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https://www.readbyqxmd.com/read/28638966/measuring-everyday-functional-competence-using-the-rasch-assessment-of-everyday-activity-limitations-real-item-bank
#1
Martijn A H Oude Voshaar, Peter M Ten Klooster, Harald E Vonkeman, Mart A F J van de Laar
OBJECTIVE: Traditional patient-reported physical function instruments often poorly differentiate patients with mild-to-moderate disability. We describe the development and psychometric evaluation of a generic item bank for measuring everyday activity limitations in outpatient populations. STUDY DESIGN AND SETTING: Seventy-two items generated from patient interviews and mapped to the International Classification of Functioning, Disability and Health (ICF) domestic life chapter were administered to 1128 adults representative of the Dutch population...
June 21, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28638852/olfactory-dysfunction-in-patients-with-primary-progressive-ms
#2
Felix A Schmidt, Matthew B Maas, Rohat Geran, Charlotte Schmidt, Hagen Kunte, Klemens Ruprecht, Friedemann Paul, Önder Göktas, Lutz Harms
OBJECTIVE: We tested the hypothesis that olfactory function is more impaired in patients with primary progressive MS (PPMS) than that in relapsing-remitting MS (RRMS). METHODS: Standardized olfactory testing was performed in 32 patients with PPMS, 32 patients with RRMS, and 32 healthy controls (HCs). Patients with olfactory dysfunction due to an alternative primary etiology were excluded. The validated olfactory testing method yielded individual scores for olfactory threshold, odor discrimination, and odor identification, along with a composite Threshold Discrimination Identification (TDI) score...
July 2017: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/28638473/rapid-fluorescence-imaging-of-spinal-cord-following-epidural-administration-of-a-nerve-highlighting-fluorophore
#3
Wanguo Liu, Rui Gu, Qingsan Zhu, Chunsheng Xiao, Lanfeng Huang, Xinming Zhuang, Jingzhe Zhang, Lidi Liu, Ben Ma, Huailin Yang, Jianchao Ma, Zhipeng Hu, Chenglin Tang, Shuhua Zhao, Xuesi Chen
Iatrogenic spinal cord injury (SCI) is the most devastating complication of spine surgery, which usually results in permanent and serious disabilities of patients. Improvement of the visualization and discrimination of the spinal cord is critical for accuracy and safety during surgery; however, to date, there is no suitable technology to fulfill this clinical need. Here, we first show an efficient and rapid fluorescence imaging of the spinal cord in rabbit by epidural administration of a nerve-highlighting fluorophore, i...
2017: Theranostics
https://www.readbyqxmd.com/read/28637600/distinguishing-between-nociceptive-and-neuropathic-components-in-chronic-low-back-pain-using-behavioural-evaluation-and-sensory-examination
#4
N Spahr, D Hodkinson, K Jolly, S Williams, M Howard, M Thacker
BACKGROUND: Diagnosis of chronic low back pain (CLBP) is traditionally predicated on identifying underlying pathological or anatomical causes, with treatment outcomes modest at best. Alternately, it is suggested that identification of underlying pain mechanisms with treatments targeted towards specific pain phenotypes may yield more success. Differentiation between nociceptive and neuropathic components of CLBP is problematic; evidence suggests that clinicians fail to identify a significant neuropathic component in many CLBP patients...
February 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28630816/the-effects-of-an-auditory-matching-ipad-app-on-three-preschoolers-echoic-and-listener-responses
#5
Lin Du, Jeanne Speckman, Megan Medina, Michelle Cole-Hatchard
We investigated the effects of an auditory match-to-sample protocol on three preschoolers' accurate echoics to 100 English words and advanced listener responses. The protocol was presented by using an iPad app Sounds the same: an app to target listening and speaking clearly. We used a combination of a multiple probe design (for echoic responses) and a delayed multiple probe design (for advanced listener literacy responses) with a time-lagged baseline across participants to test the effectiveness of the protocol...
