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https://www.readbyqxmd.com/read/29241276/multiband-mucosectomy-for-the-treatment-of-challenging-non-pedunculated-colorectal-polyps
#1
Joaquín Rodríguez-Sánchez, Eva De la Santa Belda, Pilar Olivencia Palomar, Margarita Úbeda Muñoz, José Olmedo Camacho
Background and study aims Endoscopic mucosal resection is the gold standard treatment for non-pedunculated colorectal polyps; however, some specific situations (location behind folds, scarred or flat morphology) can make this technique challenging. We aimed to assess the efficacy and safety of multiband mucosectomy (MBM) for resection of non-pedunculated colorectal polyps. Patients and methods This was a retrospective study of patients in whom MBM was performed to resect large non-pedunculated colorectal polyps...
December 14, 2017: Endoscopy
https://www.readbyqxmd.com/read/29241258/-changes-of-motor-balance-in-the-course-of-an-inpatient-psychosomatic-rehabilitation
#2
ElisabethJohanna Grub, Georg Wydra, Michael Käfer, Volker Köllner
Aim of the study For many rehabilitants both the motor balance and the feeling of being emotionally stable and in balance are essential preconditions for participation in employment and society. The goal of this study was to capture changes in motor balance in the course of an inpatient psychosomatic rehabilitation and to set them in relation to changes in mental variables. Methods 118 patients of a psychosomatic clinic (49.3±8.6 years; 75.4 % women) were examined at the beginning and the end of rehabilitation...
December 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/29241207/disease-remission-in-children-and-adolescents-with-intermediate-uveitis-a-survival-analysis
#3
Lara Borrego-Sanz, Lydia Abásolo, Consuelo López-Abad, Benjamín Fernández-Gutiérrez, Julián García-Feijoo, David Diaz-Valle, Esperanza Pato, Luis Rodriguez-Rodriguez
PURPOSE: To report the incidence rate (IR) of remission in pediatric noninfectious intermediate uveitis (IU). METHODS: Longitudinal retrospective cohort study, including 19 patients (32 eyes) between 1985 and 2014, followed-up until loss or January 2016. Remission was defined following the Standardization of Uveitis Nomenclature workshop criteria, prolonged remission as a remission spanning 12 months and until the end of follow-up, and relapse as recurrence of inflammatory activity in an eye in remission...
December 14, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/29241195/nursing-intervention-on-the-compliance-of-hemodialysis-patients-with-end-stage-renal-disease-a-meta-analysis
#4
Jing Wang, Peng Yue, Jing Huang, Xiaodong Xie, Yunhua Ling, Li Jia, Yunjin Xiong, Fang Sun
BACKGROUND: Dialysis is imperative for patients with end-stage renal disease (ESRD); however, compliance ensures its efficacy. Nursing intervention has been considered to improve compliance. This meta-analysis is aimed at exploring the effects of nursing intervention on dialysis compliance. METHODS: A search was performed in the PubMed, Cochrane, and Embase databases for relevant original research articles. Studies were included or excluded based on the simultaneous consideration of quality as ranked by Jadad score and the compliance with predefined selection criteria...
December 12, 2017: Blood Purification
https://www.readbyqxmd.com/read/29241193/comparative-analysis-on-low-and-standard-dose-regimes-of-alteplase-thrombolytic-therapy-for-acute-ischemic-stroke-efficacy-and-safety
#5
Guangjian Zhao, Tingfen Huang, Mei Zheng, Yansen Cui, Yunyong Liu, Zhongrong Cheng, Ziran Wang
OBJECTIVE: This study analyzed the efficacy and safety of low-dose and standard-dose alteplase intravenous thrombolytic therapy for acute ischemic stroke (AIS). METHODS: Patients with AIS who underwent intravenous alteplase thrombolysis from July 2012 to December 2016 were retrospectively analyzed and correspondingly divided into low-dose (0.6-0.89 mg/kg) group and standard-dose group (0.9 mg/kg) according to alteplase dosage. The clinical outcome was evaluated by modified Rankin Scale (mRS) at 90 days after onset...
