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https://www.readbyqxmd.com/read/28544438/genome-wide-identification-characterization-and-evolution-of-cuticular-protein-genes-in-the-malaria-vector-anopheles-sinensis-diptera-culicidae
#1
Bai-Qi Liu, Liang Qiao, Qi-Yi He, Yong Zhou, Shuang Ren, Bin Chen
Thirteen cuticular proteins (CPs) families have been recognized in arthropods. In this study, 250 Anopheles sinensis CP genes were identified and named based on genome and transcriptome sequences. They were classified into 10 families based on motifs and phylogenetic analyses. In 11 other insect species, 9 had CP numbers > 150 while Apis mellifera and Tribolium castaneum had CP numbers less than 52. The CPs of 8 species occupied > 1.4% of the total genomic gene number whereas in 3 species the CPs occupied < 1%...
May 24, 2017: Insect Science
https://www.readbyqxmd.com/read/28543969/the-public-s-perception-of-the-role-of-community-pharmacists-in-wales
#2
Joanne Kember, Karen Hodson, Delyth H James
OBJECTIVE: To investigate the general public's perceptions of the community pharmacist's (CP) role in Wales by exploring understanding, awareness of services provided and potential interventions for promoting the role of CPs. METHODS: Qualitative methodology using focus group (FG) discussions exploring opinions, facilitated by a moderator (pharmacist) and an assistant. Topics discussed included the following: what a CP does; reasons for visiting; from whom they seek advice on medicines or lifestyle issues; use of traditional and newer services and promotion of services...
May 24, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28541857/a-multidisciplinary-child-protection-team-improves-the-care-of-nonaccidental-trauma-patients
#3
John M Draus
We initiated a multidisciplinary Child Protection Team (CPT) as a subgroup of our pediatric multidisciplinary trauma peer review committee. Meetings are held monthly. Nonaccidental trauma (NAT) patients from the preceding month are reviewed. The meeting has two parts. During the open part, detectives and child protective services (CPS) workers are invited to discuss specific cases. The closed part focuses on improvement of specific processes and future outcomes. Attendance is recorded and minutes are kept. We sought to review accomplishments of this group...
May 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28539093/the-impact-of-family-engagement-and-child-welfare-services-on-maltreatment-re-reports-and-substantiated-re-reports
#4
Tamara Fuller, Saijun Zhang
Despite decades of debate about the most effective ways to intervene with families reported to child protective services (CPS), little evidence exists regarding the types of services or approach that reduce children's risk of additional maltreatment. The current study used data collected during a statewide experimental evaluation of CPS to examine the impact of numerous service variables, family engagement, and family characteristics on the risk of maltreatment re-reports and substantiated re-reports among families initially reported for neglect and risk of harm...
January 1, 2017: Child Maltreatment
https://www.readbyqxmd.com/read/28537371/deconvolution-of-mass-spectral-interferences-of-chlorinated-alkanes-and-their-thermal-degradation-products-chlorinated-alkenes
#5
Lena Schinkel, Sandro Lehner, Norbert V Heeb, Peter Lienemann, Kristopher McNeill, Christian Bogdal
Chlorinated paraffins (CPs) are high production volume chemicals and ubiquitous environmental contaminants. CPs are produced and used as complex mixtures of polychlorinated n-alkanes containing thousands of isomers, leading to demanding analytical challenges. Due to their high degree of chlorination, CPs have highly complex isotopic mass patterns that often overlap, even when applying high resolution mass spectrometry. This is further complicated in the presence of degradation products such as chlorinated alkenes (CP-enes)...
May 24, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28537205/community-pharmacists-perspectives-of-online-health-related-information
#6
Ong See Wan, Mohamed Azmi Hassali, Fahad Saleem
BACKGROUND: The Internet is a resource used by health professionals as well as the public to access health information. Within this context, little is reported on community pharmacists' (CPs') perceptions of online health-related information. The objective of this study was to explore the attitudes of Malaysian CPs towards online health-related information. METHODS: A qualitative research method was adopted with face-to-face interviews, using a semi-structured interview guide...
