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https://www.readbyqxmd.com/read/28875069/mutation-detection-and-prenatal-diagnosis-of-xlhed-pedigree
#1
Yao Lin, Wei Yin, Zhuan Bian
BACKGROUND: The phenotypic characters of X -linked Hypohidrotic Ectodermal Dysplasia (XLHED) are the dysplasia of epithelial- and mesenchymal-derived organs. Ectodysplasin (EDA) is the causative gene of XLHED. METHODS: The current study reported a large Chinese XLHED pedigree. The genomic DNA of adult and fetus was extracted from peripheral blood and shed chorion cell respectively. The nucleotide variation in EDA gene was screened through direct sequencing the coding sequence...
2017: PeerJ
https://www.readbyqxmd.com/read/28870340/gc-ms-analysis-of-volatile-compounds-of-perilla-frutescens-britton-var-japonica-accessions-morphological-and-seasonal-variability
#2
Bimal Kumar Ghimire, Ji Hye Yoo, Chang Yeon Yu, Ill-Min Chung
OBJECTIVE: To investigate the composition of volatile compounds in the different accessions of Perilla frutescens (P. frutescens) collected from various habitats of China and Japan. METHODS: In the present study, the essential oil from the leaves of P. frutescens cultivars from China and Japan was extracted by hydro-distillation and the chemical composition and concentration of the volatile components present in the oils were determined by gas chromatography-mass spectrometry (GC-MS) analysis...
July 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28869288/exploring-the-mechanism-of-jieduquyuziyin-prescription-on-systemic-lupus-erythematosus-by-gc-ms-based-urine-metabolomics
#3
Jing Wei, Jun Gao, Xinghong Ding
A urine metabolomics method based on gas chromatography mass spectrometry (GC-MS) was developed in order to investigate the metabolites characters of systemic lupus erythematosus (SLE) and therapeutic effects of jieduquyuziyin prescription (JP). The urinary metabolic profiles in urine specimens of the SLE model mice (MRL/lpr) group, prednisone acetate (PA)-treated SLE mice group, JP-treated SLE mice group, and control group (C57BL/6 J) after the administration were analyzed by GC-MS. These metabolic profiles were then processed by multivariate analysis, in particular Mass Profiler Professional (MPP), SIMCA-P and partial least-squares discriminant analysis (PLS-DA)...
September 4, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/28862057/biological-characteristics-of-edgeworthia-tomentosa-thunb-nakai-flowers-and-antimicrobial-properties-of-their-essential-oils
#4
Yanfang Sun, Zhangqi Wang, Boqi Li, Farukh S Sharopov, Pan Wang, Yang Suen, Zongsuo Liang
Edgeworthia tomentosa (Thunb.) Nakai belongs to Thymelaeaceae family, its alabastrum is used as the traditional Chinese medicine 'Buddleja Officinalis Maxim'. The present study was to elucidate the ultrastructure characteristics of the flower, the phytochemical composition of the aroma essential oils (EOs) and the relevant antimicrobial properties. There were exclusive characters of calyx, ovule, anther and pollen grain of the flowers under scanning electron microscopy. A total of 40 phytochemical components representing 98% of the EOs were successfully identified: monoterpenes and sesquiterpenes were the dominant terpenoids according to Kovats retention index and MS database...
September 1, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28855651/a-novel-sex-linked-mutant-affecting-tail-formation-in-hongshan-chicken
#5
Qiong Wang, Jinsong Pi, Ailuan Pan, Jie Shen, Lujiang Qu
The Hongshan chicken is a Chinese indigenous breed that has two distinctly different tail types. Some chickens have stunted tails as compared to the normal phenotype, and they are termed rumpless. Rumplessness in other chicken breeds was caused by a reduction in the number of coccygeal vertebrae. However, X-ray examination showed that rumpless Hongshan chickens possess the normal number of coccygeal vertebrae. Our analyses of the main tail feathers and tissue sections led us to speculate that their stunted tail appearance may be the result of abnormal feather development...
