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https://www.readbyqxmd.com/read/29136026/operative-technique-at-caesarean-delivery-and-risk-of-complete-uterine-rupture-in-a-subsequent-trial-of-labour-at-term-a-registry-case-control-study
#1
Dorthe L A Thisted, Laust H Mortensen, Lone Hvidman, Lone Krebs
OBJECTIVE: To estimate the relation of single-layer closure at previous caesarean delivery, and other pre-labour and intra-partum risk factors for complete uterine rupture in trial of vaginal birth after a caesarean (TOLAC) at term. STUDY DESIGN: Population-based case-control study. We identified all women (n = 39 742) recorded in the Danish Medical Birth Registry (DMBR) during a 12-year period (1997-2008) with a singleton pregnancy at term and TOLAC. Among these, all women with a complete uterine rupture were identified (cases)...
2017: PloS One
https://www.readbyqxmd.com/read/29129793/the-interval-between-vns-tone-pairings-determines-the-extent-of-cortical-map-plasticity
#2
Michael S Borland, Crystal T Engineer, William A Vrana, Nicole A Moreno, Navzer D Engineer, Sven Vanneste, Pryanka Sharma, Meghan C Pantalia, Mark C Lane, Robert L Rennaker, Michael P Kilgard
Repeatedly pairing vagus nerve stimulation (VNS) with a tone or movement drives highly-specific and long-lasting plasticity in auditory or motor cortex, respectively. Based on this robust enhancement of plasticity, VNS paired with rehabilitative training has emerged as a potential therapy to improve recovery, even when delivered long after the neurological insult. Development of VNS delivery paradigms that reduce therapy duration and maximize efficacy would facilitate clinical translation. The goal of the current study was to determine whether primary auditory cortex (A1) plasticity can be generated more quickly by shortening the interval between VNS-tone pairing events or by delivering fewer VNS-tone pairing events...
November 9, 2017: Neuroscience
https://www.readbyqxmd.com/read/29128586/contraception-pregnancy-and-peripartum-experiences-among-women-with-epilepsy-in-bhutan
#3
Sheliza Halani, Lhab Tshering, Esther Bui, Sarah J Clark, Sara J Grundy, Tandin Pem, Sonam Lhamo, Ugyen Dema, Damber K Nirola, Chencho Dorji, Farrah J Mateen
INTRODUCTION: Reports on the reproductive health of women with epilepsy (WWE) in low- and middle-income countries (LMICs) are limited. Bhutan is a lower income country with a high estimated prevalence of epilepsy and no out-of-pocket payment requirements for health visits or medications. METHODS: We developed a 10-category survey to interview WWE ages 20-59 years in the Kingdom of Bhutan to understand their contraceptive use and peripartum experiences. WWE were recruited from 2016-2017 from an existing epilepsy cohort and their reproductive health data were merged with epilepsy and socioeconomic data obtained from initial clinical evaluations performed between 2014 and 2016...
December 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29102186/maternal-urinary-carbofuranphenol-levels-before-delivery-and-birth-outcomes-in-sheyang-birth-cohort
#4
Jiming Zhang, Jianqiu Guo, Dasheng Lu, Xiaojuan Qi, Xiuli Chang, Chunhua Wu, Yubin Zhang, Weijiu Liang, Xin Fang, Yang Cao, Zhijun Zhou
Exposure to carbamates has been linked with adverse health effects on developmental period. This study aimed to monitor exposure to carbofuranphenol of pregnant women from Sheyang Birth Cohort and investigate associations between prenatal exposure to carbofuranphenol and birth outcomes. During June 2009 to January 2010, 1100 pregnant women living in Sheyang County participated in our study and donated urine sample. Urinary carbofuranphenol concentration was measured by gas chromatography-tandem mass spectrometry...
