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Mismatch Negativity

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https://www.readbyqxmd.com/read/28229115/data-on-the-auditory-duration-mismatch-negativity-for-different-sound-pressure-levels-and-visual-perceptual-loads
#1
Stefan Wiens, Malina Szychowska, Rasmus Eklund, Mats E Nilsson
The data presented in this article are related to our research article entitled "Effects of sound pressure level and visual perceptual load on the auditory mismatch negativity" (M. Szychowska, R. Eklund, M.E. Nilsson, S. Wiens, 2016) [1]. The duration MMN was recorded at three sound pressure levels (SPLs) during two levels of visual perceptual load. In an oddball paradigm (standard=75 ms, deviant=30 ms, within-subjects design), participants were presented with tones at 56, 66, or 76 dB SPL (between-subjects design)...
April 2017: Data in Brief
https://www.readbyqxmd.com/read/28227552/research-on-eeg-features-of-attended-unattended-vigilance
#2
Chang Sun, Runge Chen, Miao Tian, Xingwei An, Hongzhi Qi, Minpeng Xu, Xuemin Wang, Dong Ming, Peng Zhou, Chang Sun, Runge Chen, Miao Tian, Xingwei An, Hongzhi Qi, Minpeng Xu, Xuemin Wang, Dong Ming, Peng Zhou, Miao Tian, Minpeng Xu, Hongzhi Qi, Runge Chen, Dong Ming, Chang Sun, Xingwei An, Peng Zhou, Xuemin Wang
Vigilance refers to the brain alertness to objective things, including the concentration of attention and the capability to response emergencies. It is of great importance to study vigilance monitoring to avoid accidents caused by decrease of vigilance. In this study, traditional Mackworth Clock Test (MCT) was modified to induce decline of attended and unattended vigilance. We analyzed EEG features in different levels of attended vigilance and assessed unattended vigilance by amplitude of mismatch negative (MMN) which can be evoked by audio odd ball stimulations...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226815/multi-domain-feature-selection-in-auditory-mismatch-negativity-via-parafac-based-template-matching-approach
#3
Saeed Pouryazdian, Andrew Chang, Dan J Bosnyak, Laurel J Trainor, Soosan Beheshti, Sridhar Krishnan, Saeed Pouryazdian, Andrew Chang, Dan J Bosnyak, Laurel J Trainor, Soosan Beheshti, Sridhar Krishnan, Soosan Beheshti, Dan J Bosnyak, Laurel J Trainor, Sridhar Krishnan, Saeed Pouryazdian, Andrew Chang
MisMatch Negativity (MMN) is a small event-related potential (ERP) that provide an index of sensory learning and perceptual accuracy for the cognitive research. Group-level analysis plays an important role for detecting differences at group or condition level, especially when the signal-to-noise ratio is low. Tensor factorization has provided a framework for group-level analysis of ERPs by exploiting more information of brain responses in more domains simultaneously. A 4-way ERP tensor of time × frequency × channel × subjects/condition is generated and decomposed via PARAFAC...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226659/automatic-and-continuous-assessment-of-erps-for-mismatch-negativity-detection
#4
Narges Armanfard, Majid Komeili, James P Reilly, Richard Mah, John F Connolly, Narges Armanfard, Majid Komeili, James P Reilly, Richard Mah, John F Connolly, John F Connolly, Majid Komeili, Narges Armanfard, James P Reilly, Richard Mah
Accurate and fast detection of event related potential (ERP) components is an unresolved issue in neuroscience and critical health care. Mismatch negativity (MMN) is a component of the ERP to an odd stimulus in a sequence of identical stimuli which has good correlation with coma awakening. All of the previous studies for MMN detection are based on visual inspection of the averaged ERPs (over a long recording time) by a skilled neurophysiologist. However, in practical situations, such an expert may not be available or familiar with all aspects of evoked potential methods...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28221380/spatial-mismatch-non-additive-binding-energies-and-selectivity-in-supramolecular-complexes
#5
REVIEW
Hans-Jörg Schneider
The consequences of spatial mismatch between a receptor and ligand on affinity and selectivity of supramolecular complexes are illustrated with several examples. Conformationally rigid complexes and shorter-range non-covalent forces are characterized by large affinity changes, in contrast to more flexible systems. In the most frequent complexes with several spaciously separated binding sites, the additivity of binding energies and the correlation between affinity and selectivity is often lost by partial mismatch...
