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https://www.readbyqxmd.com/read/28231239/surveillance-for-health-care-access-and-health-services-use-adults-aged-18-64-years-behavioral-risk-factor-surveillance-system-united-states-2014
#1
Catherine A Okoro, Guixiang Zhao, Jared B Fox, Paul I Eke, Kurt J Greenlund, Machell Town
PROBLEM/CONDITION: As a result of the 2010 Patient Protection and Affordable Care Act, millions of U.S. adults attained health insurance coverage. However, millions of adults remain uninsured or underinsured. Compared with adults without barriers to health care, adults who lack health insurance coverage, have coverage gaps, or skip or delay care because of limited personal finances might face increased risk for poor physical and mental health and premature mortality. PERIOD COVERED: 2014...
February 24, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/28230725/towards-a-semantic-web-of-things-a-hybrid-semantic-annotation-extraction-and-reasoning-framework-for-cyber-physical-system
#2
Zhenyu Wu, Yuan Xu, Yunong Yang, Chunhong Zhang, Xinning Zhu, Yang Ji
Web of Things (WoT) facilitates the discovery and interoperability of Internet of Things (IoT) devices in a cyber-physical system (CPS). Moreover, a uniform knowledge representation of physical resources is quite necessary for further composition, collaboration, and decision-making process in CPS. Though several efforts have integrated semantics with WoT, such as knowledge engineering methods based on semantic sensor networks (SSN), it still could not represent the complex relationships between devices when dynamic composition and collaboration occur, and it totally depends on manual construction of a knowledge base with low scalability...
February 20, 2017: Sensors
https://www.readbyqxmd.com/read/28229112/chronic-psychosocial-stressors-in-adulthood-studies-in-mice-rats-and-tree-shrews
#3
REVIEW
Christopher R Pryce, Eberhard Fuchs
Human psychological stress is the major environmental risk factor for major depression and certain of the anxiety disorders. Psychological stressors often occur in the context of the adult social environment, and they or the memory formed of them impact on the individual across an extended period, thereby constituting chronic psychosocial stress (CPS). Psychosocial stressors often involve loss to the individual, such as the ending of a social relationship or the onset of interpersonal conflict leading to loss of social control and predictability...
February 2017: Neurobiology of Stress
https://www.readbyqxmd.com/read/28228857/total-synthesis-of-a-streptococcus-pneumoniae-serotype-12f-cps-repeating-unit-hexasaccharide
#4
Peter H Seeberger, Claney L Pereira, Subramanian Govindan
The Gram-positive bacterium Streptococcus pneumoniae causes severe disease globally. Vaccines that prevent S. pneumoniae infections induce antibodies against epitopes within the bacterial capsular polysaccharide (CPS). A better immunological understanding of the epitopes that protect from bacterial infection requires defined oligosaccharides obtained by total synthesis. The key to the synthesis of the S. pneumoniae serotype 12F CPS hexasaccharide repeating unit that is not contained in currently used glycoconjugate vaccines is the assembly of the trisaccharide β-D-GalpNAc-(1→4)-[α-D-Glcp-(1→3)]-β-D-ManpNAcA, in which the branching points are equipped with orthogonal protecting groups...
2017: Beilstein Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28224641/trends-in-volunteer-mentoring-in-the-united-states-analysis-of-a-decade-of-census-survey-data
#5
Elizabeth B Raposa, Nathan Dietz, Jean E Rhodes
Over the past decade, considerable resources have been devoted to recruiting volunteer mentors and expanding mentoring programs. It is unclear whether these efforts have helped to counter the broader national trends of declining volunteer rates. The current study uses data from the Volunteering Supplement of the Current Population Survey (CPS), sponsored by the U.S. Census Bureau and U.S. Bureau of Labor Statistics, to explore population-level trends in mentoring over the past decade. Results suggest that mentoring rates have remained relatively stable over the past decade, but that the population of mentors has changed somewhat in terms of age, ethnicity, educational background, and region of the United States...
February 22, 2017: American Journal of Community Psychology
https://www.readbyqxmd.com/read/28222782/identification-of-mirna-mrna-crosstalk-in-cd4-t-cells-during-hiv-1-infection-by-integrating-transcriptome-analyses
#6
Qibin Liao, Jin Wang, Zenglin Pei, Jianqing Xu, Xiaoyan Zhang
BACKGROUND: HIV-1-infected long-term nonprogressors (LTNPs) are characterized by infection with HIV-1 more than 7-10 years, but keeping high CD4(+) T cell counts and low viral load in the absence of antiretroviral treatment, while loss of CD4(+) T cells and high viral load were observed in the most of HIV-1-infected individuals with chronic progressors (CPs) However, the mechanisms of different clinical outcomes in HIV-1 infection needs to be further resolved. METHODS: To identify microRNAs (miRNAs) and their target genes related to distinct clinical outcomes in HIV-1 infection, we performed the integrative transcriptome analyses in two series GSE24022 and GSE6740 by GEO2R, R, TargetScan, miRDB, and Cytoscape softwares...