October 25, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29095502/obstetric-outcomes-after-conservative-treatment-for-cervical-intraepithelial-lesions-and-early-invasive-disease
#5
REVIEW
Maria Kyrgiou, Antonios Athanasiou, Ilkka E J Kalliala, Maria Paraskevaidi, Anita Mitra, Pierre Pl Martin-Hirsch, Marc Arbyn, Phillip Bennett, Evangelos Paraskevaidis
BACKGROUND: The mean age of women undergoing local treatment for pre-invasive cervical disease (cervical intra-epithelial neoplasia; CIN) or early cervical cancer (stage IA1) is around their 30s and similar to the age of women having their first child. Local cervical treatment has been correlated to adverse reproductive morbidity in a subsequent pregnancy, however, published studies and meta-analyses have reached contradictory conclusions. OBJECTIVES: To assess the effect of local cervical treatment for CIN and early cervical cancer on obstetric outcomes (after 24 weeks of gestation) and to correlate these to the cone depth and comparison group used...
November 2, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29094369/effect-of-inter-twin-delivery-interval-on-umbilical-artery-ph-and-apgar-score-in-the-second-twin
#6
Alon Tal, Hadar Peretz, Gali Garmi, Noah Zafran, Shabtai Romano, Raed Salim
BACKGROUND: To examine the effect of inter-twin delivery interval on umbilical artery pH and Apgar score of the second twin after vaginal delivery of the first twin. METHODS: Retrospective study conducted at a single teaching hospital. All pregnant women with twin gestation who delivered the first twin vaginally at more than 24 weeks between 1995 and 2015 were included. Major malformations and intrauterine deaths of one or both twins were excluded. Women were divided into those who had an inter-twin delivery interval of less than 30 minutes (group 1) or 30 minutes or more (group 2)...
November 2, 2017: Birth
https://www.readbyqxmd.com/read/29081573/turn-taking-in-cooperative-offspring-care-by-product-of-individual-provisioning-behavior-or-active-response-rule
#7
James L Savage, Lucy E Browning, Andrea Manica, Andrew F Russell, Rufus A Johnstone
ABSTRACT: For individuals collaborating to rear offspring, effective organization of resource delivery is difficult because each carer benefits when the others provide a greater share of the total investment required. When investment is provided in discrete events, one possible solution is to adopt a turn-taking strategy whereby each individual reduces its contribution rate after investing, only increasing its rate again once another carer contributes. To test whether turn-taking occurs in a natural cooperative care system, here we use a continuous time Markov model to deduce the provisioning behavior of the chestnut-crowned babbler (Pomatostomus ruficeps), a cooperatively breeding Australian bird with variable number of carers...
2017: Behavioral Ecology and Sociobiology
https://www.readbyqxmd.com/read/29076539/cesarean-delivery-changes-the-natural-position-of-the-uterus-on-transvaginal-ultrasonography
#8
Andrea Kaelin Agten, Anne Honart, Ana Monteagudo, Spencer McClelland, Basmy Basher, Ilan E Timor-Tritsch
OBJECTIVES: To assess whether cesarean delivery changes the natural position of the uterus. METHODS: In this retrospective Institutional Review Board-approved cohort study, we conducted a search of our university gynecologic ultrasonography (US) database. Patients with transvaginal US images before and after either vaginal or cesarean delivery between 2012 and 2015 were included. Women with prior cesarean delivery were excluded. Two readers independently measured antepartum and postpartum flexion angles between the longitudinal axis of the uterine body and the cervix...
October 27, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29048415/antenatal-methadone-vs-buprenorphine-exposure-and-length-of-hospital-stay-in-infants-admitted-to-the-intensive-care-unit-with-neonatal-abstinence-syndrome
#9
V N Tolia, K Murthy, M M Bennett, E S Miller, D K Benjamin, P B Smith, R H Clark
OBJECTIVE: Antenatal exposure to methadone or buprenorphine often causes neonatal abstinence syndrome (NAS) in newborns. However, comparative effects on affected infants' hospital courses are inconclusive. We sought to estimate the relationship of antenatal exposure with methadone or buprenorphine and infants' length of stay among hospitalized infants with NAS. STUDY DESIGN: This was a retrospective cohort study of hospitalized infants with NAS with either maternal exposure...