August 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28840688/-molecular-authentication-of-jinyinhua-formula-granule-by-using-allele-specific-pcr
#6
Chao Jiang, Li-Chan Tu, Yuan Yuan, Lu-Qi Huang, Wei Gao, Yan Jin
Traditional authentication method is hard to identify herb's authenticity of traditional Chinese medicine(TCM) formula granules because they have lost all their morphological characteristics. In this study, a new allele-specific PCR method was established for identifying the authentication of Jinyinhua formula granule (made from Lonicerae Japonicae Flos) based on an SNP site in trnL-trnF fragment. Genomic DNA was successfully extracted from Lonicerae Japonicae Flos and its formula granules by using an improved spin column method and then PCR was performed with the designed primer...
July 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28805490/low-employment-and-low-willingness-of-being-reemployed-in-chinese-working-age-maintained-hemodialysis-patients
#7
Bihong Huang, Bihong Lai, Ling Xu, Ying Wang, Yanpei Cao, Ping Yan, Jing Chen
AIM: Returning to society plays an important role in improving the quality of life in maintenance hemodialysis (MHD) patients, and retention of employment is one of the core enablers. The study is to assess the employment status and to determine the variables for unemployment in Chinese MHD patients. METHODS: Prevalent MHD patients from four dialysis centers in Shanghai China were enrolled. We assessed patients' employment status, current social functioning, hemodialysis modality, annual income and general health condition...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/28798392/new-findings-in-a-400-million-year-old-devonian-placoderm-shed-light-on-jaw-structure-and-function-in-basal-gnathostomes
#8
Yuzhi Hu, Jing Lu, Gavin C Young
Arthodire placoderms have been proposed as the sister group of Chinese 'maxillate' placoderms plus all the more crownward gnathostomes. These basal groups provide key information for understanding the early evolution of jaws. Here, we test previous assumptions about placoderm jaw structure and function by using high-resolution computed tomography, digital dissection, and enlarged 3D printouts on a unique articulated 400 million-year-old buchanosteid arthrodire. The upper jaw has a double ethmoid and a palatobasal connection, but no otic connection; the dermal bone attachment for the quadrate is different to other placoderms...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28771010/systems-pharmacology-dissection-of-multiscale-mechanisms-of-action-for-herbal-medicines-in-treating-rheumatoid-arthritis
#9
Jinghui Wang, Yan Li, Yinfeng Yang, Jian Du, Miaoqing Zhao, Feng Lin, Shuwei Zhang, Bin Wang
As a chronic inflammatory and angiogenic disease with increased morbidity and mortality, rheumatoid arthritis (RA) is characterized by the proliferation of synovial tissue and the accumulation of excessive mononuclear infiltration, which always results in the joint deformity, disability, and eventually the destruction of the bone and cartilage. Traditional Chinese Medicine (TCM), with rich history of proper effectiveness in treating the inflammatory joint disease containing RA, has long combated such illness from, actually, an integrative and holistic point of view...
August 22, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28770465/tracking-the-eye-movement-of-four-years-old-children-learning-chinese-words
#10
Dan Lin, Guangyao Chen, Yingyi Liu, Jiaxin Liu, Jue Pan, Lei Mo
Storybook reading is the major source of literacy exposure for beginning readers. The present study tracked 4-year-old Chinese children's eye movements while they were reading simulated storybook pages. Their eye-movement patterns were examined in relation to their word learning gains. The same reading list, consisting of 20 two-character Chinese words, was used in the pretest, 5-min eye-tracking learning session, and posttest. Additionally, visual spatial skill and phonological awareness were assessed in the pretest as cognitive controls...
