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https://www.readbyqxmd.com/read/27917961/trends-in-health-surveillance-and-joint-service-delivery-for-pastoralists-in-west-and-central-africa
#1
M F Abakar, E Schelling, M Béchir, B N Ngandolo, K Pfister, I O Alfaroukh, H M Hassane, J Zinsstag
In most sub-Saharan African countries, pastoralism represents an important economic resource and contributes significantly to national growth; however, challenges remain, particularly in providing social services to pastoralists (especially health and education) and in avoiding conflict with local sedentary communities and local authorities. All of this takes place while pastoralists try to maintain their mobile lifestyle within a rapidly changing ecosystem. Transdisciplinary approaches, such as 'One Health', which covers both human and animal health, have proven effective in delivering services and reaching mobile pastoralists in remote areas...
November 2016: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/27906123/one-health-research-and-training-and-government-support-for-one-health-in-south-asia
#2
REVIEW
Joanna S McKenzie, Rojan Dahal, Manish Kakkar, Nitish Debnath, Mahmudur Rahman, Sithar Dorjee, Khalid Naeem, Tikiri Wijayathilaka, Barun Kumar Sharma, Nasir Maidanwal, Asmatullah Halimi, Eunmi Kim, Pranab Chatterjee, Brecht Devleesschauwer
INTRODUCTION: Considerable advocacy, funding, training, and technical support have been provided to South Asian countries to strengthen One Health (OH) collaborative approaches for controlling diseases with global human pandemic potential since the early 2000s. It is essential that the OH approach continues to be strengthened given South Asia is a hot spot for emerging and endemic zoonotic diseases. The objectives of this article are to describe OH research and training and capacity building activities and the important developments in government support for OH in these countries to identify current achievements and gaps...
2016: Infection Ecology & Epidemiology
https://www.readbyqxmd.com/read/27896606/a-knowledge-ecologies-analysis-of-co-designing-water-and-sanitation-services-in-alaska
#3
Dena Fam, Zoë Sofoulis
Willingness to collaborate across disciplinary boundaries is necessary but not sufficient for project success. This is a case study of a transdisciplinary project whose success was constrained by contextual factors that ultimately favoured technical and scientific forms of knowledge over the cultural intelligence that might ensure technical solutions were socially feasible. In response to Alaskan Water and Sewer Challenge (AWSC), an international team with expertise in engineering, consultative design and public health formed in 2013 to collaborate on a two-year project to design remote area water and sanitation systems in consultation with two native Alaskan communities...
November 28, 2016: Science and Engineering Ethics
https://www.readbyqxmd.com/read/27896289/how-who-and-when-preferences-for-delivery-of-genome-sequencing-results-among-women-diagnosed-with-breast-cancer-at-a-young-age
#4
Kimberly A Kaphingst, Jennifer Ivanovich, Ashley Elrick, Rebecca Dresser, Cindy Matsen, Melody S Goodman
BACKGROUND: The increasing use of genome sequencing with patients raises a critical communication challenge: return of secondary findings. While the issue of what sequencing results should be returned to patients has been examined, much less attention has been paid to developing strategies to return these results in ways that meet patients' needs and preferences. To address this, we investigated delivery preferences (i.e., who, how, when) for individual genome sequencing results among women diagnosed with breast cancer at age 40 or younger...
November 2016: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/27893987/transdisciplinary-approaches-enhance-the-production-of-translational-knowledge
#5
REVIEW
Timothy H Ciesielski, Melinda C Aldrich, Carmen J Marsit, Robert A Hiatt, Scott M Williams
The primary goal of translational research is to generate and apply knowledge that can improve human health. Although research conducted within the confines of a single discipline has helped us to achieve this goal in many settings, this unidisciplinary approach may not be optimal when disease causation is complex and health decisions are pressing. To address these issues, we suggest that transdisciplinary approaches can facilitate the progress of translational research, and we review publications that demonstrate what these approaches can look like...
November 10, 2016: Translational Research: the Journal of Laboratory and Clinical Medicine
https://www.readbyqxmd.com/read/27892616/a-policy-analysis-of-teamwork-as-a-proposal-for-healthcare-humanization-implications-for-nursing
#6
R N da Silva, F D da S de Freitas, F P de Araújo, M de A Ferreira
AIM: To analyse the implications of the political devices of the Brazilian National Humanization Policy, Singular Therapeutic Project and Reference Team and Matrix Support, for nursing as a professional discipline. BACKGROUND: The Brazilian Unified Health System, SUS-Brazil, has as its principles regarding health care: universal access at all levels of care; equality and non-discrimination; integrality; community participation; and political and administrative decentralization, regionalization, and hierarchization...
