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head and neck cancer care

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https://www.readbyqxmd.com/read/28543939/symptom-appraisal-help-seeking-and-lay-consultancy-for-symptoms-of-head-and-neck-cancer
#1
J A Queenan, Benjamin Gottlieb, Deb Feldman-Stewart, Stephen Hall, Jonathan Irish, Patti Groome
BACKGROUND: Early diagnosis is important in head and neck cancer (HNC) patients in order to maximize the effectiveness of the treatments and minimize the debilitation associated with both the cancer and the invasive treatments of advanced disease. Many patients present with advanced disease, and there is little understanding as to why. This study investigated patients' symptom appraisal, help-seeking and lay-consultancy up to the time they first went to see a health care professional (HCP)...
May 23, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28535154/randomised-controlled-trial-of-early-prophylactic-feeding-vs-standard-care-in-patients-with-head-and-neck-cancer
#2
Teresa E Brown, Merrilyn D Banks, Brett G M Hughes, Charles Y Lin, Lizbeth M Kenny, Judith D Bauer
BACKGROUND: Weight loss remains significant in patients with head and neck cancer, despite prophylactic gastrostomy and intensive dietary counseling. The aim of this study was to improve outcomes utilising an early nutrition intervention. METHODS: Patients with head and neck cancer at a tertiary hospital in Australia referred for prophylactic gastrostomy prior to curative intent treatment were eligible for this single centre randomised controlled trial. Exclusions included severe malnutrition or dysphagia...
May 23, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28532439/efficacy-cost-utility-and-reach-of-an-ehealth-self-management-application-oncokompas-that-helps-cancer-survivors-to-obtain-optimal-supportive-care-study-protocol-for-a-randomised-controlled-trial
#3
Anja van der Hout, Cornelia F van Uden-Kraan, Birgit I Witte, Veerle M H Coupé, Femke Jansen, C René Leemans, Pim Cuijpers, Lonneke V van de Poll-Franse, Irma M Verdonck-de Leeuw
BACKGROUND: Cancer survivors have to deal with a wide range of physical symptoms, psychological, social and existential concerns, and lifestyle issues related to cancer and its treatment. Therefore, it is essential that they have access to optimal supportive care services. The eHealth self-management application Oncokompas was developed to support cancer survivors with where they need to turn to for advice and guidance, as well as to increase their knowledge on the availability of optimal support...
May 22, 2017: Trials
https://www.readbyqxmd.com/read/28527564/prospective-comparison-of-perioperative-antibiotic-management-protocols-in-oncological-head-and-neck-surgery
#4
Alexander K Bartella, Mohammad Kamal, Jan Teichmann, Anita Kloss-Brandstätter, Timm Steiner, Frank Hölzle, Bernd Lethaus
OBJECTIVES: The adequate perioperative antibiotic prophylaxis in head and neck cancer surgery is an important and easy applicable tool to decrease nosocomial morbidity and mortality by reducing the rate of infections. In the study a strictly perioperative antibiosis is compared with an extended postoperative prophylactic antibiosis. We aim to clarify the value of postoperative prophylactic antibiosis for the recovery and clinical course of patients. MATERIAL AND METHODS: In this prospective study 75 consecutive patients, who underwent major oncological head and neck surgery were included and divided in three groups, each containing 25 patients...
April 20, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28520896/laser-assisted-indocyanine-green-dye-angiography-for-postoperative-fistulas-after-salvage-laryngectomy
#5
Erin J Partington, Lindsay S Moore, Russel Kahmke, Jason M Warram, William Carroll, Eben L Rosenthal, Benjamin J Greene
Importance: Pharyngocutaneous fistula formation is an unfortunate complication after salvage laryngectomy for head and neck cancer that is difficult to anticipate and related to a variety of factors, including the viability of native pharyngeal mucosa. Objective: To examine whether noninvasive angiography with indocyanine green (ICG) dye can be used to evaluate native pharyngeal vascularity to anticipate pharyngocutaneous fistula development. Design, Setting, and Participants: This cohort study included 37 patients enrolled from June 1, 2013, to June 1, 2016, and follow-up was for at least 1 month postoperatively...
