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https://www.readbyqxmd.com/read/29054834/evaluation-of-web-based-continuing-professional-development-courses-aggregate-mixed-methods-model
#1
Arezoo Ebn Ahmady, Megan Barker, Myra Fahim, Rosa Dragonetti, Peter Selby
BACKGROUND: Many continuing professional development (CPD) Web-based programs are not explicit about underlying theory and fail to demonstrate impact. OBJECTIVE: The aim of this study was to develop and apply an aggregate mixed-methods evaluation model to describe the paradigm, theoretical framework, and methodological approaches used to evaluate a CPD course in tobacco dependence treatment, the Training Enhancement in Applied Cessation Counseling and Health (TEACH) project...
October 20, 2017: JMIR Medical Education
https://www.readbyqxmd.com/read/29054351/low-incidence-of-bone-health-presentations-at-national-hand-meetings
#2
Daniel L Christensen, Kyle E Nappo, Benjamin Ficke, Scott M Tintle
PURPOSE: The purpose of this study was to determine the frequency with which osteoporosis topics (screening, medical treatment, and fracture prevention) are presented at national hand surgery meetings. This was compared with the frequency of the same topics presented at the Orthopaedic Trauma Association (OTA) annual meetings. METHODS: The annual meeting programs for the American Society for Surgery of the Hand (ASSH), the American Association for Hand Surgery (AAHS), and the OTA from the previous 10 years (2007-2016) were searched for presentations that covered bone health at each of these meetings...
October 18, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29054036/snava-a-real-time-multi-fpga-multi-model-spiking-neural-network-simulation-architecture
#3
Athul Sripad, Giovanny Sanchez, Mireya Zapata, Vito Pirrone, Taho Dorta, Salvatore Cambria, Albert Marti, Karthikeyan Krishnamourthy, Jordi Madrenas
Spiking Neural Networks (SNN) for Versatile Applications (SNAVA) simulation platform is a scalable and programmable parallel architecture that supports real-time, large-scale, multi-model SNN computation. This parallel architecture is implemented in modern Field-Programmable Gate Arrays (FPGAs) devices to provide high performance execution and flexibility to support large-scale SNN models. Flexibility is defined in terms of programmability, which allows easy synapse and neuron implementation. This has been achieved by using a special-purpose Processing Elements (PEs) for computing SNNs, and analyzing and customizing the instruction set according to the processing needs to achieve maximum performance with minimum resources...
October 5, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/29053780/reaching-and-grasping-actions-and-their-context-shape-the-perception-of-object-size
#4
Annalisa Bosco, Fabio Daniele, Patrizia Fattori
Humans frequently estimate the size of objects to grasp them. In fact, when performing an action, our perception is focused towards the visual properties of the object that enable us to successfully execute the action. However, the motor system is also able to influence perception, but only a few studies have reported evidence for action-induced visual perception modifications. Here, we aimed to look for a feature-specific perceptual modulation before and after a reaching or a grasping action. Human participants were instructed to either reach for or grasp two-dimensional bars of different size and to perform a size perceptual task before and after the action in two contexts: in one where they knew the subsequent type of movement and in the other where they did not know...
October 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/29053544/the-correlation-between-the-ota-ao-classification-system-and-compartment-syndrome-in-both-bone-forearm-fractures
#5
Thomas S Auld, John S Hwang, Nicholas Stekas, Peter D Gibson, Michael S Sirkin, Mark C Reilly, Mark R Adams
OBJECTIVE: To evaluate the efficacy of using the Orthopaedic Trauma Association (OTA/AO) classification for both bone forearm fractures in predicting compartment syndrome. DESIGN: Retrospective cohort. SETTING: Level 1 Academic Trauma Center. PATIENTS/PARTICIPANTS: One hundred fifty-one patients 18 years of age and older, with both bone forearm fractures diagnosed from 2001 to 2016 were categorized based on the OTA/AO classification...
November 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29053543/decreased-time-to-antibiotic-prophylaxis-for-open-fractures-at-a-level-one-trauma-center
#6
Joey P Johnson, Avi D Goodman, Adam M Haag, Roman A Hayda
OBJECTIVE: To determine whether time to administration of antibiotics decreased after the implementation of an open fracture working group and antibiotic prophylaxis protocol. DESIGN: Retrospective cohort study. SETTING: One Level 1 Trauma Center. PATIENTS: Patients 18 years of age and older who sustained an open fracture and presented directly to our emergency department. INTERVENTION: Prompt irrigation and debridement in the operating room and fracture stabilization dictated by the treating surgeon...
November 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29052905/metabolic-changes-in-patients-with-prostate-cancer-during-androgen-deprivation-therapy
#7
REVIEW
Koji Mitsuzuka, Yoichi Arai
Androgen deprivation therapy continues to be widely used for the treatment of prostate cancer despite the appearance of new-generation androgen-receptor targeting drugs after 2000. Androgen deprivation therapy can alleviate symptoms in patients with metastatic prostate cancer and might have a survival benefit in some patients, but it causes undesirable changes in lipid, glucose, muscle or bone metabolism. These metabolic changes could lead to new onset or worsening of diseases, such as obesity, metabolic syndrome, diabetes mellitus, cardiovascular disease, sarcopenia or fracture...
