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Jason K Hou, Christoph Gasche, Noam Z Drazin, Sarah Alandra Weaver, Orna G Ehrlich, Ridhima Oberai, Sophie Zapala, Corey A Siegel, Gil Melmed
BACKGROUND: Anemia is a common complication among patients with inflammatory bowel diseases (IBD) and is associated with high rates of IBD-related complications, resource utilization, and impaired quality of life. Despite practice guidelines for anemia in patients with IBD, gaps remain in the perceptions of anemia among health care providers. The aims of this study were to identify gaps in care and to develop a care pathway for anemia in patients with IBD. METHODS: The Crohn's & Colitis Foundation of America anemia care pathway was developed by a committee using principles of cognitive task analysis...
September 30, 2016: Inflammatory Bowel Diseases
Sarkis Kiramijyan, Romain Didier, Edward Koifman, Smita I Negi
BACKGROUND: It has become challenging for cardiovascular fellows-in-training (FIT) to determine which national cardiovascular conference (NCC) to attend given the broad range of meetings and the breadth of information offered. The aim of this study was to report our own experiences of the utility and individual strengths of the NCCs and to further understand the interventional cardiology (IC) FITs' viewpoint regarding the benefits of the individual NCCs. METHODS: A survey was formulated with questions and scenarios regarding topics deemed to be of highest importance for an IC-FIT...
October 2016: Cardiovascular Revascularization Medicine: Including Molecular Interventions
Amit Odelia, Joffe Erel, Perry Chava, Herishanu Yair, Sarid Nadav, Lishner Michael, Avivi Irit
INTRODUCTION: Due to the rarity of lymphoma during pregnancy, management guidelines are based upon evidence from retrospective studies and case reports. Here, we review the major dilemmas in the field and examine the approach of hemato-oncologists in Israel to the management of lymphoma in pregnancy. METHODOLOGY: We performed a literature search on the PubMed database using keywords for all papers on the subject from 1990-2014. The papers were reviewed by an expert panel who devised a questionnaire covering the main dilemmas...
October 14, 2016: International Journal of Clinical Oncology
Zhu-Feng Geng, Kai Yang, Yin-Ping Li, Shan-Shan Guo, Chun-Xue You, Wen-Juan Zhang, Zhe Zhang, Shu-Shan Du
One sulphur-containing amide (N-[2-(4-Hydroxyphenyl)-ethyl]-3-methanesulfonyl-N-methyl-propionamide) which was isolated from Glycosmis lucida Wall ex Huang had a different NMR profile with this kind of compounds' normal case. Based on the information obtained by nuclear magnetic resonance pectroscopy (NMR) and mass spectrometry (MS), its configurations in solution were investigated. The results indicated that the compound would have two stable configurations in solution as the double bond switched between C-N and C-O in an appropriate rate...
October 14, 2016: Natural Product Research
Karla Köpke, Kerstin Prahm, Silke Buda, Walter Haas
BACKGROUND: Every year epidemic waves of influenza and other acute respiratory infections (ARIs) cause a highly variable burden of disease in the population. Thus, assessment of the situation and adaptation of prevention strategies have to rely on real time syndromic surveillance. OBJECTIVE: We have established an ICD-10-based electronic system allowing rapid capture and transmission of information on ARI (SEED(ARI)), in Germany. Here we report the evaluation of this new system based on results of the syndromic and virologic surveillance carried out by the working group on influenza in Germany (AGI)...
October 13, 2016: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Peter Nicklen, Jennifer L Keating, Stephen Maloney
BACKGROUND: Case-based learning (CBL) is an educational approach where students work in small, collaborative groups to solve problems. Web-conferencing software provides a platform to present information and share concepts that are vital to CBL. Previous studies have found that participants were resistant to change associated with implementing e-learning; however, strategies to reduce this resistance have not been explored. OBJECTIVE: This study was designed to explore student preconceptions and understanding of remote-online case-based learning (RO-CBL)...
April 28, 2016: JMIR Med Educ
Peter Nicklen, Jennifer L Keating, Stephen Maloney
BACKGROUND: Case-based learning (CBL) typically involves face-to-face interaction in small collaborative groups with a focus on self-directed study. To our knowledge, no published studies report an evaluation of Web conferencing in CBL. OBJECTIVE: The primary aim of this study was to explore student perceptions and attitudes in response to a remote-online case-based learning (RO-CBL) experience. METHODS: This study took place over a 2-week period in 2013 at Monash University, Victoria, Australia...
March 22, 2016: JMIR Med Educ
Fabrizio Galimberti, Natasha Atanaskova Mesinkovska
Certain vitamin and mineral deficiencies may be recognized by their cutaneous signs. This case-based article reviews deficiencies of zinc and vitamins A, B2, B3, B6, and C, discussing their consequences and skin findings.
October 2016: Cleveland Clinic Journal of Medicine
Kerri A Thom, Emily L Heil, Lindsay D Croft, Alison Duffy, Daniel J Morgan, Mary Johantgen
Clinical errors are common and can lead to adverse events and patient death. Health professionals must work within interprofessional teams to provide safe and effective care to patients, yet current curricula is lacking with regards to interprofessional education and patient safety. We describe the development and implementation of an interprofessional course aimed at medical, nursing, and pharmacy learners during their clinical training at a large academic medical centre. The course objectives were based on core competencies for interprofessional education and patient safety...
August 11, 2016: Journal of Interprofessional Care
Luc Morin, Samiran Ray, Clare Wilson, Solenn Remy, Mohamed Rida Benissa, Nicolaas J G Jansen, Etienne Javouhey, Mark J Peters, Martin Kneyber, Daniele De Luca, Simon Nadel, Luregn Jan Schlapbach, Graeme Maclaren, Pierre Tissieres
PURPOSE: Although overall paediatric septic shock mortality is decreasing, refractory septic shock (RSS) is still associated with high mortality. A definition for RSS is urgently needed to facilitate earlier identification and treatment. We aim to establish a European society of paediatric and neonatal intensive care (ESPNIC) experts' definition of paediatric RSS. METHODS: We conducted a two-round Delphi study followed by an observational multicentre retrospective study...
