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https://www.readbyqxmd.com/read/29341180/risk-assessment-of-salmonellosis-from-consumption-of-alfalfa-sprouts-and-evaluation-of-the-public-health-impact-of-sprout-seed-treatment-and-spent-irrigation-water-testing
#1
Yuhuan Chen, Régis Pouillot, Sofia M Santillana Farakos, Steven Duret, Judith Spungen, Tong-Jen Fu, Fazila Shakir, Patricia A Homola, Sherri Dennis, Jane M Van Doren
We developed a risk assessment of human salmonellosis associated with consumption of alfalfa sprouts in the United States to evaluate the public health impact of applying treatments to seeds (0-5-log10 reduction in Salmonella) and testing spent irrigation water (SIW) during production. The risk model considered variability and uncertainty in Salmonella contamination in seeds, Salmonella growth and spread during sprout production, sprout consumption, and Salmonella dose response. Based on an estimated prevalence of 2...
January 16, 2018: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/29339579/conclusions-and-recommendations-from-the-17th-workshop-of-the-european-alara-network-alara-in-emergency-exposure-situations
#2
Sylvain Andresz, Julie Morgan, Pascal Croüail, Fernand Vermeersch
The European ALARA Network regularly organises workshops on topical issues in radiation protection. In light of the Fukushima accident, the most recent workshop questioned the application of the ALARA principle in emergency exposures situations. This memorandum presents the conclusions and recommendations of this workshop. One of the outcomes is that the process of optimisation in emergency exposure situations should be flexible enough to be able to modify or refine decisions over the course of an accident...
January 17, 2018: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29338871/likelihood-of-total-resolution-in-selective-comprehensive-two-dimensional-liquid-chromatography-with-parallel-processing-simulation-and-theory
#3
Joe M Davis, Dwight R Stoll
The probability Pr(sLC×LC) that all peaks are separated by a resolution of 1.5 or more in selective comprehensive two-dimensional liquid chromatography (sLC × LC) is computed for simple model systems of 5 to 60 peaks and first-dimension (1D) gradient times of 100 to 2000 s. The computations include mimics of a commercial instrument, whose fixed second-dimension (2D) gradient time and use of one cycle time for initialization reduces Pr(sLC×LC) relative to an earlier report. For serial sLC × LC, in which a single device collects and transfers 1D multiplets to the second dimension, Pr(sLC×LC) under practical conditions is predicted to be only slightly larger than the probability of total resolution in LC × LC for separations of the same duration in each case...
December 16, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29338148/novel-applications-of-bedside-monitoring-to-plumb-patient-hemodynamic-state-and-response-to-therapy
#4
Fabio Guarracino, Pietro Bertini, Michael R Pinsky
Hemodynamic monitoring is essential during the treatment of the critically ill in order to address the hemodynamic alterations and assess the response to treatment. Traditionally classified causes of shock and underlying pathophysiological mechanisms are often neglected by resuscitative strategies included in the guidelines. Most of hemodynamic management focuses on the ability to early recognise patients susceptible to increase cardiac output (CO) and mean arterial pressure (MAP) after a defined fluid challenge by eliciting Starling's law of the heart, and less is known of the ones presenting in shock and not volume responsive...
January 16, 2018: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29337079/rising-pco2-in-freshwater-ecosystems-has-the-potential-to-negatively-affect-predator-induced-defenses-in-daphnia
#5
Linda C Weiss, Leonie Pötter, Annika Steiger, Sebastian Kruppert, Uwe Frost, Ralph Tollrian
Anthropogenically released CO2 accumulates in the global carbon cycle and is anticipated to imbalance global carbon fluxes [1]. For example, increased atmospheric CO2 induces a net air-to-sea flux where the oceans take up large amounts of atmospheric CO2 (i.e., ocean acidification [2-5]). Research on ocean acidification is ongoing, and studies have demonstrated the consequences for ecosystems and organismal biology with major impacts on marine food webs, nutrient cycles, overall productivity, and biodiversity [6-9]...