October 20, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29052758/effects-of-trying-not-to-move-instruction-on-cortical-load-and-concurrent-cognitive-performance
#8
Christine Langhanns, Hermann Müller
Motor and cognitive tasks often interfere when performed concurrently. The amount of interference typically scales with difficulty of the tasks involved. Thus, supposedly 'easy' motor tasks with restricted movement amplitude, like sitting on a chair, should show little or no interference with cognitive tasks at all. We measured the processing load induced by different postural tasks and their effect on cognitive performance under cognitive-motor dual-task conditions. Sixteen subjects performed postural motor tasks in three different positions: 'Lying in a sun lounger', 'Sitting on a bike saddle', and 'Upright on feet'...
October 20, 2017: Psychological Research
https://www.readbyqxmd.com/read/29052666/patients-perspectives-of-engagement-as-a-safety-strategy
#9
Chasity Burrows Walters, Elizabeth A Duthie
PURPOSE/OBJECTIVES: To describe patient engagement as a safety strategy from the perspective of hospitalized surgical patients with cancer.
. RESEARCH APPROACH: Qualitative, descriptive approach using grounded theory.
. SETTING: Memorial Sloan Kettering Cancer Center in New York, New York.
. PARTICIPANTS: 13 hospitalized surgical patients with cancer.
. METHODOLOGIC APPROACH: Grounded theory with maximum variation sampling...
November 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/29052661/adherence-and-coping-strategies-in-outpatients-with-chronic-myeloid-leukemia-receiving-oral-tyrosine-kinase-inhibitors
#10
Jochen Hefner, Eva-Johanna Csef, Volker Kunzmann
PURPOSE/OBJECTIVES: To assess adherence and coping strategies in outpatients with chronic myeloid leukemia (CML) on oral tyrosine kinase inhibitors (TKIs).
. DESIGN: Prospective, descriptive.
. SETTING: An interdisciplinary oncology outpatient clinic in Germany.
. SAMPLE: 35 outpatients with CML on oral TKIs.
. METHODS: Adherence and coping strategies were assessed with questionnaires. Clinical data were extracted from medical charts...
November 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/29052604/effect-of-topical-loteprednol-etabonate-with-lid-hygiene-on-tear-cytokines-and-meibomian-gland-dysfunction-in-prosthetic-eye-wearers
#11
J S Ko, Y Seo, M K Chae, S Y Jang, J S Yoon
PurposeTo assess tear cytokine levels and clinical outcomes in meibomian gland dysfunction (MGD) in the blind eye of patients wearing an ocular prosthesis after 2 months of treatment with topical loteprednol etabonate and eyelid scrubs with warm compresses.Patients and methodsThis study included patients with MGD wearing a unilateral ocular prosthesis for more than 1 year. All patients topically received 0.5% loteprednol etabonate and were instructed to scrub their eyelids with warm compresses on the prosthetic eye for 2 months...
October 20, 2017: Eye
https://www.readbyqxmd.com/read/29052571/susceptibility-weighted-imaging-in-thrombolytic-therapy-of-acute-ischemic-stroke
#12
REVIEW
Lin Li, Ming-Su Liu, Guang-Qin Li, Yang Zheng, Tong-Li Guo, Xin Kang, Mao-Ting Yuan
OBJECTIVE: To provide a comprehensive and latest overview of susceptibility-weighted imaging (SWI) in the application of thrombolysis in acute ischemic stroke, and to update the decision-making effect and clinical value of SWI on identifying stroke patients suitable for thrombolytic therapy and possible benefits and risks followed. DATA SOURCES: Literatures referred to this review were collected from PubMed, Medline, and EMBASE published till May 2017, using the search terms including susceptibility-weighted imaging, gradient-echo, T2*, thrombolysis, recombinant tissue plasminogen activator (rt-PA), thrombolytic therapy, and stroke...
October 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/29052193/identification-of-open-chromatin-regions-in-plant-genomes-using-atac-seq
#13
Marko Bajic, Kelsey A Maher, Roger B Deal
Identifying and characterizing highly accessible chromatin regions assists in determining the location of genomic regulatory elements and understanding transcriptional regulation. In this chapter, we describe an approach to map accessible chromatin features in plants using the Assay for Transposase-Accessible Chromatin, combined with high-throughput sequencing (ATAC-seq), which was originally developed for cultured animal cells. This technique utilizes a hyperactive Tn5 transposase to cause DNA cleavage and simultaneous insertion of sequencing adapters into open chromatin regions of the input nuclei...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29051814/using-4-to-grade-near-normal-muscle-strength-does-not-improve-agreement
#14
Søren O'Neill, Sofie Louise Thomsen Jaszczak, Anne Katrine Søndergaard Steffensen, Birgit Debrabant
BACKGROUND: Manual assessment of muscle strength is often graded using the ordinal Medical Research Council (MRC) scale. The scale has a number of inherent weaknesses, including poorly defined limits between grades '4' and '5' and very large differences in the span of muscle strength encompassed by each of the six grades. It is not necessarily obvious how to convert a manual muscle test finding into an MRC grade. Several modifications which include intermediate grades have been suggested to improve the MRC scale and the current study examines whether agreement improves and variation in ratings decrease, with an intermediate grade between '4' and '5', in circumstances where such a grade would seem appropriate...