January 1, 2017: HIM Journal
https://www.readbyqxmd.com/read/28534548/-shared-decision-making-from-the-perspective-of-the-cancer-patient-participatory-roles-and-evaluation-of-the-process
#7
N Padilla Garrido, F Aguado Correa, M Ortega Moreno, J Bayo Calero, E Bayo Lozano
BACKGROUND: In Spain there is no clear knowledge about the degree to which Shared Decision Making (SDM) is carried out in the normal practice of oncology. Our article analyses the preferred role and the perceived role of oncological patients and measures the SDM process from their perspective. MATERIAL AND METHODS: Descriptive transversal study using a self-conducted questionnaire with patients with different types of cancer. To evaluate the role preferred and perceived by the patient we used The Control Preference Scales (CPS) and to measure SDM we used The nine-item Shared Decision Making Questionnaire (SDM-Q-9)...
April 30, 2017: Anales del Sistema Sanitario de Navarra
https://www.readbyqxmd.com/read/28531193/raman-microscopy-investigation-of-vitrification-induced-structural-damages-in-mature-bovine-oocytes
#8
Giulia Rusciano, Carolina De Canditiis, Gianluigi Zito, Marcello Rubessa, Maria Serena Roca, Rosa Carotenuto, Antonio Sasso, Bianca Gasparrini
Although oocyte cryopreservation has great potentials in the field of reproductive technologies, it still is an open challenge in the majority of domestic animals and little is known on the biochemical transformation induced by this process in the different cellular compartments. Raman micro-spectroscopy allows the non-invasive evaluation of the molecular composition of cells, based on the inelastic scattering of laser photons by vibrating molecules. The aim of this work was to assess the biochemical modifications of both the zona pellucida and cytoplasm of vitrified/warmed in vitro matured bovine oocytes at different post-warming times...
2017: PloS One
https://www.readbyqxmd.com/read/28531132/effects-of-%C3%AE-carotene-and-its-cleavage-products-in-primary-pneumocyte-type-ii-cells
#9
Cornelia Haider, Franziska Ferk, Ekramije Bojaxhi, Giuseppe Martano, Hanno Stutz, Nikolaus Bresgen, Siegfried Knasmüller, Avdulla Alija, Peter M Eckl
β-Carotene has been shown to increase the risk of developing lung cancer in smokers and asbestos workers in two large scale trails, the Beta-Carotene and Retinol Efficacy Trial (CARET) and the Alpha-Tocopherol Beta-carotene Cancer Prevention Trial (ATBC). Based on this observation, it was proposed that genotoxic oxidative breakdown products may cause this effect. In support of this assumption, increased levels of sister chromatid exchanges, micronuclei, and chromosomal aberrations were found in primary hepatocyte cultures treated with a mixture of cleavage products (CPs) and the major product apo-8'carotenal...
May 21, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/28528003/acinetobacter-baumannii-k11-and-k83-capsular-polysaccharides-have-the-same-6-deoxy-l-talose-containing-pentasaccharide-k-units-but-different-linkages-between-the-k-units
#10
Johanna J Kenyon, Alexander S Shashkov, Sof'ya N Senchenkova, Mikhail M Shneider, Bin Liu, Anastasiya V Popova, Nikolay P Arbatsky, Konstantin A Miroshnikov, Lei Wang, Yuriy A Knirel, Ruth M Hall
Acinetobacter baumannii produces a variety of capsular polysaccharides (CPS) via genes located at the chromosomal K locus and some KL gene clusters include genes for the synthesis of specific sugars. The structures of K11 and K83 CPS produced by isolates LUH5545 and LUH5538, which carry related KL11a and KL83 gene clusters, respectively, were established by sugar analysis and one- and two-dimensional (1)H and (13)C NMR spectroscopy. Both CPS contain l-rhamnose (l-Rha) and 6-deoxy-l-talose (l-6dTal), and both KL gene clusters include genes for dTDP-l-Rhap synthesis and a tle (talose epimerase) gene encoding an epimerase that converts dTDP-l-Rhap to dTDP-l-6dTalp...