January 9, 2018: Current Biology: CB
https://www.readbyqxmd.com/read/29336790/a-multiple-kernel-classification-approach-based-on-a-quadratic-successive-geometric-segmentation-methodology-with-a-fault-diagnosis-case
#6
Leonardo M Honório, Daniele A Barbosa, Edimar J Oliveira, Paulo A Nepomuceno Garcia, Murillo F Santos
This work presents a new approach for solving classification and learning problems. The Successive Geometric Segmentation technique is applied to encapsulate large datasets by using a series of Oriented Bounding Hyper Box (OBHBs). Each OBHB is obtained through linear separation analysis and each one represents a specific region in a pattern's solution space. Also, each OBHB can be seen as a data abstraction layer and be considered as an individual Kernel. Thus, it is possible by applying a quadratic discriminant function, to assemble a set of nonlinear surfaces separating each desirable pattern...
January 11, 2018: ISA Transactions
https://www.readbyqxmd.com/read/29336333/simulation-and-training-in-urology-in-collaboration-with-esu-esut
#7
Domenico Veneziano, Giovanni Cacciamani, Chandra Shekhar Biyani
Being a Surgeon today means taking on your shoulders countless responsibilities. It is definitely a high-stakes job but, even though the professionals do not go through the intense, focused and demanding training schedule as followed by the other equally risky fields, it doesn't yet require any practical training certification. Simulation was introduced in the aviation field in the early '30s with the "Link Trainer", designed to reproduce the most difficult flying case scenario: landing on an air-carrier. After almost a century, flight simulation is still becoming more sophisticated, while surgical training is slowly starting to fill the gap...
January 2018: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/29334979/measuring-spatial-accessibility-to-healthcare-services-with-constraint-of-administrative-boundary-a-case-study-of-yanqing-district-beijing-china
#8
Zhuolin Tao, Yang Cheng, Qingjing Zheng, Guicai Li
BACKGROUND: The two-step floating catchment area (2SFCA) method, which is one of the most widely used methods for measuring healthcare spatial accessibility, defines the catchment area of each facility as the area within a certain distance from the facility. However, in some cases, the service utilization behavior is constrained by administrative boundaries, therefore the definition of catchment area within a certain distance may be inappropriate. METHODS: In this study, we aim to propose a modification of the 2SFCA method for measuring spatial accessibility to healthcare services in a system constrained by administrative boundaries...
January 15, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29333029/flagellate-rash-an-unusual-complication-of-bleomycin-therapy-a-case-report-with-brief-review-of-literature
#9
Chaturbhuj Agrawal, Vineet Talwar, Rajeev Saini, Pradeep Babu
Chemotherapy-induced skin rashes are common toxicities encountered which require careful assessment and evaluation as rashes could be a manifestation of primary malignancy itself and a variety of drugs used in combination further complicate the clinical scenario. Bleomycin is an anticancer antibiotic derived from Streptomyces verticillus and has been commonly used in the treatment of Hodgkin's disease, germ cell tumors and for pleurodesis. There are various dermatological adverse effects of bleomycin which have been previously reported in literature including skin peeling, hyperkeratosis, nail bed changes, Raynaud's phenomenon, and palmoplantar desquamation...
October 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29331246/estimation-of-expected-dengue-seroprevalence-from-passive-epidemiological-surveillance-systems-in-selected-areas-of-argentina-a-proxy-to-evaluate-the-applicability-of-dengue-vaccination
#10
Pablo Orellano, Darío Vezzani, Nancy Quaranta, Julieta Reynoso, Oscar Daniel Salomón
BACKGROUND: Current recommendations about dengue vaccination by the World Health Organization depend on seroprevalence levels and serological status in populations and individuals. However, seroprevalence estimation may be difficult due to a diversity of factors. Thus, estimation through models using data from epidemiological surveillance systems could be an alternative procedure to achieve this goal. OBJECTIVE: To estimate the expected dengue seroprevalence in children of selected areas in Argentina, using a simple model based on data from passive epidemiological surveillance systems...
