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Weight Regain Prevention

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https://www.readbyqxmd.com/read/29343842/leptin-resistance-was-involved-in-susceptibility-to-overweight-in-the-striped-hamster-re-fed-with-high-fat-diet
#1
Ying Zhao, Li-Bing Chen, Si-Si Mao, Hong-Xia Min, Jing Cao
Food restriction (FR) is the most commonly used intervention to prevent the overweight. However, the lost weight is usually followed by "compensatory growth" when FR ends, resulting in overweight. The present study was aimed to examining the behavior patterns and hormones mechanisms underpinning the over-weight. Energy budget and body fat content, and several endocrine markers related to leptin signals were examined in the striped hamsters under 20% FR refed by either low-fat diet (LF group) or high-fat diet (HF group)...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29243354/effectiveness-of-extended-contact-interventions-for-weight-management-delivered-via-text-messaging-a-systematic-review-and-meta-analysis
#2
REVIEW
J R Job, B S Fjeldsoe, E G Eakin, M M Reeves
BACKGROUND: Extended contact interventions provide support for continued weight management (weight loss/prevention of weight regain) following a weight loss intervention. Text messages offer a medium for delivery in a potentially cost-effective, broad-reach manner. OBJECTIVES: This study aims to examine (i) the effectiveness of extended contact, text message interventions for adults in supporting weight management, and (ii) which intervention characteristics are common to those that are effective...
December 15, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29241540/lateral-hypothalamic-neurotensin-neurons-orchestrate-dual-weight-loss-behaviors-via-distinct-mechanisms
#3
Hillary L Woodworth, Bethany G Beekly, Hannah M Batchelor, Raluca Bugescu, Patricia Perez-Bonilla, Laura E Schroeder, Gina M Leinninger
The central mechanism by which neurotensin (Nts) potentiates weight loss has remained elusive. We leveraged chemogenetics to reveal that Nts-expressing neurons of the lateral hypothalamic area (LHA) promote weight loss in mice by increasing volitional activity and restraining food intake. Intriguingly, these dual weight loss behaviors are mediated by distinct signaling pathways: Nts action via NtsR1 is essential for the anorectic effect of the LHA Nts circuit, but not for regulation of locomotor or drinking behavior...
December 12, 2017: Cell Reports
https://www.readbyqxmd.com/read/29207379/practical-recommendations-of-the-obesity-management-task-force-of-the-european-association-for-the-study-of-obesity-for-the-post-bariatric-surgery-medical-management
#4
Luca Busetto, Dror Dicker, Carmil Azran, Rachel L Batterham, Nathalie Farpour-Lambert, Martin Fried, Jøran Hjelmesæth, Johann Kinzl, Deborah R Leitner, Janine M Makaronidis, Karin Schindler, Hermann Toplak, Volkan Yumuk
Bariatric surgery is today the most effective long-term therapy for the management of patients with severe obesity, and its use is recommended by the relevant guidelines of the management of obesity in adults. Bariatric surgery is in general safe and effective, but it can cause new clinical problems and is associated with specific diagnostic, preventive and therapeutic needs. For clinicians, the acquisition of special knowledge and skills is required in order to deliver appropriate and effective care to the post-bariatric patient...
December 6, 2017: Obesity Facts
https://www.readbyqxmd.com/read/29204255/bariatric-surgery-and-long-term-nutritional-issues
#5
REVIEW
Roberta Lupoli, Erminia Lembo, Gennaro Saldalamacchia, Claudia Kesia Avola, Luigi Angrisani, Brunella Capaldo
Bariatric surgery is recognized as a highly effective therapy for obesity since it accomplishes sustained weight loss, reduction of obesity-related comorbidities and mortality, and improvement of quality of life. Overall, bariatric surgery is associated with a 42% reduction of the cardiovascular risk and 30% reduction of all-cause mortality. This review focuses on some nutritional consequences that can occur in bariatric patients that could potentially hinder the clinical benefits of this therapeutic option...