October 5, 2016: Intensive Care Medicine
Shahram Tahmasebian, Mostafa Langarizadeh, Marjan Ghazisaeidi, Mitra Mahdavi-Mazdeh
INTRODUCTION: Case-based reasoning (CBR) systems are one of the effective methods to find the nearest solution to the current problems. These systems are used in various spheres as well as industry, business, and economy. The medical field is not an exception in this regard, and these systems are nowadays used in the various aspects of diagnosis and treatment. METHODOLOGY: In this study, the effective parameters were first extracted from the structured discharge summary prepared for patients with chronic kidney diseases based on data mining method...
July 16, 2016: Acta Informatica Medica: AIM
Marie-Andrée Jacob
Violations of research integrity are understood to have wide-ranging negative consequences for the trustworthiness of science and the health of the public. My goal in this article is not to cause further outrage about research misconduct. Instead, this article queries research conducts expressly as seen through the eyes of a specific regulator and over a specific period (1990-2015). The result is an assessment of the strengths and limitations of the application of the General Medical Council's (GMC's) fitness to practice model in this area...
October 5, 2016: Medical Law Review
Enos O Masini, Omar Mansour, Clare E Speer, Vittorio Addona, Christy L Hanson, Joseph K Sitienei, Hillary K Kipruto, Martin Muhingo Githiomi, Brenda Nyambura Mungai
Despite high tuberculosis (TB) treatment success rate, treatment adherence is one of the major obstacles to tuberculosis control in Kenya. Our objective was to identify patient-related factors that were associated with time to TB treatment interruption and the geographic distribution of the risk of treatment interruption by county. Data of new and retreatment patients registered in TIBU, a Kenyan national case-based electronic data recording system, between 2013 and 2014 was obtained. Kaplan-Meier curves and log rank tests were used to assess the adherence patterns...
2016: PloS One
Daniel Rodriguez Muñoz, Gonzalo Alonso Salinas, Eduardo Franco Diez, Javier Moreno, Roberto Matía Francés, Antonio Hernández-Madrid, José Zamorano
No abstract text is available yet for this article.
October 5, 2016: International Journal of Medical Education
Aryna Zanuzdana, Karla Köpke, Walter Haas
Influenza and community-acquired pneumonia (CAP) impose a considerable annual burden on the German primary care system. Yet there is a lack of epidemiological data from the country's outpatient sector on groups at risk as well as on the complications of these diseases.The Robert Koch Institute (RKI) initiated the study to identify population groups at increased risk for influenza or CAP as well as related comorbidities and sequelae. We present the methodology of the study and the descriptive analysis of the patients...
September 30, 2016: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Angela Hua, Kaushal H Shah, Manish Garg, Eric Legome, Jacob Ufberg
Hanging has become the second most common form of successful suicide in the United States. Along with a high mortality rate, the long-term morbidity is consequential for both the individual patient and society. A thorough knowledge of the clinical approach will assist the emergency physician in providing optimal care and helping to minimize delayed respiratory complications. Using a case-based scenario, the initial management strategies along with rational evidence-based treatments are reviewed.
September 29, 2016: Journal of Emergency Medicine
Sieun Lee, Nicolas Charon, Benjamin Charlier, Karteek Popuri, Evgeniy Lebed, Marinko V Sarunic, Alain Trouvé, Mirza Faisal Beg
We propose a novel approach for quantitative shape variability analysis in retinal optical coherence tomography images using the functional shape (fshape) framework. The fshape framework uses surface geometry together with functional measures, such as retinal layer thickness defined on the layer surface, for registration across anatomical shapes. This is used to generate a population mean template of the geometry-function measures from each individual. Shape variability across multiple retinas can be measured by the geometrical deformation and functional residual between the template and each of the observations...
September 20, 2016: Medical Image Analysis
Eri Watanabe, Hitoshi Sugawara, Takeshi Yamashita, Akira Ishii, Aya Oda, Chihiro Terai
We report the case of a 71-year-old Japanese woman with adult-onset Still's disease (AOSD) in whom macrophage activation syndrome (MAS) developed despite therapy with oral high-dose prednisolone and intravenous methylprednisolone pulse therapy twice. She was successfully treated with tocilizumab (TCZ). Soon afterward, her fever ceased and high levels of both ferritin and C-reactive protein levels decreased. Her course was complicated by disseminated intravascular coagulation, cytomegalovirus infection, and Pneumocystis jirovecii pneumonia...
2016: Case Reports in Medicine
(no author information available yet)
Serum lactate levels are frequently measured in patients with undifferentiated conditions in emergency departments. This article uses a case-based reflection to analyse the role of lactate measurement in these patients. It examines the rationale for testing and the potential causes of raised levels, to remind clinicians that this diagnostic intervention must be taken in the context of patients' clinical presentations and not in isolation.
September 30, 2016: Nursing Management (Harrow)
B Ramasubbu, A Donnelly, A Moughty
A retrospective review of the demographics, co-morbidities and substance misuse of the 20 most frequent presenters to the Mater Misericordiae University Hospital emergency department during 2014 was carried out in an attempt to better understand the epidemiology of their presentations. Eighty-five percent were male and 15% female (p<0.001). The average age was 40.6 years with a median 38.5 years. All were unemployed and 7 (35%) had no fixed abode. Thirteen patients (65%) lived an average of 4.5 kilometres from the ED...
2016: Irish Medical Journal
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