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Sepsis care

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https://www.readbyqxmd.com/read/28091436/acute-kidney-injury-in-lagos-pattern-outcomes-and-predictors-of-in-hospital-mortality
#1
B T Bello, A A Busari, C O Amira, Y R Raji, R W Braimoh
CONTEXT: The pattern of acute kidney injury (AKI) differs significantly between developed and developing countries. AIMS: The aim of th study was to determine the pattern and clinical outcomes of AKI in Lagos, Southwest Nigeria. SETTINGS AND DESIGN: A retrospective review of hospital records of all patients with a diagnosis of AKI over a 20-month period. SUBJECTS AND METHODS: Records of 54 patients were reviewed. Information retrieved included, bio-data, etiology of AKI, results of laboratory investigations, and patient outcomes...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28088587/late-onset-neonatal-sepsis-in-arab-states-in-the-gulf-region-two-year-prospective-study
#2
Majeda S Hammoud, Abdullah Al-Taiar, Sameer Y Al-Abdi, Hussain Bozaid, Anwar Khan, Laila M AlMuhairi, Moghis Ur Rehman
OBJECTIVES: This study aimed to investigate the incidence of Late-Onset Sepsis (LOS) in neonatal intensive care units (NICUs) in Arab states in the gulf region and describe the main causative organisms and their antibiotic resistance. METHODS: Observational prospective cohort study was conducted over two-year period in five NICUs in Kuwait, Saudi Arabia and United Arab Emirates. LOS was defined as the growth of a single potentially pathogenic organism from blood or cerebrospinal fluid in infants >3days of age with clinical and laboratory findings consistent with infection...
January 11, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28087409/thioredoxin-a-novel-biomarker-of-post-injury-sepsis
#3
Jesper Eriksson, Andreas Gidlöf, Mikael Eriksson, Emma Larsson, Olof Brattström, Anders Oldner
BACKGROUND: Thioredoxin (TRX), an endogenous anti-oxidant protein induced in inflammatory conditions, has been shown to increase in plasma and to be associated with outcome in septic patients. This biomarker has never been studied in a trauma setting. We hypothesized that TRX would be increased after trauma and associated with post-injury sepsis. METHODS: Single-centre prospective observational study conducted at the intensive care unit (ICU) at the Karolinska University Hospital, Stockholm, Sweden, a level-1 trauma centre...
January 10, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28079606/relationship-between-alternative-resuscitation-strategies-host-response-and-injury-biomarkers-and-outcome-in-septic-shock-analysis-of-the-protocol-based-care-for-early-septic-shock-study
#4
John A Kellum, Francis Pike, Donald M Yealy, David T Huang, Nathan I Shapiro, Derek C Angus
OBJECTIVES: The Protocol-based Care for Early Septic Shock trial found no differences across alternative resuscitation strategies in all-cause mortality. A separate aim was to determine whether differences in resuscitation strategies affected trajectories of biomarkers of key pathways associated with downstream clinical outcomes of sepsis and whether there were differences in survival across treatment arms for patients with different baseline biomarker profiles. DESIGN: Secondary analysis of a large randomized clinical trial...
January 10, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28079604/prior-use-of-calcium-channel-blockers-is-associated-with-decreased-mortality-in-critically-ill-patients-with-sepsis-a-prospective-observational-study
#5
Maryse A Wiewel, Lonneke A van Vught, Brendon P Scicluna, Arie J Hoogendijk, Jos F Frencken, Aeilko H Zwinderman, Janneke Horn, Olaf L Cremer, Marc J Bonten, Marcus J Schultz, Tom van der Poll
OBJECTIVES: Experimental studies suggest that calcium channel blockers can improve sepsis outcome. The aim of this study was to determine the association between prior use of calcium channel blockers and the outcome of patients admitted to the ICU with sepsis. DESIGN: A prospective observational study. SETTING: The ICUs of two tertiary care hospitals in the Netherlands. PATIENTS: In total, 1,060 consecutive patients admitted with sepsis were analyzed, 18...
January 10, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28079172/25-oh-d-and-1-25-oh-d-vitamin-d-fails-to-predict-sepsis-and-mortality-in-a-prospective-cohort-study
#6
Franz Ratzinger, Helmuth Haslacher, Markus Stadlberger, Ralf L J Schmidt, Markus Obermüller, Klaus G Schmetterer, Thomas Perkmann, Athanasios Makristathis, Rodrig Marculescu, Heinz Burgmann
The clinical role of vitamin D in sepsis and mortality prediction is controversially discussed. Therefore, we conducted a prospective cohort study on standard care wards, including 461 patients with suspected sepsis fulfilling two or more SIRS criteria. On the first and third day after onset of SIRS symptoms levels of 25(OH)D, 1,25(OH)D and sepsis biomarkers were analysed for their predictive capacity for identifying infection, bacteraemia and an elevated mortality risk. Additionally, several SNPs associated with vitamin D metabolism were evaluated...
January 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28078833/clinical-profile-and-outcome-of-patients-with-severe-sepsis-treated-in-an-intensive-care-unit-in-india
#7
T T Paary, M S Kalaiselvan, M K Renuka, A S Arunkumar
Introduction: Sepsis is the leading cause of intensive care unit (ICU) admissions and is associated with high mortality. Objectives: To identify the incidence, risk factors and outcome of patients with severe sepsis and septic shock. Methods: A prospective observational study was done in a multidisciplinary ICU over a period of 18 months. We included all adult patients admitted to ICU with features of severe sepsis and septic shock as per SCCM/ACCP guidelines...