November 15, 2017: World Journal of Diabetes
https://www.readbyqxmd.com/read/29117105/efficacy-of-web-based-weight-loss-maintenance-programs-a-randomized-controlled-trial-comparing-standard-features-versus-the-addition-of-enhanced-personalized-feedback-over-12-months
#6
Clare E Collins, Philip J Morgan, Melinda J Hutchesson, Christopher Oldmeadow, Daniel Barker, Robin Callister
Few randomized controlled trials (RCT) have evaluated the efficacy of web-based programs targeting maintenance of lost weight. The aims of this study were to evaluate two versions of a commercially available web-based weight loss maintenance (WLM) program and examine whether the provision of enhanced feedback was associated with better WLM. The study was an assessor-blinded RCT of change in body mass index (BMI) over 12 months WLM. Participants were 227 adults (44% male, 42.3 ± 10.1 years, BMI 30.4 ± 4.1 kg/m²) randomized to either a basic (Basic WLM) or enhanced program with additional support (Enhanced WLM)...
November 8, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/29104805/three-year-follow-up-of-participants-from-a-self-weighing-randomized-controlled-trial
#7
Lua Wilkinson, Carly R Pacanowski, David Levitsky
Frequent self-weighing is associated with weight loss maintenance. Several years ago, we investigated frequent self-weighing's effect on weight loss and found the participants lost a significant amount of weight. Three years after this trial's end, participants were contacted for an update on their weight and self-weighing frequency. Weight change and self-weighing frequency since the end of the study were assessed. We hypothesized that participants who maintained frequent self-weighing behavior would have maintained their weight loss...
2017: Journal of Obesity
https://www.readbyqxmd.com/read/29097359/customization-of-bilio-pancreatic-limb-length-to-modulate-and-sustain-anti-diabetic-effect-of-gastric-bypass-surgery
#8
Atanu Pal, David B Rhoads, Ali Tavakkoli
BACKGROUND: Although Roux-en-Y Gastric Bypass (RYGB) remains the most effective treatment for obesity and Type 2 Diabetes (T2D), many patients fail to achieve remission, or relapse. Increasing intestinal limb lengths of RYGB may improve outcomes, but the mechanistic basis for this remains unclear. We hypothesize Bilio-Pancreatic (BP) limb length modulates the anti-diabetic effect of RYGB. METHODS: Rats underwent RYGB with a 20-cm (RYGB-20cm) or 40-cm (RYGB-40cm) BP limb, and were compared to control animals...
November 2, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29064743/dipeptidyl-peptidase-4-inhibitor-sitagliptin-prevented-weight-regain-in-obese-women-with-polycystic-ovary-syndrome-previously-treated-with-liraglutide-a-pilot-randomized-study
#9
Simona Ferjan, Andrej Janez, Mojca Jensterle
BACKGROUND: Weight loss is often nonsustainable after liraglutide cessation. The present study is the first insight into the potential prevention of weight regain in obese subjects who have been withdrawn from liraglutide. We evaluated whether dipeptidyl peptidase-4 (DPP-4) inhibitor sitagliptin in adjunct to metformin prevents body weight regain more effectively than metformin alone in obese polycystic ovary syndrome (PCOS) previously treated with liraglutide. METHODS: A 12-week prospective randomized open-label study was conducted with 24 obese women with PCOS who had been pretreated with liraglutide 3...
October 24, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/29053636/neural-and-molecular-mechanisms-involved-in-controlling-the-quality-of-feeding-behavior-diet-selection-and-feeding-patterns
#10
REVIEW
Tsutomu Sasaki
We are what we eat. There are three aspects of feeding: what, when, and how much. These aspects represent the quantity (how much) and quality (what and when) of feeding. The quantitative aspect of feeding has been studied extensively, because weight is primarily determined by the balance between caloric intake and expenditure. In contrast, less is known about the mechanisms that regulate the qualitative aspects of feeding, although they also significantly impact the control of weight and health. However, two aspects of feeding quality relevant to weight loss and weight regain are discussed in this review: macronutrient-based diet selection (what) and feeding pattern (when)...
