Y Mahamat-Saleh, S Rinaldi, R Kaaks, C Biessy, E M Gonzalez-Gil, N Murphy, C Le Cornet, J M Huerta, S Sieri, A Tjønneland, L Mellemkjaer, M Guevara, K Overvad, A Perez-Cornago, S Tin Tin, L Padroni, V Simeon, G Masala, A May, E Monninkhof, S Christakoudi, A K Heath, K Tsilidis, A Agudo, M B Schulze, J Rothwell, C Cadeau, S Severi, E Weiderpass, M J Gunter, L Dossus
BACKGROUND: Excess body fatness and hyperinsulinemia are both associated with an increased risk of postmenopausal breast cancer. However, whether women with high body fatness but normal insulin levels or those with normal body fatness and high levels of insulin are at elevated risk of breast cancer is not known. We investigated the associations of metabolically defined body size and shape phenotypes with the risk of postmenopausal breast cancer in a nested case-control study within the European Prospective Investigation into Cancer and Nutrition...
April 25, 2023: Cancer Medicine