February 21, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28222594/high-throughput-determination-and-characterization-of-short-medium-and-long-chain-chlorinated-paraffins-in-human-blood
#7
Tong Li, Yi Wan, Shixiong Gao, Beili Wang, Jianying Hu
The industrial chlorinated paraffins (CPs) are comprised of short-chain (SCCPs), medium chain (MCCPs), and long chain (LCCPs) CPs. Although SCCPs and MCCPs are environmentally ubiquitous, little is known about CPs in humans. This study established a method for simultaneous determination of 261 SCCP, MCCP, and LCCP congener groups in one injection by reversed ultra-high-pressure liquid chromatography coupled with chlorine-enhanced electron spray ionization-quadrupole time-of-flight mass spectrometry. The method yielded good peak shapes, high sensitivities, and low co-eluted interferences for all examined CPs...
February 22, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28221920/prevalence-and-molecular-characterization-of-methicillin-resistant-staphylococcus-aureus-in-foods-of-animal-origin-turkey
#8
Belgin Siiriken, Tuba Yildirim, Akif Koray Güney, Irfan Erol, Belma Durupinar
In the present study, 175 coagulase-positive Staphylococcus (CPS) isolates recovered from samples of beef (n = 110), raw milk n = 56), and fish (n = 9) were analyzed for methicillin resistance using MIC and PCR assays. Methicillin-resistant (MR) Staphylococcus aureus (SA) isolates were then characterized using pulsed-field gel electrophoresis (PFGE). According to findings, 62 (35.4%) of the isolates (44 from beef, 9 from milk, and 9 from fish) were identified as S. aureus based on the presence of the nuc gene...
November 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28219415/genotyping-and-investigating-capsular-polysaccharide-synthesis-gene-loci-of-non-serotypeable-streptococcus-suis-isolated-from-diseased-pigs-in-canada
#9
Han Zheng, Xiaotong Qiu, David Roy, Mariela Segura, Pengchen Du, Jianguo Xu, Marcelo Gottschalk
Streptococcus suis (S. suis) is an important swine pathogen and an emerging zoonotic agent. Most clinical S. suis strains express capsular polysaccharides (CPS), which can be typed by antisera using the coagglutination test. In this study, 79 S. suis strains recovered from diseased pigs in Canada and which could not be typed using antisera were further characterized by capsular gene typing and sequencing. Four patterns of cps locus were observed: (1) fifteen strains were grouped into previously reported serotypes but presented several mutations in their cps loci, when compared to available data from reference strains; (2) seven strains presented a complete deletion of the cps locus, which would result in an inability to synthesize capsule; (3) forty-seven strains were classified in recently described novel cps loci (NCLs); and (4) ten strains carried novel NCLs not previously described...
February 20, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28218842/medium-chain-chlorinated-paraffins-cps-dominate-in-australian-sewage-sludge
#10
Sicco Hendrik Brandsma, Louise van Mourik, Jake William O'Brien, Geoff Eaglesham, Pim E G Leonards, Jacob De Boer, Christie Gallen, Jochen F Mueller, Caroline Gaus, Christian Bogdal
To simultaneously quantify and profile the complex mixture of short-, median-, and long-chain CPs (SCCPs, MCCPs and LCCPs) in Australian sewage sludge, we applied and further validated a recently developed novel instrumental technique, using quadrupole time-of-flight high resolution mass spectrometry running in the negative atmospheric pressure chemical ionization mode (APCI-qTOF-HRMS). Without using an analytical column the cleaned extracts were directly injected into the qTOF-HRMS followed by quantification of the CPs by a mathematical algorithm...