May 17, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28524752/widening-of-the-safe-trajectory-range-during-subaxial-cervical-pedicle-screw-placement-advantages-of-a-curved-pedicle-probe-and-laterally-located-starting-point-without-creating-a-funnel-shaped-hole
#11
Subum Lee, Junghan Seo, Moon Kyu Lee, Sang Ryong Jeon, Sung Woo Roh, Seung Chul Rhim, Jin Hoon Park
OBJECTIVE The small diameter of cervical pedicles and a large transverse cervical pedicle angle are challenges that have led spinal surgeons to investigate how they could achieve a wider safety trajectory and reduce the insertion angle during cervical pedicle screw (CPS) placement. In this paper, the authors detail the advantages of using a curved pedicle probe and a laterally located entry point for overcoming these challenges. METHODS From March 2012 to May 2016, the authors performed posterior cervical fusions using CPSs on 119 consecutive patients...
May 19, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28521464/integration-of-child-pugh-score-with-future-liver-remnant-yields-improved-prediction-of-liver-dysfunction-risk-for-hbv-related-hepatocellular-carcinoma-following-hepatic-resection
#12
Heng Zou, Yiming Tao, Zhi-Ming Wang
Assessment of hepatic functional reserve is important to enable the selection of appropriate treatment methods and safe hepatic resection in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). In the present study, an evaluation was made of the clinical value of combining the Child-Pugh score (CPS) with the standardized future liver remnant (sFLR) measurement to predict postoperative liver dysfunction (PLD). A total of 61 HBV-related HCC patients undergoing liver volumetry prior to hepatectomy were enrolled in the study...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28516843/potentially-hazardous-streptococcus-suis-strains-latent-in-asymptomatic-pigs-in-a-major-swine-production-area-of-thailand
#13
Nattakan Meekhanon, Sarawan Kaewmongkol, Waraphon Phimpraphai, Masatoshi Okura, Makoto Osaki, Tsutomu Sekizaki, Daisuke Takamatsu
PURPOSE: Carrier pigs have been considered as the major reservoir of Streptococcus suis and couldbe a significant source of human infection. Therefore, we investigated the prevalence and characteristics of latent S. suis in asymptomatic pigs in the pig-farming area of central Thailand, and compared the data to those previously reported in other regions. METHODOLOGY: We collected samples from 340 asymptomatic pigs. S. suis isolates from the samples were confirmed by species-specific PCR (recN PCR)...
May 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28513297/former-food-products-safety-microbiological-quality-and-computer-vision-evaluation-of-packaging-remnants-contamination
#14
M Tretola, A R Di Rosa, E Tirloni, M Ottoboni, C Giromini, F Leone, C E M Bernardi, V Dell'Orto, V Chiofalo, L Pinotti
The use of alternative feed ingredients in farm animal's diets can be an interesting choice from several standpoints, including safety. In this respect, the aim of this study was to investigate the safety features of selected Former Food Products (FFPs) intended for animal nutrition produced in the framework of IZS PLV 06/14 RC project by a FFP processing plant. Six FFP samples, both mash and pelleted, were analysed for the enumeration of Total Viable Count (TVC) (ISO 4833), Enterobacteriaceae (ISO 21528-1), Escherichia coli (ISO 16649-1), coagulase-positive Staphylococci (CPS) (ISO 6888), presumptive B...
May 17, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/28508857/controlling-photophysical-properties-of-ultrasmall-conjugated-polymer-nanoparticles-through-polymer-chain-packing
#15
Hubert Piwoński, Tsuyoshi Michinobu, Satoshi Habuchi
Applications of conjugated polymer nanoparticles (Pdots) for imaging and sensing depend on their size, fluorescence brightness and intraparticle energy transfer. The molecular design of conjugated polymers (CPs) has been the main focus of the development of Pdots. Here we demonstrate that proper control of the physical interactions between the chains is as critical as the molecular design. The unique design of twisted CPs and fine-tuning of the reprecipitation conditions allow us to fabricate ultrasmall (3...
