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https://www.readbyqxmd.com/read/29337642/perineural-invasion-in-parotid-gland-malignancies
#1
Phillip Huyett, Umamaheswar Duvvuri, Robert L Ferris, Jonas T Johnson, Barry M Schaitkin, Seungwon Kim
Objectives To investigate the clinical predictors and survival implications of perineural invasion (PNI) in parotid gland malignancies. Study Design Case series with chart review. Setting Tertiary care medical center. Subjects and Methods Patients with parotid gland malignancies treated surgically from 2000 to 2015 were retrospectively identified in the Head and Neck Cancer Registry at a single institution. Data points were extracted from the medical record and original pathology reports. Results In total, 186 patients with parotid gland malignancies were identified with a mean follow-up of 5...
January 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29336226/identifying-metrics-before-and-after-readmission-following-head-and-neck-surgery-and-factors-affecting-readmission-rate
#2
Sidharth V Puram, Neil Bhattacharyya
Objectives Determine nationally representative readmission rates after head and neck cancer (HNCA) surgery and factors associated with readmission. Study Design Cross-sectional analysis of admissions database. Methods The 2013 Nationwide Readmissions Database was analyzed for HNCA surgery admissions and subsequent readmission within 30 days. The readmission rate, length of stay (LOS), disposition, mortality rate, and total charges were determined. Diagnoses and procedures upon readmission were quantified. Factors that were associated with readmission were determined...
January 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29324861/cost-of-treatment-for-head-and-neck-cancer-in-india
#3
Akashdeep Singh Chauhan, Shankar Prinja, Sushmita Ghoshal, Roshan Verma, Arun S Oinam
There are no published data on the cost of cancer treatment for guiding reimbursement decisions in India. The present study was designed to estimate the cost of treating head and neck cancer (HNC) with the aim of determining package rates. The present study was undertaken in the Departments of Radiotherapy and Otolaryngology of a large tertiary care hospital in North India. Economic health system costs incurred were assessed using a bottom-up methodology. Data on all resources-capital or recurrent, incurred on the delivery of HNC treatment were collected from April 2014 to March 2015...
2018: PloS One
https://www.readbyqxmd.com/read/29313134/the-effectiveness-of-zataria-extract-mouthwash-for-the-management-of-radiation-induced-oral-mucositis-in-patients-a-randomized-placebo-controlled-double-blind-study
#4
Azar Aghamohammadi, Daryush Moslemi, Jafar Akbari, Arash Ghasemi, Mohammad Azadbakht, Askari Asgharpour, Seyed Jalal Hosseinimehr
OBJECTIVES: Oral mucositis (OM) is a common debilitating complication of chemoradiotherapy treatment of head and neck cancers. This randomized placebo-controlled double-blind clinical trial study was performed to evaluate the effectiveness of Zataria multiflora (ZM) extract mouthwash in the prevention and reduction of OM related to local radiotherapy in the treatment of head and neck cancer patients. METHODS: Sixty-three patients with head and neck cancers, who underwent a conventional fractionated radiotherapy regimen, were entered into the study...
January 8, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29295635/real-world-utilization-of-molecular-diagnostic-testing-and-matched-drug-therapies-in-the-treatment-of-metastatic-cancers
#5
Anita Chawla, Miranda Peeples, Nanxin Li, Rachel Anhorn, Jason Ryan, James Signorovitch
AIMS: To assess the frequency of biopsies and molecular diagnostic testing (human DNA/RNA analysis), anti-cancer drug use (genomically-matched targeted therapy [GMTT], unmatched targeted therapy [UTT], endocrine therapy [ET], and chemotherapy [CT]), and medical service costs among adults with metastatic cancer. METHODS: Adults diagnosed with metastatic breast, non-small cell lung (NSCLC), colorectal, head and neck, ovarian, and uterine cancer (2010Q1-2015Q1) were identified in the OptumHealth Care Solutions claims database and followed from first metastatic diagnosis for ≥1 month and until end of data availability...
January 3, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29284926/a-clinicopathological-study-of-various-oral-cancer-diagnostic-techniques
#6
REVIEW
G Ulaganathan, K Thanvir Mohamed Niazi, Soundarya Srinivasan, V R Balaji, D Manikandan, K A Shahul Hameed, A Banumathi
Oral cancer is one of the most commonly occurring malignant tumors in the head and neck regions with high incident rate and mortality rate in the developed countries than in the developing countries. Generally, the survival rate of cancer patients may increase when diagnosed at early stage, followed by prompt treatment and therapy. Recently, cancer diagnosis and therapy design for a specific cancer patient have been performed with the advanced computer-aided techniques. The responses of the cancer therapy could be continuously monitored to ensure the effectiveness of the treatment process that hardly requires diagnostic result as quick as possible to improve the quality and patient care...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29282156/examining-cancer-survivorship-trajectories-exploring-the-intersection-between-qualitative-illness-narratives-and-quantitative-screening-instruments
#7
Chelsea Ratcliff, Aanand D Naik, Lindsey Ann Martin, Jennifer Moye
OBJECTIVE: This article examines the associations of quantitatively refined trajectories of adjustment to cancer survivorship determined by previously published qualitative narrative analysis. METHOD: Patients completed measures of cancer-related worry (Cancer Related Worries Scale), depression (Patient Health Questionnaire-9), posttraumatic growth (Benefit Finding Scale), and open-ended survey questions 6, 12, and 18 months postdiagnosis of head and neck, esophageal, gastric, or colorectal cancer...