February 20, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28217109/e-coli-group-1-capsular-polysaccharide-exportation-nanomachinary-as-a-plausible-antivirulence-target-in-the-perspective-of-emerging-antimicrobial-resistance
#11
REVIEW
Shivangi Sachdeva, Raghuvamsi V Palur, Karpagam U Sudhakar, Thenmalarchelvi Rathinavelan
Bacteria evolving resistance against the action of multiple drugs and its ability to disseminate the multidrug resistance trait(s) across various strains of the same bacteria or different bacterial species impose serious threat to public health. Evolution of such multidrug resistance is due to the fact that, most of the antibiotics target bacterial survival mechanisms which exert selective pressure on the bacteria and aids them to escape from the action of antibiotics. Nonetheless, targeting bacterial virulence strategies such as bacterial surface associated polysaccharides biosynthesis and their surface accumulation mechanisms may be an attractive strategy, as they impose less selective pressure on the bacteria...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28213928/problem-solving-phase-transitions-during-team-collaboration
#12
Travis J Wiltshire, Jonathan E Butner, Stephen M Fiore
Multiple theories of problem-solving hypothesize that there are distinct qualitative phases exhibited during effective problem-solving. However, limited research has attempted to identify when transitions between phases occur. We integrate theory on collaborative problem-solving (CPS) with dynamical systems theory suggesting that when a system is undergoing a phase transition it should exhibit a peak in entropy and that entropy levels should also relate to team performance. Communications from 40 teams that collaborated on a complex problem were coded for occurrence of problem-solving processes...
February 18, 2017: Cognitive Science
https://www.readbyqxmd.com/read/28209434/spatial-and-temporal-trends-of-short-and-medium-chain-chlorinated-paraffins-in-sediments-off-the-urbanized-coastal-zones-in-china-and-japan-a-comparison-study
#13
Lixi Zeng, James C W Lam, Yuichi Horii, Xiaolin Li, Weifang Chen, Jian-Wen Qiu, Kenneth M Y Leung, Eriko Yamazaki, Nobuyoshi Yamashita, Paul K S Lam
To examine the impacts of urbanization and industrialization on the coastal environment, and assess the effectiveness of control measures on the contamination by chlorinated paraffins (CPs) in East Asia, surface and core sediments were sampled from the urbanized coastal zones in China and Japan (i.e., Pearl River Delta (PRD), Hong Kong waters and Tokyo Bay) and analyzed for short-chain (SCCPs) and medium-chain CPs (MCCPs). Much higher concentrations of CPs were found in the industrialized PRD than in adjacent Hong Kong waters...
February 13, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28207248/mechanochemical-and-conventional-synthesis-of-zn-ii-cd-ii-luminescent-coordination-polymers-dual-sensing-probe-for-selective-detection-of-chromate-anions-and-tnp-in-aqueous-phase
#14
Bhavesh Parmar, Yadagiri Rachuri, Kamal Kumar Bisht, Ridhdhi Laiya, Eringathodi Suresh
Isostructural Zn(II)/Cd(II) mixed ligand coordination polymers (CPs) {[M(IPA)(L)]}n (CP1 and CP2) built from isophthalic acid (H2IPA) and 3-pyridylcarboxaldehyde nicotinoylhydrazone (L) were prepared using versatile synthetic routes: viz., diffusion of precursor solutions, conventional reflux methods, and green mechanochemical (grinding) reactions. Both robust CPs synthesized by different routes were characterized by various analytical methods, and their thermal and chemical stability as well as the phase purity was established...
February 16, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28203522/mass-spectral-determination-of-phosphopantetheinylation-specificity-for-carrier-proteins-in-mycobacterium-tuberculosis
#15
James Jung, Ghader Bashiri, Jodie M Johnston, Edward N Baker
Phosphopantetheinyl transferases (PPTases) are key elements in the modular syntheses performed by multienzyme systems such as polyketide synthases. PPTases transfer phosphopantetheine derivatives from Coenzyme A to carrier proteins (CPs), thus orchestrating substrate supply. We describe an efficient mass spectrometry-based protocol for determining CP specificity for a particular PPTase in organisms possessing several candidate PPTases. We show that the CPs MbtL and PpsC, both involved in synthesis of essential metabolites in Mycobacterium tuberculosis, are exclusively activated by the type 2 PPTase PptT and not the type 1 AcpS...
December 2016: FEBS Open Bio
https://www.readbyqxmd.com/read/28203039/quality-assurance-using-outlier-detection-on-an-automatic-segmentation-method-for-the-cerebellar-peduncles
#16
Ke Li, Chuyang Ye, Zhen Yang, Aaron Carass, Sarah H Ying, Jerry L Prince
Cerebellar peduncles (CPs) are white matter tracts connecting the cerebellum to other brain regions. Automatic segmentation methods of the CPs have been proposed for studying their structure and function. Usually the performance of these methods is evaluated by comparing segmentation results with manual delineations (ground truth). However, when a segmentation method is run on new data (for which no ground truth exists) it is highly desirable to efficiently detect and assess algorithm failures so that these cases can be excluded from scientific analysis...
