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Behdin Nowrouzi, Christine Nguyen, Jennifer Casole, Behnam Nowrouzi-Kia
This study determined the impact and influence of published articles on the field of occupational stress. A transdisciplinary approach was used to identify the 50 work-related stress articles with the most lifetime citations and the 50 work-related stress articles with the highest annual citation rates. Studies were categorized based on their primary focus: (a) etiology, (b) predictor of outcome for which occupational stress is the outcome or predictor of outcome for which occupational stress is an independent variable, (c) management/intervention, (d) theory/model/framework, or (e) methodologies...
October 6, 2016: Workplace Health & Safety
Laura Mosimann, Abdallah Traoré, Stephanie Mauti, Monique Léchenne, Brigit Obrist, René Véron, Jan Hattendorf, Jakob Zinsstag
In the framework of the research network on integrated control of zoonoses in Africa (ICONZ) a dog rabies mass vaccination campaign was carried out in two communes of Bamako (Mali) in September 2014. A mixed method approach, combining quantitative and qualitative tools, was developed to evaluate the effectiveness of the intervention towards optimization for future scale-up. Actions to control rabies occur on one level in households when individuals take the decision to vaccinate their dogs. However, control also depends on provision of vaccination services and community participation at the intermediate level of social resilience...
October 14, 2016: Acta Tropica
Paulo Henrique de Souza Castro, Luiz Evaristo Ricci Volpato, Julia Tramujas, Alvaro Henrique Borges
Lingual thyroid is defined as an ectopic thyroid gland tissue located in the midline of the tongue base and it is uncommonly observed in clinical practice and is rare in children. This paper describes the surgical treatment of ectopic thyroid at the base of the tongue in a child. The chief complaint of the 12-year-old, melanodermic female patient was the difficulty to swallow for 15 days. The intraoral physical examination barely showed a nodular lesion at tongue base. The CT scan showed a round, well defined hyperdense lesion of approximately 25...
2016: Case Reports in Dentistry
Robert-Paul Juster, Jennifer J Russell, Daniel Almeida, Martin Picard
Stress-related pathophysiology drives comorbid trajectories that elude precise prediction. Allostatic load algorithms that quantify biological "wear and tear" represent a comprehensive approach to detect multisystemic disease processes of the mind and body. However, the multiple morbidities directly or indirectly related to stress physiology remain enigmatic. Our aim in this article is to propose that biological comorbidities represent discrete pathophysiological processes captured by measuring allostatic load...
November 2016: Development and Psychopathology
Maureen Lichtveld, Samendra Sherchan, Kaitlyn B Gam, Richard K Kwok, Christopher Mundorf, Arti Shankar, Lissa Soares
This review examines current research ascertaining the impact of the Deepwater Horizon oil spill on human health and ecosystems. Driven by the need to strategically focus research funding, the authors also assess the implications of those findings and promote a transdisciplinary research agenda addressing critical gaps.Epidemiologic studies conducted in workers and vulnerable communities in the spill's aftermath showed that non-chemical stressors affect resilience. Ecosystem-wise salt marsh species showed variability in structural and functional changes, attributed to species-specific tolerance, oil exposure, and belowground plant organs damage...
October 8, 2016: Current Environmental Health Reports
Chun Gao
Molecular pathological epidemiology (MPE) is a multidisciplinary and transdisciplinary study field, which has emerged as an integrated approach of molecular pathology and epidemiology, and investigates the relationship between exogenous and endogenous exposure factors, tumor molecular signatures, and tumor initiation, progression, and response to treatment. Molecular epidemiology broadly encompasses MPE and conventional-type molecular epidemiology. Hepatocellular carcinoma (HCC) is the third most common cause of cancer-associated death worldwide and remains as a major public health challenge...
September 28, 2016: World Journal of Hepatology
A Alonso Aguirre, Val R Beasley, Tom Augspurger, William H Benson, Janet Whaley, Niladri Basu
One Health is a collaborative, transdisciplinary effort working locally, nationally, and globally to improve health for people, animals, plants, and the environment. The term is relatively new (from ∼2003), and it is increasingly common to see One Health included by name in interinstitutional research partnerships, conferences, communications, and organizational frameworks, particularly those championed by the human health and veterinary medical communities. Environmental quality is arguably the least developed component within the One Health framework, but can be guided by expertise within the Society of Environmental Toxicology and Chemistry (SETAC)...