May 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/28503949/silymarin-nanoemulsion-against-human-hepatocellular-carcinoma-development-and-optimization
#16
Usama Ahmad, Juber Akhtar, Satya Prakash Singh, Farhan Jalees Ahmad, Sahabjada Siddiqui
OBJECTIVE: Nanoemulsion of silymarin was developed and optimized. MATERIALS AND METHODS: Nanoemulsion was made by aqueous titration method. Sefsol 218 (5.8% v/v), Kolliphor RH40 and polyethylene glycol 400 (Smix; 2:1; 28.99% v/v) were used as oil phase, surfactant and co-surfactant while distilled water (65.22% v/v) acted as an aqueous phase. Nanoemulsion was characterized on the basis of particle size, viscosity, electrical conductivity and refractive index. Further, in vitro release, in vivo pharmacokinetic study, stability study and cancer cell line studies were also performed...
May 14, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28500561/study-of-%C3%AE-catenin-and-braf-alterations-in-adamantinomatous-and-papillary-craniopharyngiomas-mutation-analysis-with-immunohistochemical-correlation-in-54-cases
#17
Prit Benny Malgulwar, Aruna Nambirajan, Pankaj Pathak, Mohammed Faruq, Vaishali Suri, Chitra Sarkar, Amandeep Jagdevan, Bhawani Shankar Sharma, Mehar Chand Sharma
Craniopharyngiomas (CP) are rare benign epithelial tumors, with two histological variants, namely the adamantinomatous variant (ACP) and the rarer papillary variant (PCP). They are locally infiltrative and surgically challenging tumors with severe long term morbidity. CTNNB1 mutations with β-catenin immunopositivity and BRAFV600E mutations with anti-VE immunopositivity have been recently described in ACPs and PCPs respectively. We aimed to study BRAF and CTNNB1 gene mutations in CPs operated at our institute, and correlate it with clinicopathological parameters including histopathology and immunohistochemistry (IHC) for proteins VE-1 and β-catenin...
May 12, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28495967/streptococcus-pneumoniae-capsular-polysaccharide-is-linked-to-peptidoglycan-via-a-direct-glycosidic-bond-to-%C3%AE-d-n-acetylglucosamine
#18
Thomas R Larson, Janet Yother
For many bacteria, including those important in pathogenesis, expression of a surface-localized capsular polysaccharide (CPS) can be critical for survival in host environments. In Gram-positive bacteria, CPS linkage is to either the cytoplasmic membrane or the cell wall. Despite the frequent occurrence and essentiality of these polymers, the exact nature of the cell wall linkage has not been described in any bacterial species. Using the Streptococcus pneumoniae serotype 2 CPS, which is synthesized by the widespread Wzy mechanism, we found that linkage occurs via the reducing end glucose of CPS and the β-D-N-acetylglucosamine (GlcNAc) residues of peptidoglycan (PG)...
May 11, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28493922/comparison-of-the-long-term-clinical-performance-of-a-biodegradable-and-a-titanium-fixation-system-in-maxillofacial-surgery-a-multicenter-randomized-controlled-trial
#19
B Gareb, N B van Bakelen, G J Buijs, J Jansma, J G A M de Visscher, Th J M Hoppenreijs, J E Bergsma, B van Minnen, B Stegenga, R R M Bos
BACKGROUND: Biodegradable fixation systems could reduce or eliminate problems associated with titanium removal of implants in a second operation. AIM: The aim of this study was to compare the long-term (i.e. >5 years postoperatively) clinical performance of a titanium and a biodegradable system in oral and maxillofacial surgery. MATERIALS AND METHODS: The present multicenter Randomized Controlled Trial (RCT) was performed in four hospitals in the Netherlands...
2017: PloS One
https://www.readbyqxmd.com/read/28489473/treatment-of-recalcitrant-plantar-warts-with-long-pulsed-nd-yag-laser-versus-cantharidin-podophylline-resin-salicylic-acid
#20
Soheir Ghonemy
BACKGROUND: Treatment for recalcitrant plantar warts remains a continuing challenge as the options for treatment have differing levels of success. Long-Pulsed Nd: YAG Laser is considered a good treatment modality in resistant plantar warts. On the other hand high, cure rates have been reported with a topical proprietary formulation consisting of 1% cantharidin, 5% podophyllotoxin, 30% salicylic acid. AIM: To compare the efficacy of 1% cantharidin, 20% podophylline resin, 30% salicylic acid (CPS) versus Long-Pulsed Nd:YAG Laser in the treatment of recalcitrant plantar warts...
May 10, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
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