30, 2016: Ceylon Medical Journal
https://www.readbyqxmd.com/read/28076304/the-use-of-liquid-chromatography-tandem-mass-spectrometry-for-therapeutic-drug-monitoring-of-antibiotics-in-cancer-patients
#8
Nahed El-Najjar, Jonathan Jantsch, André Gessner
Cancer remains a leading cause of mortality and morbidity worldwide. In addition to organ failure, the most frequent reasons for admission of cancer patients to intensive care units (ICU) are: infections and sepsis. As critically ill, the complexity of the health situation of cancer patients renders the standard antimicrobial regimen more complex and even inadequate which results in increased mortality rates. This is due to pathophysiological changes in the volume of distribution, increased clearance, as well as to organ dysfunction...
January 11, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28074416/proceedings-of-r%C3%A3-animation-2017-the-french-intensive-care-society-international-congress
#9
Chtara Kamilia, Kais Regaieg, Najeh Baccouch, Hedi Chelly, Mabrouk Bahloul, Mounir Bouaziz, Ali Jendoubi, Ahmed Abbes, Houda Belhaouane, Oussama Nasri, Layla Jenzri, Salma Ghedira, Mohamed Houissa, Kamal Belkadi, Youness Harti, Afak Nsiri, Khalid Khaleq, Driss Hamoudi, Rachid Harrar, Camille Thieffry, Frédéric Wallet, Erika Parmentier-Decrucq, Raphaël Favory, Daniel Mathieu, Julien Poissy, Thomas Lafon, Philippe Vignon, Emmanuelle Begot, Alexandra Appert, Mathilde Hadj, Paul Claverie, Morgan Matt, Olivier Barraud, Bruno François, Amira Jamoussi, Amira Ben Jazia, Takoua Marhbène, Dhouha Lakhdhar, Jalila Ben Khelil, Mohamed Besbes, Julien Goutay, Caroline Blazejewski, Isabelle Joly-Durand, Isabelle Pirlet, Marie Pierre Weillaert, Sebastien Beague, Soufi Aziz, Reda Hafiane, Khalid Hattabi, Mohamed Aziz Bouhouri, Driss Hammoudi, Abdelaziz Fadil, Rachid Al Harrar, Khalid Zerouali, Fatma Kaaniche Medhioub, Rania Allela, Najla Ben Algia, Samar Cherif, Mohamed Taoufik Slaoui, Souhail Boubia, Y Hafiani, A Khaoudi, R Cherkab, W Elallam, C Elkettani, L Barrou, M Ridaii, Rihi El Mehdi, Caroline Schimpf, Assaf Mizrahi, Benoît Pilmis, Alban Le Monnier, Kelly Tiercelet, Mélanie Cherin, Cédric Bruel, Francois Philippart, Sébastien Bailly, Jc Lucet, Alain Lepape, François L'hériteau, Martine Aupée, Caroline Bervas, Sandrine Boussat, Anne Berger-Carbonne, Anaïs Machut, Anne Savey, Jean-François Timsit, Keyvan Razazi, Jérémy Rosman, Nicolas de Prost, Guillaume Carteaux, Chloe Jansen, Jean Winoc Decousser, Christian Brun-Buisson, Armand Mekontso Dessap, Aymen M'rad, Zouhour Ouali, Manel Barghouth, Achille Kouatchet, Rafael Mahieu, Emmanuel Weiss, David Schnell, Jean-Ralph Zahar, Margaux Artiguenave, Paktoris-Papine Sophie, Florence Espinasse, Faten El Sayed, Aurélien Dinh, Cyril Charron, Guillaume Geri, Antoine Vieillard-Baron, Xavier Repessé, Hatem Kallel, Claire Mayence, Stéphanie Houcke, Pascal Guegueniat, Didier Hommel, Kaouther Dhifaoui, Zied Hajjej, Amira Fatnassi, Walid Sellami, Iheb Labbene, Mustapha Ferjani, Fahmi Dachraoui, Sabrine Nakkaa, Abdelwaheb M'ghirbi, Ali Adhieb, Dhouha Ben Braiek, Kmar Hraiech, Ali Ousji, Islem Ouanes, Hammouda Zaineb, Saousen Ben Abdallah, Lamia Ouanes-Besbes, Fekri Abroug, Simon Klein, Mattéo Miquet, Jean-Marc Thouret, Vincent Peigne, Jean-Louis Daban, Mathieu Boutonnet, Bernard Lenoir, Takoua Merhbene, Celine Derreumaux, Thierry Seguin, Jean-Marie Conil, Charlotte Kelway, Valery Blasco, Cyril Nafati, Karim Harti, Laurent Reydellet, Jacques Albanese, Narjess Ben Aicha, Khaoula Meddeb, Ahmed Khedher, Jihene Ayachi, Nesrine Fraj, Nesrine Sma, Imed Chouchene, Mohamed Boussarsar, Soumaya Ben Yedder, Walid Samoud, Bousselmi Radhouene, Bousselmi Mariem, Asma Ammar, Asma Ben Cheikh, Hend Ben Lakhal, Messaouda Khelfa, Yamina Hamdaoui, Nabiha Bouafia, Timothée Trampont, Thomas Daix, Vincent Legarçon, Henri Hani Karam, Nicolas Pichon, Fatma Essafi, Nasreddine Foudhaili, Hafedh Thabet, Youssef Blel, Nozha Brahmi, Hanane Ezzouine, Mahmoud Kerrous, Saad El Haoui, Soufiane Ahdil, Abdellatif