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https://www.readbyqxmd.com/read/28343123/estimation-of-red-light-running-frequency-using-high-resolution-traffic-and-signal-data
#1
Peng Chen, Guizhen Yu, Xinkai Wu, Yilong Ren, Yueguang Li
Red-light-running (RLR) emerges as a major cause that may lead to intersection-related crashes and endanger intersection safety. To reduce RLR violations, it's critical to identify the influential factors associated with RLR and estimate RLR frequency. Without resorting to video camera recordings, this study investigates this important issue by utilizing high-resolution traffic and signal event data collected from loop detectors at five intersections on Trunk Highway 55, Minneapolis, MN. First, a simple method is proposed to identify RLR by fully utilizing the information obtained from stop bar detectors, downstream entrance detectors and advance detectors...
March 23, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28342596/the-practical-application-of-scintillation-dosimetry-in-small-field-photon-beam-radiotherapy
#2
Elisa Burke, Daniela Poppinga, Andreas A Schönfeld, Dietrich Harder, Björn Poppe, Hui Khee Looe
Plastic scintillation detectors are a new instrument of stereotactic photon-beam dosimetry. The clinical application of the plastic scintillation detector Exradin W1 at the Siemens Artiste and Elekta Synergy accelerators is a matter of current interest. In order to reduce the measurement uncertainty, precautions have to be taken with regard to the geometrical arrangement of the scintillator, the light-guide fiber and the photodiode in the radiation field. To determine the "Cerenkov light ratio" CLR with a type A uncertainty below 1%, the Cerenkov calibration procedure for small-field measurements based on the two-channel spectral method was used...
March 22, 2017: Zeitschrift Für Medizinische Physik
https://www.readbyqxmd.com/read/28342383/own-attractiveness-and-perceived-relationship-quality-shape-sensitivity-in-women-s-memory-for-other-men-on-the-attractiveness-dimension
#3
Christopher D Watkins, Mike J Nicholls, Carlota Batres, Dengke Xiao, Sean Talamas, David I Perrett
Although recent work suggests that opposite-sex facial attractiveness is less salient in memory when individuals are in a committed romantic relationship, romantic relationship quality can vary over time. In light of this, we tested whether activating concerns about romantic relationship quality strengthens memory for attractive faces. Partnered women were exposed briefly to faces manipulated in shape cues to attractiveness before either being asked to think about a moment of emotional closeness or distance in their current relationship...
March 22, 2017: Cognition
https://www.readbyqxmd.com/read/28342354/integrated-ion-imprinted-polymers-paper-composites-for-selective-and-sensitive-detection-of-cd-ii-ions
#4
Kai Huang, Ying Chen, Feng Zhou, Xiaoya Zhao, Jiafa Liu, Surong Mei, Yikai Zhou, Tao Jing
Paper-based sensor is a new alternative technology to develop a portable, low-cost, and rapid analysis system in environmental chemistry. In this study, ion imprinted polymers (IIPs) using cadmium ions as the template were directly grafted on the surface of low-cost print paper based on the reversible addition-fragmentation chain transfer polymerization. It can be applied as a recognition element to selectively capture the target ions in the complex samples. The maximum adsorption capacity of IIPs composites was 155...
March 18, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28340328/the-role-of-auxin-response-factors-in-the-development-and-differential-growth-of-inflorescence-stems
#5
Nicholas S Carey, Naden T Krogan
Plants react to environmental cues by altering their growth and development, which can include organ tropic responses. These differential growth responses are triggered by the hormone auxin, and AUXIN RESPONSE FACTORs (ARFs) have been implicated in numerous organ tropisms in Arabidopsis thaliana. Surprisingly, despite being critical for light capture and overall plant morphology, inflorescence stem tropic responses remain relatively understudied, with presumed direct links to ARF function yet to be established...
March 24, 2017: Plant Signaling & Behavior
https://www.readbyqxmd.com/read/28340319/apigenin-reduces-nf-%C3%AE%C2%BAb-and-subsequent-cytokine-production-as-protective-effect-in-a-rodent-animal-model-of-lung-ischemia-reperfusion-injury
#6
Ioannis Bougioukas, Vassilios Didilis, Alexander Emmert, Ahmad F Jebran, Regina Waldmann-Beushausen, Tomislav Stojanovic, Friedrich A Schoendube, Bernhard C Danner
PURPOSE: Lung ischemia-reperfusion injury (LIRI) can complicate lung transplantation or cardiac surgery with cardiopulmonary bypass, increasing morbidity and mortality. In LIRI, pro-inflammatory cytokines are activated, reactive oxygen species are generated and nuclear factor-κB (NF-κB) is up-regulated, altering lung mechanics. We tested the effect of the flavonoid apigenin on a rodent model of LIRI. METHODS: Thirty-seven Wistar rats were subjected to LIRI with or without a single or double dose of apigenin...
