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https://www.readbyqxmd.com/read/28729954/clinical-streptococcal-isolates-distinct-from-streptococcus-pneumoniae-but-containing-the-%C3%AE-glucosyltransferase-tts-gene-and-expressing-serotype-37-capsular-polysaccharide
#1
Carmen L Sheppard, Georgia Kapatai, Karen Broughton, Ulf Schaefer, Matthew Hannah, David J Litt, Norman K Fry
The major virulence factor of the pneumococcus, and target for conjugate vaccines, is the polysaccharide capsule, which is usually encoded by the highly variable cps locus. Serotype 37 is an unusual pneumococcal type in which the single β-glucosyltransferase gene responsible for serotype capsule production (tts) is located outside of the capsular operon region. Using a previously described automated whole genome sequence (WGS)-based serotyping bioinformatics tool, PneumoCaT, we identified and investigated seven clinical isolates (three from blood cultures) of non-pneumococcal streptococci containing a highly homologous tts and included them in a study panel of 20 isolates which included a 11 further clinical isolates of S...
2017: PeerJ
https://www.readbyqxmd.com/read/28727778/in-vitro-study-of-accuracy-of-subaxial-cervical-pedicle-screw-insertion-using-calipers-based-on-the-gravity-line
#2
Xiang Yao, Shiqing Liu
OBJECT: There is a high probability of iatrogenic perforation of the vertebral pedicle wall during the application of subaxial cervical pedicle screw (CPS). The goal of this study was to evaluate the accuracy of CPS insertion at C3-C7 in vitro using novel calipers based on the gravity line. METHODS: Nine cadaveric cervical spines underwent computed tomography scanning and preoperative design. A lateral fluoroscopic view was taken to measure the intra-operative sagittal angle by C-arm with hanging cross structured K-wires...
2017: PloS One
https://www.readbyqxmd.com/read/28726114/sex-related-differences-in-serum-matrix-metalloproteinase-9-screening-non-calcified-and-mixed-coronary-atherosclerotic-plaques-in-outpatients-with-chest-pain
#3
Chun Gu, Fang Wang, Zhihui Hou, Bin Lv, Yang Wang, Xiangfeng Cong, Xi Chen
The objective of this study is to evaluate the clinical feasibility of serum matrix metalloproteinase-9 (MMP-9) for screening plaque composition as assessed by coronary computed tomography angiography (CCTA) in outpatients with chest pain,and the effects of sex on this feasibility. Eight hundred and sixty-two consecutive outpatients with chest pain were divided into three groups according to the results of CCTA: non-plaque (NP, n = 474), calcified plaques (CPs, n = 179), non-calcified and mixed plaques (NCPs and MPs, n = 209)...
July 19, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28724411/a-qualitative-study-exploring-perceptions-and-attitudes-of-community-pharmacists-about-extended-pharmacy-services-in-lahore-pakistan
#4
Furqan K Hashmi, Mohamed Azmi Hassali, Adnan Khalid, Fahad Saleem, Hisham Aljadhey, Zaheer Ud Din Babar, Mohammad Bashaar
BACKGROUND: In recent decades, community pharmacies reported a change of business model, whereby a shift from traditional services to the provision of extended roles was observed. However, such delivery of extended pharmacy services (EPS) is reported from the developed world, and there is scarcity of information from the developing nations. Within this context, the present study was aimed to explore knowledge, perception and attitude of community pharmacists (CPs) about EPS and their readiness and acceptance for practice change in the city of Lahore, Pakistan...
July 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28719847/high-photocatalytic-activity-of-hierarchical-sio2-c-doped-tio2-hollow-spheres-in-uv-and-visible-light-towards-degradation-of-rhodamine-b
#5
Ying Zhang, Juanrong Chen, Li Hua, Songjun Li, Xuanxuan Zhang, Weichen Sheng, Shunsheng Cao
Ongoing research activities are targeted to explore high photocatalytic activity of TiO2-based photocatalysts for the degradation of environmental contaminants under UV and visible light irradiation. In this work, we devise a facile, cost-effective technique to in situ synthesize hierarchical SiO2@C-doped TiO2 (SCT) hollow spheres for the first time. This strategy mainly contains the preparation of monodisperse cationic polystyrene spheres (CPS), sequential deposition of inner SiO2, the preparation of the sandwich-like CPS@SiO2@CPS particles, and formation of outer TiO2...
