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Aria Seo, Junho Jeong, Yeichang Kim
As the sharing economic market grows, the number of users is also increasing but many problems arise in terms of reliability between providers and users in the processing of services. The existing methods provide shared economic systems that judge the reliability of the provider from the viewpoint of the user. In this paper, we have developed a system for establishing mutual trust between providers and users in a shared economic environment to solve existing problems. In order to implement a system that can measure and control users' situation in a shared economic environment, we analyzed the necessary factors in a cyber physical system (CPS)...
August 13, 2017: Sensors
Chao Li, Xin Chen, Fuyuan Zhang, Xingxing He, Guozhen Fang, Jifeng Liu, Shuo Wang
Glucose assay is of great scientific significance in clinical diagnostics and bioprocess monitoring and to design new glucose receptor is necessary for development of more sensitive, selective and robust glucose detection techniques. Herein, a series of cyclic peptides (CPs) glucose receptor were designed to mimic the binding sites of glucose binding protein (GBP) and CPs' sequence contained amino acid sites Asp, Asn, His, Asp, Arg, which constituted the first layer interactions of GBP. The properties of these CPs used as a glucose receptor or substitute for the GBP were studied by using quartz crystal microbalance (QCM) technique...
August 14, 2017: Analytical Chemistry
Alison R Allukian, Amanda L Abelson, Jonathan Babyak, Elizabeth A Rozanski
OBJECTIVE: To compare the time required and the success rate of personnel with 4 different levels of experience to place a humeral intraosseous (IO) catheter versus a jugular venous catheter (IV) in cadaver dogs. DESIGN: Prospective study. SETTING: Veterinary university teaching hospital. INTERVENTIONS: Canine cadavers from recently euthanized dogs were obtained from the cadaver donation program between May and December 2014...
August 10, 2017: Journal of Veterinary Emergency and Critical Care
Patrick Ebner, Arif Luqman, Sebastian Reichert, Ksenia Hauf, Peter Popella, Karl Forchhammer, Michael Otto, Friedrich Götz
Release of cytoplasmic proteins into the supernatant occurs both in bacteria and eukaryotes. Because the underlying mechanism remains unclear, the excretion of cytoplasmic proteins (ECP) has been referred to as "non-classical protein secretion." We show that none of the known specific protein transport systems of Gram-positive bacteria are involved in ECP. However, the expression of the cationic and amphipathic α-type phenol-soluble modulins (PSMs), particularly of PSMα2, significantly increase ECP, while PSMβ peptides or δ-toxin have no effect on ECP...
August 8, 2017: Cell Reports
Arun Agarwal, Manju Goyal, Jainendra Jain, Aakanksha Agarwal
Whether preceded by preeclampsia, or occuring without antecedent warning symptoms, eclamptic seizures usually occur in the antepartum period between 20 and 40 weeks of gestation or within a few hours to 2 days postpartum. We report the case of a patient with pre-eclampsia who developed seizures after more than 2 days of delivery. In view of late onset postpartum seizures and non-responsiveness to magnesium sulphate, she was further evaluated and diagnosed to have congenital perisylvian syndrome(CPS). In CPS, polymicrogyric cortex is distributed in variable extensions around the sylvian fissure i...
June 2017: Journal of the Association of Physicians of India
Lindsey M Rodriguez, Karen Chan Osilla, Thomas E Trail, Kristie L Gore, Eric R Pedersen
Heavy drinking in relationships is complex and we focus on an understudied sample of concerned partners (CPs) worried about their U.S. service member/veteran partner's drinking. We evaluated the link between CP drinking and their own mental health, and how CP drinking moderated the efficacy of a web-based intervention designed to address CPs' mental health and communication. CPs (N = 234) were randomly assigned to intervention or control and completed assessments at baseline and 5 months later. CP drinking was associated with greater CP depression, anxiety, and anger independent of partner drinking...
August 7, 2017: Journal of Marital and Family Therapy
Emerson N Itikawa, Leonardo A Santos, Ana C Trevisan, Felipe A Pitella, Mery Kato, Eder R Moraes, Lauro Wichert-Ana
OBJECTIVE: The aim of this study was to evaluate angular, spatial, and energy resolution, sensitivity, and shielding of a gamma-probe. MATERIALS AND METHODS: The EUROPROBE II gamma-probe (EuroRad) with sources of technetium-99m was assessed according to NEMA NU-3-2004. Resolution tests were evaluated considering the full width at half maximum (FWHM). The following parameters were evaluated: angular resolution in air, spatial resolution with a scattering medium and in air, energy resolution, and sensitivity and shielding...