March 24, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28339978/ozone-sensitive-arabidopsis-mutants-with-deficiencies-in-photorespiratory-enzymes
#7
Shoko Saji, Srinivas Bathula, Akihiro Kubo, Masanori Tamaoki, Mitsuko Aono, Tomoharu Sano, Kazuo Tobe, Stefan Timm, Hermann Bauwe, Nobuyoshi Nakajima, Hikaru Saji
An ozone-sensitive mutant was isolated from T-DNA-tagged lines of Arabidopsis thaliana. The T-DNA was inserted at a locus on chromosome 3, where two genes encoding glycolate oxidases, GOX1 and GOX2, peroxisomal enzymes involved in photorespiration, reside contiguously. The amounts of the mutant's foliar transcripts for these genes were reduced, and glycolate oxidase activity was approximately 60% of that of the wild-type plants. No difference in growth and appearance was observed between the mutant and the wild-type plants under normal conditions with ambient air under a light intensity of 100 µmol photons m-2 s-1...
February 21, 2017: Plant & Cell Physiology
https://www.readbyqxmd.com/read/28339909/il-17-and-cd40-ligand-synergistically-stimulate-the-chronicity-of-diabetic-nephropathy
#8
Huey-Liang Kuo, Chiu-Ching Huang, Tze-Yi Lin, Ching-Yuang Lin
Background.: Early stages of diabetic nephropathy (DN) are characterized by an influx of inflammatory cells. Interactions between infiltrating T cells and podocytes may play an important role in the ongoing inflammatory response and remodelling. The aim of this study was to explore the role of IL-17 and CD40 ligand (CD40L) in DN. Methods.: The study design involved a case series. Kidney biopsy samples of 69 patients with type 2 diabetes were assessed for the presence of CD4 +  IL-17 +  T cells...
March 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28339779/effect-of-the-combination-of-white-and-red-led-lighting-during-incubation-on-layer-broiler-and-pekin-duck-hatchability
#9
G S Archer, D Jeffrey, Z Tucker
Previous research has shown that providing light during incubation can have positive effects on hatchability and chick quality; however, white light alone has been observed to improve these factors only in pigmented broiler eggs and non-pigmented white layer eggs. Monochromatic red light has been shown to improve hatchability in layer eggs. Therefore the objective of this study was to utilize one light fixture that emitted both white and monochromatic red light to determine if this one light source could improve hatchability in both types of chicken eggs and pigmented Pekin duck egg...
February 23, 2017: Poultry Science
https://www.readbyqxmd.com/read/28339753/in-ovo-monochromatic-green-light-photostimulation-enhances-embryonic-somatotropic-axis-activity
#10
L Dishon, N Avital-Cohen, D Malamud, R Heiblum, S Druyan, T E Porter, M Gumulka, I Rozenboim
Previous studies demonstrated that in ovo photostimulation with monochromatic green light increases body weight and accelerates muscle development in broilers. The mechanism in which in ovo photostimulation accelerates growth and muscle development is not clearly understood. The objective of the current study was to define development of the somatotropic axis in the broiler embryo associated with in ovo green light photostimulation. Two-hundred-forty fertile broiler eggs were divided into 2 groups. The first group was incubated under intermittent monochromatic green light using light-emitting diode (LED) lamps with an intensity of 0...
February 23, 2017: Poultry Science
https://www.readbyqxmd.com/read/28339587/incisor-inclination-and-perceived-tooth-colour-changes
#11
Philip Ciucchi, Stavros Kiliaridis
Introduction: Social attractiveness is influenced by a variety of different smile-related factors. We evaluated whether the degree of upper central incisor proclination can result in tooth colour change. Methods: Forty young adult subjects (20-25 years) in good health with a complete sound dentition were selected. The subjects were seated in standardized light conditions with an above-directed light source. Their natural head position was stated as 0 degrees. To mimic the range of possible anterior torque movements they were asked to tilt their heads upward +15 degrees (upward tilting) and downward -15 degrees (downward tilting)...