July 10, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28715776/gender-differences-in-the-real-world-effectiveness-of-smoking-cessation-medications-findings-from-the-2010-2011-tobacco-use-supplement-to-the-current-population-survey
#6
Philip H Smith, Ju Zhang, Andrea H Weinberger, Carolyn M Mazure, Sherry A McKee
BACKGROUND: Meta-analyses of clinical trial data have identified clinically relevant gender differences in the efficacy of smoking cessation pharmacotherapy. It is unclear whether these findings are generalizable to smokers quitting in real-world contexts. METHODS: Using Tobacco Use Supplement to the Current Population Survey (TUS-CPS) 2010-2011 cross-sectional data, we generated propensity score matched samples of smokers who quit either unassisted by medication, using only varenicline, or using only transdermal nicotine patch (TNP)...
July 10, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28714910/minding-the-cyber-physical-gap-model-based-analysis-and-mitigation-of-systemic-perception-induced-failure
#7
Yaniv Mordecai, Dov Dori
The cyber-physical gap (CPG) is the difference between the 'real' state of the world and the way the system perceives it. This discrepancy often stems from the limitations of sensing and data collection technologies and capabilities, and is inevitable at some degree in any cyber-physical system (CPS). Ignoring or misrepresenting such limitations during system modeling, specification, design, and analysis can potentially result in systemic misconceptions, disrupted functionality and performance, system failure, severe damage, and potential detrimental impacts on the system and its environment...
July 17, 2017: Sensors
https://www.readbyqxmd.com/read/28707877/free-energy-driven-lock-open-assembly-based-optical-dna-sensor-for-cancer-related-microrna-detection-with-a-shortened-time-to-result
#8
Xiyu Zhu, Ruoyu Wang, Xiaohong Zhou, Hanchang Shi
Quantification of cancer biomarker microRNAs (miRs) by exquisitely designed biosensors with a short time-to-result is of great clinical significance. With immobilized capture probes (CPs) and fluorescent labeled signal probes (SPs), surface involved sandwich-type (SST) biosensors serve as powerful tools for rapid, highly sensitive and selective detection of miR in complex matrices as opposed to the conventional techniques. One key challenge for such SST biosensors is the existence of false negative signals when the amount of miRs exceeds SPs in solution phase for a surface with limited number of CP...
July 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28707475/exit-outcomes-for-probation-supervised-youth-in-foster-care-an-examination-of-past-child-protection-involvement
#9
Andrea Lane Eastman, Emily Putnam-Hornstein
Research on youth in foster care has focused on those placed for reasons of maltreatment rather than delinquency, yet most states provide foster care services to youth under probation supervision. This analysis generated knowledge about youth in probation-supervised foster care (PSFC) in California by examining the relationship between past child protective services (CPS) involvement and exit type. CPS records were extracted to identify 17-year-old youths in PSFC between 2008 and 2012 ( N = 11,188). The relationship between allegations of maltreatment and exit type was assessed using regression models...
January 1, 2017: Child Maltreatment
https://www.readbyqxmd.com/read/28704798/experimental-studies-on-possible-regulatory-role-of-nitric-oxide-on-the-differential-effects-of-chronic-predictable-and-unpredictable-stress-on-adaptive-immune-responses
#10
Tarun Thakur, Kavita Gulati, Nishant Rai, Arunabha Ray
The present study was designed to investigate the effects of chronic predictable stress (CPS) and chronic unpredictable stress (CUS) on immunological responses in KLH-sensitized rats and involvement of NOergic signaling pathways mediating such responses. Male Wistar rats (200-250g) were exposed to either CPS or CUS for 14days and IgG antibody levels and delayed type hypersensitivity (DTH) response was determined to assess changes in adaptive immunity. To evaluate the role of nitric oxide during such immunomodulation, biochemical estimation of stable metabolite of nitric oxide (NOx) and 3-nitrotyrosine (3-NT, a marker of peroxynitrite formation) were done in both blood and brain...