August 2, 2017: Journal of Psycholinguistic Research
https://www.readbyqxmd.com/read/28767364/learning-spatial-semantic-context-with-fully-convolutional-recurrent-network-for-online-handwritten-chinese-text-recognition
#11
Zecheng Xie, Zenghui Sun, Lianwen Jin, Hao Ni, Terry Lyons
Online handwritten Chinese text recognition (OHCTR) is a challenging problem as it involves a large-scale character set, ambiguous segmentation, and variable-length input sequences. In this paper, we exploit the outstanding capability of path signature to translate online pen-tip trajectories into informative signature feature maps, successfully capturing the analytic and geometric properties of pen strokes with strong local invariance and robustness. A multi-spatial-context fully convolutional recurrent network (MC-FCRN) is proposed to exploit the multiple spatial contexts from the signature feature maps and generate a prediction sequence while completely avoiding the difficult segmentation problem...
July 28, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28746187/research-of-cerebral-activation-in-uygur-speaking-and-chinese-speaking-participants-during-verb-generation-task-with-functional-magnetic-resonance-imaging
#12
COMPARATIVE STUDY
Yanling Xi, Ling Liu, Grace Hao, Zulipinuer Abudusadike, Chunhui Jiang, Junran Zhang, Baolan Wang
The aims are to investigate and compare the activated cerebral regions of Uygur-speaking and Chinese-speaking participants during verb generation task.A total of 31 cases of Uygur and 28 cases of Han healthy volunteers were enrolled. They were requested to take verb generation tasks. Blood oxygenation level-dependent functional magnetic resonance imaging (BOLD-fMRI) was performed. The fMRI images were collected and activated brain regions were analyzed.In Chinese-speaking participants, the main activated cerebral regions were as follows: the left caudate nucleus, the left occipital gyrus, the left fusiform gyrus, bilateral supplementary motor area (BA8/ 6), the left BA32, left precuneus, the left superior parietal lobule, the left inferior parietal lobule (BA7), the left angular gyrus, the right side of the central gyrus (BA9), the left inferior frontal gyrus triangular section, the right pars opercularis gyri frontalis inferiorista, and bilateral cerebellum...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28744953/a-three-year-longitudinal-study-of-reading-and-spelling-difficulty-in-chinese-developmental-dyslexia-the-matter-of-morphological-awareness
#13
Xiuhong Tong, Catherine McBride, Jason Chor Ming Lo, Hua Shu
In the present study, we used a three-time point longitudinal design to investigate the associations of morphological awareness to word reading and spelling in a small group of those with and without dyslexia taken from a larger sample of 164 Hong Kong Chinese children who remained in a longitudinal study across ages 6, 7 and 8. Among those 164 children, 15 had been diagnosed as having dyslexia by professional psychologists, and 15 other children manifested average reading ability and had been randomly selected from the sample for comparison...
July 25, 2017: Dyslexia: the Journal of the British Dyslexia Association
https://www.readbyqxmd.com/read/28719957/four-human-cases-of-diphyllobothrium-nihonkaiense-eucestoda-diphyllobothriidae-in-china-with-a-brief-review-of-chinese-cases
#14
Yu-Chun Cai, Shao-Hong Chen, Hiroshi Yamasaki, Jia-Xu Chen, Yan Lu, Yong-Nian Zhang, Hao Li, Lin Ai, Hai-Ning Chen
We described 4 human infection cases of zoonotic fish-tapeworm, Diphyllobothrium nihonkaiense, identified with morphological and molecular characters and briefly reviewed Chinese cases in consideration of it as an emerging parasitic disease in China. The scolex and mature and gravid proglottids of some cases were seen, a rosette-shaped uterus was observed in the middle of the mature and gravid proglottids, and the diphyllobothriid eggs were yellowish-brown in color and displayed a small knob or abopercular protuberance on the opposite end of a lid-like opening...
June 2017: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28718970/activation-of-semantic-information-at-the-sublexical-level-during-handwriting-production-evidence-from-inhibition-effects-of-chinese-semantic-radicals-in-the-picture-word-interference-paradigm
#15
Xuqian Chen, Yuanlan Liao, Xianzhe Chen
Using a non-alphabetic language (e.g., Chinese), the present study tested a novel view that semantic information at the sublexical level should be activated during handwriting production. Over 80% of Chinese characters are phonograms, in which semantic radicals represent category information (e.g., 'chair,' 'peach,' 'orange' are related to plants) while phonetic radicals represent phonetic information (e.g., 'wolf,' 'brightness,' 'male,' are all pronounced /lang/). Under different semantic category conditions at the lexical level (semantically related in Experiment 1; semantically unrelated in Experiment 2), the orthographic relatedness and semantic relatedness of semantic radicals in the picture name and its distractor were manipulated under different SOAs (i...