January 11, 2018: Vaccine
https://www.readbyqxmd.com/read/29329053/long-term-safety-area-tracking-lt-sat-with-online-failure-detection-and-recovery-for-robotic-minimally-invasive-surgery
#11
Veronica Penza, Xiaofei Du, Danail Stoyanov, Antonello Forgione, Leonardo S Mattos, Elena De Momi
Despite the benefits introduced by robotic systems in abdominal Minimally Invasive Surgery (MIS), major complications can still affect the outcome of the procedure, such as intra-operative bleeding. One of the causes is attributed to accidental damages to arteries or veins by the surgical tools, and some of the possible risk factors are related to the lack of sub-surface visibilty. Assistive tools guiding the surgical gestures to prevent these kind of injuries would represent a relevant step towards safer clinical procedures...
December 22, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/29327991/a-clinical-librarian-embedded-in-medical-education-patient-centered-encounters-for-preclinical-medical-students
#12
Lindsay Blake, Frances M Yang, Hutton Brandon, Benjamin Wilson, Renee Page
Adding patient encounters and simulation to the preclinical years of medical school is becoming increasingly popular. This article describes the creation of active learning opportunities by a clinical librarian that are aimed at training preclinical students through the use of simulated patient scenarios. Scenarios for second-year students walk them through the evidence-based resources needed in clinical years and beyond through a standardized patient encounter. Scenarios for first-year students involve role-play of cases where the patient and physician bring contrasting ideas to the outpatient interaction...
January 2018: Medical Reference Services Quarterly
https://www.readbyqxmd.com/read/29324723/error-recovery-in-the-time-triggered-paradigm-with-ftt-can
#13
Luis Marques, Verónica Vasconcelos, Paulo Pedreiras, Luís Almeida
Data networks are naturally prone to interferences that can corrupt messages, leading to performance degradation or even to critical failure of the corresponding distributed system. To improve resilience of critical systems, time-triggered networks are frequently used, based on communication schedules defined at design-time. These networks offer prompt error detection, but slow error recovery that can only be compensated with bandwidth overprovisioning. On the contrary, the Flexible Time-Triggered (FTT) paradigm uses online traffic scheduling, which enables a compromise between error detection and recovery that can achieve timely recovery with a fraction of the needed bandwidth...
January 11, 2018: Sensors
https://www.readbyqxmd.com/read/29324265/bayesian-spatiotemporal-crash-frequency-models-with-mixture-components-for-space-time-interactions
#14
Wen Cheng, Gurdiljot Singh Gill, Yongping Zhang, Zhong Cao
The traffic safety research has developed spatiotemporal models to explore the variations in the spatial pattern of crash risk over time. Many studies observed notable benefits associated with the inclusion of spatial and temporal correlation and their interactions. However, the safety literature lacks sufficient research for the comparison of different temporal treatments and their interaction with spatial component. This study developed four spatiotemporal models with varying complexity due to the different temporal treatments such as (I) linear time trend; (II) quadratic time trend; (III) Autoregressive-1 (AR-1); and (IV) time adjacency...
January 8, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29322542/a-nonparametric-method-to-detect-increased-frequencies-of-adverse-drug-reactions-over-time
#15
Günter Heimann, Rossella Belleli, Jouni Kerman, Roland Fisch, Joseph Kahn, Sigrid Behr, Conny Berlin
Signal detection is routinely applied to spontaneous report safety databases in the pharmaceutical industry and by regulators. As an example, methods that search for increases in the frequencies of known adverse drug reactions for a given drug are routinely applied, and the results are reported to the health authorities on a regular basis. Such methods need to be sensitive to detect true signals even when some of the adverse drug reactions are rare. The methods need to be specific and account for multiplicity to avoid false positive signals when the list of known adverse drug reactions is long...