May 18, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28511705/pd-l1-expressing-circulating-tumour-cells-in-head-and-neck-cancers
#6
Arutha Kulasinghe, Chris Perry, Liz Kenny, Majid E Warkiani, Colleen Nelson, Chamindie Punyadeera
BACKGROUND: Blockade of the PD-1/PD-L1 immune checkpoint pathway is emerging as a promising immunotherapeutic approach for the management and treatment of head and neck cancer patients who do not respond to 1st/2nd line therapy. However, as checkpoint inhibitors are cost intensive, identifying patients who would most likely benefit from anti PD-L1 therapy is required. Developing a non-invasive technique would be of major benefit to the patient and to the health care system. CASE PRESENTATION: We report the case of a 56 year old man affected by a supraglottic squamous cell carcinoma (SCC)...
May 16, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28497009/false-positive-positron-emission-tomography-computed-tomography-scans-in-treated-head-and-neck-cancers
#7
Michael K Cheung, Shawn Y Ong, Uma Goyal, Betsy C Wertheim, Charles C Hsu, Sun K Yi
OBJECTIVE: Positron emission tomography/computed tomography (PET/CT) imaging for head and neck cancers (HNC) is commonly utilized for post-treatment assessment. Though PET/CT in this setting has been reported to have high negative predictive values (> 90%), positive predictive values have been reported at approximately 50%, leading to high rates of false positivity (FP) and troubling management decisions for both patient and practitioner. The objective of this study was to identify patient, disease, treatment and imaging factors that might be associated with a higher likelihood of FP on initial post-treatment PET/CT imaging for patients treated for HNC...
April 10, 2017: Curēus
https://www.readbyqxmd.com/read/28493196/head-and-neck-reconstruction-in-the-elderly-patient-a-safe-procedure
#8
Maximilian Reiter, Philipp Baumeister, Christian Jacobi
Demographic changes strongly affect industrialized countries. While free tissue transfer was initially believed to be beneficial only for younger patients, there is an increasing number of elderly patients requiring microvascular operations in our aging society. Medical and surgical risks for head and neck cancer patients over a certain age who undergo free tissue transfer has hardly been investigated. A retrospective mono-center cohort study was performed. All patients with the age 75 or higher undergoing microvascular operations were reviewed...
May 10, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28490940/systemic-therapy-in-the-curative-treatment-of-head-and-neck-squamous-cell-cancer-cancer-care-ontario-clinical-practice-guideline
#9
E Winquist, C Agbassi, B M Meyers, J Yoo, K K W Chan
OBJECTIVE: The aim of the present work was to make recommendations about the use of systemically administered drugs in combination or in sequence with radiation (rt) or surgery, or both, for cure or organ preservation, or both, in patients with locally advanced nonmetastatic (stages iii-ivb) squamous cell carcinoma of the head and neck (lascchn). METHODS: The Meta-analysis of Chemotherapy in Head and Neck Cancer (mach-nc) reports have, de facto, guided practice since 2000, and so we searched the literature for systematic reviews published from January 2000 to February 2015 in reference to five research questions...
April 2017: Current Oncology
https://www.readbyqxmd.com/read/28488375/factors-associated-with-healthcare-professional-s-rating-of-disfigurement-and-self-perceived-body-image-in-female-patients-with-head-and-neck-cancer
#10
S-C Chen, C-Y Huang, B-S Huang, C-Y Lin, K-H Fan, J T-C Chang, S-C Wu, Y-H Lai
The purpose of this study was to determine factors associated with self-perceived body image in female patients with head and neck cancer (HNC), and factors associated with healthcare professional's rating of disfigurement, as well as the correlation between patient and observer ratings. This cross-sectional study recruited 105 women with HNC at a large medical centre. Measures of facial disfigurement and body image, as well as demographic and clinical characteristics, were collected. Multivariate multiple linear regression modelling was used to identify factors associated with healthcare professional's rating of disfigurement and patient self-perceived body image...