December 14, 2017: European Neurology
https://www.readbyqxmd.com/read/29241172/neurophysiological-monitoring-and-awake-craniotomy-for-resection-of-intracranial-gliomas
#6
Taiichi Saito, Manabu Tamura, Mikhail F Chernov, Soko Ikuta, Yoshihiro Muragaki, Takashi Maruyama
Aggressive resection of intracranial gliomas has a positive impact on patients' prognosis, but is associated with a risk of neurological complications. For preservation of brain functions and avoidance of major postoperative morbidity various methods of intraoperative neurophysiological monitoring have been introduced into clinical practice. At present, somatosensory evoked potentials (SSEP), motor evoked potentials (MEP), visual evoked potentials (VEP), brainstem auditory evoked potentials (BAEP), and electrocorticography (ECoG) are used routinely during neurosurgical procedures...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29241084/neoadjuvant-radiotherapy-combined-with-capecitabine-and-sorafenib-in-patients-with-advanced-kras-mutated-rectal-cancer-a-phase-i-ii-trial-sakk-41-08
#7
Roger von Moos, Dieter Koeberle, Sabina Schacher, Stefanie Hayoz, Ralph C Winterhalder, Arnaud Roth, György Bodoky, Panagiotis Samaras, Martin D Berger, Daniel Rauch, Piercarlo Saletti, Ludwig Plasswilm, Daniel Zwahlen, Urs R Meier, Pu Yan, Paola Izzo, Dirk Klingbiel, Daniela Bärtschi, Kathrin Zaugg
BACKGROUND: KRAS mutation occurs in ∼40% of locally advanced rectal cancers (LARCs). The multitarget tyrosine kinase inhibitor sorafenib has radiosensitising effects and might improve outcomes for standard preoperative chemoradiotherapy in patients with KRAS-mutated LARC. METHODS: Adult patients with KRAS-mutated T3/4 and/or N1/2M0 LARC were included in this phase I/II study. The phase I dose-escalation study of capecitabine plus sorafenib and radiotherapy was followed by a phase II study assessing efficacy and safety...
December 11, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/29241083/a-review-of-the-value-of-human-epidermal-growth-factor-receptor-2-her2-targeted-therapies-in-breast-cancer
#8
REVIEW
N A Nixon, M B Hannouf, S Verma
The cost of cancer drugs continues to escalate with the rapid development and approval of novel therapies, especially over the course of the last decade. In human epidermal growth factor receptor 2 (HER2)-positive breast cancer, the survival benefits gained by new treatments have been undeniably substantial. It is important to assess the financial value of these therapies for decision making at both the societal and individual level. This information is key for managing resources in resource-limited health care systems, while at the same time supporting patient decision-making and conversations between patient and physicians on cost versus benefit...
December 10, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/29240959/evaluation-of-left-ventricular-function-in-overweight-children-and-teenagers-with-arterial-hypertension-and-white-coat-hypertension
#9
Tomasz Florianczyk, Malgorzata Golabek-Dylewska, Beata Kucinska, Bozena Werner
BACKGROUND: Obesity in childhood is strongly associated with elevated arterial blood pressure and risk of hypertension. The aim of the study was the evaluation of left ventricular function in hypertensive and white coat hypertensive overweight children and teenagers. METHODS: The study group consisted of 74 overweight patients aged 10.3 ± 3.1 years (range: 6-16 years) diagnosed as hypertensive in standard blood pressure measurement. The control group consisted of 31 normotensive and normoweight children...
December 14, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/29240786/time-trend-analysis-2009-2016-of-antimicrobial-susceptibility-in-neisseria-gonorrhoeae-isolated-in-italy-following-the-introduction-of-the-combined-antimicrobial-therapy
#10
Paola Stefanelli, Maria Fenicia Vescio, Maria Paola Landini, Ivano Dal Conte, Alberto Matteelli, Antonio Cristaudo, Marina Gaino, Marco Cusini, Anna Maria Barbui, Antonella Mencacci, Rosella De Nittis, Valeria Ghisetti, Elena Stroppiana, Anna Carannante
INTRODUCTION: Neisseria gonorrhoeae (NG) antimicrobial susceptibility trends to azithromycin, cefixime and ceftriaxone were analyzed, from 2009 to 2016, to monitor changing antimicrobial susceptibility concomitant with the change in prescribing practice in 2012 from cefixime, or ceftriaxone, to ceftriaxone plus azithromycin. Patient characteristics predictive to be infected by antibiotic resistant N. gonorrhoeae were estimated. Finally, the protocol for the treatment of gonorrhoea, in comparison with the international guidelines, was also evaluated...
