Yading Li, Mingxian Zheng, Yi Wang, Gaofan Xu, Yunyun He, Yue Wu, Xiao Wang, Yuyang Liu, Yujie Jiang, Xiaowen Liu, Yangyang Meng, Yixuan Yap, Shengliang Zhu, Cong He, Bingduo Zhou
Background: Laryngopharyngeal reflux disease (LPRD) is an extraesophageal syndromic manifestation of gastroesophageal reflux disease (GERD). Despite the increasing incidence of and concern about LPRD, treatment with proton pump inhibitors (PPIs) is unsatisfactory. Here, LPRD was treated with Tonghua Liyan (THLY) granules in combination with PPIs to evaluate treatment efficacy and possible adverse reactions. Methods: Seventy-six LPRD patients with stagnation of phlegm and qi syndrome (SPQS) were randomly divided into an experimental group and a control group...
2024: Frontiers in Pharmacology