Eilon D Kirson, Uri Weinberg, Yoram Wassermann, Yoram Palti, Hadas Sara Hershkovich, Zeev Bomzon, Cornelia Wenger, Noa Urman, Aafia Chaudhry, Dario Garcia-Carracedo, Eilon D Kirson, Uri Weinberg, Yoram Wassermann, Yoram Palti, Yoram Wassermann, Cornelia Wenger, Uri Weinberg, Hadas Sara Hershkovich, Zeev Bomzon, Eilon D Kirson, Dario Garcia-Carracedo, Yoram Palti, Noa Urman, Aafia Chaudhry
Tumor Treating Fields (TTFields) are low intensity alternating electric fields in the 100-500 KHz frequency range that are known to have an anti-mitotic effect on cancerous cells. In the USA, TTFields are approved by the Food and Drug Administration (FDA) for the treatment of glioblastoma (GBM) in both the newly diagnosed and recurrent settings. Optimizing treatment with TTFields requires a deep understanding of how TTFields distribute within the brain. To address this issue, simulations using realistic head models have been performed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226964/vhp-female-full-body-human-cad-model-for-cross-platform-fem-simulations-recent-development-and-validations
#9
Harshal Tankaria, Xavier J Jackson, Raunak Borwankar, Goutham N K Srichandhru, Anh Le Tran, Janakinadh Yanamadala, Gregory M Noetscher, Ara Nazarian, Sara Louie, Sergey N Makarov, Harshal Tankaria, Xavier J Jackson, Raunak Borwankar, Goutham N K Srichandhru, Anh Le Tran, Janakinadh Yanamadala, Gregory M Noetscher, Ara Nazarian, Sara Louie, Sergey N Makarov, Janakinadh Yanamadala, Gregory M Noetscher, Anh Le Tran, Sergey N Makarov, Sara Louie, Ara Nazarian, Goutham N K Srichandhru, Xavier J Jackson, Harshal Tankaria, Raunak Borwankar
Simulation of the electromagnetic response of the human body relies heavily upon efficient computational models or phantoms. The first objective of this paper is to present an improved platform-independent full-body electromagnetic computational model (computational phantom), the Visible Human Project® (VHP)-Female v. 3.1 and to describe its distinct features and enhancements compared to VHP-Female v. 2.0. The second objective is to report phantom simulation for electric stimulation studies using the commercial FEM electromagnetic solver ANSYS MAXWELL...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226713/automatic-workflow-for-narrow-band-laryngeal-video-stitching
#10
Sara Moccia, Veronica Penza, Gabriele Omodeo Vanone, Elena De Momi, Leonardo S Mattos, Sara Moccia, Veronica Penza, Gabriele Omodeo Vanone, Elena De Momi, Leonardo S Mattos, Elena De Momi, Leonardo S Mattos, Gabriele Omodeo Vanone, Veronica Penza, Sara Moccia
In narrow band (NB) laryngeal endoscopy, the clinician usually positions the endoscope near the tissue for a correct inspection of possible vascular pattern alterations, indicative of laryngeal malignancies. The video is usually reviewed many times to refine the diagnosis, resulting in loss of time since the salient frames of the video are mixed with blurred, noisy, and redundant frames caused by the endoscope movements. The aim of this work is to provide to the clinician a unique larynx panorama, obtained through an automatic frame selection strategy to discard non-informative frames...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226674/a-multiple-kernel-learning-approach-for-human-behavioral-task-classification-using-stn-lfp-signal
#11
Hosein M Golshan, Adam O Hebb, Sara J Hanrahan, Joshua Nedrud, Mohammad H Mahoor, Hosein M Golshan, Adam O Hebb, Sara J Hanrahan, Joshua Nedrud, Mohammad H Mahoor, Joshua Nedrud, Adam O Hebb, Sara J Hanrahan, Mohammad H Mahoor, Hosein M Golshan
