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Right ventricular decompensation

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https://www.readbyqxmd.com/read/29224256/echocardiographic-estimates-of-right-ventricular-systolic-function-in-dogs-with-myxomatous-mitral-valve-disease
#1
E H Chapel, B A Scansen, K E Schober, J D Bonagura
BACKGROUND: Right ventricular (RV) dysfunction independently predicts outcomes in human myxomatous mitral valve disease (MMVD). There is limited information regarding RV systolic function in dogs with MMVD. HYPOTHESIS: Right ventricular systolic function differs among stages of disease, decreasing in decompensated MMVD. ANIMALS: Thirty-sixclient-owned dogs with MMVD not receiving oral cardiovascular medications. METHODS: Prospective clinical study...
December 10, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29185616/incremental-prognostic-value-of-conventional-echocardiography-in-patients-with-acutely-decompensated-heart-failure
#2
Fabio Luis de Jesus Soares, Janine Magalhães Garcia de Oliveira, Gabriel Neimann da Cunha Freire, Lucas Carvalho Andrade, Marcia Maria Noya-Rabelo, Luis Claudio Lemos Correia
BACKGROUND: Acutely decompensated heart failure (ADHF) presents high morbidity and mortality in spite of therapeutic advance. Identifying factors of worst prognosis is important to improve assistance during the hospital phase and follow-up after discharge. The use of echocardiography for diagnosis and therapeutic guidance has been of great utility in clinical practice. However, it is not clear if it could also be useful for risk determination and classification in patients with ADHF and if it is capable of adding prognostic value to a clinical score (OPTIMIZE-HF)...
November 27, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29141964/acute-decompensated-pulmonary-hypertension
#3
Laurent Savale, Jason Weatherald, Xavier Jaïs, Constance Vuillard, Athénaïs Boucly, Mitja Jevnikar, David Montani, Olaf Mercier, Gerald Simonneau, Elie Fadel, Olivier Sitbon, Marc Humbert
Acute right heart failure in chronic precapillary pulmonary hypertension is characterised by a rapidly progressive syndrome with systemic congestion resulting from impaired right ventricular filling and/or reduced right ventricular flow output. This clinical picture results from an imbalance between the afterload imposed on the right ventricle and its adaptation capacity. Acute decompensated pulmonary hypertension is associated with a very poor prognosis in the short term. Despite its major impact on survival, its optimal management remains very challenging for specialised centres, without specific recommendations...
December 31, 2017: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/29124030/large-atrial-septal-defect-closure-in-a-patient-with-severe-pulmonary-arterial-hypertension
#4
Supomo Supomo, Anggoro Budi Hartopo, Dyah Wulan Anggrahini, Handy Darmawan, Lucia Kris Dinarti
Patients with an atrial septal defect (ASD) and severe pulmonary arterial hypertension (PAH) are considered ineligible for defect closure surgery because of the risk of right ventricular decompensation and death after the operation. We report the case of a patient with large ASD and severe PAH who was able to undergo defect closure surgery successfully following long-term use of combined oral sildenafil and beraprost.
October 2017: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29098525/prognostic-value-of-real-time-three-dimensional-echocardiography-compared-to-two-dimensional-echocardiography-in-patients-with-systolic-heart-failure
#5
Frederico J N Mancuso, Valdir A Moises, Dirceu R Almeida, Dalva Poyares, Luciana J Storti, Flavio S Brito, Sergio Tufik, Angelo A V de Paola, Antonio C C Carvalho, Orlando Campos
Heart failure (HF) is associated with morbidity and mortality. Real-time three-dimensional echocardiography (RT3DE) may offer additional prognostic data in patients with HF. The study aimed to evaluate the prognostic value of real-time three-dimensional echocardiography (RT3DE). This is a prospective study that included 89 patients with HF and left ventricular ejection fraction (LVEF) < 0.50 who were followed for 48 months. Left atrium and ventricular volumes and functions were evaluated by RT3DE. TDI and two-dimensional echocardiography parameters were also obtained...