2017: PloS One
https://www.readbyqxmd.com/read/29240658/nursing-activities-for-patients-with-chronic-disease-in-primary-care-settings-a-practice-analysis
#11
Marie-Eve Poitras, Maud-Christine Chouinard, Frances Gallagher, Martin Fortin
BACKGROUND: Nurses in primary care organizations play a central role for patients with chronic disease. Lack of clarity in role description may be associated with underutilization of nurse competencies that could benefit the growing population of patients with chronic disease. OBJECTIVE: The purpose of the research was to describe nursing activities in primary care settings with patients with chronic disease. METHODS: A Web-based survey was sent to nurses practicing in Family Medicine Groups in the Canadian Province of Québec...
January 2018: Nursing Research
https://www.readbyqxmd.com/read/29240639/absorbable-antibiotic-beads-prophylaxis-in-immediate-breast-reconstruction
#12
Denise M Kenna, Busayo Irojah, Kimber Lee Mudge, Kendra Eveler
BACKGROUND: Breast reconstruction with tissue expander is the most common mode of reconstruction following mastectomy. Infection necessitating tissue expander removal is a significant complication leading to patient distress as well as increased health care costs. METHODS: Over 3 years, 127 breast reconstructions with tissue expanders were performed by a single surgeon. Fifty-nine of these reconstructions were performed using a standardized protocol in which patients washed with chlorhexidine several days prior to surgery and received intravenous antibiotics preoperatively...
December 13, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29240630/in-vitro-characterization-of-the-pittsburgh-pediatric-ambulatory-lung
#13
Ryan A Orizondo, Alexandra G May, Shalv P Madhani, Brian J Frankowski, Greg W Burgreen, Peter D Wearden, William J Federspiel
Acute and chronic respiratory failure are a significant source of pediatric morbidity and mortality. Current respiratory support options used to bridge children to lung recovery or transplantation typically render them bedridden and can worsen long-term patient outcomes. The Pittsburgh Pediatric Ambulatory Lung (P-PAL) is a wearable pediatric blood pump and oxygenator (0.3 m surface area) integrated into a single compact unit that enables patient ambulation. The P-PAL is intended for long-term use and designed to provide up to 90% of respiratory support in children weighing 5-25 kg...
December 11, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29240600/meibomian-gland-performance-in-glaucomatous-patients-with-long-term-instillation-of-iop-lowering-medications
#14
Wan-Hua Cho, Ing-Chou Lai, Po-Chiung Fang, Chun-Chih Chien, Shin-Ling Tseng, Yu-Hsuan Lai, Yu-Ting Huang, Ming-Tse Kuo
PURPOSE: To investigate the meibomian gland (MG) performance in patients with glaucoma under topical intraocular pressure (IOP)-lowering medications. METHODS: This was a cross-sectional case-control study. Patients with glaucoma under different dosages and instillation periods of topical IOP-lowering medications were included. A total of 30 eyes out of 30 healthy participants and 85 eyes out of 85 patients with glaucoma were analyzed. The burden of instilling anti-glaucoma agents (BAG) was simply scored for each participant based on the number, formula, frequency, and duration of topical IOP-lowering medications used...
December 13, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29240569/paediatric-procedural-sedation-and-analgesia-by-emergency-physicians-in-a-country-with-a-recent-establishment-of-emergency-medicine
#15
Maybritt I Kuypers, Gaël J P Smits, Eva P Baerends, Erick Oskam, Eef P J Reijners, Lisette A A Mignot-Evers, Wendy A M H Thijssen, Frans B Plötz, Erik H M Korsten
OBJECTIVES: Paediatric patients receive less procedural sedation and analgesia (PSA) in the emergency department compared with adults, especially in countries where emergency medicine is at an early stage of development. The objectives of this study were to evaluate the adverse events and efficacy of paediatric PSA in a country with a recent establishment of emergency medicine and to describe which factors aided implementation. METHODS: This is a prospective, multicentre, observational study of paediatric patients undergoing PSA by the first trained emergency physicians (EPs) in The Netherlands...