Deep Brain Stimulation (DBS) has gained increasing attention as an effective method to mitigate Parkinson's disease (PD) disorders. Existing DBS systems are open-loop such that the system parameters are not adjusted automatically based on patient's behavior. Classification of human behavior is an important step in the design of the next generation of DBS systems that are closed-loop. This paper presents a classification approach to recognize such behavioral tasks using the subthalamic nucleus (STN) Local Field Potential (LFP) signals...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226661/optimal-weighted-averaging-of-event-related-activity-from-acquisitions-with-artifacts
#12
Luca Vollero, Sara Petrichella, Giulio Innello, Luca Vollero, Sara Petrichella, Giulio Innello, Luca Vollero, Sara Petrichella, Giulio Innello
In several biomedical applications that require the signal processing of biological data, the starting procedure for noise reduction is the ensemble averaging of multiple repeated acquisitions (trials). This method is based on the assumption that each trial is composed of two additive components: (i) a time-locked activity related to some sensitive/stimulation phenomenon (ERA, Event Related Activity in the following) and (ii) a sum of several other non time-locked background activities. The averaging aims at estimating the ERA activity under very low Signal to Noise and Interference Ratio (SNIR)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226592/characterizing-artifacts-in-rr-stress-test-time-series
#13
Fabian Astudillo-Salinas, Kenneth Palacio-Baus, Lizandro Solano-Quinde, Ruben Medina, Sara Wong, Fabian Astudillo-Salinas, Kenneth Palacio-Baus, Lizandro Solano-Quinde, Ruben Medina, Sara Wong, Kenneth Palacio-Baus, Sara Wong, Fabian Astudillo-Salinas, Lizandro Solano-Quinde, Ruben Medina
Electrocardiographic stress test records have a lot of artifacts. In this paper we explore a simple method to characterize the amount of artifacts present in unprocessed RR stress test time series. Four time series classes were defined: Very good lead, Good lead, Low quality lead and Useless lead. 65 ECG, 8 lead, records of stress test series were analyzed. Firstly, RR-time series were annotated by two experts. The automatic methodology is based on dividing the RR-time series in non-overlapping windows. Each window is marked as noisy whenever it exceeds an established standard deviation threshold (SDT)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226259/synthesis-optimization-of-oil-palm-empty-fruit-bunch-and-rice-husk-biochars-for-removal-of-imazapic-and-imazapyr-herbicides
#14
Saba Yavari, Amirhossein Malakahmad, Nasiman B Sapari, Sara Yavari
Imidazolinones are a family of herbicides that are used to control a broad range of weeds. Their high persistence and leaching potential make them probable risk to the ecosystems. In this study, biochar, the biomass-derived solid material, was produced from oil palm empty fruit bunches (EFB) and rice husk (RH) through pyrolysis process. Feedstock and pyrolysis variables can control biochar sorption capacity. Therefore, the present study attempts to evaluate effects of three pyrolysis variables (temperature, heating rate and retention time) on abilities of biochars for removal of imazapic and imazapyr herbicides from soil...
February 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28226237/novel-insights-into-tree-biology-and-genome-evolution-as-revealed-through-genomics
#15
David B Neale, Pedro J Martínez-García, Amanda R De La Torre, Sara Montanari, Xiao-Xin Wei
Reference genome sequences are the key to the discovery of genes and gene families that determine traits of interest. Recent progress in sequencing technologies has enabled a rapid increase in genome sequencing of tree species, allowing the dissection of complex characters of economic importance, such as fruit and wood quality and resistance to biotic and abiotic stresses. Although the number of reference genome sequences for trees lags behind those for other plant species, it is not too early to gain insight into the unique features that distinguish trees from nontree plants...