February 21, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28218796/brain-activity-from-stimuli-that-are-not-perceived-visual-mismatch-negativity-during-binocular-rivalry-suppression
#6
Bradley N Jack, Andreas Widmann, Robert P O'Shea, Erich Schröger, Urte Roeber
Predictive coding explains visual perception as the result of an interaction between bottom-up sensory input and top-down generative models at each level of the visual hierarchy. Evidence for this comes from the visual mismatch negativity (vMMN): a more negative ERP for rare, unpredictable visual stimuli-deviants, than for frequent, predictable visual stimuli-standards. Here, we show that the vMMN does not require conscious experience. We measured the vMMN from monocular luminance-decrement deviants that were either perceived or not during binocular rivalry dominance or suppression, respectively...
February 20, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28217023/metabolic-bone-disease-in-the-context-of-metastatic-neuroendocrine-tumor-differentiation-from-skeletal-metastasis-the-molecular-pet-ct-imaging-features-and-exploring-the-possible-etiopathologies-including-parathyroid-adenoma-men1-and-paraneoplastic-humoral
#7
Rohit Ranade, Sandip Basu
Three cases of metabolic bone disease in the setting of metastatic neuroendocrine tumor (NET) are illustrated with associated etiopathologies.  One of these cases harbored mixed lesions in the form of vertebral metastasis (biopsy proven) while the other skeletal lesions were caused due to metabolic bone disease related to multiple parathyroid adenomas. While the metastatic lesion was positive on 68Ga-DOTATATE positron emission tomography-computed tomography (PET-CT), the lesions of metabolic bone disease were negative and the 18F-fluoride PET-CT demonstrated the features of metabolic bone scan...
January 2017: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28210747/extent-of-field-change-in-colorectal-cancers-with-braf-mutation
#8
Aaron Poh, Heidi Sian Ying Chang, Kok Yang Tan, Xin Xiu Sam, Avery Khoo, Shoa Nian Choo, Min En Nga, Wei Keat Wan
INTRODUCTION: Sporadic colorectal cancers with BRAF mutations constitute two distinct subgroups of colorectal cancers. Recent studies have linked the presence of the BRAF mutation to a familial inheritance pattern. This was a proof-of-concept study that aimed to examine: (a) the extent of field change in sporadic colorectal cancers with BRAF mutation; and (b) the extent of resection margins required and the pattern of DNA mismatch repair protein loss in these tumours. METHODS: Eight microsatellite instability-high (MSI-H) tumours with positive BRAF mutation from an existing histopathological database were selected for BRAF mutation and mismatch repair protein analysis...
February 17, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28201902/graphene-contacts-to-a-hfse2-sns2-heterostructure
#9
Shanshan Su, Protik Das, Supeng Ge, Roger K Lake
Two-dimensional (2D) heterostructures and all-2D contacts are of high interest for electronic device applications, and the SnS2/HfSe2 bilayer heterostructure with graphene contacts has some unique, advantageous properties. The SnS2/HfSe2 heterostructure is interesting because of the strong intermixing of the two conduction bands and the large work function of the SnS2. The band lineup of the well separated materials indicates a type II heterostructure, but the conduction band minimum of the SnS2/HfSe2 bilayer is a coherent superposition of the orbitals from the two layers with a spectral weight of 60% on the SnS2 and 40% on the HfSe2 for AA stacking...