Benslama, Khalid Abidi, Tarek Dendane, Ssouni Oussama, Jihane Belayachi, Naoufal Madani, Redouane Abouqal, Amine Ali Zeggwagh, Hatem Ghadhoune, Anis Chaari, Guissouma Jihene, Hend Allouche, Insaf Trabelsi, Habib Brahmi, Mohamed Samet, Hatem El Ghord, Ben Sik Ali Habiba, Nouira Hajer, Najla Tilouch, Sondes Yaakoubi, Oussama Jaoued, Rim Gharbi, Mohamed Fekih Hassen, Souheil Elatrous, Julien Arcizet, Bertrand Leroy, Caroline Abdulmalack, Catherine Renzullo, Maël Hamet, Jean-Marc Doise, Jérôme Coutet, Chaigar Mohammed Cheikh, Zakaria Quechar, Magalie Joris, Dimitri Titeca Beauport, Loay Kontar, Delphine Lebon, Bérengère Gruson, Michel Slama, Jean-Pierre Marolleau, Julien Maizel, Julie Gorham, Lieveke Ameye, Thierry Berghmans, Marianne Paesmans, Jean-Paul Sculier, Anne-Pascale Meert, Max Guillot, Marie-Pierre Ledoux, Thierry Braun, Quentin Maestraggi, Baptiste Michard, Vincent Castelain, Raoul Herbrecht, Francis Schneider, Severine Couffin, David Lobo, Nicolas Mongardon, Gilles Dhonneur, Roman Mounier, Pierrick Le Borgne, Sophie Couraud, Jean-Etienne Herbrecht, Alexandra Boivin, François Lefebvre, Pascal Bilbault, Setti-Aouicha Zelmat, Djamila-Djahida Batouche, Fatima Mazour, Belkacem Chaffi, Nadia Benatta, Ali Habiba Sik, I Talik, Maxime Perrier, Eliane Gouteix, Claude Koubi, Annabelle Escavy, Victoria Guilbaut, Jean-Philippe Fosse, Rahma Ben Jazia, Ahmed Abdelghani, Pierre-Julien Cungi, Julien Bordes, Cédric Nguyen, Candice Pierrou, Maximilien Cruc, Alain Benois, Frédéric Duprez, Thierry Bonus, Grégory Cuvelier, Sandra Ollieuz, Sharam Machayekhi, Frédéric Paciorkowski, Gregory Reychler, Remi Coudroy, Arnaud W Thille, Xavier Drouot, Véronique Diaz, Jean-Claude Meurice, René Robert, Olfa Turki, Hmida Chokri Ben, Mona Assefi, Romain Deransy, Hélène Brisson, Antoine Monsel, Filomena Conti, Olivier Scatton, Olivier Langeron, Hassen Ben Ghezala, Salah Snouda, Chiekh Imen Ben, Moez Kaddour, Anwar Armel, Lafrikh Youness, Bensaid Abdelhak, Miloudi Youssef, Al Harrar Najib, Amouzoun Mustapha, Mtioui Noufel, Zamd Mohamed, El Khayat Salma, Medkouri Ghizlane, Benghanam Mohamed, Ramdani Benyounes, Florent Montini, Sébastien Moschietto, Emilien Gregoire, Guillaume Claisse, Julien Guiot, Philippe Morimont, Jean-Marie Krzesinski, Christophe Mariat, Bernard Lambermont, Etienne Cavalier, Pierre Delanaye, Soumia Benbernou, Sofiane Ilies, Abdelkader Azza, Khalida Bouyacoub, Meriem Louail, Houria Mokhtari-Djebli, Romain Arrestier, Fabrice Daviaud, Xavier Laborne Francois, Elsa Brocas, Gérald Choukroun, Oscar Peñuelas, José-Angel Lorente, Pablo Cardinal-Fernandez, José-Maria Rodriguez, José-Antonio Aramburu, Andres Esteban, Fernando Frutos-Vivar, Laurent Bitker, Nicolas Costes, Didier Le Bars, Franck Lavenne, Mojgan Devouassoux, Jean-Christophe Richard, Malika Mechati, Marc Gainnier, Laurent Papazian, Christophe Guervilly, Aude Garnero, Jean Michel Arnal, Hadrien Roze, Jean Christophe Richard, Benjamin Repusseau, Antoine Dewitte, Olivier Joannes-Boyau, Alexandre Ouattara, Nadia Harbouze, A M Amine, A G Olandzobo, Alexandre Herbland, Marie Richard, Nicolas Girard, Lucile Lambron, Olivier Lesieur, Sarah Wainschtein, Sidonie Hubert, Albane Hugues, Marc Tran, Philippe Bouillard, Vlad Loteanu, Maxime Leloup, Alexandra Laurent, Florent Lheureux, Alessia Prestifilippo, Martin Delgado Maria Cruz, Rigal Romain, Massimo Antonelli, Torra Lluis Blanch, Franck Bonnetain, Maria Grazzia-Bocci, Jordi Mancebo, Emmanuel Samain, Hebert Paul, Gilles Capellier, Taissa Zavgorodniaia, Marion Soichot, Isabelle Malissin, Sebastian Voicu, Pierre Garçon, Antoine Goury, Lamia Kerdjana, Nicolas Deye, Emmanuel Bourgogne, Bruno Megarbane, Olfa Mejri, Marwa Ben Hmida, Salma Tannous, Lucie Chevillard, Laurence Labat, Patricia Risede, Hana Fredj, Maxime Léger, Marion Brunet, Gaël Le Roux, David Boels, Nicolas Lerolle, Souaad Farah, Hélène Amiel-Niemann, Nathalie Kubis, Xavier Declèves, Nicoals Peyraux, Frederic Baud, Micaela Serafini, Jean-Claude Alvarez, Annette Heinzelman, Mathieu Jozwiak, Sandrine