February 6, 2017: Annual Review of Plant Biology
https://www.readbyqxmd.com/read/28225616/a-straightforward-approach-for-3d-bacterial-printing
#16
Benjamin A E Lehner, Dominik T Schmieden, Anne Sara Meyer
Sustainable and personally tailored materials production is an emerging challenge to society. Living organisms can produce and pattern an extraordinarily wide range of different molecules in a sustainable way. These natural systems offer an abundant source of inspiration for the development of new environmentally-friendly materials production techniques. In this paper, we describe the first steps towards the 3-dimensional printing of bacterial cultures for materials production and patterning. This methodology combines the capability of bacteria to form new materials with the reproducibility and tailored approach of 3D printing systems...
February 22, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28225462/validity-evidence-from-ratings-of-pediatric-interns-and-subinterns-on-a-subset-of-pediatric-milestones
#17
Teri L Turner, Vasudha L Bhavaraju, Ulana A Luciw-Dubas, Patricia J Hicks, Sara Multerer, Amanda Osta, Jennifer McDonnell, Sue Poynter, Daniel J Schumacher, Rebecca Tenney-Soeiro, Linda Waggoner-Fountain, Alan Schwartz
PURPOSE: To investigate evidence for validity of faculty members' pediatric milestone (PM) ratings of interns (first-year residents) and subinterns (fourth-year medical students) on nine subcompetencies related to readiness to serve as a pediatric intern in the inpatient setting. METHOD: The Association of Pediatric Program Directors Longitudinal Educational Assessment Research Network (APPD LEARN) and the National Board of Medical Examiners collaborated to investigate the utility of assessments of the PMs for trainees' performance...
February 21, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28225100/hybrid-plasmonic-photonic-whispering-gallery-mode-resonators-for-sensing-a-critical-review
#18
REVIEW
Angelo Bozzola, Sara Perotto, Francesco De Angelis
In this review we present the state of the art and the most recent advances in the field of optical sensing with hybrid plasmonic-photonic whispering gallery mode (WGM) resonators. After a brief introduction on the basic physics behind photonic WGM resonators and localized surface plasmon (LSP) nanostructures, we analyze the different types of optical sensors specifically designed for bulk refractive index sensing, molecular binding and single object detection. We point out the physical and technological key points of the different approaches proposed in the literature, and we systematically compare hybrid sensors and purely photonic WGM sensors...
February 22, 2017: Analyst
https://www.readbyqxmd.com/read/28224727/molecular-identification-and-distribution-of-non-tuberculous-mycobacteria-isolated-from-clinical-specimens-by-pcr-sequencing-method-in-west-of-iran
#19
Mahsa Dastranj, Abbas Farahani, Abdolrazagh Hashemi Shahraki, Sara Atashi, Parviz Mohajeri
BACKGROUND AND AIMS: Infections by Non-tuberculous Mycobacteria (NTM) has rapidly increased in recent years, due to high infection rates related to the populations at risk like immunocompromised individuals, patients predisposed by prior pulmonary. The aim of this study was to investigate the presence of NTM in clinical samples and genetic diversity using 16S rRNA and rpoB sequence analysis. METHODS: A cross-sectional study was conducted on 45 diverse isolates collected from sputum in two years 2014-2015 using standard decontamination procedure...
February 22, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28224270/intrapartal-pelvic-floor-protection-a-pragmatic-and-interdisciplinary-approach-between-obstetrics-and-urogynecology
#20
Markus Huebner, Sara Y Brucker, Ralf Tunn, Gert Naumann, Christl Reisenauer, Harald Abele
Pelvic floor protection is an issue of increasing relevance. This article sought to summarize the session at last year's annual meeting of the German Society of Gynecology and Obstetrics (DGGG) in Stuttgart (10/2016) called "Urogynecology 2020-what is the optimal rate of cesarean section-does urogynecology have to deal with Obstetrics?". The main focus was set on the two important anatomical structures, the levator ani muscle and the anal sphincters. Operative vaginal delivery, epidural anesthesia, and episiotomy are subject to discussion...
February 21, 2017: Archives of Gynecology and Obstetrics
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