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https://www.readbyqxmd.com/read/29763823/synthesis-of-uniform-ag-nanosponges-and-its-sers-application
#1
Qingli Huang, Wenxian Wei, LiLi Wang, Huabo Chen, Ting Li, Xiashi Zhu, Yongping Wu
With the aid of amino acid, various Ag nanostructures were successfully synthesized via the reaction between silver nitrate and hydrazine hydrate at room temperature. The as-prepared products were characterized by X-ray diffraction and scanning electron microscopy. It was found that the morphology of the as-prepared Ag products depended on the sorts of amino acid and solvents. The uniform Ag nanosponges could be obtained in glycol with aid of glycine. Using rhodamine 6G (R6G) as probe, the surface-enhanced Raman scattering (SERS) performance was also investigated, which showed that the uniform Ag nanosponges exhibited an intensive and enhanced Raman scattering...
May 9, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29730602/deep-learning-radiomics-of-shear-wave-elastography-significantly-improved-diagnostic-performance-for-assessing-liver-fibrosis-in-chronic-hepatitis-b-a-prospective-multicentre-study
#2
Kun Wang, Xue Lu, Hui Zhou, Yongyan Gao, Jian Zheng, Minghui Tong, Changjun Wu, Changzhu Liu, Liping Huang, Tian'an Jiang, Fankun Meng, Yongping Lu, Hong Ai, Xiao-Yan Xie, Li-Ping Yin, Ping Liang, Jie Tian, Rongqin Zheng
OBJECTIVE: We aimed to evaluate the performance of the newly developed deep learning Radiomics of elastography (DLRE) for assessing liver fibrosis stages. DLRE adopts the radiomic strategy for quantitative analysis of the heterogeneity in two-dimensional shear wave elastography (2D-SWE) images. DESIGN: A prospective multicentre study was conducted to assess its accuracy in patients with chronic hepatitis B, in comparison with 2D-SWE, aspartate transaminase-to-platelet ratio index and fibrosis index based on four factors, by using liver biopsy as the reference standard...
May 5, 2018: Gut
https://www.readbyqxmd.com/read/29701452/enhancing-catalyzed-decomposition-of-na2co3-with-co2mnox-nanowires-decorated-carbon-fibers-for-advanced-na-co2-batteries
#3
Cong Fang, Jianmin Luo, Chengbin Jin, Huadong Yuan, Ouwei Sheng, Hui Huang, Yongping Gan, Yang Xia, Chu Liang, Jun Zhang, Wenkui Zhang, Xinyong Tao
The metal-CO2 batteries, especially Na-CO2 batteries come into sight owing to their high energy density, ability for CO2 capture and the abundance of sodium resource. Besides the sluggish electrochemical reactions at gas cathodes and the instability of electrolyte at high voltage, the final discharge product Na2CO3 is solid and poor conductor of electricity, which may cause the high overpotential and poor cycle performance for Na-CO2 batteries. The promoting decomposition of Na2CO3 should be an efficient strategy to enhance the electrochemical performance...
April 27, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29694145/prediction-of-intrinsic-ferromagnetic-ferroelectricity-in-a-transition-metal-halide-monolayer
#4
Chengxi Huang, Yongping Du, Haiping Wu, Hongjun Xiang, Kaiming Deng, Erjun Kan
The realization of multiferroics in nanostructures, combined with a large electric dipole and ferromagnetic ordering, could lead to new applications, such as high-density multistate data storage. Although multiferroics have been broadly studied for decades, ferromagnetic ferroelectricity is rarely explored, especially in two-dimensional (2D) systems. Here we report the discovery of 2D ferromagnetic ferroelectricity in layered transition-metal halide systems. On the basis of first-principles calculations, we reveal that a charged CrBr_{3} monolayer exhibits in-plane multiferroicity, which is ensured by the combination of orbital and charge ordering as realized by the asymmetric Jahn-Teller distortions of octahedral Cr─Br_{6} units...
April 6, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29692176/mg-2-b-2-o-5-nanowire-enabled-multifunctional-solid-state-electrolytes-with-high-ionic-conductivity-excellent-mechanical-properties-and-flame-retardant-performance
#5
Ouwei Sheng, Chengbin Jin, Jianmin Luo, Huadong Yuan, Hui Huang, Yongping Gan, Jun Zhang, Yang Xia, Chu Liang, Wenkui Zhang, Xinyong Tao
High ionic conductivity, satisfactory mechanical properties, and wide electrochemical windows are crucial factors for composite electrolytes employed in solid-state lithium-ion batteries (SSLIBs). Based on these considerations, we fabricate Mg2 B2 O5 nanowire enabled poly(ethylene oxide) (PEO)-based solid-state electrolytes (SSEs). Notably, these SSEs have enhanced ionic conductivity and a large electrochemical window. The elevated ionic conductivity is attributed to the improved motion of PEO chains and the increased Li migrating pathway on the interface between Mg2 B2 O5 and PEO-LiTFSI...