August 2017: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/28710600/the-influence-of-orthographic-experience-on-the-development-of-phonological-preparation-in-spoken-word-production
#16
Chuchu Li, Min Wang
Three sets of experiments using the picture naming tasks with the form preparation paradigm investigated the influence of orthographic experience on the development of phonological preparation unit in spoken word production in native Mandarin-speaking children. Participants included kindergarten children who have not received formal literacy instruction, Grade 1 children who are comparatively more exposed to the alphabetic pinyin system and have very limited Chinese character knowledge, Grades 2 and 4 children who have better character knowledge and more exposure to characters, and skilled adult readers who have the most advanced character knowledge and most exposure to characters...
August 2017: Memory & Cognition
https://www.readbyqxmd.com/read/28693370/toward-a-graded-psycholexical-space-mapping-model-sublexical-and-lexical-representations-in-chinese-character-reading-development
#17
Xiuli Tong, Catherine McBride
Following a review of contemporary models of word-level processing for reading and their limitations, we propose a new hypothetical model of Chinese character reading, namely, the graded lexical space mapping model that characterizes how sublexical radicals and lexical information are involved in Chinese character reading development. The underlying assumption of this model is that Chinese character recognition is a process of competitive mappings of phonology, semantics, and orthography in both lexical and sublexical systems, operating as functions of statistical properties of print input based on the individual's specific level of reading...
July 1, 2017: Journal of Learning Disabilities
https://www.readbyqxmd.com/read/28691535/promoting-free-flow-in-the-networks-reimagining-the-body-in-early-modern-suzhou
#18
Volker Scheid
The history of Chinese medicine is still widely imagined in terms dictated by the discourse of modernity, that is as 'traditional' and 'Chinese.' And yet, so as to be intelligible to us moderns, it must simultaneously be framed through categories that make it comparable somehow to the 'West' and the 'modern' from which it is said to be essentially different. This is accomplished, for instance, by viewing Chinese medicine as fundamentally shaped by cosmological thinking, as focusing on process rather than matter, and as forever hampered by attachments to the past even when it tries to innovate...
June 1, 2017: History of Science; An Annual Review of Literature, Research and Teaching
https://www.readbyqxmd.com/read/28686503/characterization-of-carbapenem-resistant-escherichia-coli-isolates-through-the-whole-genome-sequencing-analysis
#19
Yanping Luo, Rong Luo, Hong Ding, Xiu Ren, Haipeng Luo, Ying Zhang, Liyan Ye, Shenghui Cui
Limited studies have characterized multiple carbapenem-resistant Escherichia coli isolates and compared their genetic characteristics through whole-genome sequencing (WGS) because of the scarcity of these isolates. In this study, we determined the prevalence of carbapenem resistance in 2,993 E. coli isolates collected from three Chinese hospitals. The carbapenem-resistant isolates were further characterized by WGS, and the molecular epidemiological characters and resistance mechanisms were explored through the publicly available platforms from the Center for Genomic Epidemiology...
July 7, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28673532/drug-use-among-asian-americans-differentiating-use-by-acculturation-status-and-gender
#20
Clifford S Bersamira, Yu-An Lin, Keunhye Park, Jeanne C Marsh
This study examined past-year drug use among Asian Americans with respect to ethnic subgroup, acculturation, and gender differences. Survey data were collected during the National Latino and Asian American Survey, a national epidemiological household survey of behavioral health prevalence and service utilization rates. The analytical sample consisted of 505 Filipino, 598 Chinese, 518 Vietnamese, and 466 other Asian respondents. Results indicated that among ethnic subgroups, Filipinos had the highest rates of drug use...
August 2017: Journal of Substance Abuse Treatment
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