January 25, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28339048/agr2-ameliorates-tumor-necrosis-factor-%C3%AE-induced-epithelial-barrier-dysfunction-via-suppression-of-nf-%C3%AE%C2%BAb-p65-mediated-mlck-p-mlc-pathway-activation
#12
Xiaolin Ye, Mei Sun
Intestinal epithelial barrier dysfunction plays a critical role in the pathogenesis of inflammatory bowel disease (IBD). Anterior gradient protein 2 homologue (AGR2) assists in maintaining intestinal homeostasis in dextran sulphate sodium-induced mouse ileocolitis; however, it is unclear whether it modulates intestinal barrier function. Our study aimed to investigate the protective role of AGR2 in tumor necrosis factor (TNF)-α-induced intestinal epithelial barrier injury. Caco-2 cell monolayers were pre-transfected with an AGR2 plasmid and then exposed to TNF-α...
March 21, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28338919/genetic-overlap-between-schizophrenia-and-developmental-psychopathology-longitudinal-and-multivariate-polygenic-risk-prediction-of-common-psychiatric-traits-during-development
#13
Michel G Nivard, Suzanne H Gage, Jouke J Hottenga, Catharina E M van Beijsterveldt, Abdel Abdellaoui, Meike Bartels, Bart M L Baselmans, Lannie Ligthart, Beate St Pourcain, Dorret I Boomsma, Marcus R Munafò, Christel M Middeldorp
BACKGROUND: Several nonpsychotic psychiatric disorders in childhood and adolescence can precede the onset of schizophrenia, but the etiology of this relationship remains unclear. We investigated to what extent the association between schizophrenia and psychiatric disorders in childhood is explained by correlated genetic risk factors. METHODS: Polygenic risk scores (PRS), reflecting an individual's genetic risk for schizophrenia, were constructed for 2588 children from the Netherlands Twin Register (NTR) and 6127 from the Avon Longitudinal Study of Parents And Children (ALSPAC)...
March 11, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28338906/vertical-leaf-mass-per-area-gradient-of-mature-sugar-maple-reflects-both-height-driven-increases-in-vascular-tissue-and-light-driven-increases-in-palisade-layer-thickness
#14
Adam P Coble, Molly A Cavaleri
A key trait used in canopy and ecosystem function modeling, leaf mass per area (LMA), is influenced by changes in both leaf thickness and leaf density (LMA = Thickness × Density). In tall trees, LMA is understood to increase with height through two primary mechanisms: (i) increasing palisade layer thickness (and thus leaf thickness) in response to light and/or (ii) reduced cell expansion and intercellular air space in response to hydrostatic constraints, leading to increased leaf density. Our objective was to investigate within-canopy gradients in leaf anatomical traits in order to understand environmental factors that influence leaf morphology in a sugar maple (Acer saccharum Marshall) forest canopy...
March 3, 2017: Tree Physiology
https://www.readbyqxmd.com/read/28338803/vertical-and-seasonal-variations-in-temperature-responses-of-leaf-respiration-in-a-chamaecyparis-obtusa-canopy
#15
Masatake G Araki, Koichiro Gyokusen, Takuya Kajimoto
Leaf respiration (R) is a major component of carbon balance in forest ecosystems. Clarifying the variability of leaf R within a canopy is essential for predicting the impact of global warming on forest productivity and the potential future function of the forest ecosystem as a carbon sink. We examined vertical and seasonal variations in short-term temperature responses of leaf R as well as environmental factors (light and mean air temperature) and physiological factors [leaf nitrogen (N), leaf mass per area (LMA), and shoot growth] in the canopy of a 10-year-old stand of hinoki cypress [Chamaecyparis obtusa (Sieb...
February 23, 2017: Tree Physiology
https://www.readbyqxmd.com/read/28338794/genome-wide-association-study-unravels-the-genetic-control-of-the-apple-volatilome-and-its-interplay-with-fruit-texture
#16
Brian Farneti, Mario Di Guardo, Iuliia Khomenko, Luca Cappellin, Franco Biasioli, Riccardo Velasco, Fabrizio Costa
Fruit quality represents a fundamental factor guiding consumers' preferences. Among apple quality traits, volatile organic compounds and texture features play a major role. Proton Transfer Reaction-Time of Flight-Mass Spectrometry (PTR-ToF-MS), coupled with an artificial chewing device, was used to profile the entire apple volatilome of 162 apple accessions, while the fruit texture was dissected with a TAXT-AED texture analyzer. The array of volatile compounds was classed into seven major groups and used in a genome-wide association analysis carried out with 9142 single nucleotide polymorphisms (SNPs)...