November 2, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29097426/the-emerging-role-of-angiogenesis-in-adaptive-and-maladaptive-right-ventricular-remodeling-in-pulmonary-hypertension
#6
Andrea L Frump, Sebastien Bonnet, Vinicio A de Jesus Perez, Tim Lahm
Right ventricular (RV) function is the primary prognostic factor for both morbidity and mortality in pulmonary hypertension (PH). RV hypertrophy is initially an adaptive physiological response to increased overload; however, with persistent and/or progressive afterload increase, this response frequently transitions to more pathological maladaptive remodeling. The mechanisms and disease processes underlying this transition are mostly unknown. Angiogenesis has recently emerged as a major modifier of RV adaptation in the setting of pressure overload...
November 2, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/29044493/combining-echo-and-natriuretic-peptides-to-guide-heart-failure-care-in-the-outpatient-setting-a-position-paper
#7
REVIEW
Frank Lloyd Dini, Erberto Carluccio, Fabrizio Montecucco, Gian Marco Rosa, Paolo Fontanive
BACKGROUND: Chronic heart failure (HF) is a relevant and growing public health problem. Although the prognosis has recently improved, it remains a lethal disease, with a mortality that equals or exceeds that of many malignancies. Furthermore, chronic HF is costly, representing a large and growing drain on healthcare resources. METHODS: This narrative review is based on the material searched for and obtained via PubMed up to May 2017. The search terms we used were: "heart failure, echocardiography, natriuretic peptides" in combination with "treatment, biomarkers, guidelines"...
October 16, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28975959/challenges-of-congenital-heart-disease-in-grown-up-patients
#8
Markus Schwerzmann, Fabienne Schwitz, Corina Thomet, Alexander Kadner, Jean-Pierre Pfammatter, Kerstin Wustmann
Nowadays, more than 90% of all children born with congenital heart disease (CHD) reach adult life. Although initially considered to be cured, the majority of them continue to need specialised follow-up because they require re-do interventions or are at increased risk of cardiovascular complications and premature death. Arrhythmias are the most common cause of unscheduled hospital visits for grown-up CHD (GUCH) patients, accounting for one third of emergency admissions in these patients. Some GUCH patients are also at increased risk for sudden cardiac death...
October 4, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28966158/hybrid-transcatheter-left-ventricular-reconstruction-for-the-treatment-of-ischemic-cardiomyopathy
#9
Carlo Zivelonghi, Patrick Klein, Martin J Swaans, Pierfrancesco Agostoni
AIMS: Treatment of advanced ischemic cardiomyopathy is often challenging, with recurrent episodes of cardiac decompensation and consequent need for multiple hospitalizations. Mixed outcomes have been previously reported after conventional surgical left ventricle(LV) reconstruction. Aim of this report is to describe a novel hybrid transcatheter technique to reconstruct the remodeled LV. METHODS AND RESULTS: In this manuscript, we provide a detailed step-by-step description of a novel procedure, called Less Invasive Ventricular Enhancement(LIVE), which reconstructs the remodeled LV by plication of anteroseptal LV scar, thus reducing the enlarged volume, decreasing wall stress and increasing ejection fraction...
