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Weight Loss Maintenance

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https://www.readbyqxmd.com/read/28546468/influence-of-maximal-fat-oxidation-on-long-term-weight-loss-maintenance-in-humans
#1
Sune Dandanell, Karina Husted, Signe Amdisen, Andreas Vigelsø, Flemming Dela, Steen Larsen, Jorn Wulff Helge
Impaired maximal fat oxidation has been linked to obesity and weight regain after weight loss. The aim was to investigate the relationship between maximal fat oxidation (MFO) and long-term weight loss maintenance. Eighty subjects (mean(SD)) (Age: 36(13) yrs; BMI: 38(1) kg/m(2)) were recruited from a total of 2420 former participants of an 11-12-week lifestyle intervention. Three groups were established based on % weight loss at follow-up (5.3(3.3) yrs): Clinical weight loss maintenance (CWL) >10% weight loss, moderate weight loss (MWL) 1-10%, and weight regain (WR)...
May 25, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28545688/quinacrine-in-endometrial-cancer-repurposing-an-old-antimalarial-drug
#2
Eleftheria Kalogera, Debarshi Roy, Ashwani Khurana, Susmita Mondal, Amy L Weaver, Xiaoping He, Sean C Dowdy, Viji Shridhar
OBJECTIVE: Generate preclinical data on the effect of quinacrine (QC) in inhibiting tumorigenesis in endometrial cancer (EC) in vitro and explore its role as an adjunct to standard chemotherapy in an EC mouse model. METHODS: Five different EC cell lines (Ishikawa, Hec-1B, KLE, ARK-2, and SPEC-2) representing different histologies, grades of EC, sensitivity to cisplatin and p53 status were used for the in vitro studies. MTT and colony formation assays were used to examine QC's ability to inhibit cell viability in vitro...
May 22, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28533672/effect-of-a-counseling-supported-treatment-with-the-mediterranean-diet-and-physical-activity-on-the-severity-of-the-non-alcoholic-fatty-liver-disease
#3
Chiara Gelli, Mirko Tarocchi, Ludovico Abenavoli, Laura Di Renzo, Andrea Galli, Antonino De Lorenzo
AIM: To determine the clinical effectiveness of nutritional counseling on reduction of non-alcoholic fatty liver disease (NAFLD) severity, weight loss, metabolic and anthropometric indexes and liver enzymes. METHODS: Forty-six adults with NAFLD received a 6-mo clinical and a dietary intervention (based on Mediterranean diet) carried out respectively by a gastroenterologist and a nutritionist with counseling license. The counseling process consisted of monthly meeting (about 45 min each)...
May 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28531583/consumption-of-dairy-products-and-weight-loss-maintenance
#4
Evangelia Avgeraki, Dimitra Zannidi, Evangelia Malakou, Eleni Karfopoulou, Konstantinos Anastasiou, Mary Yannakoulia
No abstract text is available yet for this article.
June 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28531581/meal-environment-and-successful-weight-loss-maintenance-the-medweight-study-results
#5
Dimitra Zannidi, Evangelia Avgeraki, Evangelia Malakou, Eleni Karfopoulou, Costas Anastasiou, Mary Yannakoulia
No abstract text is available yet for this article.
June 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28508330/mediators-of-weight-loss-maintenance-in-the-keep-it-off-trial
#6
A L Crain, N E Sherwood, B C Martinson, R W Jeffery
BACKGROUND: An important step toward enhancing the efficacy of weight loss maintenance interventions is identifying the pathways through which successful interventions such as the Keep It Off trial have worked. PURPOSE: This study aimed to assess the viability of mediated relationships between the Keep It Off Guided intervention, conceptually and empirically grounded potential mediators, and weight. Repeated measurement of mediators and weight enabled documentation of the temporal ordering of intervention delivery and changes in mediators and in weight among participants randomized to the Guided intervention or Self-Directed comparison group...
May 15, 2017: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/28507010/a-systematic-review-of-application-and-effectiveness-of-mhealth-interventions-for-obesity-and-diabetes-treatment-and-self-management
#7
REVIEW
Youfa Wang, Hong Xue, Yaqi Huang, Lili Huang, Dongsong Zhang
The use of mobile and wireless technologies and wearable devices for improving health care processes and outcomes (mHealth) is promising for health promotion among patients with chronic diseases such as obesity and diabetes. This study comprehensively examined published mHealth intervention studies for obesity and diabetes treatment and management to assess their effectiveness and provide recommendations for future research. We systematically searched PubMed for mHealth-related studies on diabetes and obesity treatment and management published during 2000-2016...
May 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/28497511/effects-of-medical-trainees-weight-loss-history-on-perceptions-of-patients-with-obesity
#8
Rebecca L Pearl, Dallas Argueso, Thomas A Wadden
CONTEXT: Medical professionals often express weight-biased attitudes. Prior research suggests that people who overcome a challenge are critical of individuals who struggle to overcome the same challenge. Thus, medical trainees who have successfully achieved and maintained weight loss may express greater weight bias and more critical attitudes toward patients with obesity who fail to overcome these challenges. OBJECTIVES: This study was designed to determine the effects of medical trainees' weight-loss history on weight-biased attitudes and responses to patients with varying weight-loss outcomes...