April 25, 2018: Nano Letters
https://www.readbyqxmd.com/read/29607256/the-modern-spectrum-of-biopsy-proven-renal-disease-in-chinese-diabetic-patients-a-retrospective-descriptive-study
#6
Diankun Liu, Ting Huang, Nan Chen, Gang Xu, Ping Zhang, Yang Luo, Yongping Wang, Tao Lu, Long Wang, Mengqi Xiong, Jian Geng, Sheng Nie
Background: Renal biopsies performed in diabetic patients are increasing and becoming more complex. Comprehensive data on modern spectrum of biopsy-proven renal disease in Chinese diabetic patients are lacking. Methods: In a nationwide renal biopsy survey including 71,151 native biopsies from 2004 to 2014, diabetic patients were identified according to the clinical diagnosis from referral records. The clinical data were extracted from referral records and pathological reports...
2018: PeerJ
https://www.readbyqxmd.com/read/29500859/aberrant-kif20a-expression-might-independently-predict-poor-overall-survival-and-recurrence-free-survival-of-hepatocellular-carcinoma
#7
Mingqin Lu, Xiaoying Huang, Yongping Chen, Yangyang Fu, Chaona Xu, Wei Xiang, Cheng Li, Shengguo Zhang, Chang Yu
Kinesin family member 20A (KIF20A) is an essential regulator of cytokinesis. In this study, by performing a retrospective study based on data from the Cancer Genome Atlas (TCGA)-Liver and Hepatocellular Carcinoma (LIHC) cohort, we tried to assess the independent prognostic value of KIF20A in terms of overall survival (OS) and recurrence-free survival (RFS). Results showed that normal liver tissues had very low KIF20A expression compared with normal tissues in other cohorts in TCGA. However, the primary HCC tissues (N = 371) had significantly elevated KIF20A expression than normal liver tissues (N = 50)...
April 2018: IUBMB Life
https://www.readbyqxmd.com/read/29495966/the-consensus-on-indications-conditioning-regimen-and-donor-selection-of-allogeneic-hematopoietic-cell-transplantation-for-hematological-diseases-in-china-recommendations-from-the-chinese-society-of-hematology
#8
REVIEW
Lanping Xu, Hu Chen, Jing Chen, Mingzhe Han, He Huang, Yongrong Lai, Daihong Liu, Qifa Liu, Ting Liu, Ming Jiang, Hanyun Ren, Yongping Song, Zimin Sun, Jianmin Wang, Depei Wu, Daobin Zhou, Ping Zou, Kaiyan Liu, Xiaojun Huang
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is widely used to treat malignant hematological neoplasms and non-malignant hematological disorders. Approximately, 5000 allo-HSCT procedures are performed in China annually. Substantial progress has been made in haploidentical HSCT (HID-HSCT), pre-transplantation risk stratification, and donor selection in allo-HSCT, especially after the establishment of the "Beijing Protocol" HID-HSCT system. Transplant indications for selected subgroups in low-risk leukemia or severe aplastic anemia (SAA) differ from those in the Western world...
March 2, 2018: Journal of Hematology & Oncology
https://www.readbyqxmd.com/read/29486441/analyzing-the-carbon-mitigation-potential-of-tradable-green-certificates-based-on-a-tgc-ffsro-model-a-case-study-in-the-beijing-tianjin-hebei-region-china
#9
Cong Chen, Ying Zhu, Xueting Zeng, Guohe Huang, Yongping Li
Contradictions of increasing carbon mitigation pressure and electricity demand have been aggravated significantly. A heavy emphasis is placed on analyzing the carbon mitigation potential of electric energy systems via tradable green certificates (TGC). This study proposes a tradable green certificate (TGC)-fractional fuzzy stochastic robust optimization (FFSRO) model through integrating fuzzy possibilistic, two-stage stochastic and stochastic robust programming techniques into a linear fractional programming framework...
July 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29474354/bombyx-mori-histone-methyltransferase-bmash2-is-essential-for-silkworm-pirna-mediated-sex-determination
#10
Zhiqian Li, Lang You, Dong Yan, Anthony A James, Yongping Huang, Anjiang Tan
Sex determination is a hierarchically-regulated process with high diversity in different organisms including insects. The W chromosome-derived Fem piRNA has been identified as the primary sex determination factor in the lepidopteran insect, Bombyx mori, revealing a distinctive piRNA-mediated sex determination pathway. However, the comprehensive mechanism of silkworm sex determination is still poorly understood. We show here that the silkworm PIWI protein BmSiwi, but not BmAgo3, is essential for silkworm sex determination...