Millasseau, Jean-Louis Teboul, Jean-Emmanuel Alphonsine, François Depret, Nathalie Richard, Pierre Attal, Christian Richard, Xavier Monnet, Denis Chemla, Salma Jerbi, Wafa Khedhiri, Hatem Necib, Paolo Scarfo, Charles Chevalier, Michael Piagnerelli, Alexandre Lafont, Antoine Galy, Claire Mancia, Amel Zerhouni, Kheira Tabeliouna, Ali Gaja, Bassem Hamrouni, Abir Malouch, Sami Fourati, Rihab Messaoud, Youssef Zarrouki, Amra Ziadi, Manal Rhezali, Zahira Zouizra, Drissi Boumzebra, Mohamed Abdennasser Samkaoui, Jennifer Brunet, Bertrand Canoville, Pierre Verrier, Calin Ivascau, Amélie Seguin, Xavier Valette, Damien Du Cheyron, Cedric Daubin, Wulfran Bougouin, Nadia Aissaoui, Lionel Lamhaut, Daniel Jost, Carole Maupain, Frankie Beganton, Adrien Bouglé, Florence Dumas, Eloi Marijon, Xavier Jouven, Alain Cariou, Florent Poirson, Ulriikka Chaput, Thomas Beeken, Leclerc Maxime, Oueslati Haikel, Dominique Vodovar, Jonathan Chelly, Philippe Marteau, Richard Chocron, Philippe Juvin, Thomas Loeb, Frederic Adnet, Eric Lecarpentier, Antoine Riviere, Bertand De Cagny, Thierry Soupison, Elodie Privat, Joséphine Escutnaire, Cyrielle Dumont, Valentine Baert, Christian Vilhelm, Hervé Hubert, Stéphane Leteurtre, Marion Fresco, Michael Bubenheim, Gaetan Beduneau, Dorothée Carpentier, Steven Grange, Elise Artaud-Macari, Benoit Misset, Fabienne Tamion, Christophe Girault, Guillaume Dumas, Sylvie Chevret, Virginie Lemiale, Djamel Mokart, Julien Mayaux, Frédéric Pène, Martine Nyunga, Pierre Perez, Anne-Sophie Moreau, Fabrice Bruneel, François Vincent, Kada Klouche, Jean Reignier, Antoine Rabbat, Elie Azoulay, Jean-Pierre Frat, Stéphanie Ragot, Jean-Michel Constantin, Gwenael Prat, Alain Mercat, Thierry Boulain, Alexandre Demoule, Jérôme Devaquet, Saad Nseir, Julien Charpentier, Laurent Argaud, Pascal Beuret, Jean-Damien Ricard, Christelle Teiten, Nicolas Marjanovic, Nicola Palamin, Erwan L'Her, Arthur Bailly, Julie Boisramé-Helms, Benoit Champigneulle, Toufik Kamel, Emmanuelle Mercier, Aurélie Le Thuaut, Jean-Baptiste Lascarrou, Amélie Rolle, Audrey De Jong, Gérald Chanques, Samir Jaber, Geoffroy Hariri, Jean-Luc Baudel, Vincent Dubée, Gabriel Preda, Simon Bourcier, Jeremie Joffre, Naïke Bigé, Hafid Ait-Oufella, Eric Maury, Houda Mater, Hamid Merdji, David Grimaldi, Christophe Rousseau, Jean-Paul Mira, Jean-Daniel Chiche, Ines Sedghiani, A Benabderrahim, Dhekra Hamdi, Asma Jendoubi, Mohamed Ali Cherif, Youssef Zied El Hechmi, Jerbi Zouheir, François Bagate, Radhwen Bousselmi, Frédérique Schortgen, Pierre Asfar, Emmanuel Guérot, Grelon Fabien, Nadia Anguel, Lasocki Sigismond, Henry-Lagarrigue Matthieu, Frédéric Gonzalez, Legay François, Christophe Guitton, Maleka Schenck, Doise Jean-Marc, Didier Dreyfuss, Peter Radermacher, Antoine Frère, Laurent Martin-Lefèvre, Gwenhaël Colin, Maud Fiancette, Matthieu Henry-Laguarrigue, Jean-Claude Lacherade, Christine Lebert, Isabelle Vinatier, Aihem Yehia, Aurélie Joret, Nicolas Menunier-Beillard, Dalila Benzekri-Lefevre, Arnaud Desachy, Fréderic Bellec, Gaëtan Plantefève, Jean-Pierre Quenot, Ferhat Meziani, Elsa Tavernier, Stephan Ehrmann, Nicolas Chudeau, Tommy Raveau, Valérie Moal, Pascal Houillier, Emmanuelle Rouve, Karim Lakhal, Charlotte Salmon Gandonnière, Youenn Jouan, Laetitia Bodet-Contentin, Adrien Balmier, Jonathan Messika, Etienne De Montmollin, Victorine Pouyet, Benjamin Sztrymf, Abirami Thiagarajah, Damien Roux, Marc Pineton De Chambrun, Charles-Edouard Luyt, François Beloncle, Nathalie Zapella, Stanislas Ledochowsky, Nicolas Terzi, Jean-Marc Mazou, Romain Sonneville, Sylvie Paulus, Yannick Fedun, Mickael Landais, Jean-Herlé Raphalen, Alain Combes, Zahir Amoura, Aemilia Jacquemin, Felipe Guerrero, Bertrand Marcheix, Nicolas Hernandez, Olivier Fourcade, Bernard Georges, Clément Delmas, Sarah Makoudi, Audrey Genton, Rémy Bernard, Guillaume Lebreton, Julien Amour, Charlotte Mazet, Fanny Bounes, Gurbuz Murat, Laure Cronier, Guillaume Robin, Caroline Biendel, Stein Silva, Samia Boubeche, Caroline Abriou, Véronique Wurtz, Vincent