August 3, 2017: Nuclear Medicine Communications
Jennifer Tjia, Marisa Dharmawardene, Jane L Givens
OBJECTIVE: To describe prevalence and content of AD documentation among NH residents by dementia stage. BACKGROUND: The prevalence of advance directives (ADs) among nursing home (NH) residents with mild, moderate, and advanced dementia remains unclear. METHODS: Population-based, cross-sectional study of all licensed NHs in five U.S. states. Subjects included all long-stay (>90 day) NH residents with dementia, aged ≥65 years, and a Cognitive Performance Scale (CPS) score ≥1 from the 2007 to 2008 Minimum Data Set 2...
August 3, 2017: Journal of Palliative Medicine
Xiangyang Li, Gefei Hao, Qingmin Wang, Zhuo Chen, Yan Ding, Lu Yu, Deyu Hu, Baoan Song
Tobacco mosaic virus (TMV) causes severe plant diseases worldwide; however, effective antiviral agents for controlling TMV infections are not available. This lack of effective antiviral agents is mainly due to the poor understanding of potential targets associated with TMV infections. During infection, the coat protein (CP), which is delivered by viral particles into susceptible host cells, provides protection for viral RNA. Here, we found that Ningnanmycin (NNM), a commercially used plant antibacterial agent, inhibits the assembly of the CP by directly binding several residues...
July 19, 2017: Oncotarget
Jorge Berzosa Macho, Luis Gardeazabal Montón, Roberto Cortiñas Rodriguez
The Cyber Physical Systems (CPS) paradigm is based on the deployment of interconnected heterogeneous devices and systems, so interoperability is at the heart of any CPS architecture design. In this sense, the adoption of standard and generic data formats for data representation and communication, e.g., XML or JSON, effectively addresses the interoperability problem among heterogeneous systems. Nevertheless, the verbosity of those standard data formats usually demands system resources that might suppose an overload for the resource-constrained devices that are typically deployed in CPS...
August 1, 2017: Sensors
Xianyu Huang, Daoliang Chen, Mingrui He, Jianfeng Li, Jiawei Huang, Baolin Li
Four novel coordination polymers (CPs) assembled with [2,2'-bifuran]-5,5'-dicarboxylic acid (H2L) and metal ions Zn(II), Cd(II) or Co(II) have been successfully synthesized. Their molecular structures have been determined to be Zn(L)(H2O)2 (1), [Zn(L)(DMF)]2 (2), [Cd(L)(EtOH)(DMF)2]2 (3) and Co(L)(H2O)4·(H2O)2 (4) by crystallographic analysis. It is found that (2) exhibits a two-dimensional infinite framework, whereas the others exhibit a one-dimensional framework. Both (2) and (3) exhibit ligand-based emission which is blue-shifted compared with the emission from the H2L ligand...
August 1, 2017: Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials
Eskandar Moghimipour, Anayatollah Salimi, Sahar Changizi
Purpose: The objective of the present study is to formulate and evaluate a new microemulsion (ME) for topical delivery of griseofulvin. Methods: The solubilities of griseofulvin in different combinations of surfactant to co-surfactant (S/Co ratio) were determined. Accordingly, based on their phase diagrams, eight microemulsions were formulated and then evaluated with respect to their particle size, surface tension, viscosity, conductivity, zeta potential and stability. Their release behavior, Scanning Electron Microscopy (SEM), Differential Scanning Calorimetry (DSC), refractory index (RI), pH and Small-angle-X-ray scattering (SAXS) were also assessed...
June 2017: Advanced Pharmaceutical Bulletin
Nilay Yilmaz, Ece Eksin, Bilge Karacicek, Yasemin Eraç, Arzum Erdem
In this study, the biomolecular interaction occured between nucleic acids and Capsaicin (CPS), the active compound in chilli peppers, which has been reported to have anti-carcinogenic properties, was investigated for the first time herein using disposable electrochemical biosensor. It is aimed to perform the surface-confined interaction between CPS and different types of nucleic acids and under this aim, the experimental conditions were optimized; such as, the concentration of CPS and DNA, DNA immobilizaton time and interaction time etc...