February 2018: PLoS Genetics
https://www.readbyqxmd.com/read/29434730/clinical-and-pathological-characteristics-of-igg4-related-interstitial-lung-disease
#11
Xiaoting Lv, Feng Gao, Qicai Liu, Sheng Zhang, Zhihua Huang, Yongping Zhu, Haiyang Zong, Quwen Li, Sanyan Li
IgG4-related interstitial lung disease (IgG4-RILD), which is characterized by increased IgG4 levels, IgG4+ plasma cell infiltration and irregular whorled fibrosis, is a recently described lung disorder that belongs to the group of systemic fibroinflammatory IgG4-related diseases (IgG4-RD). The aim of the present study was to improve the current knowledge regarding the specific clinical and histopathological characteristics of IgG4-RILD and to investigate its underlying immune mechanism in vivo . A total of 7 patients newly diagnosed with IgG4-RILD were enrolled in the present study (4 men and 3 women; mean age, 57 years; range, 29-71 years)...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29384927/efficacy-and-safety-of-micafungin-for-the-treatment-of-patients-with-proven-or-probable-invasive-aspergillosis-a-non-comparative-multicenter-phase-iv-open-label-study
#12
MULTICENTER STUDY
Yu Ji, Yongping Song, Fang Zhou, Ting Liu, Ming Jiang, Xielan Zhao, Xiaojun Huang
INTRODUCTION: Few studies have assessed the efficacy and safety of micafungin in patients with proven or probable invasive aspergillosis (IA). This was the aim of the current study, which was conducted in 22 hospitals in China, where micafungin was approved for treatment of IA in 2006. METHODS: This was a non-comparative, phase IV open-label study (NCT02646774). Eligible patient were adults with proven or probable IA. Efficacy endpoints included rates of overall treatment success (primary endpoint) and clinical improvement, fungal clearance, mortality, and the site of Aspergillus infection (all secondary endpoints)...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29383157/celecoxib-targets-breast-cancer-stem-cells-by-inhibiting-the-synthesis-of-prostaglandin-e-2-and-down-regulating-the-wnt-pathway-activity
#13
Chaolin Huang, Yuanhong Chen, Hang Liu, Jing Yang, Xuejing Song, Junping Zhao, Na He, Chengji J Zhou, Yongping Wang, Changjiang Huang, Qiaoxiang Dong
Pharmacological targeting of breast cancer stem cells (CSCs) is highly promising for the treatment of breast cancer, as the small population of CSCs is responsible for tumor initiation, progression, recurrence and chemo-resistance. Celecoxib is one of the most commonly used non-steroidal anti-inflammatory drugs (NSAIDs), which have chemo-preventive activity against cancers, including breast cancer and colorectal cancer. However, the mechanisms by which NSAIDs exert its cancer prevention effects have yet been completely understood...
December 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/29352288/phospholipid-scramblase-1-interacts-with-influenza-a-virus-np-impairing-its-nuclear-import-and-thereby-suppressing-virus-replication
#14
Weiyu Luo, Jie Zhang, Libin Liang, Guangwen Wang, Qibing Li, Pengyang Zhu, Yuan Zhou, Junping Li, Yuhui Zhao, Nan Sun, Shanyu Huang, Chenchen Zhou, Yu Chang, Pengfei Cui, Pucheng Chen, Yongping Jiang, Guohua Deng, Zhigao Bu, Chengjun Li, Li Jiang, Hualan Chen
Transcription and replication of the influenza A virus (IAV) genome occur in the nucleus of infected cells and are carried out by the viral ribonucleoprotein complex (vRNP). As a major component of the vRNP complex, the viral nucleoprotein (NP) mediates the nuclear import of the vRNP complex via its nuclear localization signals (NLSs). Clearly, an effective way for the host to antagonize IAV infection would be by targeting vRNP nuclear import. Here, we identified phospholipid scramblase 1 (PLSCR1) as a binding partner of NP by using a yeast two-hybrid (Y2H) screen...
January 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29337139/identification-of-yellow-gene-family-in-agrotis-ipsilon-and-functional-analysis-of-aiyellow-y-by-crispr-cas9
#15
Xi'en Chen, Yanghui Cao, Shuai Zhan, Yong Zhang, Anjiang Tan, Yongping Huang
The yellow gene family has been identified in several model insects, but yellow genes were poorly identified in non-model insects and the functions of yellow genes are largely unknown. In this study, we identified seven yellow genes in an important agricultural pest Agrotis ipsilon. Each gene encodes a protein containing a major royal jelly domain. Phylogenetic analysis defined these genes as yellow-y, -b, -b2, -c, -d, -e, and -h, respectively. The A. ipsilon yellow genes yellow-b, -b2, and -c were stably expressed in all developmental stages and tissues analyzed, whereas the other four yellow genes had unique expression patterns, suggesting distinct physiological roles of each gene...