January 10, 2018: Statistics in Medicine
https://www.readbyqxmd.com/read/29321363/dominance-effects-estimation-of-tlr4-and-cacna2d1-genes-for-health-and-production-traits-using-logistic-regression
#16
Masoumeh Bagheri, Azadeh Zahmatkesh
Knowledge of nonadditive variance and genetic effects can be helpful in explaining the total genetic variation formost of the traits. The objective of this study was to estimate dominance effects of several single-nucleotide polymorphism (SNP) genotypes for the production traits and clinical mastitis residual (CMR), in Holstein dairy cattle in a case-control study. Records of 305 days lactation were obtained for production traits and CMR. Animals were selected based on extreme values for CMR from mixed model analyses...
December 2017: Journal of Genetics
https://www.readbyqxmd.com/read/29319894/antibiotic-prescribing-for-endodontic-therapies-a-comparative-survey-between-general-dental-practitioners-gdps-and-final-year-bachelor-of-dental-surgery-bds-students-in-cardiff-uk
#17
A A Al Masan, P M H Dummer, D J J Farnell, M E Vianna
AIM: To evaluate the views of final-year dental surgery (BDS; G1) students at Cardiff University and general dental practitioners (GDPs; G2) within the city of Cardiff, Wales on antibiotic prescribing for endodontic conditions, and investigate the potential differences between the two groups. METHODS: A cross-sectional online questionnaire-based survey of 12 qualitative and quantitative questions was distributed to 76 final-year BDS Cardiff University students and 55 dental practices within Cardiff, UK...
January 10, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29317937/evaluating-the-potential-for-pharmacists-to-prescribe-oral-anticoagulants-for-atrial-fibrillation
#18
Roopinder K Sandhu, Lisa M Guirguis, Tammy J Bungard, Erik Youngson, Lisa Dolovich, Jamie C Brehaut, Jeff S Healey, Finlay A McAlister
Background: Oral anticoagulant therapy (OAC) to prevent atrial fibrillation (AF)-related strokes remains poorly used. Alternate strategies, such as community pharmacist prescribing of OAC, should be explored. Methods: Approximately 400 pharmacists, half with additional prescribing authority (APA), randomly selected from the Alberta College of Pharmacists, were invited to participate in an online survey over a 6-week period. The survey consisted of demographics, case scenarios assessing appropriateness of OAC (based on the 2014 Canadian Cardiovascular Society AF guidelines) and perceived barriers to prescribing...
January 2018: Canadian Pharmacists Journal: CPJ, Revue des Pharmaciens du Canada: RPC
https://www.readbyqxmd.com/read/29316693/use-of-savitzky-golay-filter-for-performances-improvement-of-shm-systems-based-on-neural-networks-and-distributed-pzt-sensors
#19
Mario A de Oliveira, Nelcileno V S Araujo, Rodolfo N da Silva, Tony I da Silva, Jayantha Epaarachchi
A considerable amount of research has focused on monitoring structural damage using Structural Health Monitoring (SHM) technologies, which has had recent advances. However, it is important to note the challenges and unresolved problems that disqualify currently developed monitoring systems. One of the frontline SHM technologies, the Electromechanical Impedance (EMI) technique, has shown its potential to overcome remaining problems and challenges. Unfortunately, the recently developed neural network algorithms have not shown significant improvements in the accuracy of rate and the required processing time...
January 8, 2018: Sensors
https://www.readbyqxmd.com/read/29316636/segmentation-of-gait-sequences-in-sensor-based-movement-analysis-a-comparison-of-methods-in-parkinson-s-disease
#20
Nooshin Haji Ghassemi, Julius Hannink, Christine F Martindale, Heiko Gaßner, Meinard Müller, Jochen Klucken, Björn M Eskofier
Robust gait segmentation is the basis for mobile gait analysis. A range of methods have been applied and evaluated for gait segmentation of healthy and pathological gait bouts. However, a unified evaluation of gait segmentation methods in Parkinson's disease (PD) is missing. In this paper, we compare four prevalent gait segmentation methods in order to reveal their strengths and drawbacks in gait processing. We considered peak detection from event-based methods, two variations of dynamic time warping from template matching methods, and hierarchical hidden Markov models (hHMMs) from machine learning methods...
January 6, 2018: Sensors
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