Scherrer, Nathalie Rey, Gioia Gastaldi, Benoit Veber, Fabien Doguet, Arnaud Gay, Bertrand Dureuil, Emmanuel Besnier, Antoine Rouget, Guillaume Gantois, Eric Magalhaes, Ruben Wanono, Roland Smonig, Mathilde Lermuzeaux, Jordane Lebut, Andremont Olivier, Claire Dupuis, Aguila Radjou, Bruno Mourvillier, Mathilde Neuville, Marie Pia D'ortho, Lila Bouadma, Anny Rouvel-Tallec, Marika Rudler, Nicolas Weiss, Vincent Perlbarg, Damien Galanaud, Dominique Thabut, Emna Rachdi, Ghada Mhamdi, Ahlem Trifi, Rim Abdelmalek, Sami Abdellatif, Foued Daly, Rochdi Nasri, Hanene Tiouiri, Salah Ben Lakhal, Geoffroy Rousseau, Romain Asmolov, Leslie Grammatico-Guillon, Adrien Auvet, Said Laribi, Denis Garot, Pierre François Dequin, Antoine Guillon, Jean-Louis Fergé, Gwénolé Abgrall, Ronan Hinault, Shazima Vally, Benoit Roze, Agathe Chaplain, Cyrille Chabartier, Anne-Charlotte Savidan, Sabia Marie, Andre Cabie, Dabor Resiere, Ruddy Valentino, Hossein Mehdaoui, Lucas Benarous, Marième Soda-Diop, Fouad Bouzana, Gilles Perrin, Jeremy Bourenne, Béatrice Eon, Dominique Lambert, Agnes Trebuchon, Géraldine Poncelet, Fleur Le Bourgeois, Levy Michael, Guillot Camille, Jérôme Naudin, Anna Deho, Stéphane Dauger, Michaël Sauthier, Krystale Bergeron-Gallant, Guillaume Emeriaud, Philippe Jouvet, Nicolas Tiebergien, Matthias Jacquet-Lagrèze, Jean-Luc Fellahi, Florent Baudin, Sandrine Essouri, Etienne Javouhey, Claude Guérin, Marie Lampin, Ouardia Mamouri, Patrick Devos, Yasemin Karaca-Altintas, Matthieu Vinchon, David Brossier, Redha Eltaani, Sonia Teyssedre, Meyet Sabine, Jean-Christophe Bouchut, Olivier Peguet, Lucie Petitdemange, Anne Sophie Guilbert, Nabil Tabet Aoul, Zakaria Addou, Nabil Aouffen, Benqqa Anas, Samira Kalouch, Khalid Yaqini, Aziz Chlilek, Rchi Abdou, Perrine Gravellier, Julie Chantreuil, Nadine Travers, Antoine Listrat, Claire Le Reun, Geraldine Favrais, Zoe Coppere, Stéphane Blanot, Juliette Montmayeur, Régis Bronchard, Stephane Rolando, Gilles Orliaguet, Pierre-Louis Leger, Jérôme Rambaud, Emilie Thueux, Alexandra De Larrard, Véronique Berthelot, Julien Denot, Marie Reymond, Alain Amblard, Sarah Morin-Zorman, Etienne Lengliné, Claire Pichereau, Eric Mariotte, Canet Emmanuel, Julien Poujade, Guillaume Trumpff, Ralf Janssen-Langenstein, Marie-Line Harlay, Noorah Zaid, Nawel Ait-Ammar, Christine Bonnal, Jean-Claude Merle, Francoise Botterel, Eric Levesque, Zakaria Riad, Mehdi Mezidi, Hodane Yonis, Mylène Aublanc, Sophie Perinel-Ragey, Floriane Lissonde, Aurore Louf-Durier, Romain Tapponnier, Bruno Louis, Jean-Marie Forel, Magali Bisbal, Samuel Lehingue, Romain Rambaud, Mélanie Adda, Sami Hraiech, Elisa Marchi, Antoine Roch, Vincent Guerin, Sacha Rozencwajg, Matthieu Schmidt, Guillaume Hekimian, Nicolas Bréchot, Jean Louis Trouillet, Sébastien Besset, Guillaume Franchineau, Ania Nieszkowska, Leprince Pascal, Maud Loiselle, Chemam Sarah, Dangers Laurence, Thomas Guillemette, Alice Jacquens, Sebastien Kerever, Bertrand Guidet, Philippe Aegerter, Vincent Das, Muriel Fartoukh, Jan Hayon, Mathieu Desmard, Jean-Pierre Fulgencio, Benjamin Zuber, A Soufi, K Khaleq, D Hamoudi, Charlotte Garret, Matthieu Peron, Emmanuel Coron, Cédric Bretonnière, Etienne Audureau, Winters Audrey, Duvoux Christophe, Jacquelinet Christian, Azoulay Daniel, Feray Cyrille, Wissal Aissaoui, Kawtar Rghioui, Wafae Haddad, Houcine Barrou, Anna Carteaux-Taeib, Renato Lupinacci, Gilles Manceau, Florence Jeune, Christophe Tresallet, Sahar Habacha, Ines Fathallah, Aymen Zoubli, Rafaa Aloui, Nadia Kouraichi, Emilie Jouet, Julie Badin, Brice Fermier, Marc Feller, Mathieu Serie, Jérôme Pillot, William Marie, Chloé Gisbert-Mora, Camille Vinclair, Pierre Lesbordes, Pascal Mathieu, Fabienne De Brabant, Emmanuel Muller, Marie-Aline Robaux, Mikhael Giabicani, Antoine Marchalot, Stéphanie Gelinotte, Pierre Louis Declercq, Jean-Pierre Eraldi, François Bougerol, Nicolas Meunier-Beillard, Hervé Devilliers, Jean-Philippe Rigaud, Camille Verrière, Fanny Ardisson, Nancy Kentish-Barnes, Gwenaëlle Jacq, Akli