March 2018: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29316730/novel-synthesis-of-slightly-fluorinated-graphene-quantum-dots-with-luminescent-and-paramagnetic-properties-through-thermal-cutting-of-fluorinated-graphene
#16
Qian Feng, Wenqing Xiao, Yuan Liu, Yongping Zheng, Yuda Lin, Jiaxin Li, Qingying Ye, Zhigao Huang
A novel approach has been developed to synthesize slightly fluorinated graphene quantum dots (GQDs-F) through thermal cutting of highly fluorinated graphene. The fluorinated graphene with substantial structure defects is fragile and is readily attacked. The direct evaporation of abundant CFn ( n = 2, 3) groups near structure defects lead to the loss of adjacent skelton C atoms, and the fluorinated graphene can be thermally cut into GQDs-F with a relatively uniform nanosize in pyrolysis at 810 K. The GQDs-F with a low F/C atomic ratio of ca...
January 8, 2018: Materials
https://www.readbyqxmd.com/read/29297099/assessment-of-corneal-biomechanical-properties-with-inflation-test-using-optical-coherence-tomography
#17
Like Wang, Lei Tian, Yanping Huang, Yifei Huang, Yongping Zheng
Biomechanical properties are important for the cornea to maintain its normal shape and function. There is still a need to develop better methods for accurate measurement of corneal mechanical properties. In this study, we propose to introduce the optical coherence tomography (OCT) in inflation test for the imaging of corneal deformation in order to measure its biomechanical properties. Ten cornea-mimicking silicone phantoms with different stiffness and five fresh porcine corneas were tested using the proposed method...
February 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29288754/microrna-14-regulates-larval-development-time-in-bombyx-mori
#18
Zulian Liu, Lin Ling, Jun Xu, Baosheng Zeng, Yongping Huang, Peng Shang, Anjiang Tan
MicroRNAs (miRNA) regulate multiple physiological processes including development and metamorphosis in insects. In the current study, we demonstrate that a conserved invertebrate miRNA-14 (miR-14) plays an important role in ecdysteroid regulated development in the silkworm Bombyx mori, a lepidopteran model insect. Ubiquitous transgenic overexpression of miR-14 using the GAL4/UAS system resulted in delayed silkworm larval development and smaller body size of larva and pupa with decrease in ecdysteriod titers...
February 2018: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29286155/mesenchymal-stem-cells-reverse-high%C3%A2-fat-diet%C3%A2-induced-non%C3%A2-alcoholic-fatty-liver-disease-through-suppression-of-cd4-t-lymphocytes-in-mice
#19
Huafeng Wang, Huan Zhang, Biao Huang, Guolin Miao, Xiaoyan Yan, Gang Gao, Yongping Luo, Huize Chen, Wei Chen, Luhong Yang
Although the multipotency of mesenchymal stem cells (MSCs) makes them an attractive choice for clinical applications, immune modulation is an important factor affecting MSC transplantation. At present, the effect of treatment with MSCs on non‑alcoholic fatty liver disease (NAFLD) has received little attention. In the present study, a compact bone‑derived method was used to isolate mouse MSCs (mMSCs) and a high‑fat diet was used to establish a mouse model of NAFLD. Immunophenotypic features of mMSCs were analyzed using flow cytometry...
March 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29259988/increased-circulating-th17-but-decreased-cd4-foxp3-treg-and-cd19-cd1d-hi-cd5-breg-subsets-in-new-onset-graves-disease
#20
Jing Qin, Jin Zhou, Chenling Fan, Na Zhao, Yongping Liu, Shuo Wang, Xuejiao Cui, Mingshi Huang, Haixia Guan, Yushu Li, Zhongyan Shan, Weiping Teng
Th17 and regulatory lymphocyte subsets such as Tregs and Bregs have been reported to play important roles in autoimmune diseases. The aim of this work was to perform quantitative studies of circulating Th17, Tregs, and Bregs in patients with new-onset Graves' disease (GD). Twenty GD patients and 20 healthy controls were involved in this study. Blood samples were taken for flow cytometry detection of CD4+ IL-17+ Th17, CD4+ Foxp3+ Tregs, and CD19+ CD1dhi CD5+ Bregs and meanwhile, for real-time PCR measurement of gene expressions of ROR γ t, IL-17 and IL-10...
2017: BioMed Research International
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