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hetastarche AND open heart surgery

Michael Winterhalter, P Malinski, O Danzeisen, S Sixt, E Monaca, T Jüttner, M Peiper, P Kienbaum, A Koester, N Rahe-Meyer
BACKGROUND: the constantly growing amount of different kinds of colloid fluids necessitates comparative investigations with regards to the safety and effectivity in clinical use of these preparations. Hence we compared three colloid fluids in an observational study. The objective was the exploration of the influence of these three colloids on blood coagulation, hemodynamics and renal function of the cardiac surgical patient. METHODS: we included 90 patients undergoing an elective open-heart surgery with the use of the heart-lung machine and observed them consecutively...
September 24, 2010: European Journal of Medical Research
Zhi-bing Pi, Guan-xian Tan, Jun-lu Wang
OBJECTIVE: To observe the effect of hydroxyethyl starch (HES) 130/0.4 on S100B protein level and cerebral metabolism of oxygen in open cardiac surgery under cardiopulmonary bypass (CPB) and to explore whether it has the protective effect of 6%HES130/0.4 as priming solution on cerebral injury during CPB and explore the probable mechanism. METHODS: Forty patients with atrioseptal defect or ventricular septal defect scheduled for elective surgical repair under CPB with moderate hypothermia were randomly divided into two equal groups: HES 130/0...
July 17, 2007: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Erkan Iriz, Fersat Kolbakir, Haci Akar, Bahattin Adam, Hasan Tahsin Keceligil
BACKGROUND: Cognitive dysfunction (as an indicator of cerebral dysfunction after open heart surgery) was observed in as many as 70% of patients who underwent cardiopulmonary bypass. S-100beta protein is a sensitive indicator of cerebral injury. We aimed to compare the effects of hydroxyethyl starch and Ringer lactate prime solutions in the protection of cerebral tissue in cardiopulmonary bypass using serum S-100beta protein levels and informative cognitive tests. METHODS: Patients were randomized into two groups...
February 2005: Annals of Thoracic Surgery
D A Reuter, M S G Goepfert, T Goresch, M Schmoeckel, E Kilger, A E Goetz
BACKGROUND: Measurement of ventilation-induced left ventricular stroke volume variations (SVV) or pulse pressure variations (PPV) is useful to optimize preload in patients after cardiac surgery. The aim of this study was to investigate the ability of SVV and PPV measured by arterial pulse contour analysis to assess fluid responsiveness in patients undergoing coronary artery bypass surgery during open-chest conditions. METHODS: We studied 22 patients immediately after midline sternotomy...
March 2005: British Journal of Anaesthesia
I Celik, B Stinner, T Thiel, A Bauhofer, M Rothmund, W Dietz
OBJECTIVE: Antibiotic prophylaxis is used in many surgical procedures but there are frequent cardiovascular instabilities following antibiotics in perioperative period. A clinic modelling randomised trial (CMRT) in pigs was developed to compare the effects of 2 commonly used antibiotic combinations on cardiovascular stability during major surgery. MATERIALS AND METHODS: Thirty pigs (both sexes) were randomised into 3 groups, receiving either saline (placebo), co-amoxiclav or cefuroxime/metronidazole in clinically relevant doses as antibiotic prophylaxis...
August 2004: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
T Tuppurainen, J Mäkinen, M Salonen
BACKGROUND: About 27% of the population is known to have a patent foramen ovale. It can be opened if the left atrial pressure is less than the right atrial pressure. This pressure reversal has been reported during gynecologic laparoscopic surgery. The present paper describes with help of transesophageal echocardiography the pressure relationship between the atria during laparoscopic surgery and the effect of volume preload. METHODS: Twenty-one gynecologic ASA 1-3 patients were included in this open study...
January 2002: Acta Anaesthesiologica Scandinavica
S E Menth-Meier, R Imoberdorf, B Regli, B Kipfer, M Turgay, P E Ballmer
OBJECTIVE: Validation of plasma volume (PV) determination by indocyanine green (ICG) in comparison to the gold-standard method with radioiodinated albumin, and investigation of the effect of commonly used plasma expanders (albumin, hydroxyethyl starch, and polygelatine) on PV in the early postoperative phase in patients undergoing cardiac surgery. DESIGN: Prospective clinical study. SETTING: Department of medicine and intensive care unit at a university hospital...
May 2001: Intensive Care Medicine
Y Takahashi, K Tatsuno, T Kikuchi, Y Suzuki, K Kasahara, T Furusawa, Y Okada
To avoid any blood or protein transfusions, we employed 6% hydroxyethyl starch in 0.9% saline (saline HES) during cardiopulmonary bypass (CPB) for intracardiac repair in 24 consecutive patients with Tetralogy of Fallot (TF). The postoperative course has been satisfactory (central venous pressure 9.5 +/- 1.2 cmH2O, duration of intubation after surgery 4.4 +/- 1.5 hours), and all patients but one did not require transfusion therapy during their hospital stay. We conclude that intracardiac repair without transfusions is feasible in almost all patients with TF, when substituting saline HES for blood or proteins...
May 1997: [Zasshi] [Journal]
R A Moggio, C C Rha, E D Somberg, P I Praeger, R W Pooley, G E Reed
The hemodynamic effects of 2 plasma volume expanders were compared in postoperative open heart surgery patients. Albumin 5% (A) or hydroxyethyl starch 6% (HES) solutions were infused according to indications based on cardiac index (CI) and pulmonary wedge pressure (WP), and their effects evaluated by physiologic profile measurements. Both groups demonstrated significant increases with volume infusion in CI (A from 2.37 to 2.84; HES from 1.97 to 2.49 L/min X m2) and WP (A from 9.4 to 13.7 mm Hg; HES from 11...
December 1983: Critical Care Medicine
J Boldt, B Zickmann, C Herold, M Ballesteros, F Dapper, G Hempelmann
We have studied the effects of two types of volume replacement on the microcirculation in an open, controlled study in 45 patients undergoing aorto-coronary bypass grafting whose pulmonary capillary wedge pressure (PCWP) was less than 5 mm Hg. Hypertonic saline prepared in hydroxyethylstarch solution (HS-HES, n = 15) and 6% HES 200/0.5 solution (6% HES; n = 15) were infused randomly before operation in order to double the PCWP. Patients not given an infusion served as controls (n = 15). Skin microcirculatory blood flow was investigated by laser Doppler flow (LDF) measured simultaneously at the forearm and forehead before and after cardiopulmonary bypass (CPB)...
November 1991: British Journal of Anaesthesia
M E Villarino, S M Gordon, C Valdon, D Potts, K Fish, C Uyeda, P M McCarthy, L A Bland, R L Anderson, W R Jarvis
OBJECTIVE: To investigate a cluster of postoperative bleeding following open heart surgery. DESIGN: A cohort and case/control study. SETTING: Palo Alto Veterans Administration Medical Center, Palo Alto, California. PARTICIPANTS: Six (21.4%) of 28 patients undergoing open heart surgery who developed severe, nonsurgical, postoperative bleeding from July 1 through August 30, 1988 (outbreak period). All case-patients had chest tube drainage of greater than or equal to 1000 ml within 4 hours of surgery but did not have identifiable bleeding vessel(s) on exploration...
May 1992: Infection Control and Hospital Epidemiology
T Ohya, S Ishiai, H Tsuda, J Nakagawa, M Nishihara, H Kazuno, T Wada, T Maeba, K Shiota, J Mizushima, K Tanikawa, M Okazaki
No abstract text is available yet for this article.
December 1977: Kyobu Geka. the Japanese Journal of Thoracic Surgery
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