December 2016: International Nursing Review
https://www.readbyqxmd.com/read/27890689/developmental-toxicity-of-nicotine-a-transdisciplinary-synthesis-and-implications-for-emerging-tobacco-products
#7
REVIEW
Lucinda J England, Kjersti Aagaard, Michele Bloch, Kevin Conway, Kelly Cosgrove, Rachel Grana, Thomas J Gould, Dorothy Hatsukami, Frances Jensen, Denise Kandel, Bruce Lanphear, Frances Leslie, James R Pauly, Jenae Neiderhiser, Mark Rubinstein, Theodore A Slotkin, Eliot Spindel, Laura Stroud, Lauren Wakschlag
While the health risks associated with adult cigarette smoking have been well described, effects of nicotine exposure during periods of developmental vulnerability are often overlooked. Using MEDLINE and PubMed literature searches, books, reports and expert opinion, a transdisciplinary group of scientists reviewed human and animal research on the health effects of exposure to nicotine during pregnancy and adolescence. A synthesis of this research supports that nicotine contributes critically to adverse effects of gestational tobacco exposure, including reduced pulmonary function, auditory processing defects, impaired infant cardiorespiratory function, and may contribute to cognitive and behavioral deficits in later life...
November 24, 2016: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/27884523/the-anthroposphere-as-an-anticipatory-system-open-questions-on-steering-the-climate
#8
Rocco Scolozzi, Davide Geneletti
Climate change research and action counteracting it affect everyone and would involve cross-societal transformations reshaping the anthroposphere in its entirety. Scrutinizing climate-related science and policies, we recognize attempts to steer the evolution of climate according to expected (or modelled) futures. Such attempts would turn the anthroposphere into a large "anticipatory system", in which human society seeks to anticipate and, possibly, to govern climate dynamics. The chief aim of this discussion paper is to open a critical debate on the climate change paradigm (CCP) drawing on a strategic and systemic framework grounded in the concept of anticipatory system sensu Rosen (1991)...
November 22, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27854518/the-university-public-health-partnership-for-public-health-research-training-in-quebec-canada
#9
Gilles Paradis, Anne-Marie Hamelin, Maureen Malowany, Joseph Levy, Michel Rossignol, Pierre Bergeron, Natalie Kishchuk
Enhancing effective preventive interventions to address contemporary public health problems requires improved capacity for applied public health research. A particular need has been recognized for capacity development in population health intervention research to address the complex multidisciplinary challenges of developing, implementing, and evaluating public health practices, intervention programs, and policies. Research training programs need to adapt to these new realities. We have presented an example of a 2003 to 2015 training program in transdisciplinary research on public health interventions that embedded doctoral and postdoctoral trainees in public health organizations in Quebec, Canada...
November 17, 2016: American Journal of Public Health
https://www.readbyqxmd.com/read/27809394/precision-wildlife-medicine-applications-of-the-human-centred-precision-medicine-revolution-to-species-conservation
#10
Jenny Whilde, Mark Q Martindale, David J Duffy
The current species extinction crisis is being exacerbated by an increased rate of emergence of epizootic disease. Human-induced factors including habitat degradation, loss of biodiversity and wildlife population reductions resulting in reduced genetic variation are accelerating disease emergence. Novel, efficient and effective approaches are required to combat these epizootic events. Here, we present the case for the application of human precision medicine approaches to wildlife medicine in order to enhance species conservation efforts...