February 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28197097/when-elderly-outperform-young-adults-integration-in-vision-revealed-by-the-visual-mismatch-negativity
#10
Zsófia Anna Gaál, Flóra Bodnár, István Czigler
We studied the possibility of age-related differences of visual integration at an automatic and at a task-related level. Data of 15 young (21.9 ± 1.8 years) and 15 older (66.6 ± 3.5 years) women were analyzed in our experiment. Automatic processing was investigated in a passive oddball paradigm, and the visual mismatch negativity (vMMN) of event-related brain potentials was measured. Letters and pseudo-letters were presented either as single characters, or the characters were presented successively in two fragments...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28194102/facial-expression-related-vmmn-disentangling-emotional-from-neutral-change-detection
#11
Klara Kovarski, Marianne Latinus, Judith Charpentier, Helen Cléry, Sylvie Roux, Emmanuelle Houy-Durand, Agathe Saby, Frédérique Bonnet-Brilhault, Magali Batty, Marie Gomot
Detection of changes in facial emotional expressions is crucial to communicate and to rapidly and automatically process possible threats in the environment. Recent studies suggest that expression-related visual mismatch negativity (vMMN) reflects automatic processing of emotional changes. In the present study we used a controlled paradigm to investigate the specificity of emotional change-detection. In order to disentangle specific responses to emotional deviants from that of neutral deviants, we presented neutral expression as standard stimulus (p = 0...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28193730/mismatch-repair-incompatibilities-in-diverse-yeast-populations
#12
Duyen T Bui, Anne Friedrich, Najla Al-Sweel, Gianni Liti, Joseph Schacherer, Charles F Aquadro, Eric Alani
An elevated mutation rate can provide cells with a source of mutations to adapt to changing environments. We identified a negative-epistatic interaction involving naturally occurring variants in the MLH1 and PMS1 mismatch repair (MMR) genes of Saccharomyces cerevisiae We hypothesized that this MMR incompatibility, created through mating between divergent S. cerevisiae, yields mutator progeny that can rapidly but transiently adapt to an environmental stress. Here we analyzed the MLH1 and PMS1 genes across 1,010 S...
February 13, 2017: Genetics
https://www.readbyqxmd.com/read/28189096/abnormal-agency-experiences-in-schizophrenia-patients-examining-the-role-of-psychotic-symptoms-and-familial-risk
#13
Merel Prikken, Anouk van der Weiden, Robert A Renes, Martijn G J C Koevoets, Henriette D Heering, René S Kahn, Henk Aarts, Neeltje E M van Haren
Experiencing self-agency over one's own action outcomes is essential for social functioning. Recent research revealed that patients with schizophrenia do not use implicitly available information about their action-outcomes (i.e., prime-based agency inference) to arrive at self-agency experiences. Here, we examined whether this is related to symptoms and/or familial risk to develop the disease. Fifty-four patients, 54 controls, and 19 unaffected (and unrelated) siblings performed an agency inference task, in which experienced agency was measured over action-outcomes that matched or mismatched outcome-primes that were presented before action performance...
November 1, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/28187217/electrophysiological-cognitive-and-clinical-profiles-of-at-risk-mental-state-the-longitudinal-minds-in-transition-mint-study
#14
Rebbekah J Atkinson, W Ross Fulham, Patricia T Michie, Philip B Ward, Juanita Todd, Helen Stain, Robyn Langdon, Renate Thienel, Georgie Paulik, Gavin Cooper, Ulrich Schall
The onset of schizophrenia is typically preceded by a prodromal period lasting several years during which sub-threshold symptoms may be identified retrospectively. Clinical interviews are currently used to identify individuals who have an ultra-high risk (UHR) of developing a psychotic illness with a view to provision of interventions that prevent, delay or reduce severity of future mental health issues. The utility of bio-markers as an adjunct in the identification of UHR individuals is not yet established...