December 28, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/29280802/1-5-ce-test-hours-oral-care-for-head-and-neck-cancer-symptom-management
#8
Emily Contrada
No abstract text is available yet for this article.
January 2018: American Journal of Nursing
https://www.readbyqxmd.com/read/29280639/clinical-use-of-metal-and-plastic-calipers-for-nutritional-assessment-of-patients-under-long-term-enteral-feeding-through-endoscopic-gastrostomy
#9
Ana Teresa Barata, Gonçalo Nunes, Carla Adriana Santos, Jorge Fonseca
BACKGROUND: Endoscopic gastrostomy (PEG) fed patients, including those with neurologic disorders (ND) or head and neck cancer (HNC) present high malnutrition risk and speech difficulties. Teams taking care of these patients need to rely on anthropometric data. Skinfold thickness (TSF) is used to assess nutritional status, but the use of heavy, large and expensive metal calipers may become a limitation. This study aimed to compare and correlate TSF measurements using a metal caliper and a plastic caliper in PEG fed patients...
November 14, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29276836/patient-reported-experiences-on-supportive-care-strategies-following-the-introduction-of-the-first-swedish-national-cancer-strategy-and-in-accordance-with-the-new-patient-act
#10
Bodil Westman, Lily Kirkpatrick, Fereshte Ebrahim, Roger Henriksson, Lena Sharp
INTRODUCTION: Several supportive care strategies are described in Swedish legislation and policy documents, such as the National Cancer Strategy and the Patient act. No previous systematic evaluation from a patient perspective has been performed. The aim of this study was to evaluate how these supportive care strategies are experienced by patients treated for cancer in the Stockholm-Gotland region. MATERIAL AND METHODS: In this cross-sectional study, we identified patients (diagnosed with gynaecological, haematological, upper gastrointestinal and head and neck cancer during 2014) from the Swedish Cancer Register...
December 25, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/29261835/comparison-of-tumor-classifications-for-cutaneous-squamous-cell-carcinoma-of-the-head-and-neck-in-the-7th-vs-8th-edition-of-the-ajcc-cancer-staging-manual
#11
Pritesh S Karia, Frederick C Morgan, Joseph A Califano, Chrysalyne D Schmults
Importance: Previous studies have shown that the AJCC Cancer Staging Manual, 7th edition (AJCC 7), tumor classification for cutaneous squamous cell carcinoma (CSCC) failed to accurately stratify disease-related outcomes. The recently released 8th edition (AJCC 8) features a revised tumor classification for only head and neck CSCC (HNCSCC). Objective: To compare AJCC 7 and AJCC 8 tumor classifications for HNCSCC and to validate AJCC 8. Design, Setting, and Participants: This was a 10-year retrospective cohort study (2000-2009) at an academic tertiary care center reviewing 680 primary HNCSCC tumors in 459 patients...
December 20, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/29251635/ce-oral-care-for-head-and-neck-cancer-symptom-management
#12
Laura Cullen, Sharon Baumler, Michele Farrington, Cindy Dawson, Peggy Folkmann, Loraine Brenner
Piloting an evidence-based practice change at a radiation oncology center. ABSTRACT: An evidence-based practice change at a radiation oncology center in a large academic medical center was designed to reduce the severity of oral mucositis in adults receiving radiation treatment for head and neck cancer. In the intervention described, patients were given newly created oral care kits and educational materials to improve their oral hygiene. Evaluations were conducted at three points during the project (before radiation treatment, during week 4 to 5 of treatment, and one month after treatment)...
December 14, 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/29251296/a-distress-thermometer-intervention-for-patients-with-head-and-neck-cancer%C3%A2
#13
Ingeborg C van der Meulen, Anne M May, Ron Koole, Wynand J G Ros
OBJECTIVES: To investigate the feasibility of an intervention using the National Comprehensive Cancer Network Distress Thermometer and Problem List with nurse-guided follow-up and the effect on depressive symptoms, health-related quality of life, and worry of cancer in patients with head and neck cancer.
. SAMPLE & SETTING: 110 patients with head and neck cancer in a two-arm randomized, controlled trial in an outpatient clinic of a university hospital. 
...
January 1, 2018: Oncology Nursing Forum
https://www.readbyqxmd.com/read/29247265/end-of-life-care-pathway-of-head-and-neck-cancer-patients-single-institution-experience
#14
T Heinonen, V Loimu, K Saarilahti, T Saarto, A Mäkitie
BACKGROUND: Studies on palliative care of head and neck cancer (HNC) patients are scarce although the affected patient population is quite large. OBJECTIVE: To evaluate the role of a specialised palliative-care pathway of HNC patients. PATIENTS AND METHODS: Data on all HNC patients who were treated at the Helsinki University Hospital Palliative Care Center during 1 year were retrospectively reviewed. The analysis comprised 60 patients (49 males; mean age 67 years; range 28-88)...