November 3, 2016: Global Change Biology
https://www.readbyqxmd.com/read/27805284/susceptibility-loci-of-cnot6-in-the-general-mrna-degradation-pathway-and-lung-cancer-risk-a-re-analysis-of-eight-gwass
#11
Fei Zhou, Yanru Wang, Hongliang Liu, Neal Ready, Younghun Han, Rayjean J Hung, Yonathan Brhane, John McLaughlin, Paul Brennan, Heike Bickeböller, Albert Rosenberger, Richard S Houlston, Neil Caporaso, Maria Teresa Landi, Irene Brüske, Angela Risch, Yuanqing Ye, Xifeng Wu, David C Christiani, Gary Goodman, Chu Chen, Christopher I Amos, Wei Qingyi
PURPOSE: mRNA degradation is an important regulatory step for controlling gene expression and cell functions. Genetic abnormalities involved in mRNA degradation genes were found to be associated with cancer risk. Therefore, we systematically investigated the roles of genetic variants in the general mRNA degradation pathway in lung cancer risk. EXPERIMENTAL DESIGN: Meta-analyses were conducted using summary data from six lung cancer genome-wide association studies (GWASs) from the Transdisciplinary Research in Cancer of the Lung and additional two GWASs from Harvard University and deCODE in the International Lung Cancer Consortium...
November 2, 2016: Molecular Carcinogenesis
https://www.readbyqxmd.com/read/27791981/advancing-alternative-analysis-integration-of-decision-science
#12
REVIEW
Timothy F Malloy, Virginia M Zaunbrecher, Christina Batteate, Ann Blake, William F Carroll, Charles J Corbett, Steffen Foss Hansen, Robert Lempert, Igor Linkov, Roger McFadden, Kelly D Moran, Elsa Olivetti, Nancy Ostrom, Michelle Romero, Julie Schoenung, Thomas Seager, Peter Sinsheimer, Kristina Thayer
BACKGROUND: Decision analysis-a systematic approach to solving complex problems-offers tools and frameworks to support decision making that are increasingly being applied to environmental challenges. Alternatives analysis is a method used in regulation and product design to identify, compare, and evaluate the safety and viability of potential substitutes for hazardous chemicals. OBJECTIVES: Assess whether decision science may assist the alternatives analysis decision maker in comparing alternatives across a range of metrics...
October 28, 2016: Environmental Health Perspectives
https://www.readbyqxmd.com/read/27758938/occupational-stress-a-comprehensive-review-of-the-top-50-annual-and-lifetime-cited-articles
#13
Behdin Nowrouzi, Christine Nguyen, Jennifer Casole, Behnam Nowrouzi-Kia
This study determined the impact and influence of published articles on the field of occupational stress. A transdisciplinary approach was used to identify the 50 work-related stress articles with the most lifetime citations and the 50 work-related stress articles with the highest annual citation rates. Studies were categorized based on their primary focus: (a) etiology, (b) predictor of outcome for which occupational stress is the outcome or predictor of outcome for which occupational stress is an independent variable, (c) management/intervention, (d) theory/model/framework, or (e) methodologies...
October 6, 2016: Workplace Health & Safety
https://www.readbyqxmd.com/read/27751865/a-mixed-methods-approach-to-assess-animal-vaccination-programmes-the-case-of-rabies-control-in-bamako-mali
#14
Laura Mosimann, Abdallah Traoré, Stephanie Mauti, Monique Léchenne, Brigit Obrist, René Véron, Jan Hattendorf, Jakob Zinsstag
In the framework of the research network on integrated control of zoonoses in Africa (ICONZ) a dog rabies mass vaccination campaign was carried out in two communes of Bamako (Mali) in September 2014. A mixed method approach, combining quantitative and qualitative tools, was developed to evaluate the effectiveness of the intervention towards optimization for future scale-up. Actions to control rabies occur on one level in households when individuals take the decision to vaccinate their dogs. However, control also depends on provision of vaccination services and community participation at the intermediate level of social resilience...
October 14, 2016: Acta Tropica
https://www.readbyqxmd.com/read/27747110/ectopic-thyroid-at-the-base-of-the-tongue-of-a-young-patient
#15
Paulo Henrique de Souza Castro, Luiz Evaristo Ricci Volpato, Julia Tramujas, Alvaro Henrique Borges
Lingual thyroid is defined as an ectopic thyroid gland tissue located in the midline of the tongue base and it is uncommonly observed in clinical practice and is rare in children. This paper describes the surgical treatment of ectopic thyroid at the base of the tongue in a child. The chief complaint of the 12-year-old, melanodermic female patient was the difficulty to swallow for 15 days. The intraoral physical examination barely showed a nodular lesion at tongue base. The CT scan showed a round, well defined hyperdense lesion of approximately 25...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27739386/allostatic-load-and-comorbidities-a-mitochondrial-epigenetic-and-evolutionary-perspective
#16
Robert-Paul Juster, Jennifer J Russell, Daniel Almeida, Martin Picard
Stress-related pathophysiology drives comorbid trajectories that elude precise prediction. Allostatic load algorithms that quantify biological "wear and tear" represent a comprehensive approach to detect multisystemic disease processes of the mind and body. However, the multiple morbidities directly or indirectly related to stress physiology remain enigmatic. Our aim in this article is to propose that biological comorbidities represent discrete pathophysiological processes captured by measuring allostatic load...