July 28, 2017: Analytical Biochemistry
Hideki Osaki, Atsuko Sasaki, Eiko Nakazono-Nagaoka, Nobuyoshi Ota, Ryoji Nakaune
According to previous studies, three double-stranded (ds) RNA molecules (dsRNA1, 2, and 3) detected in Japanese pear are transmitted to the next generation with high frequency through both ovules and pollen. Nucleotide sequence analysis of dsRNA1-encoding RNA-dependent RNA polymerase (RdRp) has suggested that these dsRNAs are related to a cryptovirus named Pyrus pyrifolia cryptic virus (PpCV). In this study, purified dsRNA prepared from a PpCV-infected Japanese pear cultivar was subjected to next-generation deep sequencing...
July 29, 2017: Virus Research
M F Moedas, A A A Adam, M A Farelo, L IJlst, R A F M Chamuleau, R Hoekstra, R J A Wanders, M F B Silva
Current methodologies for the assessment of urea cycle (UC) enzymatic activity are insufficient to accurately evaluate this pathway in biological specimens where lower UC is expected. Liver cell lines, including HepaRG, have been described to have limited nitrogen fixation through the UC, limiting their applicability as biocomponents for Bioartificial Livers (BAL). This work aims to develop novel and sensitive analytical solutions using Mass Spectrometry-based methodology to measure the activity of four UC enzymes in human liver and HepaRG cells...
July 27, 2017: Analytical Biochemistry
Megan Finno-Velasquez, Lindsey Palmer, John Prindle, Christina C Tam, Emily Putnam-Hornstein
Research identifying racial and ethnic disparities in child protective services (CPS) involvement in the U.S. has focused on the overrepresentation of Black children and the growing Latino child population. Little attention has been paid to children of Asian origin, the most underrepresented group of children in the U.S. CPS system. The objective of this analysis was to examine subgroup patterns of CPS involvement in California for Asian and Pacific Islander (API) children prospectively based on maternal nativity and ethnic origin...
July 27, 2017: Child Abuse & Neglect
Mitsuo Watanabe, Akinori Saito, Takashi Isobe, Kibo Ote, Ryoko Yamada, Takahiro Moriya, Tomohide Omura
A high-resolution positron emission tomography (PET) scanner dedicated to brain studies was developed, and its performance was evaluated. A four-layer depth of interaction (DOI) detector was designed; it contains five detector units axially lined up per layer board. Each of the detector units consists of a LYSO scintillator array finely segmented (1.2 mm) and an 8 × 8 array of multi-pixel photon counters (MPPCs). The new scanner was designed to form a detector ring of 430-mm diameter with 32 detector modules and 168 detector rings with a 1...
July 28, 2017: Physics in Medicine and Biology
Van-Trinh Luu, Hye Yun Moon, Jee Youn Hwang, Bo-Kyu Kang, Hyun Ah Kang
Nervous necrosis virus (NNV) causes viral encephalopathy and retinopathy, a devastating disease of many species of cultured marine fish worldwide. In this study, we used the dimorphic non-pathogenic yeast Yarrowia lipolytica as a host to express the capsid protein of red-spotted grouper nervous necrosis virus (RGNNV-CP) and evaluated its potential as a platform for vaccine production. An initial attempt was made to express the codon-optimized synthetic genes encoding intact and N-terminal truncated forms of RGNNV-CP under the strong constitutive TEF1 promoter using autonomously replicating sequence (ARS)-based vectors...
August 2017: Journal of Microbiology / the Microbiological Society of Korea
Linda Nguyen, Karim Keshavjee, Norm Archer, Christopher Patterson, Femida Gwadry-Sridhar, Catherine Demers
BACKGROUND: In North America, heart failure (HF) is the leading cause for hospital readmission. Supportive technology, such as computers and tablets, could potentially assist patients with self-care to manage their condition after hospital discharge; however, older individuals have difficulties in adopting technology to manage their condition. METHOD: This study used a mixed methods design to identify barriers to technology use in HF self-care. In the qualitative phase, semi-structured interviews were conducted with 18 HF patients and 10 informal caregivers or care partners (CP)...
September 2017: International Journal of Medical Informatics
Shu-Hong Zhu, Yue-Lin Zhuang, Shiushing Wong, Sharon E Cummins, Gary J Tedeschi
Objective To examine whether the increase in use of electronic cigarettes in the USA, which became noticeable around 2010 and increased dramatically by 2014, was associated with a change in overall smoking cessation rate at the population level.Design Population surveys with nationally representative samples.Setting Five of the US Current Population Survey-Tobacco Use Supplement (CPS-TUS) in 2001-02, 2003, 2006-07, 2010-11, and 2014-15.Participants Data on e-cigarette use were obtained from the total sample of the 2014-15 CPS-TUS (n=161 054)...
July 26, 2017: BMJ: British Medical Journal
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