May 9, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28485335/radical-chemo-irradiation-using-intensity-modulated-radiotherapy-for-locally-advanced-head-and-neck-cancer-in-elderly-patients-experience-from-a-tertiary-care-center-in-south-india
#11
J R Chalissery, P C Sudheeran, K M Varghese, K Venkatesan
OBJECTIVE: To assess the feasibility, tolerance and response of radical chemo irradiation using Intensity modulated Radiotherapy [IMRT] in elderly patients [age >65] with locally advanced head and neck cancer. MATERIAL AND METHODS: Patients aged 65 and above [range 65 to 84years] registered in oncology outpatient unit in our institution between December 2011 to 2014, with stage III and IV head and neck cancer were treated with radical dose of radiotherapy using IMRT and concurrent chemotherapy with cisplatin 40mg/sq...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28479935/the-role-of-dentistry-other-than-oral-care-in-patients-undergoing-radiotherapy-for-head-and-neck-cancer
#12
REVIEW
Hidenobu Matsuzaki, Kumiko Tanaka-Matsuzaki, Fuminobu Miyazaki, Hideki Aoyama, Hiroki Ihara, Norihisa Katayama, Kuniaki Katsui, Kengo Himei, Tetsuo Takeuchi, Tomoo Onoda, Yoshihiro Kimata, Jun-Ichi Asaumi
The usefulness of dental approaches, such as oral management, has gained recognition among patients treated for head and neck cancer. In particular, oral management plays a very important role before, during, and after treatment in patients undergoing radiotherapy, chemotherapy, or a combination of both. However, specialized dentistry knowledge and techniques that are useful for patients undergoing radiotherapy for head and neck cancer have yet to be reported. Therefore, in this review article, our aim is to introduce dental approaches in radiotherapy for patients with head and neck cancer that have been developed and are currently being used at our institute...
May 2017: Japanese Dental Science Review
https://www.readbyqxmd.com/read/28474488/a-q-methodology-study-to-investigate-the-experiences-of-head-and-neck-cancer-patients-from-diagnosis-to-1%C3%A2-year
#13
K J Reid, A Swift, H Mehanna
The experiences of disease and treatment for patients diagnosed with head and neck cancer (H&NC) are known to be important indicators of the quality of care but are represented poorly in the literature. Survival is a major outcome measure to which health-related quality of life (HRQoL) adds detail but outcomes are not fully representative of the patients' experiences because quality of care and reality of treatment are overlooked. This study explored the HRQoL, quality of care and reality of treatment themes using a mixed-methods approach, Q Methodology...
May 4, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28460212/outcome-of-head-and-neck-cancer-patients-who-did-not-receive-curative-intent-treatment
#14
Deegesh Shah, Gary R Hoffman
PURPOSE: There exists a subgroup of patients with head and neck cancer (HNC) who neither warrant nor request curative-intent treatment and who progress to a terminal-care paradigm. The purpose of this study was to determine the frequency of and reasons for an HNC terminal-care referral and the time to and place of death for such patients. MATERIALS AND METHODS: The authors undertook a retrospective cohort study of all attendees with HNC who had undergone multidisciplinary team (MDT) assessment at the Calvary Mater Hospital (Newcastle, Australia) from January 2013 through December 2014...
April 6, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28459393/physical-and-emotional-well-being-and-support-in-newly-diagnosed-head-and-neck-cancer-patient-caregiver-dyads
#15
Katherine R Sterba, Jane Zapka, Kent E Armeson, Keisuke Shirai, Amy Buchanan, Terry A Day, Anthony J Alberg
The purpose of this study was to characterize physical and emotional well-being and support in newly diagnosed head and neck (HNC) patients and caregivers and identify sociodemographic, clinical and behavioral risk factors for compromised well-being in patients, caregivers and dyads.. Newly diagnosed HNC patients and their primary caregivers (N = 72 dyads) completed questionnaires before treatment assessing physical and mental well-being, depression, cancer worry and open-ended support questions. We identified factors associated with compromised well-being in patients, caregivers and dyads...