May 11, 2017: Medical Education
https://www.readbyqxmd.com/read/28496128/a-systems-genetics-approach-identified-gpd1l-and-its-molecular-mechanism-for-obesity-in-human-adipose-tissue
#9
Hao He, Dianjianyi Sun, Yong Zeng, Ruifeng Wang, Wei Zhu, Shaolong Cao, George A Bray, Wei Chen, Hui Shen, Frank M Sacks, Lu Qi, Hong-Wen Deng
To explore novel molecular mechanisms underlying obesity, we applied a systems genetics framework to integrate risk genetic loci from the largest body mass index (BMI) genome-wide association studies (GWAS) meta-analysis with mRNA and microRNA profiling in adipose tissue from 200 subjects. One module was identified to be most significantly associated with obesity and other metabolic traits. We identified eight hub genes which likely play important roles in obesity metabolism and identified microRNAs that significantly negatively correlated with hub genes...
May 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28490735/design-synthesis-and-biological-evaluation-of-novel-hedgehog-inhibitors-for-treating-pancreatic-cancer
#10
Vinod Kumar, Amit Kumar Chaudhary, Yuxiang Dong, Haizhen A Zhong, Goutam Mondal, Feng Lin, Virender Kumar, Ram I Mahato
Hedgehog (Hh) pathway is involved in epithelial-mesenchymal transition (EMT) and cancer stem cell (CSC) maintenance resulting in tumor progression. GDC-0449, an inhibitor of Hh pathway component smoothened (Smo) has shown promise in the treatment of various cancers including pancreatic cancer. However, the emergence of resistance during GDC-0449 treatment with numerous side effects limits its use. Therefore, here we report the design, synthesis and evaluation of novel GDC-0449 analogs using N-[3-(2-pyridinyl) phenyl] benzamide scaffold...
May 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28489160/nutritional-aspects-and-the-use-of-nutritional-supplements-by-women-who-underwent-gastric-bypass
#11
Elisangela Mara Trindade, Telma Souza E Silva Gebara, Maria Paula Carlini Cambi, Giorgio Alfredo Pedroso Baretta
Background: Bariatric surgery is deemed one of the most effective procedures for the treatment of obesity and it aims at the reduction and maintenance of weight loss in long term, as the control of the related comorbidities. Aim: Quantify the occurrence of alterations of the gastrointestinal tract, suggestive signs of nutritional deficiencies and the use of supplements in a group of women undergoing bariatric surgery. Methods: The sample consisted of women aged 20-65 years submitted to Roux-en-Y gastric bypass with monitoring equal to or higher than 24 months...
January 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/28484491/amino-acid-signatures-to-evaluate-the-beneficial-effects-of-weight-loss
#12
Nina Geidenstam, Martin Magnusson, Anders P H Danielsson, Robert E Gerszten, Thomas J Wang, Lovisa E Reinius, Hindrik Mulder, Olle Melander, Martin Ridderstråle
Aims. We investigated the relationship between circulating amino acid levels and obesity; to what extent weight loss followed by weight maintenance can correct amino acid abnormalities; and whether amino acids are related to weight loss. Methods. Amino acids associated with waist circumference (WC) and BMI were studied in 804 participants from the Malmö Diet and Cancer Cardiovascular Cohort (MDC-CC). Changes in amino acid levels were analyzed after weight loss and weight maintenance in 12 obese subjects and evaluated in a replication cohort (n = 83)...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28481266/inspection-and-reconstruction-of-metal-roof-deformation-under-wind-pressure-based-on-bend-sensors
#13
Liman Yang, Langfu Cui, Yunhua Li, Chao An
Metal roof sheathings are widely employed in large-span buildings because of their light weight, high strength and corrosion resistance. However, their severe working environment may lead to deformation, leakage and wind-lift, etc. Thus, predicting these damages in advance and taking maintenance measures accordingly has become important to avoid economic losses and personal injuries. Conventionally, the health monitoring of metal roofs mainly relies on manual inspection, which unavoidably compromises the working efficiency and cannot diagnose and predict possible failures in time...
May 6, 2017: Sensors
https://www.readbyqxmd.com/read/28481261/attenuating-the-biologic-drive-for-weight-regain-following-weight-loss-must-what-goes-down-always-go-back-up
#14
REVIEW
Christopher L Melby, Hunter L Paris, Rebecca M Foright, James Peth
Metabolic adaptations occur with weight loss that result in increased hunger with discordant simultaneous reductions in energy requirements-producing the so-called energy gap in which more energy is desired than is required. The increased hunger is associated with elevation of the orexigenic hormone ghrelin and decrements in anorexigenic hormones. The lower total daily energy expenditure with diet-induced weight loss results from (1) a disproportionately greater decrease in circulating leptin and resting metabolic rate (RMR) than would be predicted based on the decline in body mass, (2) decreased thermic effect of food (TEF), and (3) increased energy efficiency at work intensities characteristic of activities of daily living...