June 2017: Behavior Analysis in Practice
https://www.readbyqxmd.com/read/28629613/out-of-the-institution-into-the-classroom-legal-challenges-to-the-use-of-restraint-and-seclusion-in-school-settings-in-the-united-states
#6
Lycette Nelson
The issue of restraint and seclusion of children with mental and developmental disabilities in schools has gained greater attention in the United States in recent years as more children with disabilities are attending mainstream schools. This article looks at how cases brought on behalf of children who have been subjected to such treatment fit or fail to fit within a well-developed jurisprudence that provides constitutional protections for the rights of people with mental disabilities to be free from discrimination and from cruel and unusual punishment...
June 16, 2017: International Journal of Law and Psychiatry
https://www.readbyqxmd.com/read/28617780/-the-burden-of-disability-in-cameroon
#7
Calogero Foti, Caterina Albensi, Laura Giordani, Yannick Azeufack Ngueko, Martin Sanou Sobze, Vittorio Colizzi
AIM: Rehabilitation services for disabled persons are lacking in countries with limited economic resources. Reliable and objective data are needed to plan for their implementation and to determine the burden of disability in these countries. METHODS: A descriptive cross-sectional study conducted in June 2013 among people living in Dschang Health District, in the West region of Cameroon, to collect information about socio-demographic aspects of physically disabled subjects and health determinants of disabilities...
March 2017: Igiene e Sanità Pubblica
https://www.readbyqxmd.com/read/28608733/differential-profiles-of-four-groups-of-children-referred-to-an-autism-diagnostic-service-in-belgium-autism-specific-hallmarks
#8
Sophie Carlier, Nastasia Kurzeja, Lesley Ducenne, Nathalie Pauwen, Christophe Leys, Véronique Delvenne
OBJECTIVE: This article aims at exploring distinctive hallmarks of autistic disorders compared to other groups presenting mimicking and/or overlapping conditions. METHOD: The exploratory study involved 196 children with autism, intellectual disability, language impairment and psycho-affective disorders previously referred to an autism diagnostic service. The autism discriminative tool (ADT), a behavioural checklist, was used to compile and analyse the children's profiles based on the clinical information gathered during diagnostic assessments...
January 1, 2017: Journal of Intellectual Disabilities: JOID
https://www.readbyqxmd.com/read/28603464/reliability-and-validity-of-the-computerized-dynamic-posturography-sensory-organization-test-in-people-with-multiple-sclerosis
#9
Jeffrey R Hebert, Mark M Manago
BACKGROUND: People with multiple sclerosis (MS) frequently have impaired postural control (balance). Psychometric properties of clinical tests of balance for individuals with MS, including the computerized dynamic posturography sensory organization test (CDP-SOT), are poorly understood. This study aimed to determine the reliability and discriminant validity of the CDP-SOT in people with MS. METHODS: The CDP-SOT was performed on 30 participants with MS. A 2-week-interval, repeated-measures (sessions 1 and 2) design was implemented to investigate test-retest reliability of the CDP-SOT and the ability of the CDP-SOT to discriminate between participants with lower versus higher disability...
May 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28595796/the-metal-and-metalloprotein-profile-of-human-plasma-as-biomarkers-for-stroke-diagnosis
#10
Keaton S Nahan, Kyle B Walsh, Opeolu Adeoye, Julio A Landero-Figueroa
Stroke, a major cause of disability and mortality, affects someone in the United States every 40s. Stroke biomarkers, including those that could be used as a blood test for diagnosis of stroke, have been particularly elusive. We performed a double blind study to identify human plasma biomarkers for the diagnosis of stroke, including acute ischemic stroke (AIS) and intracerebral hemorrhage (ICH). We utilized a three-track approach based on the total metal profile, the metal cofactor levels among metalloproteins, and the identification of stroke-related metalloproteins...