October 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28912975/an-incidentally-detected-right-ventricular-pseudoaneurysm
#10
Vamsi C Gaddipati, Angel I Martin, Mauricio O Valenzuela, Asef Mahmud, Aarti A Patel
Ventricular pseudoaneurysm is an uncommon, potentially fatal complication that has been associated with myocardial infarction, cardiac surgery, chest trauma, and infectious processes. Diagnosis can be challenging, as cases are rare and slowly progressing and typically lack identifiable features on clinical presentation. As a result, advanced imaging techniques have become the hallmark of identification. Ahead, we describe a patient who presents with acute decompensated heart failure and was incidentally discovered to have a large right ventricular pseudoaneurysm that developed following previous traumatic anterior rib fracture...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28834154/increased-myocardial-contractility-identifies-decompensated-cirrhotic-patients-requiring-liver-transplantation
#11
Christian Jansen, Alexander Cox, Robert Schueler, Matthias Schneider, Jennifer Lehmann, Michael Praktiknjo, Alessandra Pohlmann, Johannes Chang, Steffen Manekeller, Georg Nickenig, Gabriela Berlakovich, Christian P Strassburg, Christoph Hammerstingl, Katharina Staufer, Jonel Trebicka
BACKGROUND: Late allocation of organs for transplant impairs post liver transplant (LT) survival. Cardiac dysfunction, especially diastolic and autonomic dysfunction, is frequent and plays an important role in the prognosis of cirrhotic patients. However, the role of myocardial contractility is unexplored and its prognostic value is controversially discussed. This study analyses the role of myocardial contractility assessed by speckle tracking echocardiography in LT allocation. METHODS: 168 cirrhotic patients (training cohort: 111, validation cohort: 57) awaiting LT in two centers were included in this retrospective study...
August 17, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28772056/right-ventricular-temporal-assist-device-for-cardiac-recompensation
#12
Isabell Yan, Hanno Grahn, Stefan Blankenberg, Dirk Westermann
In this case report, we discuss treatment of a 66-year-old patient with right heart failure due to chronic left heart failure caused by ischemic cardiomyopathy. We decided to manage this patient by implanting a temporary right ventricular assist device (Impella RP®) as a novel therapeutic option for acute on chronic right heart decompensation.
August 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28759541/traumatic-ventricular-septal-defect-after-stab-wound-to-the-chest-missed-by-transthoracic-echocardiography-a-case-report
#13
Abimbola O Faloye, Raphael Y Gershon
Traumatic ventral septal defect may be sustained after either blunt force or penetrating trauma to the chest. Severity ranges from asymptomatic to acute decompensated heart failure. Our patient suffered a stab wound to the chest and was initially taken to the operating room for repair of a lacerated right ventricle. Subsequent postoperative hemodynamic deterioration prompted a bedside transthoracic echocardiogram, which failed to identify causal factors. A transesophageal echocardiogram performed immediately after ventral septal defect was demonstrated...
August 1, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28731484/cpr-ecls-bvad-and-successful-heart-transplantation-within-2-months-a-single-centre-case-series-in-two-young-high-urgency-listed-patients
#14
Anna K Schmidt, Diyar Saeed, Arash Mehdiani, Bozena Sowinski, Ralf Westenfeld, Payam Akhyari, Artur Lichtenberg, Udo Boeken
INTRODUCTION: In times of organ shortage, death while on the heart waiting-list still represents a major problem. As a consequence, bridging to transplant as well as the decision when to escalate therapy play a very important role. METHODS AND RESULTS: We report on two young patients with dilated cardiomyopathy and acute decompensation who were successfully bridged to heart transplantation with both left and temporary right ventricular assist devices in just 2 months...
July 20, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/28712955/clinical-impact-of-changes-in-hemodynamic-indices-of-contractile-function-during-treatment-of-acute-decompensated-heart-failure
#15
Kenneth C Bilchick, Eliany Mejia-Lopez, Peter McCullough, Khadijah Breathett, Jamie L Kennedy, Jose Tallaj, James Bergin, Salpy Pamboukian, Mohammad Abuannadi, Sula Mazimba
BACKGROUND: The objective of this work was to determine the impact of improving right ventricular versus left ventricular stroke work indexes (RVSWI vs LVSWI) during therapy for acute decompensated heart failure (ADHF). METHODS AND RESULTS: Cox proportional hazards regression and logistic regression were used to analyze key factors associated with outcomes in 175 patients (mean age 56.7 ± 13.6 years, 29.1% female) with hemodynamic data from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness trial...
