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https://www.readbyqxmd.com/read/28436607/visual-complaints-in-intracranial-germinomas
#1
Didier Frappaz, Claire Pedone, Philippe Thiesse, Alexandru Szathmari, Cécile Faure Conter, Carmine Mottolese, Christian Carrie
OBJECTIVE: Patients with brain tumors often report having visual complaints. This may be due to increased intracranial pressure, compression/invasion of the optic pathway or diplopia. We assessed the incidence and the etiology of visual symptoms in patients with intracranial germinoma tumors (ICGTs). METHODS AND MATERIALS: We performed a blinded retrospective review of the clinical charts and the initial magnetic resonance imaging (MRI) of 28 patients with ICGT...
April 24, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28436149/transgenic-mir156-switchgrass-in-the-field-growth-recalcitrance-and-rust-susceptibility
#2
Holly L Baxter, Mitra Mazarei, Alexandru Dumitrache, Jace Natzke, Miguel Rodriguez, Jiqing Gou, Chunxiang Fu, Robert W Sykes, Geoffrey B Turner, Mark F Davis, Steven Brown, Brian Davison, Zeng-Yu Wang, C Neal Stewart
Sustainable utilization of lignocellulosic perennial grass feedstocks will be enabled by high biomass production and optimized cell wall chemistry for efficient conversion into biofuels. MicroRNAs are regulatory elements that modulate the expression of genes involved in various biological functions in plants, including growth and development. In greenhouse studies, overexpressing a microRNA (miR156) gene in switchgrass had dramatic effects on plant architecture and flowering, which appeared to be driven by transgene expression levels...
April 24, 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/28429014/formation-of-mono-and-binuclear-neodymium-iii-gluconate-complexes-in-aqueous-solutions-in-the-ph-range-of-2-8
#3
Bence Kutus, Norbert Varga, Gábor Peintler, Alexandru Lupan, Amr A A Attia, István Pálinkó, Pál Sipos
The complex formation between Nd(iii) and d-gluconate (Gluc(-)) is of relevance in modelling the chemical equilibria of radioactive waste repositories. In the present work, the formation of NdpGlucqH-r complexes at 25 °C and pH = 2-8 was studied via spectrophotometry, potentiometry, freezing point depression, conductometry and NMR spectroscopy. In addition to the four mononuclear complexes (pq-r = 110, 120, 130 and 11-2), the formation of two binuclear, so far unknown complexes (pq-r = 23-2 and 24-2) was revealed...
April 21, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28425621/p53-competent-cells-and-p53-deficient-cells-display-different-susceptibility-to-oxygen-functionalized-graphene-cytotoxicity-and-genotoxicity
#4
Dayton M Petibone, Thikra Mustafa, Shawn E Bourdo, Andersen Lafont, Wei Ding, Alokita Karmakar, Zeid A Nima, Fumiya Watanabe, Daniel Casciano, Suzanne M Morris, Vasily N Dobrovolsky, Alexandru S Biris
Due to the distinctive physical, electrical, and chemical properties of graphene nanomaterials, numerous efforts pursuing graphene-based biomedical and industrial applications are underway. Oxidation of pristine graphene surfaces mitigates its otherwise hydrophobic characteristic thereby improving its biocompatibility and functionality. Yet, the potential widespread use of oxidized graphene derivatives raises concern about adverse impacts on human health. The p53 tumor suppressor protein maintains cellular and genetic stability after toxic exposures...