December 13, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/29240251/progenitor-cells-from-different-zones-of-human-cartilage-and-their-correlation-with-histopathological-osteoarthritis-progression
#16
V P Mantripragada, W A Bova, C Boehm, N S Piuzzi, N A Obuchowski, R J Midura, G F Muschler
Cell-based therapies development for the treatment of osteoarthritis (OA) requires an understanding of the disease progression and attributes of the cells resident in cartilage. This study focused on quantitative assessment of the concentration and biological potential of stem and progenitor cells resident in different zones of cartilage displaying macroscopic Outerbridge grade 1-2 OA, and their correlation with OA progression based on established histologic scoring system. Lateral femoral condyles were collected from fifteen patients with idiopathic OA and varus knees undergoing total knee arthroplasty...
December 14, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29240247/do-we-still-need-oral-food-challenges-for-the-diagnosis-of-food-allergy
#17
REVIEW
Philippe A Eigenmann
Food challenges are standard in the diagnosis in patients suspected of being allergic to food. However, their role is regularly questioned due to the time required to perform them, and to their cost and the inherent risk of severe reactions. Food challenges have been challenged by recent advances defining threshold values for food-specific IgE helping to predict the probability of having symptoms to the suspected food. Also, identification of major allergens to various highly allergenic foods such as peanuts or tree nuts have contributed to an increased accuracy of IgE testing...
December 14, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29240126/analysis-of-long-term-visual-quality-with-numerical-3d-ray-tracing-after-corneal-crosslinking-treatment
#18
Staffan Schedin, Per Hallberg, Anders Behndig
A numerical 3D ray tracing model was used to evaluate the long-term visual effects of two regimens of corneal crosslinking (CXL) treatment of 48 patients with the corneal degeneration keratoconus. The 3D ray tracing analyses were based on corneal elevation data measured by Scheimpflug photography. Twenty-two patients were treated with standard CXL applied uniformly across the corneal surface, whereas 26 patients underwent a customized, refined treatment only at local zones on the cornea (photorefractive intrastromal CXL; PiXL)...
December 10, 2017: Applied Optics
https://www.readbyqxmd.com/read/29240005/efficacy-of-a-dual-ring-wound-protector-for-prevention-of-surgical-site-infections-after-pancreaticoduodenectomy-in-patients-with-intrabiliary-stents-a-randomized-clinical-trial
#19
Alexsander K Bressan, Jean-Michel Aubin, Guillaume Martel, Elijah Dixon, Oliver F Bathe, Francis R Sutherland, Fady Balaa, Richard Mimeault, Janet P Edwards, Sean C Grondin, Susan Isherwood, Keith D Lillemoe, Sara Saeed, Chad G Ball
OBJECTIVE: To evaluate the efficacy of a dual-ring wound protector for preventing incisional surgical site infection (SSI) among patients with preoperative biliary stents undergoing pancreaticoduodenectomy (PD). METHODS AND ANALYSIS: This study was a parallel, dual-arm, double-blind randomized controlled trial. Adult patients with a biliary stent undergoing elective PD at 2 tertiary care institutions were included (February 2013 to May 2016). Patients were randomly assigned to receive a surgical dual-ring wound protector or no wound protector, and also the current standard of care...
December 12, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29239999/care-management-to-reduce-disparities-and-control-hypertension-in-primary-care-a-cost-effectiveness-analysis
#20
Jonathan C Hong, William V Padula, Ilene L Hollin, Tanvir Hussain, Katherine B Dietz, Jennifer P Halbert, Jill A Marsteller, Lisa A Cooper
BACKGROUND: Project ReD CHiP (reducing disparities and controlling hypertension in primary care) care management was a clinic-based intervention that aimed to improve blood pressure control through improved care coordination and provide self-management support to patients from racially and socioeconomically. OBJECTIVE: To evaluate the cost-effectiveness of ReD CHiP care management versus standard care to treat hypertension in diverse communities. RESEARCH DESIGN: Microsimulation model from a health care sector perspective over 15 years...
December 12, 2017: Medical Care
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