October 19, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28960732/estimated-rates-of-influenza-associated-outpatient-visits-during-2001-2010-in-six-us-integrated-health-care-delivery-organizations
#10
Hong Zhou, William W Thompson, Edward A Belongia, Ashley Fowlkes, Roger Baxter, Steven J Jacobsen, Michael L Jackson, Jason M Glanz, Allison L Naleway, Derek C Ford, Eric Weintraub, David K Shay
BACKGROUND: Population-based estimates of influenza-associated outpatient visits including both pandemic and inter-pandemic seasons are uncommon. Comparisons of such estimates with laboratory-confirmed rates of outpatient influenza are rare. OBJECTIVE: To estimate influenza-associated outpatient visits in six US integrated health care delivery organizations enrolling ~7.7 million persons. METHODS: Using negative-binomial regression methods, we modeled rates of influenza-associated visits with ICD-9-CM-coded pneumonia or acute respiratory outpatient visits during 2001-10...
September 27, 2017: Influenza and Other Respiratory Viruses
https://www.readbyqxmd.com/read/28910593/construction-of-a-north-american-cancer-survival-index-to-measure-progress-of-cancer-control-efforts
#11
Christopher J Johnson, Hannah K Weir, Angela Mariotto, Reda Wilson, Diane Nishri
INTRODUCTION: Population-based cancer survival data provide insight into the effectiveness of health care delivery. Comparing survival for all cancer sites combined is challenging, because the primary cancer site and age distribution of patients may differ among areas or change over time. Cancer survival indices (CSIs) are summary measures of survival for cancers of all sites combined and are used in England and Europe to monitor temporal trends and examine geographic differences in survival...
September 14, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28669538/the-effect-of-methylphenidate-on-the-microstructure-of-schedule-induced-polydipsia-in-an-animal-model-of-adhd
#12
Javier Íbias, Carter W Daniels, Miguel Miguéns, Ricardo Pellón, Federico Sanabria
Schedule-induced polydipsia (SIP) was established in spontaneously hypertensive rats (SHR), Wistar Kyoto rats (WKY), and Wistar rats, using a multiple fixed-time (FT) schedule of food delivery, with 30- and 90-s components. Thereafter, animals were exposed to methylphenidate (MPH; 2.5mg/kg/d) for six consecutive SIP sessions. A test to assess possible sensitization effects was also conducted four days after termination of the drug treatment. At baseline, FT 90-s produced longer and more frequent drinking episodes in SHR than in WKY...
June 30, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28661110/-single-fetal-demise-in-monochorionic-twins
#13
REVIEW
Isaac Blickstein
Single fetal death in a monochorionic twin pregnancy is more frequent than in a dichorionic twin gestation. Due to inter-twin vascular anastomosis in the monochorionic common placenta, the death of one twin causes a drop in blood pressure due to a shift of blood from the survivor to the dead fetus. If the drop of blood pressure is abrupt and serious, the survivor will die soon after (as occurs in 15% of cases). If the drop is less serious, the survivor may sustain ischemic injury (in about 26% of the cases) and if the drop in blood pressure is subtle, the survivor will be intact...
June 2017: Harefuah
https://www.readbyqxmd.com/read/28526451/interdelivery-weight-gain-and-risk-of-cesarean-delivery-following-a-prior-vaginal-delivery
#14
Annie M Dude, Abbi D Lane-Cordova, William A Grobman
BACKGROUND: Approximately one third of all deliveries in the United States are via cesarean. Previous research indicates weight gain during pregnancy is associated with an increased risk of cesarean delivery. It remains unclear, however, whether and to what degree weight gain between deliveries (ie, interdelivery weight gain) is associated with cesarean delivery in a subsequent pregnancy following a vaginal delivery. OBJECTIVES: The objective of the study was to determine whether interdelivery weight gain is associated with an increased risk of intrapartum cesarean delivery following a vaginal delivery...
September 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28421614/a-first-look-at-the-effects-of-long-inter-pregnancy-interval-and-advanced-maternal-age-on-perinatal-outcomes-a-retrospective-cohort-study
#15
Chunxiang Qin, Chunmei Mi, Aibin Xia, Wei-Ti Chen, Chunxia Chen, Ying Li, Yao Li, Wenhui Bai, Siyuan Tang
BACKGROUND: After China's One-child Policy was replaced with the Two-child Policy in 2013, the rate of second pregnancies with a longer inter-pregnancy interval (IPI) has suddenly increased in that country; however, the effect of long IPIs (≥49 months) on perinatal outcomes remains unreported. METHODS: This was a retrospective cohort study in China from July 2015 through June 2016. We used univariate and multivariate logistic regression models to test the associations among IPI, maternal age, and perinatal outcome (preterm delivery, term low birthweight, and small-for-gestational age)...