November 2016: Development and Psychopathology
https://www.readbyqxmd.com/read/27722880/the-deepwater-horizon-oil-spill-through-the-lens-of-human-health-and-the-ecosystem
#17
REVIEW
Maureen Lichtveld, Samendra Sherchan, Kaitlyn B Gam, Richard K Kwok, Christopher Mundorf, Arti Shankar, Lissa Soares
This review examines current research ascertaining the impact of the Deepwater Horizon oil spill on human health and ecosystems. Driven by the need to strategically focus research funding, the authors also assess the implications of those findings and promote a transdisciplinary research agenda addressing critical gaps.Epidemiologic studies conducted in workers and vulnerable communities in the spill's aftermath showed that non-chemical stressors affect resilience. Ecosystem-wise salt marsh species showed variability in structural and functional changes, attributed to species-specific tolerance, oil exposure, and belowground plant organs damage...
December 2016: Current Environmental Health Reports
https://www.readbyqxmd.com/read/27721917/molecular-pathological-epidemiology-in-diabetes-mellitus-and-risk-of-hepatocellular-carcinoma
#18
Chun Gao
Molecular pathological epidemiology (MPE) is a multidisciplinary and transdisciplinary study field, which has emerged as an integrated approach of molecular pathology and epidemiology, and investigates the relationship between exogenous and endogenous exposure factors, tumor molecular signatures, and tumor initiation, progression, and response to treatment. Molecular epidemiology broadly encompasses MPE and conventional-type molecular epidemiology. Hepatocellular carcinoma (HCC) is the third most common cause of cancer-associated death worldwide and remains as a major public health challenge...
September 28, 2016: World Journal of Hepatology
https://www.readbyqxmd.com/read/27717067/one-health-transdisciplinary-opportunities-for-setac-leadership-in-integrating-and-improving-the-health-of-people-animals-and-the-environment
#19
A Alonso Aguirre, Val R Beasley, Tom Augspurger, William H Benson, Janet Whaley, Niladri Basu
One Health is a collaborative, transdisciplinary effort working locally, nationally, and globally to improve health for people, animals, plants, and the environment. The term is relatively new (from ∼2003), and it is increasingly common to see One Health included by name in interinstitutional research partnerships, conferences, communications, and organizational frameworks, particularly those championed by the human health and veterinary medical communities. Environmental quality is arguably the least developed component within the One Health framework, but can be guided by expertise within the Society of Environmental Toxicology and Chemistry (SETAC)...
October 2016: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/27713484/a-novel-genetic-variant-in-long-non-coding-rna-gene-nexn-as1-is-associated-with-risk-of-lung-cancer
#20
Hua Yuan, Hongliang Liu, Zhensheng Liu, Kouros Owzar, Younghun Han, Li Su, Yongyue Wei, Rayjean J Hung, John McLaughlin, Yonathan Brhane, Paul Brennan, Heike Bickeboeller, Albert Rosenberger, Richard S Houlston, Neil Caporaso, Maria Teresa Landi, Joachim Heinrich, Angela Risch, David C Christiani, Zeynep H Gümüş, Robert J Klein, Christopher I Amos, Qingyi Wei
Lung cancer etiology is multifactorial, and growing evidence has indicated that long non-coding RNAs (lncRNAs) are important players in lung carcinogenesis. We performed a large-scale meta-analysis of 690,564 SNPs in 15,531 autosomal lncRNAs by using datasets from six previously published genome-wide association studies (GWASs) from the Transdisciplinary Research in Cancer of the Lung (TRICL) consortium in populations of European ancestry. Previously unreported significant SNPs (P value < 1 × 10(-7)) were further validated in two additional independent lung cancer GWAS datasets from Harvard University and deCODE...
October 7, 2016: Scientific Reports
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