February 27, 2016: Proceedings of SPIE
https://www.readbyqxmd.com/read/28194713/use-of-compressive-osseointegration-endoprostheses-for-massive-bone-loss-from-tumor-and-failed-arthroplasty-a-viable-option-in-the-upper-extremity
#17
Krista A Goulding, Adam Schwartz, Steven J Hattrup, R Lor Randall, Donald Lee, Damian M Rispoli, Daniel M Lerman, Christopher Beauchamp
BACKGROUND: Endoprostheses using principles of compressive osseointegration have shown good survivorship in several studies involving the lower extremity; however, no series to our knowledge have documented the use of this technology in the management of massive bone loss in the upper limb. QUESTIONS/PURPOSES: (1) What proportion of upper extremity implants using compressive osseointegration fixation principles achieved durable short-term fixation, and what were the modes of failure? (2) What surgical complications resulted from reconstruction using this technique? METHODS: A multiinstitutional retrospective review identified nine patients (five women; four men) who underwent 13 endoprosthetic replacements between 2003 and 2014 using compressive osseointegration (Compliant(®) Pre-stress Device [CPS]; Biomet Inc, Warsaw, IN, USA) in the upper extremity, including two proximal humeri, two humeral diaphyses, seven distal humeri, and two proximal ulna...
February 13, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28194471/rigid-versus-semi-rigid-bis-imidazole-ligands-in-the-assembly-of-two-co-ii-coordination-polymers-structural-variability-electrochemical-properties-and-photocatalytic-behavior
#18
Jing-Wang Cui, Suo-Xia Hou, Kristof Van Hecke, Guang-Hua Cui
The hydrothermal reactions of 1,2,4,5-cyclohexanetetracarboxylic acid (H4L) with CoCl2·2H2O and rigid or semi-rigid bis(imidazole) ligands were able to generate two Co(ii) coordination polymers (CPs), {[Co5(L)2(1,4-bimb)(μ3-OH)2(H2O)8]·2H2O}n (1), {[Co(L)0.5(1,4-bib)]·H2O}n (2) (1,4-bimb = 1,4-bis(imidazol-1-ylmethyl)benzene, 1,4-bib = 1,4-bis(1H-imidazol-1-yl)benzene). CPs 1 and 2 were structurally characterized by elemental analysis, IR spectroscopy, X-ray powder diffraction and single crystal X-ray diffraction...
February 14, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28194259/anti-inflammatory-activity-of-a-sulfated-polysaccharide-isolated-from-an-enzymatic-digest-of-brown-seaweed-sargassum-horneri-in-raw-264-7-cells
#19
Kalu Kapuge Asanka Sanjeewa, Ilekkuttige Priyan Shanura Fernando, Eun-A Kim, Ginnae Ahn, Youngheun Jee, You-Jin Jeon
BACKGROUND/OBJECTIVES: Sargassum horneri is an edible brown alga that grows in the subtidal zone as an annual species along the coasts of South Korea, China, and Japan. Recently, an extreme amount of S. horneri moved into the coasts of Jeju Island from the east coast of China, which made huge economic and environmental loss to the Jeju Island. Thus, utilization of this biomass becomes a big issue with the local authorities. Therefore, the present study was performed to evaluate the anti-inflammatory potential of crude polysaccharides (CPs) extracted from S...
February 2017: Nutrition Research and Practice
https://www.readbyqxmd.com/read/28190743/a-medically-relevant-capsular-polysaccharide-in-acinetobacter-baumannii-is-a-potential-vaccine-candidate
#20
Feng-Ling Yang, Tze-Chi Lou, Shu-Chen Kuo, Wan-Ling Wu, Jeffy Chern, Yi-Tzu Lee, Shui-Tsung Chen, Wei Zou, Nien-Tsung Lin, Shih-Hsiung Wu
Concerns of Acinetobacter baumannii infection have increased due to the emergence of multi-drug resistance. In the present study, we determined the capsular polysaccharide (CPS) structure of A. baumannii SK44, a clinical isolate from Taiwan, to consist of pentasaccharide repeats. We found that CPS-induced antibody provided 55% protection against challenge in an animal model. The CPS-specific antibody reacted with the surface components of about 62% clinical isolates (342/554 strains) from cross-sectional and longitudinal studies by dot-immunoassay...
February 9, 2017: Vaccine
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