September 2017: Birth
https://www.readbyqxmd.com/read/28416742/model-driven-optimization-of-antiangiogenics-cytotoxics-combination-application-to-breast-cancer-mice-treated-with-bevacizumab-paclitaxel-doublet-leads-to-reduced-tumor-growth-and-fewer-metastasis
#16
Severine Mollard, Joseph Ciccolini, Diane-Charlotte Imbs, Raouf El Cheikh, Dominique Barbolosi, Sebastien Benzekry
Bevacizumab is the first-in-class antiangiogenic drug and is almost always administrated in combination with cytotoxics. Reports have shown that bevacizumab could induce a transient phase of vascular normalization, thus ensuring a better drug delivery when cytotoxics administration is adjuvant. However, determining the best sequence remains challenging. We have developed a mathematical model describing the impact of antiangiogenics on tumor vasculature. A 3.4 days gap between bevacizumab and paclitaxel was first proposed by our model...
April 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28395550/the-impact-of-inter-pregnancy-interval-on-subsequent-risk-of-preterm-birth
#17
Vid Janša, Isaac Blickstein, Miha Lučovnik, Vesna Fabjan-Vodušek, Ivan Verdenik, Nataša Tul
OBJECTIVE: The aim of the study was to assess optimal time to conceive after previous delivery associated with smallest risk of preterm birth. METHODS: We selected all women (n = 2723) with their first and second singleton delivery between the years 2004 and 2012. Inter-pregnancy interval was defined as that between live birth and subsequent conception. We performed logistic regression analyses to assess the risk of preterm birth adjusted for maternal age and body mass index...
April 11, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28390435/inter-pregnancy-interval-and-pregnancy-outcomes-among-women-with-delayed-childbearing-protocol-for-a-systematic-review
#18
Mani Asgharpour, Sofia Villarreal, Laura Schummers, Jennifer Hutcheon, Dorothy Shaw, Wendy V Norman
BACKGROUND: Women in high resource nations are increasingly delaying childbearing until their thirties. Delayed childbearing poses challenges for the spacing of a woman's pregnancies. Inter-pregnancy intervals <12 months are associated with risk for adverse pregnancy outcome, yet increased maternal age at delivery is linked with increased risk. The optimal inter-pregnancy interval for older mothers is uncertain. This systematic review will aim to assess the relation between inter-pregnancy interval and perinatal and maternal health outcomes in women who delay childbearing to age 30 and older...
April 8, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28256583/gene-networks-activated-by-specific-patterns-of-action-potentials-in-dorsal-root-ganglia-neurons
#19
Philip R Lee, Jonathan E Cohen, Dumitru A Iacobas, Sanda Iacobas, R Douglas Fields
Gene regulatory networks underlie the long-term changes in cell specification, growth of synaptic connections, and adaptation that occur throughout neonatal and postnatal life. Here we show that the transcriptional response in neurons is exquisitely sensitive to the temporal nature of action potential firing patterns. Neurons were electrically stimulated with the same number of action potentials, but with different inter-burst intervals. We found that these subtle alterations in the timing of action potential firing differentially regulates hundreds of genes, across many functional categories, through the activation or repression of distinct transcriptional networks...
March 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28222563/afferent-electrical-stimulation-during-cycling-improves-spinal-processing-of-sensorimotor-function-after-incomplete-spinal-cord-injury
#20
Stefano Piazza, Diego Serrano-Muñoz, Julio Gómez-Soriano, Diego Torricelli, Antonio Segura-Fragosa, José Luis Pons, Julian Taylor
OBJECTIVE: Appropriate afferent feedback delivery during the execution of motor tasks is important for rehabilitation after incomplete spinal cord injury (iSCI). However, during leg-cycling therapy, the plantar afferent feedback is minimal. We hypothesize that the augmentation of sensory input by combining cycling with a locomotor-like stimulation of plantar cutaneous innervations (ES-cycling), might help to restore proper spinal processing of sensorimotor function. METHODS: Thirteen non-injured subjects and 10 subjects with iSCI performed 10 minutes of cycling and, on another session, of ES-cycling...
2017: NeuroRehabilitation
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