Chermak, Alexandre Lautrette, Matthieu Legrand, Alexis Soummer, Guillaume Thiery, Alice Cottereau, Emmanuel Canet, Marie Caujolle, Jérôme Allyn, Dorothée Valance, Caroline Brulliard, Olivier Martinet, Julien Jabot, Thomas Gallas, David Vandroux, Nicolas Allou, Arthur Durand, Rémi Nevière, Florian Delguste, Eric Boulanger, Sebastien Preau, Ruste Martin, Hélène Cochet, Jean Pierre Ponthus, Virginie Amilien, Martial Tchir, Elise Barsam, Mohsen Ayoub, Jean Francois Georger, Izaute Guillame, Julie Assaraf, Simona Tripon, Maxime Mallet, Guilaume Barbara, Guillaume Louis, Stéphane Gaudry, Nicolas Barbarot, Angéline Jamet, Hervé Outin, Sébastien Gibot, Pierre-Edouard Bollaert, Mathilde Holleville, Stéphane Legriel, Anne Laure Chateauneuf, Sébastien Cavelot, Jean-Denis Moyer, Jean Pierre Bedos, Philippe Merle, Aurelie Laine, De Sa Natalie, Mathieu Cornuault, Jérome Libot, Karim Asehnoune, Bertrand Rozec, Jacques Dantal, Michel Videcoq, Thècle Degroote, Emmanuelle Jaillette, Farid Zerimech, Balduyck Malika, Jean-François Llitjos, Marlène Amara, Guillaume Lacave, Béatrice Pangon, José Mavinga, Joseph Nsiala Makunza, M E Mafuta, Yves Yanga, Amisi Eric, Jp Ilunga, Ma Kilembe, Fanny Alby-Laurent, Julie Toubiana, Amel Mokline, Achraf Laajili, Helmi Amri, Imene Rahmani, Nidhal Mensi, Lazheri Gharsallah, Sofiene Tlaili, Bahija Gasri, Rym Hammouda, Amen Allah Messadi, Pierre-Antoine Allain, Nathallie Gault, Catherine Paugam-Burtz, Arnaud Foucrier, Bassem Chatbri, Yousra Bourbiaa, Lamia Thabet, Arthur Neuschwander, Looten Vincent, Jennifer Beck, Chhor Vibol, Yavchitz Amelie, Matthieu Resche-Rigon, Jean MantzRomain Pirracchio, Côme Bureau, Maxens Decavèle, Sébastien Campion, Roukia Ainsouya, Marie-Cécile Niérat, Hélène Prodanovic, Mathieu Raux, Thomas Similowski, Bruno-Pierre Dubé, Suela Demiri, Martin Dres, Faten May, Hervé Quintard, Ilias Kounis, Faouzi Saliba, Stephane André, Marc Boudon, Philippe Ichai, Aline Younes, Lionel Nakad, Audrey Coilly, Teresa Antonini, Rodolphe Sobesky, Eleonora De Martin, Didier Samuel, Noemie Hubert, Mai-Anh Nay, Johann Auchabie, Bruno Giraudeau, Reignier Jean, Michaël Darmon, Stephane Ruckly, Maïté Garrouste-Orgeas, Elisabeth Gratia, Dany Goldgran-Toledano, Samir Jamali, Anne Sylvie Dumenil, Carole Schwebel, Laurent Brisard, Philippe Bizouarn, Thierry Lepoivre, Johanna Nicolet, Jean Christophe Rigal, Jean Christian Roussel, Cherifa Cheurfa, Julien Abily, Thomas Lescot, Isaline Page, Stéphanie Warnier, Monique Nys, Anne-Françoise Rousseau, Pierre Damas, Fabrice Uhel, Mathieu Lesouhaitier, Murielle Grégoire, Baptiste Gaudriot, Arnaud Gacouin, Yves Le Tulzo, Erwan Flecher, Karin Tarte, Jean-Marc Tadié, Quentin Georges, M Soares, Kyeongman Jeon, Sandra Oeyen, Chin Kook Rhee, Pascale Gruber, Marlies Ostermann, Quentin Hill, Peter Depuydt, Christelle Ferra, Alice Muller, Bourmaud Aurelie, Christopher Niles, Fabien Herbert, Sylviane Pied, Séverine Loridant, Nadine François, Anne Bignon, Boualem Sendid, Caroline Lemaitre, Celine Dupre, Aymen Zayene, Lucie Portier, Nathalie De Freitas Caires, Philippe Lassalle, Aymeric Le Neindre, Pascal Selot, Daniel Ferreiro, Maria Bonarek, Stépahen Henriot, Julie Rodriguez, Mara Taddei, Mauro Di Bari, Cheryl Hickmann, Diego Castanares-Zapatero, Louise Deldicque, Peter Van Den Bergh, Gilles Caty, Jean Roeseler, Marc Francaux, Pierre-François Laterre, Bastien Dupuis, Sharam Machayeckhi, Celine Sarfati, Alex Moore, Paula Mendialdua, Emilie Rodet, Catherine Pilorge, Francois Stephan, Saida Rezaiguia-Delclaux, Jonathan Dugernier, Michel Hesse, Thibaud Jumetz, Emilie Bialais, Virginie Depoortere, Jean Bernard Michotte, Xavier Wittebole, François Jamar
No abstract text is available yet for this article.
January 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28073792/adult-parenteral-nutrition-in-the-north-of-england-a-region-wide-audit
#10
Jessica K Dyson, Nick Thompson