April 20, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/28424554/arterial-stiffness-in-hematologic-malignancies
#5
REVIEW
Ioana Mozos, Georgiana Borzak, Alexandru Caraba, Rodica Mihaescu
Malignant and cardiovascular disorders are the top causes of mortality worldwide. This article reviews the main literature data and mechanisms linking hematologic malignancies and arterial stiffness, focusing on recent experimental and clinical results. Several links were found in hematologic malignancies between complete blood count and arterial stiffness. Chemotherapy, especially anthracyclines, cyclophosphamide and tyrosine kinase inhibitors, as well as radiotherapy and hematopoietic stem cell transplantation are the main known causes of arterial stiffness increase in hematologic malignancies...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28424206/extending-the-fossil-record-of-polytrichaceae-early-cretaceous-meantoinea-alophosioides-gen-et-sp-nov-permineralized-gametophytes-with-gemma-cups-from-vancouver-island
#6
Alexander C Bippus, Ruth A Stockey, Gar W Rothwell, Alexandru M F Tomescu
PREMISE OF THE STUDY: Diverse in modern ecosystems, mosses are dramatically underrepresented in the fossil record. Furthermore, most pre-Cenozoic mosses are known only from compression fossils, lacking detailed anatomical information. When preserved, anatomy vastly improves resolution in the systematic placement of fossils. Lower Cretaceous deposits at Apple Bay (Vancouver Island, British Columbia, Canada) contain a diverse anatomically preserved flora that includes numerous bryophytes, many of which have yet to be characterized...
April 19, 2017: American Journal of Botany
https://www.readbyqxmd.com/read/28422663/a-neural-probe-with-up-to-966-electrodes-and-up-to-384-configurable-channels-in-0-13-%C3%AE-m-soi-cmos
#7
Carolina Mora Lopez, Jan Putzeys, Bogdan Cristian Raducanu, Marco Ballini, Shiwei Wang, Alexandru Andrei, Veronique Rochus, Roeland Vandebriel, Simone Severi, Chris Van Hoof, Silke Musa, Nick Van Helleputte, Refet Firat Yazicioglu, Srinjoy Mitra
In vivo recording of neural action-potential and local-field-potential signals requires the use of high-resolution penetrating probes. Several international initiatives to better understand the brain are driving technology efforts towards maximizing the number of recording sites while minimizing the neural probe dimensions. We designed and fabricated (0.13- μm SOI Al CMOS) a 384-channel configurable neural probe for large-scale in vivo recording of neural signals. Up to 966 selectable active electrodes were integrated along an implantable shank (70 μm wide, 10 mm long, 20  μm thick), achieving a crosstalk of [Formula: see text] dB...
April 14, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28417912/electrospun-fiber-pads-of-cellulose-acetate-and-essential-oils-with-antimicrobial-activity
#8
Ioannis L Liakos, Alina Maria Holban, Riccardo Carzino, Simone Lauciello, Alexandru Mihai Grumezescu
The method of electrospinning was used to create nanofibers made of cellulose acetate (CA) and essential oils (EOs). CA polymer at 15% w/v was dissolved in acetone and then 1% or 5% v/v of EOs was added to the polymer solution. The utilized essential oils were rosemary and oregano oils. Then, the CA/EOs in acetone solution were electrospun, creating micro/nanofibers, approximately 700-1500 nm in diameter. Raman spectroscopy was used to detect the attachment of the EOs in the CA electrospun fibers (ESFs). Scanning electron microscopy was used to study the morphology, topography and dimensions of the ESFs...
April 12, 2017: Nanomaterials
https://www.readbyqxmd.com/read/28417068/photoacoustic-in-vitro-flow-cytometry-for-nanomaterial-research
#9
Dmitry A Nedosekin, Tariq Fahmi, Zeid A Nima, Jacqueline Nolan, Chengzhong Cai, Mustafa Sarimollaoglu, Enkeleda Dervishi, Alexei Basnakian, Alexandru S Biris, Vladimir P Zharov
Conventional flow cytometry is a versatile tool for drug research and cell characterization. However, it is poorly suited for quantification of non-fluorescent proteins and artificial nanomaterials without the use of additional labeling. The rapid growth of biomedical applications for small non-fluorescent nanoparticles (NPs) for drug delivery and contrast and therapy enhancement, as well as research focused on natural cell pigments and chromophores, demands high-throughput quantification methods for the non-fluorescent components...
June 2017: Photoacoustics
https://www.readbyqxmd.com/read/28414596/anesthesia-case-of-the-month
#10
Alexandru C Tutunaru, Richard Chernevsky, Valts Ozolins, Charlotte Sandersen, Ilmars Duritis
No abstract text is available yet for this article.