July 10, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28702528/stability-and-growth-mechanism-of-self-assembling-putative-antifreeze-cyclic-peptides
#11
Z Faidon Brotzakis, Mascha Gehre, Ilja K Voets, Peter G Bolhuis
Cyclic peptides (CPs) that self-assemble in nanotubes can be candidates for use as antifreeze proteins. Based on the cyclic peptide sequence cyclo-[(l-LYS-d-ALA-l-LEU-d-ALA)2], which can stack into nanotubes, we propose a putative antifreeze cyclic peptide (AFCP) sequence, cyclo-[(l-LYS-d-ALA)2-(l-THR-d-ALA)2], containing THR-ALA-THR ice binding motifs. Using molecular dynamics simulations we investigate the stability of these cyclic peptides and their growth mechanism. Both nanotube sequences get more stable as a function of size...
July 12, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28697467/smoking-prevalence-and-seizure-control-in-chinese-males-with-epilepsy
#12
Hui Gao, Josemir W Sander, Xudong Du, Jiani Chen, Cairong Zhu, Dong Zhou
Smoking has a negative effect on most diseases, yet it is under-investigated in people with epilepsy; thus its role is not clear in the general population with epilepsy. We performed a retrospective pilot study on males with epilepsy to determine the smoking rate and its relationship with seizure control using univariate analysis to calculate odds ratios (ORs) and also used a multi-variate logistic regression model. The smoking rate in our sample of 278 individuals was 25.5%, which is lower than the general Chinese population smoking rate among males of 52...
July 7, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28696102/release-and-gas-particle-partitioning-behaviors-of-short-chain-chlorinated-paraffins-sccps-during-the-thermal-treatment-of-polyvinyl-chloride-flooring
#13
Faqiang Zhan, Haijun Zhang, Jing Wang, Jiazhi Xu, Heping Yuan, Yuan Gao, Fan Su, Jiping Chen
Chlorinated paraffin (CP) mixture is a common additive in polyvinyl chloride (PVC) products as a plasticizer and flame retardant. During the PVC plastic life cycle, intentional or incidental thermal processes inevitably cause an abrupt release of short-chain CPs (SCCPs). In this study, the thermal processing of PVC plastics was simulated by heating PVC flooring at 100-200 °C in a chamber. The 1-h thermal treatment caused the release of 1.9%-10.7% of the embedded SCCPs. A developed emission model indicated that SCCP release was mainly controlled by material-gas partitioning at 100 °C...
July 11, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28694854/antimicrobial-resistant-pattern-and-capsular-typing-of-streptococcus-pneumoniae-isolated-from-children-in-sistan-baluchestan
#14
Zahra Gharailoo, Seyed Fazlollah Mousavi, Niloofar Halvani, Mohammad Mehdi Feizabadi
BACKGROUND: Ankyloglossia is an anatomic developmental anomaly determining by thick and short, fi brotic ferenum. Tongue changes have severe eff ects on occlusion and oropharyngeal structures. The aim of this study was to evaluate the position of hyoid in children 7-11 years` old with ankyloglossia in lateral cephalometric radiographs. MATERIALS AND METHOD: In this study 260 nasopharyngeal swabs were taken from non-vaccinated healthy children between 6 months to 6 years old at medical centers in Sistan-Baluchestan during August 2013 to January 2014...
September 2016: Mædica
https://www.readbyqxmd.com/read/28693930/the-prevalence-of-rectal-carriage-of-klebsiella-pneumoniae-amongst-diabetic-patients-and-their-clinical-relevance-in-taiwan-a-five-year-prospective-study
#15
Yu-Tsung Huang, Ju-Ying Jiang, Meng-Shiuan Hsu, Hsin-Sui Hsu, Chun-Hsing Liao, Po-Ren Hsueh
BACKGROUND/PURPOSE: Pyogenic liver abscess (PLA) and bacteremia caused by Klebsiella pneumoniae is a common complication among patients with diabetes mellitus (DM). The aim of this study is to investigate the prevalence of rectal carriage and serotype distribution of K. pneumoniae amongst DM patients and their clinical relevance. METHODS: We prospectively collected rectal swabs for K. pneumoniae culture in asymptomatic DM patients from March 2008 to June 2009. Seven capsular serotypes that were commonly associated with PLA were determined by capsular polysaccharide synthesis (cps) genotyping...