OBJECTIVES: Parenteral nutrition (PN) is widely used to provide nutritional support to patients with inaccessible or inadequate length of gut or non-functioning gut. The objective was to compare practice in PN administration to results of the National Confidential Enquiry into Patient Outcome and Death (NCEPOD) report, 'A Mixed Bag', and to establish whether good practice was being followed within this part of the UK. SETTING: Using the Northern Nutrition Network (NNN), we examined the care of adult patients receiving PN in all 10 secondary care hospitals in our region...
January 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28072933/altered-blood-levels-of-vitamin-d-cathelicidin-and-parathyroid-hormone-in-patients-with-sepsis-a-pilot-study
#11
T Greulich, W Regner, M Branscheidt, C Herr, A R Koczulla, C F Vogelmeier, R Bals
It has been recognised that vitamin D (VitD) has a potential role in the regulation of inflammation and protection from infection. In a prospective clinical observational pilot study, we investigated the serum levels of 25-hydroxyvitamin-D3 (25(OH)D3), 1,25-hydroxyvitamin-D3 (1,25(OH)2D3), parathyroid hormone (PTH), and cathelicidin in intensive care unit (ICU) patients with or without systemic inflammatory response syndrome (SIRS). We included 32 patients with SIRS (septic patients), 16 ICU patients without SIRS, and 16 healthy controls...
January 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/28072671/evaluation-of-the-association-of-early-elevated-lactate-with-outcomes-in-children-with-severe-sepsis-or-septic-shock
#12
Noelle Gorgis, Jeannette M Asselin, Cynthia Fontana, R Scott Heidersbach, Heidi R Flori, Shan L Ward
OBJECTIVE: The aim of the study was to assess the association of initial lactate (L0) with mortality in children with severe sepsis. METHODS: This prospective cohort study included 74 patients younger than 18 years with severe sepsis admitted to the pediatric intensive care unit (PICU) of a tertiary, academic children's hospital with lactate measured within 3 hours of meeting severe sepsis or septic shock. The primary outcome was in-hospital mortality. The secondary outcomes included PICU and hospital length of stay...
January 9, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28069912/idiosyncratic-drug-induced-neutropenia-agranulocytosis
#13
Emmanuel Andrès, Rachel Mourot-Cottet, Frédéric Maloisel, François Séverac, Olivier Keller, Thomas Vogel, Martine Tebacher, Jean-Christophe Weber, Georges Kaltenbach, Jacques-Eric Gottenberg, Bernard Goichot, Jean Sibilia, Anne-Sophie Korganow, Raoul Herbrecht
BACKGROUD: Few data is currently available on neutropenia and agranulocytosis related to drug intake. We report here data on 203 patients with established idiosyncratic drug-induced agranulocytosis, followed up in a referral centre within a university hospital. PATIENTS AND METHODS: Data from 203 patients with idiosyncratic drug-induced agranulocytosis were retrospectively reviewed. All cases were extracted from a cohort study on agranulocytosis in the Strasbourg University Hospital (Strasbourg, France) RESULTS: : The mean age was 61...
January 9, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28069319/effect-of-ulinastatin-combined-with-thymosin-alpha1-on-sepsis-a-systematic-review-and-meta-analysis-of-chinese-and-indian-patients
#14
REVIEW
Dadong Liu, Zongying Yu, Jiangtao Yin, Yikun Chen, Hao Zhang, Fan Xin, Haiyan Fu, Bing Wan
PURPOSE: To assess the effects of urinary trypsin inhibitor (UTI) ulinastatin combined with thymosin alpha1 (Tα1) on sepsis. MATERIALS AND METHODS: The meta-analysis included 8 randomized controlled trials (N=1112 patients) on UTI-based therapy for sepsis published before July 10, 2016. Two investigators independently extracted data and assessed the quality of each study. The short-term mortality rate, duration of mechanical ventilator and vasopressor use, length of intensive care unit stay, Acute Physiology and Chronic Health Evaluation (APACHE) II score, and differences in inflammatory cytokines (interleukin [IL]-6, IL-10, and tumor necrosis factor α) were assessed using statistical software...
