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acute hemorrhagic edema of infancy

E F Johnson, D A Wetter, J S Lehman, J L Hand, D M R Davis, M M Tollefson
BACKGROUND: Leukocytoclastic vasculitis (LCV) in children is a complex group of conditions. OBJECTIVES: This study presents the demographics, clinical features, direct immunofluorescence (DIF) results and suspected aetiologies of 56 biopsy-confirmed cases of leukocytoclastic vasculitis in children. METHODS: Retrospective review of 56 children seen at Mayo Clinic in Rochester, Minnesota, from 1993 to 2013 with clinical features and cutaneous biopsy consistent with LCV...
August 31, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
Maria Ceci, Margherita Conrieri, Irene Raffaldi, Veronica Pagliardini, Antonio Francesco Urbino
We report a case of acute hemorrhagic edema of infancy (AHEI) occurred in an 11-month-old male infant after upper respiratory tract infection. The onset was dramatic with petechiae, ecchymosis, and annular, nummular, or targetoid purpuric plaques on the extremities, face, and ears. Acute hemorrhagic edema of infancy is a benign form of leukocytoclastic vasculitis that typically affects children between 4 and 24 months of age. The etiology remains still unknown. The potential triggers of AHEI include preceding bacterial or viral infections, immunizations, and drugs...
May 30, 2016: Pediatric Emergency Care
C Serra E Moura Garcia, A Sokolova, M L Torre, C Amaro
Acute Hemorrhagic Edema of Infancy is a small vessel leucocytoclastic vasculitis affecting young infants. It is characterized by large, target-like, macular to purpuric plaques predominantly affecting the face, ear lobes and extremities. Non-pitting edema of the distal extremities and low-grade fever may also be present. Extra-cutaneous involvement is very rare. Although the lesions have a dramatic onset in a twenty-four to forty-eight hour period, usually the child has a non-toxic appearance. In most cases there are no changes in laboratory parameters...
January 2016: European Annals of Allergy and Clinical Immunology
James L Homme, Jason M Block
Acute hemorrhagic edema of infancy (AHEI) is a rare acute benign cutaneous leukocytoclastic vasculitis affecting children younger than 24 months of age. Its presentation can be confused with those of urticaria, erythema multiforme, Henoch-Schönlein purpura, idiopathic thrombocytopenia,meningococcemia, Kawasaki disease, and drug rash. We present 2 cases of acute hemorrhagic edema of infancy, discuss the characteristics of AHEI, and compare and contrast AHEI with similar dermatologic presentations. This review provides emergency physicians with the basic knowledge necessary to easily recognize AHEI as a distinct clinical entity...
May 2016: American Journal of Emergency Medicine
Kameshwar Prasad Roy, Bhushan Madke, Sumit Kar, Nidhi Yadav
No abstract text is available yet for this article.
November 2015: Indian Journal of Dermatology
Diego Fontana Siqueira Cunha, Ana Letícia Fornazieri Darcie, Gabriel Nuncio Benevides, Angela Espósito Ferronato, Noely Hein, Denise Swei Lo, Cristina Ryoka Miyao Yoshioka, Maki Hirose, Debora Morais Cardoso, Alfredo Elias Gilio
Acute Hemorrhagic Edema of Infancy (AHEI) is a rare leukocytoclastic vasculitis, clinically characterized by the classical triad: palpable purpuric skin lesions, edema and fever, and is commonly misdiagnosed as Henoch-Schönlein purpura. In addition to its sudden onset, AHEI is also characterized by its self-limited course with complete and spontaneous recovery occurring between 1 and 3 weeks. Because of the scarcity of studies on therapy with corticosteroids, the conservative approach is usually recommended...
July 2015: Autopsy & case reports
Luciana Breda, Simone Franchini, Valentina Marzetti, Francesco Chiarelli
Acute hemorrhagic edema of infancy (AHEI) is a benign leukocytoclastic small-vessel vasculitis that affects infants, presenting with a classic clinical triad. Because of the self-limited progression, conservative management is the most common approach. We describe a case of AHEI apparently triggered by an Escherichia coli urinary tract infection.
November 2015: Pediatric Dermatology
Yousef Binamer
Acute hemorrhagic edema of infancy (AHEI) is a rare type of leuckocytoclastic vasculitis. It affects mainly children less than two years of age. Many precipitating factors have been reported, including infectious etiology and vaccination. We are reporting a two-year-old boy with AHEI after measles, mumps, and rubella (MMR) vaccine. To our knowledge this is the second reported case after an MMR vaccine.
May 2015: Annals of Saudi Medicine
Joana A Oliveira, Leonor Lopes, Ana Fraga, Luís Soares-de-Almeida, Bárbara Águas, António Siborro-Azevedo
No abstract text is available yet for this article.