February 24, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28338619/role-and-function-of-a2a-and-a%C3%A2-adenosine-receptors-in-patients-with-ankylosing-spondylitis-psoriatic-arthritis-and-rheumatoid-arthritis
#17
Annalisa Ravani, Fabrizio Vincenzi, Alessandra Bortoluzzi, Melissa Padovan, Silvia Pasquini, Stefania Gessi, Stefania Merighi, Pier Andrea Borea, Marcello Govoni, Katia Varani
Rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) are chronic inflammatory rheumatic diseases that affect joints, causing debilitating pain and disability. Adenosine receptors (ARs) play a key role in the mechanism of inflammation, and the activation of A2A and A₃AR subtypes is often associated with a reduction of the inflammatory status. The aim of this study was to investigate the involvement of ARs in patients suffering from early-RA (ERA), RA, AS and PsA. Messenger RNA (mRNA) analysis and saturation binding experiments indicated an upregulation of A2A and A₃ARs in lymphocytes obtained from patients when compared with healthy subjects...
March 24, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28337980/light-sensing-via-hydrogen-peroxide-and-a-peroxiredoxin
#18
Kristofer Bodvard, Ken Peeters, Friederike Roger, Natalie Romanov, Aeid Igbaria, Niek Welkenhuysen, Gaël Palais, Wolfgang Reiter, Michel B Toledano, Mikael Käll, Mikael Molin
Yeast lacks dedicated photoreceptors; however, blue light still causes pronounced oscillations of the transcription factor Msn2 into and out of the nucleus. Here we show that this poorly understood phenomenon is initiated by a peroxisomal oxidase, which converts light into a hydrogen peroxide (H2O2) signal that is sensed by the peroxiredoxin Tsa1 and transduced to thioredoxin, to counteract PKA-dependent Msn2 phosphorylation. Upon H2O2, the nuclear retention of PKA catalytic subunits, which contributes to delayed Msn2 nuclear concentration, is antagonized in a Tsa1-dependent manner...
March 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/28337850/high-throughput-screening-of-vascular-endothelium-destructive-or-protective-microenvironments-cooperative-actions-of-extracellular-matrix-composition-stiffness-and-structure
#19
Yonghui Ding, Michael Floren, Wei Tan
Pathological modification of the subendothelial extracellular matrix (ECM) has closely been associated with endothelial activation and subsequent cardiovascular disease progression. To understand regulatory mechanisms of these matrix modifications, the majority of previous efforts have focused on the modulation of either chemical composition or matrix stiffness on 2D smooth surfaces without simultaneously probing their cooperative effects on endothelium function on in vivo like 3D fibrous matrices. To this end, a high-throughput, combinatorial microarray platform on 2D and 3D hydrogel settings to resemble the compositions, stiffness, and structure of healthy and diseased subendothelial ECM has been established, and further their respective and combined effects on endothelial attachment, proliferation, inflammation, and junctional integrity have been investigated...
March 24, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28337631/upregulation-of-mineralocorticoid-receptor-in-the-hypothalamus-associated-with-a-high-anxiety-like-level-in-apolipoprotein-e4-transgenic-mice
#20
Fan-Tao Meng, Jun Zhao, Hui Fang, Li-Feng Zhang, Hui-Mei Wu, Ya-Jing Liu
Anxiety symptoms occur in a large portion of Alzheimer's disease (AD) patients. ApolipoproteinE-4 (ApoE ε4 allele), a risk factor for AD, has been recognized as an important contributor to psychiatric disorders. In the present study, we aimed to investigate the corticosterone level in relation to anxiety-like behavior changes in transgenic male mice with different glial fibrillary acidic protein (GFAP)-ApoE isoforms. GFAP-ApoE4 transgenic mice aged 3 months showed higher anxiety-like behavior in open field, light-dark box and elevated plus maze tasks compared with that of age-matched GFAP-ApoE3 mice...
March 24, 2017: Behavior Genetics
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