2017: PloS One
https://www.readbyqxmd.com/read/28179957/simplified-detection-of-the-hybridized-dna-using-a-graphene-field-effect-transistor
#15
Arun Kumar Manoharan, Shanmugavel Chinnathambi, Ramasamy Jayavel, Nobutaka Hanagata
Detection of disease-related gene expression by DNA hybridization is a useful diagnostic method. In this study a monolayer graphene field effect transistor (GFET) was fabricated for the detection of a particular single-stranded DNA (target DNA). The probe DNA, which is a single-stranded DNA with a complementary nucleotide sequence, was directly immobilized onto the graphene surface without any linker. The VDirac was shifted to the negative direction in the probe DNA immobilization. A further shift of VDirac in the negative direction was observed when the target DNA was applied to GFET, but no shift was observed upon the application of non-complementary mismatched DNA...
2017: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/28169438/association-between-parental-access-to-paid-sick-leave-and-children-s-access-to-and-use-of-healthcare-services
#16
Abay Asfaw, Maria Colopy
BACKGROUND: We examined the association between parental access to paid sick leave (PPSL) and children's use of preventive care and reduced likelihood of delayed medical care and emergency room (ER) visits. METHODS: We used the child sample of the National Health Interview Survey data (linked to the adult and family samples) from 2011 through 2015 and logistic and negative binomial regression models. RESULTS: Controlling for covariates, the odds of children with PPSL receiving flu vaccination were 12...
February 7, 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/28169421/n1-response-attenuation-and-the-mismatch-negativity-mmn-to-within-and-across-category-phonetic-contrasts
#17
Daniel M R Silva, Danilo B Melges, Rui Rothe-Neves
According to the neural adaptation model of the mismatch negativity (MMN), the sensitivity of this event-related response to both acoustic and categorical information in speech sounds can be accounted for by assuming that (a) the degree of overlapping between neural representations of two sounds depends on both the acoustic difference between them and whether or not they belong to distinct phonetic categories, and (b) a release from stimulus-specific adaptation causes an enhanced N1 obligatory response to infrequent deviant stimuli...
February 7, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28167837/neural-mechanisms-of-mismatch-negativity-dysfunction-in-schizophrenia
#18
M Lee, P Sehatpour, M J Hoptman, P Lakatos, E C Dias, J T Kantrowitz, A M Martinez, D C Javitt
Schizophrenia is associated with cognitive deficits that reflect impaired cortical information processing. Mismatch negativity (MMN) indexes pre-attentive information processing dysfunction at the level of primary auditory cortex. This study investigates mechanisms underlying MMN impairments in schizophrenia using event-related potential, event-related spectral decomposition (ERSP) and resting state functional connectivity (rsfcMRI) approaches. For this study, MMN data to frequency, intensity and duration-deviants were analyzed from 69 schizophrenia patients and 38 healthy controls...
February 7, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28157900/single-camera-full-range-high-resolution-spectral-domain-optical-coherence-tomography
#19
En Bo, Si Chen, Dongyao Cui, Shi Chen, Xiaojun Yu, Yuemei Luo, Linbo Liu
We developed spectral domain optical coherence tomography using a dual-channel spectrometer for complex conjugate artifacts (CCA) suppression. We used a three-line charge coupled device to simultaneously detect two interferometric spectra with 2π/3 phase difference. The complex interferometric signal was reconstructed by trigonometric manipulation of two real interferometric spectra, and then full-range images were obtained by use of inverse Fourier transform. Artifacts at direct current (DC) and the ghost remnant of the CCA are common issues with the previously reported two-spectrometer method because the slight mismatching between two spectral detection channels had strong negative effects on CCA suppression and appeared to be the limiting factor on system performance...
January 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28144832/cognitive-basis-of-individual-differences-in-speech-perception-production-and-representations-the-role-of-domain-general-attentional-switching
#20
Jinghua Ou, Sam-Po Law
This study investigated whether individual differences in cognitive functions, attentional abilities in particular, were associated with individual differences in the quality of phonological representations, resulting in variability in speech perception and production. To do so, we took advantage of a tone merging phenomenon in Cantonese, and identified three groups of typically developed speakers who could differentiate the two rising tones (high and low rising) in both perception and production [+Per+Pro], only in perception [+Per-Pro], or in neither modalities [-Per-Pro]...
January 31, 2017: Attention, Perception & Psychophysics
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