February 2015: Journal of Pediatrics
Ganesh Avhad, Priyanka Ghuge, Hemangi Jerajani
No abstract text is available yet for this article.
July 2014: Indian Dermatology Online Journal
Abhijit Dutta, Sudip Kumar Ghosh
No abstract text is available yet for this article.
August 2014: Indian Pediatrics
Maria Cristina Maggio, Fabrizia Ferraro, Saveria Sabrina Ragusa, Umberto Corpora, Giovanni Corsello
Acute hemorrhagic edema of infancy (AHEI) was considered a rare form of Henoch-Schönlein purpura; however, it is now regarded as an independent disease typically involving patients aged 4-24 months. The authors describe the clinical case of a toddler aged 8 months, with skin erythematous pomphoid lesions, treated at home with topical steroids without benefits. The appearance of new lesions and the worsening of the previous skin signs induced the parents to drive the child to the hospital. The medical history revealed the administration of a vaccine dose 2 months before...
May 2014: Case Reports in Dermatology
Miri Dotan, Elhanan Nahum, Daniel Weigl, Efraim Bilavsky
UNLABELLED: Acute hemorrhagic edema of infancy (AHEI) is a benign, self-limiting vasculitis that usually resolves completely without any sequelae or a need for active therapy. To our knowledge, compartment syndrome because of AHEI has not been reported. Chart data for a single case were reviewed and reported in a retrospective study. A 19-month-old male presented with petechial rash and swelling of the left lower leg. AHEI was diagnosed clinically and confirmed by skin biopsy. On the basis of the clinical appearance, compartment syndrome of the foot was suspected...
September 2014: Journal of Pediatric Orthopedics. Part B
Jeyanthini Risikesan, Uffe Koppelhus, Torben Steiniche, Mette Deleuran, Troels Herlin
We present a case of an 18-month-old boy who showed severe clinical signs indicative of acute hemorrhagic edema of infancy (AHEI) with painful purpuric skin affection primarily of the face and marked edema of the ears. The histological findings were diagnostic for leukocytoclastic vasculitis and thus met the histological criteria for AHEI. Indicative of infection as causative agent for the condition were symptoms of gastroenteritis. High-dose intravenous corticosteroids led to a fast resolution of symptoms and normalization of laboratory parameters...
2014: Case Reports in Dermatological Medicine
Jennifer A Glamann, Andrea K Morrison, Kerry P Mychaliska
No abstract text is available yet for this article.
March 2014: Hospital Pediatrics
Anubhav N Mathur, Erin F Mathes
Acute urticaria is a self-limited cutaneous condition marked by transient, erythematous, and pruritic wheals. It is a hypersensitivity response that is often secondary to infection, medications, or food allergies in children. In contrast, the urticarial "mimickers" described in this review article are often seen in the context of fever and extracutaneous manifestations in pediatric patients. The differential diagnosis ranges from benign and self-limited hypersensitivity responses to multisystem inflammatory diseases...
November 2013: Dermatologic Therapy
Satyabrata Roy Chowdhoury, Samrat Ganguly, Satarupa Mukherjee, Moumita Samanta, Kalpana Datta
The authors report an 11-mo-old child presenting with acute onset appearance of large, erythematous, palpable purpuric lesions involving face, extremities and trunk. Skin biopsy from the margin of the lesions showed leukocytoclastic vasculitis suggesting a diagnosis of acute hemorrhagic edema of infancy. This rare type of cutaneous vasculitis, despite its grave presentation is a benign condition with self-limiting course.
August 2014: Indian Journal of Pediatrics
Ahmed H Alhammadi, Ashraf Adel, Mohamed A Hendaus
Acute hemorrhagic edema of infancy (AHEI) is a benign type of leukocytoclastic vasculitis. It is a benign phenomenon although it manifests with fever, large palpable purpuric skin lesions, and edema. The presentation of AHEI can often resemble that of Henoch-Schönlein purpura. Since AHEI is a self-limited disease, conservative management is the most commonly followed approach. Our patient had complete resolution of AHIE without medical treatment.
2013: Clinical, Cosmetic and Investigational Dermatology
Saurabh R Jindal, Mahendra M Kura
A patient presenting with fever and purpura often presents a diagnostic challenge for the dermatologist. Acute hemorrhagic edema of infancy (AHEI) is a rare acute cutaneous leukocytoclastic vasculitic syndrome of infants leading to this presentation. We present an 18-month-old girl with AHEI who presented with fever, edema, and purpuric lesions involving the face, ears and extremities with uneventful complete recovery.
April 2013: Indian Dermatology Online Journal
Cristiana Carvalho, Gustavo Januário, Paulo Maia
No abstract text is available yet for this article.
2013: BMJ Case Reports
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