July 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28592927/cost-utility-of-burns-management-in-nigeria-a-case-study-of-the-national-orthopaedic-hospital-enugu
#11
C E Okafor, O Onunka, L N Idoko
A major problem of burns is the high cost of management, as well as the discrimination and disability they can cause to patients. Maximising resource utilisation is of key importance for lower-middle-income countries (LMICs) like Nigeria. There is a need to know if Nigerian patients who were victims of burns get the best value for money. This study aimed to evaluate the average cost of managing burns in Nigeria, and determine if the treatment approach is cost-effective. The study was a cost-utility analysis from the perspective of health service providers in Nigeria, a case study of the National Orthopaedic Hospital Enugu (NOHE) using 2013 Microsoft excel...
March 31, 2017: Annals of Burns and Fire Disasters
https://www.readbyqxmd.com/read/28583165/validity-and-reliability-of-the-sri-lankan-version-of-the-kidney-disease-quality-of-life-questionnaire-kdqol-sf%C3%A2
#12
Sameera Senanayake, Nalika Gunawardena, Paba Palihawadana, Sanjeewa Kularatna, T S G Peiris
BACKGROUND: The disabling symptoms, various food and fluid restrictions, restrictions to social life and stigma and taboos attached to Chronic Kidney Disease (CKD), have shown to pose a significant bearing on a patient's Quality of Life (QOL). In the present study the Kidney Disease QOL-Short Form (KDQOL-SF™) was culturally adapted, modified and translated into Sinhala and validity and reliability were assessed. METHOD: The process to culturally adapt the Kidney Disease Specific Component (KDSC) of KDQOL-SF™ was carried out by the modified Delphi process with a group of experts...
June 5, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28582030/antiproliferative-drugs-for-restenosis-prevention
#13
REVIEW
Anwer Habib, Aloke Virmani Finn
Cardiovascular disease is a leading cause of death and disability worldwide. Current treatment strategies aimed at treating the symptoms and consequences of obstructive vascular disease have embraced both optimal medical therapy and catheter-based percutaneous coronary intervention with drug-eluting stents. Drug-eluting stents elute antiproliferative drugs inhibiting vascular smooth muscle cell proliferation, which occurs in response to injury and thus prevents restenosis. However, all drugs currently approved for use in drug-eluting stents do not discriminate between proliferating vascular smooth muscle cells and endothelial cells, thus delaying re-endothelialization and subsequent vascular healing...
July 2016: Interventional cardiology clinics
https://www.readbyqxmd.com/read/28579970/predicting-disability-after-ischemic-stroke-based-on-comorbidity-index-and-stroke-severity-from-the-virtual-international-stroke-trials-archive-acute-collaboration
#14
Thanh G Phan, Benjamin B Clissold, Henry Ma, John Van Ly, Velandai Srikanth
BACKGROUND AND AIM: The availability and access of hospital administrative data [coding for Charlson comorbidity index (CCI)] in large data form has resulted in a surge of interest in using this information to predict mortality from stroke. The aims of this study were to determine the minimum clinical data set to be included in models for predicting disability after ischemic stroke adjusting for CCI and clinical variables and to evaluate the impact of CCI on prediction of outcome. METHOD: We leverage anonymized clinical trial data in the Virtual International Stroke Trials Archive...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28579911/impact-of-the-lymphatic-filariasis-control-program-towards-elimination-of-filariasis-in-vanuatu-1997-2006
#15
Tammy Allen, Fasihah Taleo, Patricia M Graves, Peter Wood, George Taleo, Margaret C Baker, Mark Bradley, Kazuyo Ichimori
BACKGROUND: Lymphatic filariasis (LF) occurs when filarial parasites are transmitted to humans through mosquitoes. The filarial worms affect the lymphatic system which leads to abnormal enlargement of body parts, chronic pain, disability, and social discrimination. In 1999, a commitment was made to eliminate LF from the Pacific Region by 2010. The Pacific Program to Eliminate LF began, with Vanuatu being one of the 16 endemic countries included in this program. METHODS: In 1997/1998 a LF prevalence baseline survey was conducted to determine the need for mass drug administration (MDA) in Vanuatu...