October 20, 2017: Nutrients
https://www.readbyqxmd.com/read/29049008/exogenous-murine-antimicrobial-peptide-cramp-significantly-exacerbates-ovalbumin-induced-airway-inflammation-but-ameliorates-oxazolone-induced-intestinal-colitis-in-balb-c-mice
#11
Yang Li, Xiaojie Chu, Cunbao Liu, Weiwei Huang, Yufeng Yao, Ye Xia, Pengyan Sun, Qiong Long, Xuejun Feng, Kui Li, Xu Yang, Hongmei Bai, Wenjia Sun, Yanbing Ma
Cathelicidin has been reported to be multifunctional. The current study aimed to investigate the influences of exogenous cathelicidin-related antimicrobial peptide (CRAMP) on inflammatory responses in different disease models. In OVA-induced allergic airway inflammation, CRAMP significantly enhanced the infiltration of inflammatory cells and accumulation of proinflammatory Th2 cytokine IL-13 and IL-33 in bronchial alveolar lavage fluid (BALF), exacerbated lung tissue inflammation and airway goblet cell hyperplasia, and elevated OVA-specific IgE level in serum...
October 19, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29046304/comparison-among-criteria-to-define-successful-weight-loss-maintainers-and-regainers-in-the-action-for-health-in-diabetes-look-ahead-and-diabetes-prevention-program-trials
#12
COMPARATIVE STUDY
Samantha E Berger, Gordon S Huggins, Jeanne M McCaffery, Alice H Lichtenstein
Background: Given the low rates of successful weight maintenance after lifestyle-induced weight loss, it is critical to develop approaches that distinguish successful weight-loss maintainers from regainers.Objective: The aim of this study was to compare published categorization criteria that differentiate maintainers and regainers via quantitative agreement.Design: The study used publicly available data from Look AHEAD (Action for Health in Diabetes; n = 1791) and Diabetes Prevention Program (DPP; n = 613) participants with ≥3% initial weight loss after lifestyle interventions and 4-y follow-up data...
December 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28936110/a-working-paradigm-for-the-treatment-of-obesity-in-gastrointestinal-practice
#13
Andres Acosta, Michael Camilleri
Obesity is a chronic, relapsing, multi-factorial disease characterized by abnormal or excessive adipose tissue accumulation that may impair health and increase disease risks. Despite the ever-increasing prevalence and economic and societal burden, the current approaches to treat obesity are not standardized or generally effective. In this manuscript, we describe a current working paradigm developed by a consensus approach for the multidisciplinary treatment of obesity in the GI practice. Obesity should be managed as a continuum of care focusing on weight loss, weight loss maintenance and prevention of weight regain...
January 2017: Techniques in Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28851944/therapeutic-effect-of-human-adipose-derived-stem-cells-and-their-secretome-in-experimental-diabetic-pain
#14
Anna T Brini, Giada Amodeo, Lorena M Ferreira, Anna Milani, Stefania Niada, Giorgia Moschetti, Silvia Franchi, Elisa Borsani, Luigi F Rodella, Alberto E Panerai, Paola Sacerdote
Painful neuropathy is one of the complications of diabetes mellitus that adversely affects patients'quality of life. Pharmacological treatments are not fully satisfactory, and novel approaches needed. In a preclinical mouse model of diabetes the effect of both human mesenchymal stromal cells from adipose tissue (hASC) and their conditioned medium (hASC-CM) was evaluated. Diabetes was induced by streptozotocin. After neuropathic hypersensitivity was established, mice were intravenously injected with either 1 × 10(6) hASC or with CM derived from 2 × 10(6) hASC...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28752380/comparison-of-banded-versus-non-banded-roux-en-y-gastric-bypass-a-series-of-1150-patients-at-a-single-institution
#15
Rena C Moon, Ashley Frommelt, Andre F Teixeira, Muhammad A Jawad
BACKGROUND: Variations have been proposed in order to improve weight loss and decrease complication profiles in Roux-en-Y gastric bypass (RYGB) patients. We previously reported a preliminary result of pericardial patch ring RYGB. We aim to report a detailed result of banded RYGB by comparing these patients to non-banded RYGB patients with larger case number and longer follow-up. MATERIAL AND METHODS: A retrospective chart review was performed in 543 banded RYGB and 607 non-banded RYGB patients who underwent laparoscopic RYGB between January 2009 and December 2014...