May 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28413549/challenges-in-a-case-of-ophthalmic-artery-aneurysm-associated-with-abnormal-internal-carotid-arteries
#11
Eduard B Dinca, Felix Brehar, Andrei Giovani, Alexandru V Ciurea
Ophthalmic artery aneurysms account for 5% of all cerebral aneurysms and are an important cause of morbidity and mortality related to subarachnoid hemorrhage. The diagnosis is often made only when the aneurysm is large enough to become symptomatic. They remain technically challenging for both neurosurgeon and interventional radiologist. We present the case of a 62-year-old woman admitted for transient loss of consciousness, followed by generalized tonic-clonic seizures. Computed tomography (CT) showed a subarachnoid hemorrhage (SAH), clinically graded as Hunt and Hess III...
January 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28413048/milk-c-reactive-protein-in-canine-mastitis
#12
Iosif Vasiu, Roman Dąbrowski, Silvia Martinez-Subiela, Jose J Ceron, Anna Wdowiak, Raul Alexandru Pop, Florinel Gheorghe Brudaşcă, Josep Pastor, Asta Tvarijonaviciute
Presence of mastitis in lactating bitches can become life threatening for both the bitch and pups. The aim of the present study was to evaluate a possible utility of C-reactive protein (CRP) in both milk and serum for canine mastitis diagnosis. Our study showed that milk CRP levels ranged between 0.1 and 4.9μg/mL and from 0.3 to 40.0μg/mL in healthy and diseased bitches (P<0.01), respectively, while serum CRP levels ranged between 2.0 and 8.6μg/mL and between 0.3 and 162.3μg/mL in healthy and diseased bitches (P<0...
April 2017: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/28388265/phenotyping-before-starting-treatment-in-copd
#13
Nikolaos Siafakas, Alexandru Corlateanu, Evangelia Fouka
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous and complex disease with great morbidity and mortality. Despite the new developments in the managements of COPD, it was recognized that not all patients benefit from the available medications. Therefore, efforts to identify subgroups or phenotypes had been made in order to predict who will respond to a class of drugs for COPD. This review will discuss phenotypes, endotypes, and subgroups such as the frequent exacerbator, the one with systemic inflammation, the fast decliner, ACOS, and the one with co-morbidities and their impact on therapy...
April 7, 2017: COPD
https://www.readbyqxmd.com/read/28386870/two-release-rates-from-monolithic-carboxymethyl-starch-tablets-formulation-characterization-and-in-vitro-in-vivo-evaluation
#14
Tien Canh Le, Mircea Alexandru Mateescu
Most of non-steroidal anti-inflammatory drugs (NSAIDs) including ibuprofen at more than 1200 mg/day may generate gastrointestinal and cardiovascular side effects. Bilayer or multiparticulate devices have been developed for controlled release in order to prevent undesired side effects. A new "two release rate (2RR) monolithic tablets" approach is now proposed for controlled release of poorly soluble drugs, particularly NSAIDs. Ibuprofen was used as model drug. This concept is based on a calcium carboxymethyl-starch (CaCMS) complex as a novel, low-cost excipient for monolithic dosage forms easy to manufacture by direct compaction...
April 6, 2017: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/28381375/superior-mesenteric-artery-first-approach-versus-standard-pancreaticoduodenectomy-a-systematic-review-and-meta-analysis
#15
Ionut Negoi, Sorin Hostiuc, Alexandru Runcanu, Ruxandra Irina Negoi, Mircea Beuran
BACKGROUND: The superior mesenteric artery (SMA) first approach was proposed recently as a new modification of the standard pancreaticoduodenectomy. Increasing evidence showed that a periadventiceal dissection of the SMA with early transection of the inflow during pancreaticoduodenectomy associates better early perioperative results, and setup the scene for long-term oncological benefits. The objectives of the current study are to compare the operative results and long-term oncological outcomes of SMA first approach pancreaticoduodenectomy (SMA-PD) with standard pancreaticoduodenectomy (S-PD)...