2017: Tropical Medicine and Health
https://www.readbyqxmd.com/read/28572606/automated-screening-for-fragile-x-premutation-carriers-based-on-linguistic-and-cognitive-computational-phenotypes
#16
Arezoo Movaghar, Marsha Mailick, Audra Sterling, Jan Greenberg, Krishanu Saha
Millions of people globally are at high risk for neurodegenerative disorders, infertility or having children with a disability as a result of the Fragile X (FX) premutation, a genetic abnormality in FMR1 that is underdiagnosed. Despite the high prevalence of the FX premutation and its effect on public health and family planning, most FX premutation carriers are unaware of their condition. Since genetic testing for the premutation is resource intensive, it is not practical to screen individuals for FX premutation status using genetic testing...
June 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28570585/prevalence-of-depression-and-associated-clinical-and-socio-demographic-factors-in-people-living-with-lymphatic-filariasis-in-plateau-state-nigeria
#17
James Obindo, Jibril Abdulmalik, Emeka Nwefoh, Michael Agbir, Charles Nwoga, Aishatu Armiya'u, Francis Davou, Kurkat Maigida, Emmanuel Otache, Ajuma Ebiloma, Samuel Dakwak, John Umaru, Elisha Samuel, Christopher Ogoshi, Julian Eaton
BACKGROUND: Lymphatic filariasis is a chronic, disabling and often disfiguring condition that principally impacts the world's poorest people. In addition to the well-recognised physical disability associated with lymphedema and hydrocele, affected people often experience rejection, stigma and discrimination. The resulting emotional consequences are known to impact on the quality of life and the functioning of the affected individuals. However, the management of this condition has focused on prevention and treatment through mass drug administration, with scant attention paid to the emotional impact of the condition on affected individuals...
June 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28553694/investigation-of-different-classifiers-and-channel-configurations-of-a-mobile-p300-based-brain-computer-interface
#18
Simone A Ludwig, Jun Kong
Innovative methods and new technologies have significantly improved the quality of our daily life. However, disabled people, for example those that cannot use their arms and legs anymore, often cannot benefit from these developments, since they cannot use their hands to interact with traditional interaction methods (such as mouse or keyboard) to communicate with a computer system. A brain-computer interface (BCI) system allows such a disabled person to control an external device via brain waves. Past research mostly dealt with static interfaces, which limit users to a stationary location...
May 29, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28549403/perceived-social-support-as-a-moderator-between-perceived-discrimination-and-subjective-well-being-among-people-with-physical-disabilities-in-israel
#19
Michal Itzick, Maya Kagan, Patricia Tal-Katz
PURPOSE: Perceived social support has gained importance as a significant preventive factor of depressive symptoms and as helpful for rebuilding feelings of self-worth and subjective well-being among people with physical disabilities. The current study examined whether perceived social support moderates the association between perceived discrimination and subjective well-being among people with physical disabilities in Israel. MATERIALS AND METHODS: Data were collected by means of structured questionnaires among a convenience sample of 433 people with physical disabilities in Israel and hierarchical multiple regression was performed...
May 26, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28544303/a-systematic-review-of-the-evidence-regarding-cognitive-therapy-skills-that-assist-cognitive-behavioural-therapy-in-adults-who-have-an-intellectual-disability
#20
REVIEW
Patricia Cooney, Conall Tunney, Gary O'Reilly
BACKGROUND: Cognitive behavioural therapy (CBT) is being increasingly adapted for use with people who have an intellectual disability. However, it remains unclear whether inherent cognitive deficits that are present in adults who have an intellectual disability preclude the use of cognitive-based therapies. This review aims to systematically examine "cognitive therapy skills" in adults who have an intellectual disability that assist engagement in CBT. METHOD: Two authors independently reviewed titles and abstracts of articles located through electronic database searching...
May 24, 2017: Journal of Applied Research in Intellectual Disabilities: JARID
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