October 2016: Environmental Toxicology and Chemistry
Hua Yuan, Hongliang Liu, Zhensheng Liu, Kouros Owzar, Younghun Han, Li Su, Yongyue Wei, Rayjean J Hung, John McLaughlin, Yonathan Brhane, Paul Brennan, Heike Bickeboeller, Albert Rosenberger, Richard S Houlston, Neil Caporaso, Maria Teresa Landi, Joachim Heinrich, Angela Risch, David C Christiani, Zeynep H Gümüş, Robert J Klein, Christopher I Amos, Qingyi Wei
Lung cancer etiology is multifactorial, and growing evidence has indicated that long non-coding RNAs (lncRNAs) are important players in lung carcinogenesis. We performed a large-scale meta-analysis of 690,564 SNPs in 15,531 autosomal lncRNAs by using datasets from six previously published genome-wide association studies (GWASs) from the Transdisciplinary Research in Cancer of the Lung (TRICL) consortium in populations of European ancestry. Previously unreported significant SNPs (P value < 1 × 10(-7)) were further validated in two additional independent lung cancer GWAS datasets from Harvard University and deCODE...
October 7, 2016: Scientific Reports
Katherine Lippel, Joan M Eakin, D Linn Holness, Dana Howse
BACKGROUND: This study sought to identify impacts of compensation system characteristics on doctors in Québec and Ontario. METHODS: (i) Legal analysis; (ii) Qualitative methods applied to documentation and individual and group interviews with doctors (34) and other system participants (31); and (iii) Inter-jurisdictional transdisciplinary analysis involving cross-disciplinary comparative and integrative analysis of policy contexts, qualitative data, and the relationship between the two...
October 4, 2016: American Journal of Industrial Medicine
Robert F Tamburro, Tammara L Jenkins, Patrick M Kochanek
OBJECTIVE: To summarize the scientific priorities and potential future research directions for pediatric critical care research discussed by a panel of experts at the inaugural Strategic Planning Conference of the Pediatric Trauma and Critical Illness Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. DATA SOURCES: Expert opinion expressed during the Strategic Planning Conference. STUDY SELECTION: Not applicable...
September 27, 2016: Pediatric Critical Care Medicine
Krzysztof Jagla, Benoit Kalman, Thomas Boudou, Sylvie Hénon, Sabrina Batonnet-Pichon
The use of the adapted models to decipher patho-physiological mechanisms of human diseases is always a great challenge. This is of particular importance for early-onset myopathies, in which pathological mutations often impact not only on muscle structure and function but also on developmental processes. Mice are currently the main animal model used to study neuromuscular disorders including the early-onset myopathies. However strategies based on simple animal models and on transdisciplinary approaches exploring mechanical muscle cell properties emerge as attractive, non-exclusive alternatives...
September 23, 2016: Seminars in Cell & Developmental Biology
Isabel C Scarinci, Artisha Moore, Regina Benjamin, Selwyn Vickers, James Shikany, Mona Fouad
OBJECTIVE: We describe the formulation and implementation of a participatory evaluation plan for three Transdisciplinary Collaborative Centers for Health Disparities Research funded by the National Institute of Minority Health and Health Disparities. METHODS: Although different in scope of work, all three centers share a common goal of establishing sustainable centers in health disparities science in three priority areas - social determinants of health, men's health research, and health policy research...
September 13, 2016: Evaluation and Program Planning
Michael A Perelman
The Sexual Tipping Point(®) (STP) model is an integrated approach to the etiology, diagnosis and treatment of men with delayed ejaculation (DE), including all subtypes manifesting ejaculatory delay or absence [registered trademark owned by the MAP Educational Fund, a 501(c)(3) public charity]. A single pathogenetic pathway does not exist for sexual disorders generally and that is also true for DE specifically. Men with DE have various bio-psychosocial-behavioral & cultural predisposing, precipitating, maintaining, and contextual factors which trigger, reinforce, or worsen the probability of DE occurring...
August 2016: Translational Andrology and Urology
L Vaivre-Douret, A Boschi, M L Cuny, C Clouard, A Mosser, B Golse, A Philippe, M Bourgeois, N Boddaert, S Puget
: Left temporal arachnoid cyst and specific learning disorders associated with pervasive developmental disorders - not otherwise specified (PDD-NOS): contributions of an integrative neuro-psychomotor, neuropsychological, psychopathological and neurosurgical approach about a case report in a child (François). With DSM-IV and DSM-IV-TR, the terminology of pervasive developmental disorders (PDD) covers two main categories of infantile disorders: disorders of "strictly" autistic nature and pervasive developmental disorders - not otherwise specified (PDD-NOS)...