December 15, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29244985/malignancy-related-hypercalcemia-in-advanced-solid-tumors-survival-outcomes
#15
Ricardo Emanuel de Oliveira Ramos, Milena Perez Mak, Michel Fabiano Silva Alves, Gustavo Henrique Munhoz Piotto, Tiago Kenji Takahashi, Leonardo Gomes da Fonseca, Marina Cavalcanti Maroja Silvino, Paulo Marcelo Hoff, Gilberto de Castro
Purpose Malignancy-related hypercalcemia (MRH) is associated with a dismal prognosis. The widespread use of bisphosphonates (BPs), availability of more effective drugs in cancer treatment, and improvement in supportive care might have attenuated its impact. Patients and Methods To assess overall survival (OS) of patients with MRH in a contemporary setting, we conducted a retrospective analysis of 306 patients with solid cancer hospitalized for symptomatic hypercalcemia. A multivariable Cox proportional hazards regression model was performed to evaluate possible prognostic factors associated with MRH...
December 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/29244150/risk-and-prognostic-factors-for-multiple-primary-carcinomas-in-patients-with-head-and-neck-cancer
#16
Seiji Hosokawa, Goro Takahashi, Jun Okamura, Atsushi Imai, Daiki Mochizuki, Yoshinori Takizawa, Takashi Yamatodani, Kiyoshi Misawa, Hiroyuki Mineta
Background: Unexpected multiple primary carcinomas (MPCs) that develop in patients with head and neck carcinomas complicate approaches to their management. We therefore investigated the clinical factors associated with survival outcomes after the treatment of MPCs. Methods: We performed a retrospective review of records of 1104 patients who underwent treatment for primary head and neck carcinoma at Hamamatsu University Hospital. We evaluated clinical staging, age, sex, smoking, alcohol consumption, the primary tumor site (particularly the involvement of the mucosal epithelial lining of the aerodigestive tract), and overall survival (OS) as determined by Kaplan-Meier analysis...
December 13, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29240278/predictors-of-returns-to-the-emergency-department-after-head-and-neck-surgery
#17
R Michael Baskin, Jingnan Zhang, Carolyn Dirain, Paul Lipori, Gileno Fonseca, Raja Sawhney, Brian J Boyce, Natalie L Silver, Peter T Dziegielewski
BACKGROUND: Thirty-day hospital readmissions have become a measure of quality of care. Many readmissions enter through the emergency department. The purposes of this study were to determine the rate, risk factors, and costs of 30-day returns to the emergency department (30dEDRs) after head and neck surgery. METHODS: All adult patients undergoing head and neck surgery at the University of Florida from 2012 to 2014 were reviewed. Univariate and multivariate logistic regression analyses were performed to identify risk factors for 30dEDRs...
December 14, 2017: Head & Neck
https://www.readbyqxmd.com/read/29232825/galectin-1-inhibitor-otx008-induces-tumor-vessel-normalization-and-tumor-growth-inhibition-in-human-head-and-neck-squamous-cell-carcinoma-models
#18
Nathan A Koonce, Robert J Griffin, Ruud P M Dings
Galectin-1 is a hypoxia-regulated protein and a prognostic marker in head and neck squamous cell carcinomas (HNSCC). Here we assessed the ability of non-peptidic galectin-1 inhibitor OTX008 to improve tumor oxygenation levels via tumor vessel normalization as well as tumor growth inhibition in two human HNSCC tumor models, the human laryngeal squamous carcinoma SQ20B and the human epithelial type 2 HEp-2. Tumor-bearing mice were treated with OTX008, Anginex, or Avastin and oxygen levels were determined by fiber-optics and molecular marker pimonidazole binding...
December 9, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29232259/the-experience-of-head-and-neck-cancer-survivorship-including-laryngectomy-an-integrated-biopsychosocial-model
#19
Marlene C Jacobson
PURPOSE OF REVIEW: The head and neck cancer (HNC) survivorship experience is unique among cancer populations. This review seeks to explore the HNC survivor experience associated with altered upper aerodigestive tract (UADT) function using principles of survivorship. RECENT FINDINGS: HNC survivors experience complex physical, functional, and psychosocial challenges related to UADT dysfunction. Interventions need to address all of these dimensions being mindful of the survivor experience...
December 9, 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29229506/the-population-benefit-of-evidence-based-radiotherapy-5-year-local-control-and-overall-survival-benefits
#20
T P Hanna, J Shafiq, G P Delaney, S K Vinod, S R Thompson, M B Barton
BACKGROUND: To describe the population benefit of radiotherapy in a high-income setting if evidence-based guidelines were routinely followed. METHODS: Australian decision tree models were utilized. Radiotherapy alone (RT) benefit was defined as the absolute proportional benefit of radiotherapy compared with no treatment for radical indications, and of radiotherapy over surgery alone for adjuvant indications. Chemoradiotherapy (CRT) benefit was the absolute incremental benefit of concurrent chemoradiotherapy over RT...
December 8, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
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