July 27, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28657838/reducing-calorie-intake-may-not-help-you-lose-body-weight
#16
David Benton, Hayley A Young
As the widespread availability of highly calorific food has resulted in a high incidence of obesity, attempts to decrease body weight have concentrated on trying to reduce energy intake. It is suggested that this is not the best approach. Although consuming more calories than expended is part of the initial problem, it does not follow that reducing intake, unless consciously counting calories, is the best solution. Mechanisms smooth out the large day-to-day differences in energy consumption, decreasing the importance of the size of a meal...
September 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28592990/predictors-of-successful-long-term-weight-loss-maintenance-a-two-year-follow-up
#17
Ryoko Sawamoto, Takehiro Nozaki, Tomoe Nishihara, Tomokazu Furukawa, Tomokazu Hata, Gen Komaki, Nobuyuki Sudo
BACKGROUND: Weight regain is a common problem following weight loss intervention, with most people who seek treatment for obesity able to lose weight, but few able to sustain the changes in behavior required to prevent subsequent weight regain. The identification of factors that predict which patients will successfully maintain weight loss or who are at risk of weight regain after weight loss intervention is necessary to improve the current weight maintenance strategies. The aim of the present study is identify factors associated with successful weight loss maintenance by women with overweight or obesity who completed group cognitive behavioral treatment (CBT) for weight loss...
2017: BioPsychoSocial Medicine
https://www.readbyqxmd.com/read/28465159/from-adolescence-to-young-adulthood-trajectories-of-psychosocial-health-following-roux-en-y-gastric-bypass
#18
Meg H Zeller, Emma C Pendery, Jennifer Reiter-Purtill, Sanita L Hunsaker, Todd M Jenkins, Michael A Helmrath, Thomas H Inge
BACKGROUND: Roux-en-Y gastric bypass (RYGB) in adolescence results in substantial bodyweight reduction and cardiometabolic benefits into young adulthood. Knowledge gaps remain in understanding psychosocial health. OBJECTIVE: Describe trajectories of weight and psychosocial health in adolescents who underwent RYGB into young adulthood. SETTING: Academic Pediatric Medical Center. METHODS: Fourteen adolescents (presurgery: mean body mass index = 59...
July 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28430045/laparoscopic-sleeve-gastrectomy-changes-in-the-last-decade-differences-in-morbidity-and-weight-loss
#19
Andrea Balla, Silvia Quaresima, Frida Leonetti, Emanuela Paone, Marco Brunori, Teresa Messina, Ardit Seitaj, Alessandro M Paganini
PURPOSE: Aim is to report the learning curve and standardization process of Laparoscopic Sleeve Gastrectomy (LSG), describing the evolution in surgical technique and patient management in the authors' experiences. METHODS: One hundred twenty-seven patients were divided in three Groups (A, B, and C), based on bougie size and technical details, and included 36, 46, and 45 patients, respectively. RESULTS: Mean operative time in Groups A, B, and C was 201...
November 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28386638/effect-of-diet-induced-weight-loss-on-lipoprotein-a-levels-in-obese-individuals-with-and-without-type-2-diabetes
#20
Kirsten A Berk, Reyhana Yahya, Adrie J M Verhoeven, Jeanette Touw, Frank P Leijten, Elisabeth F van Rossum, Vincent L Wester, Mirjam A Lips, Hanno Pijl, Reinier Timman, Gertraud Erhart, Florian Kronenberg, Jeanine E Roeters van Lennep, Eric J G Sijbrands, Monique T Mulder
AIMS/HYPOTHESIS: Elevated levels of lipoprotein(a) [Lp(a)] are an independent risk factor for cardiovascular disease (CVD), particularly in individuals with type 2 diabetes. Although weight loss improves conventional risk factors for CVD in type 2 diabetes, the effects on Lp(a) are unknown and may influence the long-term outcome of CVD after diet-induced weight loss. The aim of this clinical study was to determine the effect of diet-induced weight loss on Lp(a) levels in obese individuals with type 2 diabetes...
June 2017: Diabetologia
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