April 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28377109/zuckerkandl-s-tubercle-and-its-relationship-to-the-recurrent-laryngeal-nerve-a-cadaveric-dissection-and-meta-analysis
#16
Brandon Michael Henry, Beatrice Sanna, Jens Vikse, Matthew J Graves, Alexandru Spulber, Cecylia Witkowski, Iwona M Tomaszewska, R Shane Tubbs, Krzysztof A Tomaszewski
OBJECTIVE: Zuckerkandl's tubercle (ZT), when present, is an anatomical landmark by which surrounding structures such as the recurrent laryngeal nerve (RLN) can be identified intraoperatively. This study aimed to investigate the prevalence and anatomical characteristics of Zuckerkandl's tubercle by combining cadaveric dissection with a meta-analysis. METHODS: Through October 2016, an extensive search of PubMed, CNKI, ScienceDirect, EMBASE, BIOSIS, SciELO, and Web of Science was completed...
April 1, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28371905/the-quest-for-equilibrium-exploring-the-thin-red-line-between-bleeding-and-ischaemic-risks-in-the-management-of-acute-coronary-syndromes-in-chronic-kidney-disease-patients
#17
Alexandru Burlacu, Simonetta Genovesi, Alberto Ortiz, Mehmet Kanbay, Patrick Rossignol, Maciej Banach, Jolanta Malyszko, David Goldsmith, Adrian Covic
Coronary artery disease and acute coronary syndrome (ACS) are both common in patients with chronic kidney disease (CKD). CKD patients have higher risks of bleeding and thrombosis. However, they remain under-represented in major randomized clinical trials (RCTs), and there is no medical evidence-based foundation on which to issue specific recommendations about the management of ACS in CKD. CKD patients with ACS frequently are diagnosed later, receive fewer acute interventions and are at increased risk of over-dosage of medications and under-prescription/under-performance of interventional treatments than CKD patients without ACS...
March 27, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28371635/axillary-skin-metastasis-of-renal-cell-carcinoma-case-report
#18
Cristinel D Badiu, Alexandru Aungurenci, Cristina A Manea, Radu Tomosoiu, Narcis Chirca, Gabriela Rahnea-Nita, Liliana Andronache, Valentin T Grigorean, Victor L Madan
INTRODUCTION: Metastatic diseases are seen in approximately 25% of all cases with renal cell carcinoma and sometimes they can appear in unusual sites. CASE PRESENTATION: We present a 35-year old patient with a painful left axillary mass which causes the functional impairment of the left arm. The axillary mass appeared 2 years after the nephrectomy performed for a left renal cell carcinoma. Numerous metastases have been identified through CT scans during the postoperative evolution of the disease for which the patient underwent adjuvant therapy with tyrosine-kinase inhibitors...
March 18, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28366043/nurses-perceptions-of-weight-gain-and-obesity-in-the-prison-environment
#19
Khurshid Choudhry, David Armstrong, Alexandru Dregan
This study aimed to improve understanding of obesity in prison by investigating prison nurses' perceptions of weight gain and obesity. In-depth semistructured interviews were carried out with 17 nurses who worked in two male prisons in the United Kingdom. Nurses identified a variety of factors that they believed contributed to obesity and weight gain in the prison setting. These included factors caused by prisoner behavior, such as poor food choices and sedentary lifestyle. Factors influenced by the prison environment, such as stress of imprisonment, prison regime, and prison culture, were also seen as significant...
January 1, 2017: Journal of Correctional Health Care
https://www.readbyqxmd.com/read/28365757/developmental-programmes-in-the-evolution-of-equisetum-reproductive-morphology-a-hierarchical-modularity-hypothesis
#20
Alexandru M F Tomescu, Ignacio H Escapa, Gar W Rothwell, Andrés Elgorriaga, N Rubén Cúneo
Background: The origin of the Equisetum strobilus has long been debated and the fossil record has played an important role in these discussions. The paradigm underlying these debates has been the perspective of the shoot as node-internode alternation, with sporangiophores attached at nodes. However, fossils historically excluded from these discussions (e.g. Cruciaetheca and Peltotheca ) exhibit reproductive morphologies that suggest attachment of sporangiophores along internodes, challenging traditional views...
March 1, 2017: Annals of Botany
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