June 29, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28691896/assessing-the-risk-of-cytomegalovirus-dnaaemia-in-allogeneic-stem-cell-transplant-recipients-by-monitoring-oxidative-stress-markers-in-plasma
#16
Alberto Talaya, Carlos Solano, Estela Giménez, José Luis García Giménez, Víctor Vinuesa, Juan Alberola, Federico V Pallardó, David Navarro
The level of antioxidants, such as thiol-containing tripeptide glutathione (GSH), in cytomegalovirus (CMV)-infected cells is notably increased. We previously showed that GSH levels in plasma, as measured by untargeted 1H nuclear magnetic resonance, are higher in allogeneic stem cell transplant (allo-SCT) recipients who subsequently develop CMV viraemia. We hypothesized that the net level of oxidative-stress markers present in plasma may be reduced in patients who develop CMV DNAaemia compared to those who do not...
July 10, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28689602/preparation-and-efficacy-assessment-of-malva-nut-polysaccharide-for-skin-hydrating-products
#17
M Kanlayavattanakul, K Fungpaisalpong, M Pumcharoen, N Lourith
INTRODUCTION: Scaphium scaphigerum or malva nut has long been served in Chinese medicine. However, the use of this herb in modern health care applications has, to date, been rarely reported. MATERIALS AND METHODS: Maceration of the herb in water afforded malva nut polysaccharide which was standardized. Safety and skin hydrating efficacy of the polysaccharide and products were evaluated in human volunteers. RESULTS: Malva nut polysaccharide (41...
July 6, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28689259/differential-diagnosis-of-parkinsonism-by-a-combined-use-of-diffusion-kurtosis-imaging-and-quantitative-susceptibility-mapping
#18
Kenji Ito, Chigumi Ohtsuka, Kunihiro Yoshioka, Hiroyuki Kameda, Suguru Yokosawa, Ryota Sato, Yasuo Terayama, Makoto Sasaki
PURPOSE: We investigated whether diffusion kurtosis imaging (DKI) and quantitative susceptibility mapping (QSM) could detect pathological changes that occur in Parkinson's disease (PD), multiple system atrophy with predominant parkinsonism (MSA-P) or predominant cerebellar ataxia (MSA-C), and progressive supranuclear palsy syndrome (PSPS) and thus be used for differential diagnosis that is often difficult. METHODS: Seventy patients (41 with PD, 6 with MSA-P, 7 with MSA-C, 16 with PSPS) and 20 healthy controls were examined using a 3...
July 8, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28682842/dual-isotope-spect-study-with-epilepsy-patients-using-semiconductor-spect-system
#19
Tohru Shiga, Atsuro Suzuki, Kotarou Sakurai, Tsugiko Kurita, Wataru Takeuchi, Takuya Toyonaga, Kenji Hirata, Keiji Kobashi, Chietsugu Katoh, Naoki Kubo, Nagara Tamaki
PURPOSE: We developed a prototype CdTe SPECT system with 4-pixel matched collimator for brain study. This system provides high-energy-resolution (6.6%), high-sensitivity (220 cps/MBq/head), and high-spatial-resolution images. The aim of this study was to evaluate dual-isotope study of CBF and central benzodiazepine receptor (BZR) images using Tc-ECD and I-IMZ with the new SPECT system in patients with epilepsy comparing with single-isotope study using the conventional scintillation gamma camera...
July 6, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28681475/the-interplay-between-housing-stability-and-child-separation-implications-for-practice-and-policy
#20
Debra J Rog, Kathryn A Henderson, Laurel M Lunn, Andrew L Greer, Mei Ling Ellis
Greater understanding of how residential stability affects child separation and reunification among homeless families can guide both child welfare and homeless policy and practice. This article draws upon two longitudinal studies examining services and housing for homeless families and their relationship to family and housing stability. Both studies were conducted in the same state at roughly the same time with similar instruments. The first study, examining families' experiences and outcomes following entry into the homeless service system in three counties in Washington State, found that at 18 months following shelter entry, families that are intact with their children were significantly more likely to be housed in their own housing (46%) than families that were separated from one or more of their children (31%)...
July 5, 2017: American Journal of Community Psychology
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