September 16, 2016: L'Encéphale
Andrés Felipe SantoDomingo, Laura Castro-Díaz, Catalina González-Uribe
Eco-bio-social factors may increase or decrease a community's susceptibility to vector-borne disease transmission. Traditional studies have contributed information about the association between eco-bio-social factors and health outcomes, but few have provided this information in an integrative way characterizing annual dynamics among indigenous communities. Transdisciplinary research was conducted with the Bari of Karikachaboquira and the Wayúu of Marbacella and El Horno, using qualitative and participatory methods, including seasonal graphics, semi-structured interviews, geo-referencing routes, and participatory observation...
September 16, 2016: EcoHealth
Jo Marie Reilly
This commentary reflects the professional life story of a prolific and well-published poet, Howard Stein. An anthropologist by training, Howard's poetry is well known and well respected by family physicians. It is within family medicine that Howard found his professional home, and in his 45-plus-year career he has shared the value of "patient story"; the value of the doctor-patient relationship; and the art of listening deeply to self, colleagues, and patients. This commentary offers a tribute to Howard's professional life and his contributions to family and narrative medicine...
September 2016: Families, Systems & Health: the Journal of Collaborative Family Healthcare
Vahan Martirosian, Thomas C Chen, Michelle Lin, Josh Neman
Medulloblastomas are the most common malignant pediatric brain tumors. Over the past several decades, a wide range of tumor-centric studies have identified genes and their regulators within signaling pathways that promote medulloblastoma growth. This review aims to raise awareness that transdisciplinary research between developmental neurobiology and cancer foundations can advance our current understanding of how the nervous system contributes to medulloblastomas. By leveraging current advances in neurodevelopment, microenvironment (including secreted neuropeptides), neurotransmitters, and axon guidance cues, we can uncover novel mechanisms used by the nervous system to promote medulloblastoma growth and spread...
December 2016: Journal of Neuroscience Research
Sara Wylie, Kim Schultz, Deborah Thomas, Chris Kassotis, Susan Nagel
This article describes Dr Theo Colborn's legacy of inspiring complementary and synergistic environmental health research and advocacy. Colborn, a founder of endocrine disruption research, also stimulated study of hydraulic fracturing (fracking). In 2014, the United States led the world in oil and gas production, with fifteen million Americans living within one mile of an oil or gas well. Colborn pioneered efforts to understand and control the impacts of this sea change in energy production. In 2005, her research organization The Endocrine Disruption Exchange (TEDX) developed a database of chemicals used in natural gas extraction and their health effects...
September 13, 2016: New Solutions: a Journal of Environmental and Occupational Health Policy: NS
W Schneiders, U Dittmann, F Hannemann, M Jäger, M Eberlein-Gonska, K D Schaser, H Zwipp, K-P Günther
Background: Since the combination of orthopaedic and traumatology surgery as a single speciality, an extremely wide variety of orthopaedic and trauma surgery centres have been founded in Germany. The present investigation analysed the degree to which additional value has been generated by merging two previously independent university departments - one for orthopaedics, the other for trauma surgery - into a single orthopaedics and trauma surgery centre. Material and Methods: The centre, merged in 1 June 2013, is led by two equal co-chairs (a full professor for orthopaedics and a full professor for trauma surgery)...
September 9, 2016: Zeitschrift Für Orthopädie und Unfallchirurgie
Alice A Kuo, Mienah Z Sharif, Michael L Prelip, Deborah C Glik, Stephanie L Albert, Thomas Belin, William J McCarthy, Christian K Roberts, Rosa Elena Garcia, Alexander N Ortega
Reducing health disparities is a national public health priority. Latinos represent the largest racial/ethnic minority group in the United States and suffer disproportionately from poor health outcomes, including cardiovascular disease risk. Academic training programs are an opportunity for reducing health disparities, in part by increasing the diversity of the public health workforce and by incorporating training designed to develop a skill set to address health disparities. This article describes the Training and Career Development Program at the UCLA Center for Population Health and Health Disparities: a multilevel, transdisciplinary training program that uses a community-engaged approach to reduce cardiovascular disease risk in two urban Mexican American communities...
September 8, 2016: Health Promotion Practice
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