December 27, 2016: Journal of Critical Care
https://www.readbyqxmd.com/read/28068970/quadriplegia-caused-by-an-epidural-abscess-occurring-at-the-same-level-of-cervical-destructive-spondyloarthropathy-a-case-report
#15
Jun-Seok Lee, Ji-Hyun Ryu, Jong-Tae Park, Ki-Won Kim
BACKGROUND: Destructive spondyloarthropathy (DSA) is one of the major complications in patients undergoing long-term hemodialysis. To the best of our knowledge, an epidural abscess occurring at the level of preexisting cervical DSA has not been well described in the literature. We report a unique case of quadriplegia caused by an epidural abscess occurring at the same level of preexisting cervical DSA. CASE PRESENTATION: A 49-year-old woman was transferred to our emergency department with 5 days of sepsis, drowsy mental status, and quadriplegia below the C5 level...
January 10, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28068437/association-between-early-lactate-levels-and-30-day-mortality-in-clinically-suspected-sepsis-in-children
#16
Halden F Scott, Lina Brou, Sara J Deakyne, Allison Kempe, Diane L Fairclough, Lalit Bajaj
Importance: Improving emergency care of pediatric sepsis is a public health priority, but optimal early diagnostic approaches are unclear. Measurement of lactate levels is associated with improved outcomes in adult septic shock, but pediatric guidelines do not endorse its use, in part because the association between early lactate levels and mortality is unknown in pediatric sepsis. Objective: To determine whether the initial serum lactate level is associated with 30-day mortality in children with suspected sepsis...
January 9, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28067713/widespread-down-regulation-of-cardiac-mitochondrial-and-sarcomeric-genes-in-patients-with-sepsis
#17
Scot J Matkovich, Belal Al Khiami, Igor R Efimov, Sarah Evans, Justin Vader, Ashwin Jain, Bernard H Brownstein, Richard S Hotchkiss, Douglas L Mann
OBJECTIVES: The mechanism(s) for septic cardiomyopathy in humans is not known. To address this, we measured messenger RNA alterations in hearts from patients who died from systemic sepsis, in comparison to changed messenger RNA expression in nonfailing and failing human hearts. DESIGN: Identification of genes with altered abundance in septic cardiomyopathy, ischemic heart disease, or dilated cardiomyopathy, in comparison to nonfailing hearts. SETTING: ICUs at Barnes-Jewish Hospital, St...
January 6, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28065955/analysis-of-pattern-of-mortality-in-medicine-and-allied-departments-at-a-tertiary-care-hospital-in-islamabad-a-losing-battle-against-sepsis
#18
Saad Azim, Sidra Zahoor, Jamal Janjua, Azer Majeed, Syed Waqar Hussain
OBJECTIVE: To identify the pattern of mortality in medical wards of a tertiary care hospital. METHODS: This retrospective study was conducted at the Khan Research Laboratories Hospital, Islamabad, Pakistan, and comprised medical records of people who died during hospital stay between December 2013 and November 2014.SPSS 11 was used for data analysis. RESULTS: Of the 3,228 admissions, 105(3.25%) patients expired. Of them, 41(39.04%) were men with a mean age of 55±13...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28062972/predictive-performance-of-the-quick-sequential-organ-failure-assessment-score-as-a-screening-tool-for-sepsis-mortality-and-intensive-care-unit-admission-in-patients-with-febrile-neutropenia
#19
Minsoo Kim, Shin Ahn, Won Young Kim, Chang Hwan Sohn, Dong Woo Seo, Yoon-Seon Lee, Kyung Soo Lim
PURPOSE: In Sepsis-3, the quick Sequential Organ Failure Assessment (qSOFA) score was developed as criteria to use for recognizing patients who may have poor outcomes. This study was performed to evaluate the predictive performance of the qSOFA score as a screening tool for sepsis, mortality, and intensive care unit (ICU) admission in patients with febrile neutropenia (FN). We also tried to compare its performance with that of the systemic inflammatory response syndrome (SIRS) criteria and Multinational Association of Supportive Care in Cancer (MASCC) score for FN...
January 6, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28062114/effect-of-immediate-administration-of-antibiotics-in-patients-with-sepsis-in-tertiary-care-a-systematic-review-and-meta-analysis
#20
REVIEW
Amy N B Johnston, Joon Park, Suhail A Doi, Vicki Sharman, Justin Clark, Jemma Robinson, Julia Crilly
PURPOSE: The goal of this review was to synthesize existing evidence regarding outcomes (mortality) for patients who present to the emergency department, are administered antibiotics immediately (within 1 hour) or later (>1 hour), and are diagnosed with sepsis. METHODS: A search of PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and CINAHL, using the MeSH descriptors "sepsis," "systemic inflammatory response syndrome," "mortality," "emergency," and "antibiotics," was performed to identify studies reporting time to antibiotic administration and mortality outcome in patients with sepsis...
January 3, 2017: Clinical Therapeutics
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