May 6, 2017: Nutrients
https://www.readbyqxmd.com/read/28480078/web-based-interventions-alone-or-supplemented-with-peer-led-support-or-professional-email-counseling-for-weight-loss-and-weight-maintenance-in-women-from-rural-communities-results-of-a-clinical-trial
#15
Patricia A Hageman, Carol H Pullen, Melody Hertzog, Bunny Pozehl, Christine Eisenhauer, Linda S Boeckner
Objective. This trial compared the effectiveness of a web-based only (WO) intervention with web-based supplemented by peer-led discussion (WD) or professional email counseling (WE) across 3 phases to achieve weight loss and weight maintenance in women from underserved rural communities. Methods. 301 women (BMI of 28-45 kg/m(2)) randomly assigned to groups participated in guided weight loss (baseline to 6 months), guided weight loss and maintenance (6 to 18 months), and self-managed weight maintenance (18 to 30 months)...
2017: Journal of Obesity
https://www.readbyqxmd.com/read/28476339/sleep-quality-is-associated-with-weight-loss-maintenance-status-the-medweight-study
#16
M Yannakoulia, C A Anastasiou, E Karfopoulou, A Pehlivanidis, D B Panagiotakos, A Vgontzas
Sleep duration and quality have been associated with many health outcomes, including weight management. We aimed to investigate the effect of self-reported sleep duration and quality on weight loss maintenance in participants of the MedWeight study, a registry of individuals that lost at least 10% of body weight in the past and either maintained the loss (maintainers: weight maintenance of at least 10% of initial weight loss) or regained it (regainers: weight ≥95% of their maximum body weight). Study participants included 528 volunteers (61% women)...
June 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28476118/-it-s-like-a-personal-motivator-that-you-carried-around-wi-you-utilising-self-determination-theory-to-understand-men-s-experiences-of-using-pedometers-to-increase-physical-activity-in-a-weight-management-programme
#17
Craig Donnachie, Sally Wyke, Nanette Mutrie, Kate Hunt
BACKGROUND: Self-monitoring using pedometers is an effective behaviour change technique to support increased physical activity (PA). However, the ways in which pedometers operate as motivational tools in adoption and maintenance of PA is not well understood. This paper investigates men's experiences of pedometers as motivational tools both during and after their participation in a 12-week group-based, weight management programme for overweight/obese men, Football Fans in Training (FFIT)...
May 5, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28476101/community-based-randomized-controlled-trial-of-diabetes-prevention-study-for-high-risk-individuals-of-type-2-diabetes-lifestyle-intervention-using-web-based-system
#18
Seon-Ah Cha, Sun-Young Lim, Kook-Rye Kim, Eun-Young Lee, Borami Kang, Yoon-Hee Choi, Kun-Ho Yoon, Yu-Bae Ahn, Jin-Hee Lee, Seung-Hyun Ko
BACKGROUND: The trend of increasing numbers of patients with type 2 diabetes emphasizes the need for active screening of high-risk individuals and intensive lifestyle modification (LSM). METHODS/DESIGN: The community-based Korean Diabetes Prevention Study (C-KDPS) is a randomized controlled clinical trial to prevent type 2 diabetes by intensive LSM using a web-based program. The two public healthcare centers in Korea are involved, and 420 subjects are being recruited for 6 months and will be followed up for 22 months...
May 5, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28475639/establishment-of-human-metastatic-colorectal-cancer-model-in-rabbit-liver-a-pilot-study
#19
Veronica Prieto, Johannes M Ludwig, Alton B Farris, Ganji Purnachandra Nagaraju, Taoreed O Lawal, Bassel El-Rayes, Hyun S Kim
RATIONALE AND OBJECTIVES: To develop a human metastatic colorectal cancer (mCRC) model in a rabbit liver. MATERIALS AND METHODS: Immunosuppression in 4 adult New Zealand White rabbits weighing 3.5 to 4.5 kg was induced with daily subcutaneous injection of 15 mg/kg Cyclosporine A (CsA). On day 3 open mini-laparotomy was performed and 0.2 ml (1.8x105 cells) suspension of HCT-116 and HT-29 human CRC cells were injected into the left and right medial lobe respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28475465/food-restriction-alters-salivary-cortisol-and-%C3%AE-amylase-responses-to-a-simulated-weightlifting-competition-without-significant-performance-modification
#20
Alexandre Durguerian, Edith Filaire, Catherine Drogou, Clément Bougard, Mounir Chennaoui
The aim of this investigation was to evaluate the effect of a 6-day food restriction period on the physiological responses and performance of 11 high-level weightlifters. After a period of weight maintenance (T2), they were assigned into two groups depending on whether they lost (Diet group, n = 6) or maintained their body weight (Control group, n = 5) during the course of those 6 days. An evaluation of performance and the measurement of salivary cortisol concentrations and salivary α-amylase (sAA) activity were performed during a simulated weightlifting competition which took place at T2, after a 6-day period of food restriction (T3)...
May 5, 2017: Journal of Sports Sciences
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