July 13, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/28694355/peripheral-venous-pressure-measurements-in-patients-with-acute-decompensated-heart-failure-pvp-hf
#16
Brett W Sperry, Joseph Campbell, Marat Yanavitski, Samir Kapadia, W H Wilson Tang, Mazen Hanna
BACKGROUND: Accurate assessment of volume status is essential in diagnosis and guidance of decongestive therapy in patients with acute heart failure. We sought to compare peripheral venous pressure (PVP) with central venous pressure (CVP), as well as other invasive hemodynamic measurements, in patients hospitalized with an acute heart failure syndrome. METHODS AND RESULTS: PVP-HF (Peripheral Venous Pressure Measurements in Patients With Acute Decompensated Heart Failure) was a single-center prospective study, which enrolled patients admitted with acute heart failure, regardless of ejection fraction or disease pathogenesis...
July 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28668305/detrimental-role-of-lysyl-oxidase-in-cardiac-remodeling
#17
Elia C El Hajj, Milad C El Hajj, Van K Ninh, Jessica M Bradley, Mario A Claudino, Jason D Gardner
A key feature of heart failure is adverse extracellular matrix (ECM) remodeling, which is associated with increases in the collagen cross-linking enzyme, lysyl oxidase (LOX). In this study, we assess the progression of cardiovascular remodeling from the compensatory to decompensatory phase, with a focus on the change in LOX expression and activity as it relates to alterations in ECM composition and changes in cardiac function. Adult male Sprague-Dawley rats were studied after 4, 14, or 21weeks of aortocaval fistula-induced volume overload (VO)...
August 2017: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/28628000/epigenetics-inflammation-and-metabolism-in-right-heart-failure-associated-with-pulmonary-hypertension
#18
Nolwenn Samson, Roxane Paulin
Right ventricular failure (RVF) is the most important prognostic factor for both morbidity and mortality in pulmonary arterial hypertension (PAH), but also occurs in numerous other common diseases and conditions, including left ventricle dysfunction. RVF remains understudied compared with left ventricular failure (LVF). However, right and left ventricles have many differences at the morphological level or the embryologic origin, and respond differently to pressure overload. Therefore, knowledge from the left ventricle cannot be extrapolated to the right ventricle...
July 2017: Pulmonary Circulation
https://www.readbyqxmd.com/read/28595772/prevention-of-early-complications-and-late-consequences-after-acute-pulmonary-embolism-focus-on-reperfusion-techniques
#19
Stavros V Konstantinides, Stefano Barco
Pulmonary embolism (PE) is a major cause of acute cardiovascular mortality and long-term morbidity. Right ventricular (RV) dysfunction is the key determinant of prognosis in the acute phase of PE, and residual RV dysfunction is associated with the development of post-PE functional impairment, chronic thromboembolic disease, and higher costs of treatment over the long term. Patients with clinically overt RV failure, i.e. hemodynamic collapse at presentation (high-risk PE), necessitate immediate thrombolytic treatment to relieve the obstruction in the pulmonary circulation; surgical or catheter-directed removal of the thrombus can be an alternative option...
June 1, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/28528661/right-sided-cardiac-dysfunction-in-heart-failure-with-preserved-ejection-fraction-and-worsening-renal-function
#20
Monica Mukherjee, Kavita Sharma, Jose A Madrazo, Ryan J Tedford, Stuart D Russell, Allison G Hays
In urban populations, worsening renal function (WRF) is well established in patients hospitalized with acute decompensated heart failure with preserved ejection fraction (HFpEF). However, the mechanisms for development of WRF in the setting of acute HF in HFpEF are unclear. In the present study, we sought to characterize conventional echocardiographic measures of right ventricular (RV) chamber size and function to determine whether RV dysfunction and/or adverse RV remodeling is related to WRF in patients with HFpEF...
July 15, 2017: American Journal of Cardiology
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