2017: Chiropractic & Manual Therapies
https://www.readbyqxmd.com/read/29051703/buprenorphine-naloxone-maintenance-therapy-an-observational-retrospective-report-on-the-effect-of-dose-on-18%C3%A2-months-retention-in-an-office-based-treatment-program
#15
Theodore V Parran, A G Mace, Yael J Dahan, Christopher A Adelman, Mykola Kolganov
CONTEXT AND OBJECTIVE: Buprenorphine has been available with few reports of the dose range necessary to adequately maintain patients. We report on the effect of 8 mg/d versus 16 mg/d of buprenorphine on long-term patient retention in office-based opioid maintenance (OBOMT). DESIGN SETTING AND PARTICIPANTS: Case series, at an urban hospital-based primary care clinic providing OBOMT to 157 opiate-dependent, low socioeconomic status, uninsured, nonhomeless patients...
2017: Substance Abuse: Research and Treatment
https://www.readbyqxmd.com/read/29051690/better-together-simultaneous-presentation-of-speech-and-gesture-in-math-instruction-supports-generalization-and-retention
#16
Eliza L Congdon, Miriam A Novack, Neon Brooks, Naureen Hemani-Lopez, Lucy O'Keefe, Susan Goldin-Meadow
When teachers gesture during instruction, children retain and generalize what they are taught (Goldin-Meadow, 2014). But why does gesture have such a powerful effect on learning? Previous research shows that children learn most from a math lesson when teachers present one problem-solving strategy in speech while simultaneously presenting a different, but complementary, strategy in gesture (Singer & Goldin-Meadow, 2005). One possibility is that gesture is powerful in this context because it presents information simultaneously with speech...
August 2017: Learning and Instruction
https://www.readbyqxmd.com/read/29051496/evidence-for-a-task-dependent-switch-in-subthalamo-nigral-basal-ganglia-signaling
#17
Jay J Jantz, Masayuki Watanabe, Ron Levy, Douglas P Munoz
Basal ganglia (BG) can either facilitate or inhibit movement through excitatory and inhibitory pathways; however whether these opposing signals are dynamically regulated during healthy behavior is not known. Here, we present compelling neurophysiological evidence from three complimentary experiments in non-human primates, indicating task-specific changes in tonic BG pathway weightings during saccade behavior with different cognitive demands. First, simultaneous local field potential recording in the subthalamic nucleus (STN; BG input) and substantia nigra pars reticulata (SNr; BG output) reveals task-dependent shifts in subthalamo-nigral signals...
October 19, 2017: Nature Communications
https://www.readbyqxmd.com/read/29051394/evolution-on-rugged-adaptive-landscapes
#18
Uri Obolski, Yoav Ram, Lilach Hadany
Adaptive landscapes represent a mapping between genotype and fitness. Rugged adaptive landscapes contain two or more adaptive peaks: allele combinations with higher fitness than any of their neighbors on the genetic space. How would a population evolve on such rugged landscapes? Evolutionary biologists have struggled with this question since it was first introduced in the 1930's by Sewall Wright. Discoveries in the fields of genetics and biochemistry inspired various mathematical models of adaptive landscapes...
October 20, 2017: Reports on Progress in Physics
https://www.readbyqxmd.com/read/29050062/-cerebral-emergency-important-anesthesiological-aspects
#19
Martin Schott, Klaus-Peter Stein, Martin Bauer
The anesthesiological management of cerebral emergency represents a great challenge for action under pressure and under time pressure and requires smooth interprofessional cooperation. The exact knowledge of the pathophysiological and pharmacological relationships is the basis for rapid identification of therapeutic influences and possible disturbing factors. In the acute situation, paCO2 and MAP are the central determinants for the anesthetist to ensure cerebral perfusion and the resulting cerebral oxygenation...
October 2017: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://www.readbyqxmd.com/read/29050058/-ambulant-anesthesia-limits-and-possibilities
#20
Harald Hofer, Frank Vescia
The number of operations carried out on an outpatient basis is increasing in Germany. This trend has been observed for years. The prerequisite is an infrastructure that is in line with guidelines. The competence of the anesthetist must not be restricted to that of a standard specialist anesthetist, but the physician should have experience in ambulatory anesthesia. Well-adjusted comorbidities of the patient are generally not a contraindication for an outpatient procedure. The heavily overweight patient can also be operated on an outpatient basis if he is compliant, comorbidities are well adjusted and intensive postoperative care is ensured...
October 2017: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
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