May 1, 2017: Journal of Psychosocial Oncology
https://www.readbyqxmd.com/read/28456588/potential-for-low-value-palliative-care-of-patients-with-recurrent-head-and-neck-cancer
#16
REVIEW
Marci L Nilsen, Jonas T Johnson
Curative treatment for patients with advanced head and neck cancer can be associated with many side-effects, and many patients suffer from persistent treatment-related side-effects. Patients with recurrent cancer bear the burden of these effects along with additional symptoms attributed to the recurrent tumour. To better understand the benefits and burden of palliative treatments for patients with recurrent head and neck cancer, we reviewed the evidence on commonly used palliative treatments and their effect on quality of life...
April 26, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28455602/comparison-of-the-incidences-of-hyponatremia-in-adult-postoperative-critically-ill-patients-receiving-intravenous-maintenance-fluids-with-140%C3%A2-mmol-l-or-35%C3%A2-mmol-l-of-sodium-retrospective-before-after-observational-study
#17
Masako Okada, Moritoki Egi, Yuri Yokota, Naotaka Shirakawa, Daichi Fujimoto, Shinya Taguchi, Nana Furushima, Satoshi Mizobuchi
PURPOSE: The purpose of this study was to compare the incidences of hyponatremia in adult postoperative critically ill patients receiving isotonic and hypotonic maintenance fluids. METHODS: In this single-center retrospective before/after observational study, we included patients who had undergone an elective operation for esophageal cancer or for head and neck cancer and who received postoperative intensive care for >48 h from August 2014 to July 2016. In those patients, sodium-poor solution (35 mmol/L of sodium; Na35) had been administered as maintenance fluid until July 2015...
April 28, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28453605/outlier-practice-patterns-in-mohs-micrographic-surgery-defining-the-problem-and-a-proposed-solution
#18
Aravind Krishnan, Tim Xu, Susan Hutfless, Angela Park, Thomas Stasko, Allison T Vidimos, Barry Leshin, Brett M Coldiron, Richard G Bennett, Victor J Marks, Rebecca Brandt, Martin A Makary, John G Albertini
Importance: Outlier physician practices in health care can represent a significant burden to patients and the health system. Objective: To study outlier physician practices in Mohs micrographic surgery (MMS) and the associated factors. Design, Setting, and Participants: This retrospective analysis of publicly available Medicare Part B claims data from January 2012 to December 2014 includes all physicians who received Medicare payments for MMS from any practice performing MMS on the head and neck, genitalia, hands, and feet region of Medicare Part B patients...
April 28, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28449244/indications-and-extent-of-central-neck-dissection-for-papillary-thyroid-cancer-an-american-head-and-neck-society-consensus-statement
#19
Nishant Agrawal, Maria R Evasovich, Emad Kandil, Salem I Noureldine, Erin A Felger, Ralph P Tufano, Dennis H Kraus, Lisa A Orloff, Raymon Grogan, Peter Angelos, Brendan C Stack, Bryan McIver, Gregory W Randolph
BACKGROUND: The primary purposes of this interdisciplinary consensus statement were to review the relevant indications for central neck dissection (CND) in patients with papillary thyroid cancer (PTC) and to outline the appropriate extent and relevant techniques required to accomplish a safe and effective CND. METHODS: A writing group convened by the American Head and Neck Society (AHNS) Endocrine Committee was tasked with identifying the important clinical elements to consider when managing the central neck compartment in patients with PTC based on available evidence in the literature, and the group's collective experience...
April 27, 2017: Head & Neck
https://www.readbyqxmd.com/read/28449193/impact-of-metformin-on-patients-with-advanced-head-and-neck-cancer-undergoing-concurrent-chemoradiotherapy
#20
Pei-Hung Chang, Kun-Yun Yeh, Cheng-Hsu Wang, Eric Yen-Chao Chen, Shih-Wei Yang, Wen-Chi Chou, Jason Chia-Hsun Hsieh
BACKGROUND: The purpose of this study was to evaluate the impact of metformin on toxicities and survival in patients with head and neck cancer undergoing concurrent chemoradiotherapy (CRT). METHODS: We retrospectively analyzed and compared the clinical characteristics, treatment tolerance, toxicities, and survival of 252 patients with stages III, IVA, and IVB head and neck cancer undergoing concurrent CRT with and without metformin treatment between 2007 and 2010...
April 27, 2017: Head & Neck
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